CA2005451A1 - Laser therapeutic apparatus and method - Google Patents
Laser therapeutic apparatus and methodInfo
- Publication number
- CA2005451A1 CA2005451A1 CA002005451A CA2005451A CA2005451A1 CA 2005451 A1 CA2005451 A1 CA 2005451A1 CA 002005451 A CA002005451 A CA 002005451A CA 2005451 A CA2005451 A CA 2005451A CA 2005451 A1 CA2005451 A1 CA 2005451A1
- Authority
- CA
- Canada
- Prior art keywords
- set forth
- laser beam
- mhz
- infrared laser
- pulses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 23
- 230000001225 therapeutic effect Effects 0.000 title description 4
- 201000010099 disease Diseases 0.000 claims abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 11
- 230000009885 systemic effect Effects 0.000 claims abstract description 10
- 239000006227 byproduct Substances 0.000 claims abstract description 3
- 230000005855 radiation Effects 0.000 claims description 13
- 241001465754 Metazoa Species 0.000 claims description 6
- 230000006872 improvement Effects 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 206010028980 Neoplasm Diseases 0.000 description 6
- 241000700159 Rattus Species 0.000 description 6
- 230000004075 alteration Effects 0.000 description 4
- 201000011510 cancer Diseases 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000012546 transfer Methods 0.000 description 4
- 230000003902 lesion Effects 0.000 description 3
- 238000002595 magnetic resonance imaging Methods 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- 238000001574 biopsy Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 230000008263 repair mechanism Effects 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 230000001173 tumoral effect Effects 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- XOJVVFBFDXDTEG-UHFFFAOYSA-N Norphytane Natural products CC(C)CCCC(C)CCCC(C)CCCC(C)C XOJVVFBFDXDTEG-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 206010039491 Sarcoma Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000005465 channeling Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000009442 healing mechanism Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000001225 nuclear magnetic resonance method Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 238000005476 soldering Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/067—Radiation therapy using light using laser light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0644—Handheld applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
- A61N2005/066—Radiation therapy using light characterised by the wavelength of light used infrared far infrared
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
ABSTRACT OF THE DISCLOSURE
An apparatus and method (10) for treating cancerous tissues and other systemic diseases through the application of an infrared laser beam to the target tissue through the biological circuit of the patient. The output of an oscillator (20) is connected to the input of a frequency selector (30) to selectively adjust the pulse frequency. The pulse train (40) is selected to be between 0.5 MHz and 7.5 MHz with a relatively low duty cycle to avoid thermic energy from making the process an uncomfortable one. The pulse signal, after being amplified, is fed to a transistor (50) that drives a laser diode (60) thereby modulating the output beam. An ultraviolet filter (70) is used to block any unwanted harmonic byproduct. The laser beam is applied substantially perpendicularly to the surface of the patient's skin and in the area in close proximity to the VICC biological circuit that would more efficiently carry the laser energy to the target tissue. The procedure is repeated periodically and its process monitored through conventional magnetic resonance images techniques or other accepted methods.
An apparatus and method (10) for treating cancerous tissues and other systemic diseases through the application of an infrared laser beam to the target tissue through the biological circuit of the patient. The output of an oscillator (20) is connected to the input of a frequency selector (30) to selectively adjust the pulse frequency. The pulse train (40) is selected to be between 0.5 MHz and 7.5 MHz with a relatively low duty cycle to avoid thermic energy from making the process an uncomfortable one. The pulse signal, after being amplified, is fed to a transistor (50) that drives a laser diode (60) thereby modulating the output beam. An ultraviolet filter (70) is used to block any unwanted harmonic byproduct. The laser beam is applied substantially perpendicularly to the surface of the patient's skin and in the area in close proximity to the VICC biological circuit that would more efficiently carry the laser energy to the target tissue. The procedure is repeated periodically and its process monitored through conventional magnetic resonance images techniques or other accepted methods.
Description
200~4'~1 1. TITLE: LASER THERAPEUTIC APPARATUS AND METHOD
II. TECHNICAL FIELD
The present invention relates to laser devices, and more particularly, to such devices that are used to treat cancer and other systemic diseases.
III. BACKGROUND ART.
Applicant believes that the closest reference corresponds to U.S.
patent No. 4,724,835 issued to Liss et al on February 16, 1988. However, it differs from the present invention because this patented device includes a circuit that operates the infrared laser diode at a relatively high voltage with low pulse frequency. Also, while acknowledging or suggesting that ~he rise and/or fall time of the pulse may have an effect on the therapeutic effect of the above referenced patented device, it nevertheless lacks any mechanism (electronic or otherwise) to optimize this parameter. In fact, the patentees acknowledge their lack of precise knowledge for the results obtained. Finally, in Liss' patent, the laser beam is applied specifically on the injury area with the consequent inadequacy for uniform trea~ment of systemic illnesses at a distance.
Other patents describing therapeutic devices that utilize the laser technology concentrate on the cutting and burning characteristics of these beams at their different wavelengths which are not the subject of the prc8cnt invention, None of these patents suggest the novel features of the prcscnt invention.
ZOOS~Sl Another related reference is the article written by Dr. Bjorn E.W.
Northerstrom entitled "Biokinetic Impacts on Structure and Imaging of the Lung: The Concept of Biologically Closed Electric Circuits" and published in the September, 1985 issue of the American 30urnal of the Roentgen Ray Society. In this article, the concept of the Vascular-Interstitial Closed Circuit (VICC) is described. The VICC concept explains the different voltage potential drops observed by Dr. Northerstrom in the different tissues studied with direct electric current. This circuit comprises the entire circulatory system and through which the relatively low electric resistance of the plasma allows the flow of ~he direct current.
Another relevant reference in the related art includes the chapter authorèd by Dr. Anthony S-Y Leong entitled Microwave Irradiation in Histopathology in the volume 23, of part 2, of the Pathology Annual published Appleton & Lange, Norwalk, CN. In particular, on the last paragraph of page 214 the author acknowledges the effect of field-induced alterations in macromolecular hydrogen bonding, proton tunnelling and disruption of bound water may induce alterations in biologic systems. This article, however, relates only to microwave fields.
For studies relating to lower frequency (ultra-sound on fractures) treatments, the closest reference known by Applicant corresponds to the article authored by A.A. Pilla et al in the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. (IEEE Cat. No. 88CH2566-8), New Orleans, LA 1988.
IV. S~ RY OF ~HE INVENTION
It is one of the main objects of the present invention to provide a laser apparatus and method for treating cancer and other systemic diseases through the alteration of the bonding of the water molecules which represent approximately 70% of all tissue structures and the transfer of the laser energy to the different biochemical structures and stimulation of their respective electrochemical pumps.
It is another object of this invention to provide a laser apparatus and method for treating cancer and other systemic diseases that can be readily and uniformly applied systemically by directing the laser energy to the subject tissue at a distance through the patient's vascular-interstitial closed electric circuit (VICC).
It is yet another object of the present invention to provide such a device that is relatively inexpensive to manufacture and maintain while retaining its effectiveness.
In accordance with one aspect of the invention there is provided a method for treating cancerous tissues and other systemic diseases in humans and animals, comprising the steps of: A, evaluating the patient and the state of the progress of the disease and recording for subsequent comparison; and B.
applying an in~rared laser beam to the user, substantially ,,~
3a perpendicularly to the skin, following the closest VICC
biological circuit that passes by the area of the targeted tissue and said infrared laser beam being pulsed at a frequency that ranges from O.5 MHz to 7.5 MHz.
In accordance with another aspect of the invention there is provided an apparatus for treating cancerous tissues and other systemic diseases in humans and animals of the type that includes an oscillator circuit for generating pulses that activate an infrared laser diode generating an infrared laser radiation that is applied through the user's biological circuit and the improvement comprising the selection of the frequency of said pulses to be between O.5 MHz and 7.5 MHz with a voltage of up to 15 volts so that the generation of thermic radiation as a byproduct is kept to a minimum.
Further objects of the invention will be brought out in the following part of the specification, wherein detailed description is for the purpose of fully disclosing the invention without placing limitations thereon.
V. BRI8F DE8CRIPTION OF THE DRaWINGS
With the above and other related objects in view, the invent$on consists in the details of construction and combination of parts as will be more fully understood from the following description, when read in conjunction with the accompanying drawings in which:
-.
, ' .,, ' ~ :
20054Sl Figure 1 represents a block diagram of the apparatus for generating a pulsed laser beam to be used in the present invention.
VI. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
Referring now to figure 1, where the present invention is generally referred to with numeral 10, it can be observed that it basically includes oscillator circuit 20 which in the preferred embodiment generates a signal to frequency selector circuit 30 which includes an electronic divider that can be readily adjusted thereby reducing and shaping the signal from oscillator 20. It has been found that best results are obtained when the frequency of the signal is between 0.5 MHz and 7.5 MHz. This signal is shaped in the form of square pulses, preferably, and amplified through buffer circuit 40 to activate transistor 50. The time of application is controlled with timer circuit 80. Transistor 50 is implemented in the preferred embodiment a bipolar transistor. Transistor 50 is switched on and off with the pulses received from buffer circuit 40 driving lasing diode 60. Lasing diode 60 is preferably implemented with a single heteroiunction stacked diode, such as the one manufactured by Laser Diodej Inc.
(Brunswick, N. Jersey) under part number LD-160, which has a peak wavelength of emission at 904 nanometers. The resulting laser beam is then passed through an ultraviolet fil~er 70 that blocks out higher harmonics, including potentially harmful ultraviclet components. It is important to note from the manufacturer specifications that laser diodes are typically driven at lKHz pulse frequencies and that they become con8ide~ably inefficient as the frequency is increased. At 0.5 MHz the efficiency is very low and this is not a range of operation recommended by the manufacturer. This inventor, however, is not interested in efficiency of the component but rather in radiating infrared laser energy that when 200~;451 modulated with relatively high frequency pulses (0.5 MHz to 7.5 MHz equivalent to those in the ultrasonic range) stimulates the natural physiological cell function.
In practice, the method for using the apparatus described above involves the positioning of the laser beam substantially perpendicularly over the patient's skin in the closest proximity of the most direct and efficient biological circuit in accordance with the concepts of VICC described in the above referenced article of Dr. Northerstrom ~which is hereby incorporated by reference., It is well known that approximately 7~% of the body weight of human and animal tissues are composed of water. It is also well established that water is inherently a good receptor for infrared radiations, including the pristine laser infrared wavelengths. By channeling the pulsed infrared laser energy produced by the above referenced apparatus through the VICC circuit of the patient to target tissues, electronic macromolecular bonding of the water is altered along the path and at the tissues. The transfer of energy accomplished with the present method is substantially more effective than the transfer studied by Dr. Anthony S-Y Leong with the microwave radiations since the latter has a larger thermic (and destructive) component that cannot be effectively utilized to stimulate the natural repair mechanisms residing on each cell. Dr. Leong was primarily concerned with the rapid fixation of tissues for biopsy. The natural repair mechanisms include calcium pumps, hydrogen pumps, cATP ( system for high energy vinculated to phosphate) etc., when stimulated by the laser cnergy transferred, increase their opposition to the anarchical dispositions of the molecular structures of cancerous cells or other cellular dysfunctions.
20054S~
In practice, the inventor's initial basic investigation involved the evaluation of severe lesions induced by hea~ on the skin of rats. In the experiment, seven groups o~ rats were created; In groups one through six, each rat was applied a 150 degrees centigrade soldering tip for approximately 1 minute. In group 1, the rats were applied an infrared laser beam pulsed at 3.0 MHz on the lesion immediately after burning. Then a specimen of the skin was obtained and the rats sacrificed. In group 2, the laser beam was applied immediately upon the infliction of the burn and 24 hours afterwards. The skin specimen was then taken. In group 3, the laser beam was applied immediately after the burn, 24 hours after and then again 48 hours after the infliction of the lesion. Then the skin sample was taken. Groups 4 through 6 were similar to groups 1 through 3, except that the laser radiation was not applied. Finally, group 7 was the control group and nothing was done to the rats of this group. The skin samples were measured by pulsed nuclear magnetic resonance methods and the water structure was found to be progressively better (closer to healthy) structured in the groups that were most exposed to the laser radiation. The percent of error (the value of p) found in this experiment was less than 0.54%. This is clear evidence of the certainty of the experiment supporting the foregoing deduction.
After this animal experiment, a pilot experimental project was initiated in Venezuela with 16 terminal patients with at least 12 weeks of expected lifetime. The patients had different carcinoma and sarcomas. The patients were examined every S-8 weeks using magnetic resonance imaging methods to monitor the progress of the treatment. Additionally, laborator$~ routines, tumor markers and occasionally radiological procedures were utilized. All patients received the abovementioned pulsed infrared laser radiation at 3.0 MHz through the most effective VICC circuit Z00~4~1 for their particular case. These patients received multiple daily doses for periods of not less than 4 months and some of them for up to 11 months. It was observed that the tumoral activity was progressively reduced by itS
periodic monitoring through the abovementioned MRI methods. More recently, through serialized biopsy of the tumoral areas. The latter confirmed the changes announced by the MRI results. These results unequivocally establish a correlation between the application of the above referenced laser energy to the target tissues and the stimulation of the natural healing mechanisms of the body with the consequent involution Gf the tumor.
It is believed the foregoing description conveys the best understanding of the objects and advantages of the present invention.
Different embodiments may be made of the inventive concept of this invention. It is to be understood that all matter disclosed herein is to be interpreted merely as illustrative, and not in a limiting sense.
VII. INDUSTRIAL APPLICABILITY.
It is apparent from the previous paragraphs that an improvement of the type for such a laser apparatus and method is quite desirable for treating cancer and other systemic diseases through the alteration of the bonding of the water molecules which represent approximately 70% of all tissue structures and the transfer ,of the laser energy to the different biochemical structures and stimulation of their respective electrochemical pumps.
II. TECHNICAL FIELD
The present invention relates to laser devices, and more particularly, to such devices that are used to treat cancer and other systemic diseases.
III. BACKGROUND ART.
Applicant believes that the closest reference corresponds to U.S.
patent No. 4,724,835 issued to Liss et al on February 16, 1988. However, it differs from the present invention because this patented device includes a circuit that operates the infrared laser diode at a relatively high voltage with low pulse frequency. Also, while acknowledging or suggesting that ~he rise and/or fall time of the pulse may have an effect on the therapeutic effect of the above referenced patented device, it nevertheless lacks any mechanism (electronic or otherwise) to optimize this parameter. In fact, the patentees acknowledge their lack of precise knowledge for the results obtained. Finally, in Liss' patent, the laser beam is applied specifically on the injury area with the consequent inadequacy for uniform trea~ment of systemic illnesses at a distance.
Other patents describing therapeutic devices that utilize the laser technology concentrate on the cutting and burning characteristics of these beams at their different wavelengths which are not the subject of the prc8cnt invention, None of these patents suggest the novel features of the prcscnt invention.
ZOOS~Sl Another related reference is the article written by Dr. Bjorn E.W.
Northerstrom entitled "Biokinetic Impacts on Structure and Imaging of the Lung: The Concept of Biologically Closed Electric Circuits" and published in the September, 1985 issue of the American 30urnal of the Roentgen Ray Society. In this article, the concept of the Vascular-Interstitial Closed Circuit (VICC) is described. The VICC concept explains the different voltage potential drops observed by Dr. Northerstrom in the different tissues studied with direct electric current. This circuit comprises the entire circulatory system and through which the relatively low electric resistance of the plasma allows the flow of ~he direct current.
Another relevant reference in the related art includes the chapter authorèd by Dr. Anthony S-Y Leong entitled Microwave Irradiation in Histopathology in the volume 23, of part 2, of the Pathology Annual published Appleton & Lange, Norwalk, CN. In particular, on the last paragraph of page 214 the author acknowledges the effect of field-induced alterations in macromolecular hydrogen bonding, proton tunnelling and disruption of bound water may induce alterations in biologic systems. This article, however, relates only to microwave fields.
For studies relating to lower frequency (ultra-sound on fractures) treatments, the closest reference known by Applicant corresponds to the article authored by A.A. Pilla et al in the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. (IEEE Cat. No. 88CH2566-8), New Orleans, LA 1988.
IV. S~ RY OF ~HE INVENTION
It is one of the main objects of the present invention to provide a laser apparatus and method for treating cancer and other systemic diseases through the alteration of the bonding of the water molecules which represent approximately 70% of all tissue structures and the transfer of the laser energy to the different biochemical structures and stimulation of their respective electrochemical pumps.
It is another object of this invention to provide a laser apparatus and method for treating cancer and other systemic diseases that can be readily and uniformly applied systemically by directing the laser energy to the subject tissue at a distance through the patient's vascular-interstitial closed electric circuit (VICC).
It is yet another object of the present invention to provide such a device that is relatively inexpensive to manufacture and maintain while retaining its effectiveness.
In accordance with one aspect of the invention there is provided a method for treating cancerous tissues and other systemic diseases in humans and animals, comprising the steps of: A, evaluating the patient and the state of the progress of the disease and recording for subsequent comparison; and B.
applying an in~rared laser beam to the user, substantially ,,~
3a perpendicularly to the skin, following the closest VICC
biological circuit that passes by the area of the targeted tissue and said infrared laser beam being pulsed at a frequency that ranges from O.5 MHz to 7.5 MHz.
In accordance with another aspect of the invention there is provided an apparatus for treating cancerous tissues and other systemic diseases in humans and animals of the type that includes an oscillator circuit for generating pulses that activate an infrared laser diode generating an infrared laser radiation that is applied through the user's biological circuit and the improvement comprising the selection of the frequency of said pulses to be between O.5 MHz and 7.5 MHz with a voltage of up to 15 volts so that the generation of thermic radiation as a byproduct is kept to a minimum.
Further objects of the invention will be brought out in the following part of the specification, wherein detailed description is for the purpose of fully disclosing the invention without placing limitations thereon.
V. BRI8F DE8CRIPTION OF THE DRaWINGS
With the above and other related objects in view, the invent$on consists in the details of construction and combination of parts as will be more fully understood from the following description, when read in conjunction with the accompanying drawings in which:
-.
, ' .,, ' ~ :
20054Sl Figure 1 represents a block diagram of the apparatus for generating a pulsed laser beam to be used in the present invention.
VI. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
Referring now to figure 1, where the present invention is generally referred to with numeral 10, it can be observed that it basically includes oscillator circuit 20 which in the preferred embodiment generates a signal to frequency selector circuit 30 which includes an electronic divider that can be readily adjusted thereby reducing and shaping the signal from oscillator 20. It has been found that best results are obtained when the frequency of the signal is between 0.5 MHz and 7.5 MHz. This signal is shaped in the form of square pulses, preferably, and amplified through buffer circuit 40 to activate transistor 50. The time of application is controlled with timer circuit 80. Transistor 50 is implemented in the preferred embodiment a bipolar transistor. Transistor 50 is switched on and off with the pulses received from buffer circuit 40 driving lasing diode 60. Lasing diode 60 is preferably implemented with a single heteroiunction stacked diode, such as the one manufactured by Laser Diodej Inc.
(Brunswick, N. Jersey) under part number LD-160, which has a peak wavelength of emission at 904 nanometers. The resulting laser beam is then passed through an ultraviolet fil~er 70 that blocks out higher harmonics, including potentially harmful ultraviclet components. It is important to note from the manufacturer specifications that laser diodes are typically driven at lKHz pulse frequencies and that they become con8ide~ably inefficient as the frequency is increased. At 0.5 MHz the efficiency is very low and this is not a range of operation recommended by the manufacturer. This inventor, however, is not interested in efficiency of the component but rather in radiating infrared laser energy that when 200~;451 modulated with relatively high frequency pulses (0.5 MHz to 7.5 MHz equivalent to those in the ultrasonic range) stimulates the natural physiological cell function.
In practice, the method for using the apparatus described above involves the positioning of the laser beam substantially perpendicularly over the patient's skin in the closest proximity of the most direct and efficient biological circuit in accordance with the concepts of VICC described in the above referenced article of Dr. Northerstrom ~which is hereby incorporated by reference., It is well known that approximately 7~% of the body weight of human and animal tissues are composed of water. It is also well established that water is inherently a good receptor for infrared radiations, including the pristine laser infrared wavelengths. By channeling the pulsed infrared laser energy produced by the above referenced apparatus through the VICC circuit of the patient to target tissues, electronic macromolecular bonding of the water is altered along the path and at the tissues. The transfer of energy accomplished with the present method is substantially more effective than the transfer studied by Dr. Anthony S-Y Leong with the microwave radiations since the latter has a larger thermic (and destructive) component that cannot be effectively utilized to stimulate the natural repair mechanisms residing on each cell. Dr. Leong was primarily concerned with the rapid fixation of tissues for biopsy. The natural repair mechanisms include calcium pumps, hydrogen pumps, cATP ( system for high energy vinculated to phosphate) etc., when stimulated by the laser cnergy transferred, increase their opposition to the anarchical dispositions of the molecular structures of cancerous cells or other cellular dysfunctions.
20054S~
In practice, the inventor's initial basic investigation involved the evaluation of severe lesions induced by hea~ on the skin of rats. In the experiment, seven groups o~ rats were created; In groups one through six, each rat was applied a 150 degrees centigrade soldering tip for approximately 1 minute. In group 1, the rats were applied an infrared laser beam pulsed at 3.0 MHz on the lesion immediately after burning. Then a specimen of the skin was obtained and the rats sacrificed. In group 2, the laser beam was applied immediately upon the infliction of the burn and 24 hours afterwards. The skin specimen was then taken. In group 3, the laser beam was applied immediately after the burn, 24 hours after and then again 48 hours after the infliction of the lesion. Then the skin sample was taken. Groups 4 through 6 were similar to groups 1 through 3, except that the laser radiation was not applied. Finally, group 7 was the control group and nothing was done to the rats of this group. The skin samples were measured by pulsed nuclear magnetic resonance methods and the water structure was found to be progressively better (closer to healthy) structured in the groups that were most exposed to the laser radiation. The percent of error (the value of p) found in this experiment was less than 0.54%. This is clear evidence of the certainty of the experiment supporting the foregoing deduction.
After this animal experiment, a pilot experimental project was initiated in Venezuela with 16 terminal patients with at least 12 weeks of expected lifetime. The patients had different carcinoma and sarcomas. The patients were examined every S-8 weeks using magnetic resonance imaging methods to monitor the progress of the treatment. Additionally, laborator$~ routines, tumor markers and occasionally radiological procedures were utilized. All patients received the abovementioned pulsed infrared laser radiation at 3.0 MHz through the most effective VICC circuit Z00~4~1 for their particular case. These patients received multiple daily doses for periods of not less than 4 months and some of them for up to 11 months. It was observed that the tumoral activity was progressively reduced by itS
periodic monitoring through the abovementioned MRI methods. More recently, through serialized biopsy of the tumoral areas. The latter confirmed the changes announced by the MRI results. These results unequivocally establish a correlation between the application of the above referenced laser energy to the target tissues and the stimulation of the natural healing mechanisms of the body with the consequent involution Gf the tumor.
It is believed the foregoing description conveys the best understanding of the objects and advantages of the present invention.
Different embodiments may be made of the inventive concept of this invention. It is to be understood that all matter disclosed herein is to be interpreted merely as illustrative, and not in a limiting sense.
VII. INDUSTRIAL APPLICABILITY.
It is apparent from the previous paragraphs that an improvement of the type for such a laser apparatus and method is quite desirable for treating cancer and other systemic diseases through the alteration of the bonding of the water molecules which represent approximately 70% of all tissue structures and the transfer ,of the laser energy to the different biochemical structures and stimulation of their respective electrochemical pumps.
Claims (11)
1. A method for treating cancerous tissues and other systemic diseases in humans and animals, comprising the steps of:
A. evaluating the patient and the state of the progress of the disease and recording for subsequent comparison; and B. applying an infrared laser beam to the user, substantially perpendicularly to the skin, following the closest VICC biological circuit that passes by the area of the targeted tissue and said infrared laser beam being pulsed at a frequency that ranges from 0.5 MHz to 7.5 MHz.
A. evaluating the patient and the state of the progress of the disease and recording for subsequent comparison; and B. applying an infrared laser beam to the user, substantially perpendicularly to the skin, following the closest VICC biological circuit that passes by the area of the targeted tissue and said infrared laser beam being pulsed at a frequency that ranges from 0.5 MHz to 7.5 MHz.
2. The method set forth in claim 1 wherein said infrared laser beam is filtered so that any non-infrared radiations are excluded.
3. The method set forth in claim 2 wherein the pulses of said infrared laser beam have a square shape.
4. The method set forth in claim 3 wherein the voltage of said pulses is kept below 15 volts so that the thermic radiation is kept to a minimum.
5. An apparatus for treating cancerous tissues and other systemic diseases in humans and animals of the type that includes an oscillator circuit for generating pulses that activate an infrared laser diode generating an infrared laser radiation that is applied through the user's biological circuit and the improvement comprising the selection of the frequency of said pulses to be between 0.5 MHz and 7.5 MHz with a voltage of up to 15 volts so that the generation of thermic radiation as a byproduct is kept to a minimum.
6. The apparatus set forth in claim 5 further including filter means for limiting the application to a user of non-infrared radiation.
7. The apparatus set forth in claim 6 further including programmable timing means for pre-setting times of application.
8. The apparatus set forth in claim 6 wherein said pulses have a square shape and the width is between 100 nanoseconds and 200 nanoseconds.
9. The apparatus set forth in claim 7 wherein said infrared laser radiation has its peak wavelength of emission at 904 nanometers.
10. The method set forth in claim 1 wherein the pulses in said laser beam are square and have a width between 100 nanoseconds and 200 nanoseconds.
11. The method set forth in claim 10 wherein the peak wavelength of said laser beam is 904 nanometers.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002005451A CA2005451A1 (en) | 1989-12-13 | 1989-12-13 | Laser therapeutic apparatus and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002005451A CA2005451A1 (en) | 1989-12-13 | 1989-12-13 | Laser therapeutic apparatus and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2005451A1 true CA2005451A1 (en) | 1991-06-13 |
Family
ID=4143794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002005451A Abandoned CA2005451A1 (en) | 1989-12-13 | 1989-12-13 | Laser therapeutic apparatus and method |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2005451A1 (en) |
-
1989
- 1989-12-13 CA CA002005451A patent/CA2005451A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |