CA1341051C - Antagonistes du crf - Google Patents

Antagonistes du crf

Info

Publication number
CA1341051C
CA1341051C CA000611947A CA611947A CA1341051C CA 1341051 C CA1341051 C CA 1341051C CA 000611947 A CA000611947 A CA 000611947A CA 611947 A CA611947 A CA 611947A CA 1341051 C CA1341051 C CA 1341051C
Authority
CA
Canada
Prior art keywords
leu
glu
ala
arg
gln
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000611947A
Other languages
English (en)
Inventor
Jean Edouard Frederic Rivier
Wylie Walker Vale, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Application granted granted Critical
Publication of CA1341051C publication Critical patent/CA1341051C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA000611947A 1988-09-23 1989-09-19 Antagonistes du crf Expired - Fee Related CA1341051C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24891788A 1988-09-23 1988-09-23
US248,917 1988-09-23

Publications (1)

Publication Number Publication Date
CA1341051C true CA1341051C (fr) 2000-07-11

Family

ID=22941249

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000611947A Expired - Fee Related CA1341051C (fr) 1988-09-23 1989-09-19 Antagonistes du crf

Country Status (5)

Country Link
EP (1) EP0435948A4 (fr)
JP (1) JPH04501259A (fr)
AU (1) AU4428389A (fr)
CA (1) CA1341051C (fr)
WO (1) WO1990003392A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5245009A (en) * 1990-03-23 1993-09-14 The Salk Institute For Biological Studies CRF antagonists
US5235036A (en) * 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
EP0521963B1 (fr) * 1990-03-23 1998-08-12 The Salk Institute For Biological Studies Analogues de crf
US6039956A (en) * 1994-09-12 2000-03-21 Pennsylvania, Trustees Of The University Of, The Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder
EP0781140A4 (fr) * 1994-09-12 1999-11-03 Univ Pennsylvania Facteur inhibiteur de liberation de la corticotropine et procedes d'utilisation
US6323312B1 (en) 1994-12-12 2001-11-27 The Salk Institute For Biological Studies Cyclic CRF antagonist peptides
US5777073A (en) * 1994-12-12 1998-07-07 The Salk Institute For Biological Studies Cyclic CRF antagonist peptides
US6214797B1 (en) 1995-06-13 2001-04-10 The Salk Institute For Biological Studies Urocortin peptides, nucleic acid encoding same methods for using same
CA2223792A1 (fr) * 1995-06-13 1997-01-03 The Salk Institute For Biological Studies Peptides d'urocortine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75679B (fr) * 1981-06-08 1984-08-02 Salk Inst For Biological Studi
US4415558A (en) * 1981-06-08 1983-11-15 The Salk Institute For Biological Studies CRF And analogs
US4489163A (en) * 1983-04-14 1984-12-18 The Salk Institute For Biological Studies rCRF and analogs
EP0153845B1 (fr) * 1984-02-23 1993-04-21 The Salk Institute For Biological Studies Analogues de CRF

Also Published As

Publication number Publication date
WO1990003392A1 (fr) 1990-04-05
EP0435948A4 (en) 1991-11-13
EP0435948A1 (fr) 1991-07-10
AU4428389A (en) 1990-04-18
JPH04501259A (ja) 1992-03-05

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Legal Events

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