CA1259974A - Automatic centrifugal balancing mechanism - Google Patents

Automatic centrifugal balancing mechanism

Info

Publication number
CA1259974A
CA1259974A CA000503936A CA503936A CA1259974A CA 1259974 A CA1259974 A CA 1259974A CA 000503936 A CA000503936 A CA 000503936A CA 503936 A CA503936 A CA 503936A CA 1259974 A CA1259974 A CA 1259974A
Authority
CA
Canada
Prior art keywords
plate member
holding means
counterweight
axis
centrifugal force
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000503936A
Other languages
French (fr)
Inventor
James T. Holen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of CA1259974A publication Critical patent/CA1259974A/en
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B9/00Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/14Balancing rotary bowls ; Schrappers

Landscapes

  • Centrifugal Separators (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

ABSTRACT OF THE DISCLOSURE
Apparatus for generating centrifugal forces, preferably used in carrying out chemical testing, which includes counterweight means on a rotating member of the apparatus which are displaced in response to centrifugal force when no article to be subjected to centrifugal force is used with the apparatus, thereby to automatically balance the rotating member.

Description

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BACKGROUND OF THE INVENTION

Technical F'ield -This invention relates to apparatus for chemical -testing, and more specifically to an automatic balancing mechanism for use with centrifuge apparatus used in such chemical testing.

Background Art In copending Canadian Patent Application Serial Nos. 480,653, 480,654 and 480,657, filed May 2, 1985, chemical testing appara-tus in -the form of a centrifuge is disclosed. Such apparatus, as described in such copending applications, the disclosures of which are incorporated herein by reference, is particularly suitable for use in carrying out chemical testing procedures on various biological fluids, such as blood, serum, urine, spinal and amniotic fluids, and the like. As described in those copending applications, the centrifuge apparatus includes a plate member adapted to rotate at high speeds about an axis on which there is mounted one or more holding member(s) capable of receiving a sample processor card which rotates with the plate member.
The holding member is adapted to receive a sample processor card; the card defines a series of channels and/or chambers through which liquid undergoing testing can be moved under the influence of centrifugal force.
In the preferred embodiments of the aforementioned centrifuge appara-tus, the holding member is itself mounted for rotation relative to the plate member so that -the direction of centrifugal force exer-ted on the sample processor card can be changed to control the flow of liquids therethrough, thereby to effect transfer and ultimate mixing of liquids from one chamber in the processor card to another.

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In the inventions described in the aforementioned copending applications, the sample processor card can be provided with a reagent ~or mixing with, for example, a blood sample, and the mixing is effected by means of centrifugal force. Accordingly, when the disclosed chemical testing apparatu.s is in operation, the centrifugal force can release the reagent, separate solid part:iculate matter from the fluid of the blood, measure both the reagent and the blood fluid, mix them together, and finally, transport them to a chamber from which the product of the chemical testing can be measured, for example by optical means, to determine the results of the test. Generally, such results will be an indication of the presence or amount of a particular analyte of interest in the sample.
In the preferred centrifugal apparatus described in the foregoing copending applications, the plate member is usually provided with two or more holding members adapted to receive a sample processor card. Since the position and weight of the holding members with sample processor cards mounted thereon is substantially the same, two sample processor cards can be mounted symmetrically relative to the axis of rotation of the plate member to balance the latter during rotation. In some instances, however, the number of sample processor cards which are physically positioned in the holding members mounted on the rotatable plate member do not distribute the weight symmetrically relative to the axis of rotation, thereby resulting in imbalance of the rotating plate member.
There is accordingly a need to provide means to automatically balance the plate member so that, whether a sample processor card is present in each holding member or not, a substantially uniform balance in the rotatable plate member is nonetheless achieved.

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SUMMARY OF THE_INV_ENTION
The concepts of the present invention reside in apparatus for generating centrifugal forces, and preferably include a plate member adapted to rotate at high speeds about an axis on which there is mounted, radially of the axis, a holcling means. ~he holding means is mounted on the plate member ~or rotation therewith, and, when the holcling means are more than one in number, are preferably positioned symmetrically in relation to the axis of rotation of the plate member.
As described in the foregoing copending applications, the holding means is adapted to receive an article to be subjected to centrifugal ~orce. The article is, preferably, a sample processor card which defines a series of channels and/or chambers through which liquid undergoing testing can be moved under the influence of centrifugal force.
The automatic balancing mechanism o~ the present invention, which upon such centrifugal apparatus as aforedescribed, includes at least one counterweight means positioned on the plate member between the holding means and the axis of rotation of the plate member.
Also positioned on the plate member is a trigger means adjacent to the holding means and adapted to engage the article to be subjected to centri~ugal force. Thus, when such an article is positioned in the holding means, the trigger means engages the counterweight means and prevents displacement by centrifugal force of the counterweight means. On the other hand, when no such article is positioned in the holding means, the trigger means does not enyage the counterweight means, and thus centrifugal force, when the plate member is rotated about its axis, displaces the counterweight means toward the holding means, thereby to counterbalance the holding means not containing the article.
It has been found, in accordance with preferred embodiments of the invention, that a sample processor card positioned in the holding means can be counterbalanced by the counterweight means when no corresponding sample processor card is positioned in an~
other holding means on the plate member. BecaUse this automatic balancing feature is virtually self-activating without the need for a separate actuation, apart from positioning or not positioning a sample processor card in the holding means, the user of the centrifugal apparatus is assured that it will be balanced even when it is used with an odd number of sample processor cards.
It is accordingly an object of the present invention to provide an automatically-acting balance mechanism for balancing centrifuges of the type afore-described.
It is a more specific object of the inventlon to provide such an automatic ba~ancing mechanism for centrifuges in which that mechanism automatically balances the rotating plate member of the centrifuge when no sample processor card is present in a given holding member.
These and other objects and attendant advantages of the invention will appear more fully hereinafter from the detailed description which follows. For purposes of illustration, but not of limitation, preferred embodiments of the invention are shown and described with reference to the accompanying drawings.

BRIEF DESCRIPTION OF T~E DRAWINGS
Figure 1 is a top view in elevation of a schematic diagram of centrifugal apparatus embodying the automatic balancing concepts of the present invention;

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Figure 2 is a side-elevational view in cross-section, and partially broken away to show details of construction, of the apparatus shown in Figure 1, taken generally along the line 2-2 thereof;
Figure 3 is a partially schematic view of a portin of the apparatus shown in Figure 1, and showing a portion o~ the centrifugal apparatus in an initial operational (rotational) condition; and Figure ~ is a view similar to Figure 3 but showing the portion of the apparatus in a fully rotational operational condition.

DETAILED DESCRIPTION OF THE_INVENTION
Referring now in more detail to the drawings, Figures 1 and 2 illustrate preferred centrifugal apparatus embodying the concepts of the invention. The centrifuge generally shown includes a plate member 10 which is mounted for rotation about an axis 12. The plate member 10 is preferably driven by a suitable drive means 14, which may be, for example, an electric motor operating at high speeds. While plate member 10 is illustrated in FigUre 1 as a circular plate, it will be understood that its configuration is not critical to the practice of the invention. For example, it is equally possible to employ a centrifugal arm mounted for rotation about an axis.
Mounted on plate member 10 is at least one sarnple processor card holding means 16 (although in the preferred embodiment shown, two holding means 16 are illustrated). The holding means 16 is adapted to receive a sample processor card, as described more fully in the foregoing copending applications~ As is described in such copending applications, the card holder 16 is preferably in the nature of a tray and is rotatably mounted relative to the plate member 10 on an 7L~

axis 18, specifically connected to mean.s 20 (Figure 2) to rotate the card holder 16. Since the particular means 20 to rotate the holding means 16 forms no part of the present invention, the details thereof have been omitted from the drawings for the sake of simplicity.
While the axis of rotation 12 of the plate member 10 is illustrated in Figure 2 as being vertical, it will be understood by those skilled in the art that the orientation of the axis 12 is not critical to the practice of the invention. Accordingly, the axis of rotation of the plate member 10, while preferably vertical, can also be horiæontal, or inclined in any direction, since the effects of gravity on the sample processor card rotating with the plate rnember 10 are negligible.
In the preferred practice of the invent.ion, the card holder 16 can be rotated or indexed relative to the plate member 10 by the means 20. In an especially preferred embodiment, the holding means 16 can be rotated or indexed substantially 90 relative to the plate member 10. However, as will be appreciated by those skilled in the art, the holding means 16 can be rotatable by an amount greater than 90, up to and including a full 360. The important feature is that the card holder 16 be adapted to receive the sample processor card which is rotated relative to the plate member 10 so that the direction of the centrifugal force acting on the sample processor card can be altered to effect the necessary fluid-transport functions during the chemical testing operation.
For ease of description, shown in Figures 1 and
2 are a pair of holding means 16 mounted symmetrically with respect to the axis of rotation 12 of the plate member 10. As will be appreciated by those skilled in the art, it is equally possible, and sometimes preferred, to equip the plate member 10 with only one or a greater number than two, of holding means 16 which can be, and preferably are, symmetrically spaced about the plate member 10.
The automatic balancing device of the present invention includes a pair of counterweights 22 and 22' which are capable of displacement along a radius of the axis of rotation 12 of the plate member 10 toward and away from the holding means :L6. Each of the counterweights 22 and 22' is spring-biased by means of spring means 24 and 24', whereby the counterweight can be maintained in a stored position, illustrated by reference to the counterweight 22' in Figure 1.
Positioned adjacent to the holding means 16 is a trigger means 26, pivotally mounted about a pivot point 28. The trigger means 26 has a portion 30 adapted to engage a corresponding engagement means 32 of the counterweight 22. The trigger means includes a cam surface 34 which is adapted to engage a lateral surface 36 of a sample processor card 38, when the latter is positioned in the holding means 16.
Considering the right-hand holding means 16 in ~igure 1, a sample processor card 38, placed in the holding means 16, serves to pivot the trigger means 26' against the effect of a spring 40', so that the engaging portiGn 30' of the trigger means 26' engages the corresponding engaging means 32' of the counterweight 22'. ~hus, as the plate member 10 is rotated, the counterweight 22' is prevented, by the engagement of the trigger means 26' with the counterweight 22', from being displaced toward the holding means 16.
~ hen no sample processor card is positioned in the holding means 16~ as shown in the left-hand side of ~igure 1, the trigger means 26 is biased by means of spring 40 away from engagement with the counterweight means 22. Thus, as the plate member 10 is rotated, the counterweight 22 is displaced against the action of the spring 24 toward the left-hand holding means 16 shown in Figure 1. The displacement of the counterweight 22 away from the axis of rotation 12 of the plate member 10, as is appreciated by those skilled in the art, serves to counterbalance absence of the weight of the sample processor card 38 in the left--hand holding means 16.
Thus, a sample processor card 38, by means of the trigger means 26', causes the counterweight 22' to remain in the stored position because of its presence, while the absence of a sample processor card in the left-hand holding means 16 allows the counterweight 22 to be displaced away from the axis of rotation 12 of the plate member 10 to a balancing position, thereby to offset and counterbalance the absence of the sample processor card in the left-hand holding means 16 of Figure 1.
It will be well understood by those skilled in the art that other confiyurations and arrangements of the counterweight with respect to the sample processor card holding means are possible. For example, it is possible to employ one counterbalance system for each of a plurality of pairs of sample processor card holding means 16 upon the plate member 10. In that way, a sample processor card would always be provided to the holding means 16 not equipped with the automatic balancing device, while the opposite holding means 16 would be provided with an automatic balancing mechanism to counterbalance the sample processor card when no sample processor card is used in such opposite holding means 16.
Referring now to Figures 3 and 4 of the drawings for a further explanation of the operation of a centrifuge incorporating the concepts of the present 7~

g invention, in a preferred embodiment thereof, an enlarged view o~ the counterweight 22 ~ t trigger means 261 and sample processor card 38 of Figures 1 and 2 is shown. In operation of the centrifuge and concommitant rotation of the plate member 10, as previously described, initial engagement of the trigger means 26 with the counterweight 22~ is shown in Figure 3. In such initial engagement, a gap 42 exists between an upper edge 32a of the engagement means 321 of the counterweight 22 ~; and portion 30' of the trigger means 261; the gap 42 is present at the beginning of rotation of the plate member 10 when the centrifuge is initially placed in operation, as is the case when/ for e~ample, assays or chemical tests are being performed using the centrifuge. At this point in operation, the trigger means 261 is in contact with the card 38 along its cam surface 341. However, as shown in ~igure 4~ as the plate member 10 rotationally accelerates, the weight of the counterweight 221 bearing against the trigger means 261 further rotates the latter so that the gap 42 closes and the portion 301 of the trigger means 26~ contacts the upper edge 32" of the engagement means 321 ~ The trigger means 261 therefore is no longer in contact along its cam surface 341 with the card 38. ThUS, the card 38 can rotate freely relative to the plate member 10 without being hindered by the action of trigger means 261 ~
It will be understood that various changes and modifications can be made in the specific details of construction, procedure and use of the invention as described herein, without departing from the spirit and scope of the invention, which is defined solely in the following claims.

Claims (10)

The embodiments of the invention in which an exclusive property or privilege is claimed, are defined as follows:
1. In an apparatus for generating centrifugal forces including a plate member adapted to rotate about an axis and holding means mounted on the plate member in rotation therewith, said holding means being positioned on the plate member radially of the axis of rotation of the plate member and being adapted to receive an article to be subjected to centrifugal force, the improvement comprising:
(a) at least one counterweight means positioned on the plate member between said holding means and the axis of rotation of the plate member, said counterweight means having means to releasably engage a trigger means, and (b) trigger means positioned adjacent to said holding means and adapted to engage an article to be subjected to centrifugal force when such article is positioned in said holding means, thereby to engage the counterweight means and prevent displacement by centrifugal force of the counterweight means and to allow the counterweight means to be displaced toward said holding means when no article is positioned therein, thereby to counterbalance said holding means.
2. Apparatus as defined in Claim 1, further including means for rotating the plate member about the axis.
3. Apparatus as defined in claim 1, wherein said holding means are rotatable relative to the plate member during rotation of the plate member about its axis, thereby to change the direction of the centrifugal force acting on said article.
4. Apparatus as defined in Claim 3, further including means to rotate said holding means relative to the plate member.
5. Apparatus as defined in Claim 1, wherein the trigger means is capable of being pivoted in response to the placing of the article in said holding means so that the trigger means engages said counterweight means to maintains said counterweight means in a storage position.
6. Apparatus as defined in claim 1, wherein the trigger means is biased away from engagement with said counterweight means so that the trigger means is maintained away from engagement with said counterweight means when no article is positioned in said holding means.
7. Apparatus as defined in claim 1, wherein said counterweight means is biased toward the axis of rotation of the plate member.
8. In an apparatus for carrying out chemical testing under centrifugal force, including a plate member adapted to rotate about an axis and a holding means mounted on the plate member for rotation therewith, said holding means being positioned on the plate member radially of the axis of rotation of the plate member and being adapted to receive sample processor means for carrying out chemical testing under the influence of centrifugal force, the improvement comprising:
(a) at least one counterweight means positioned on the plate member between said holding means and the axis of rotation of the plate member, the counterweight means having means to releasably engage a trigger means, and (b) trigger means positioned adjacent to said holding means and adapted to engage the sample processor means to be subjected to centrifugal force when such sample processor means is positioned in said holding means, thereby to engage the counterweight means and prevent displacement by centrifugal force of the counterweight means and to allow the counterweight means to be displaced toward said holding means when no sample processor means is positioned in said holding means, thereby to counterbalance said holding means.
9. Apparatus as defined in Claim 8 which includes means for rotating the plate member about the axis.
10. Apparatus as defined in Claim 8, wherein said holding means is rotatable relative to the plate member during rotation of the plate member about its axis, thereby to change the direction of the centrifugal force.
CA000503936A 1985-03-19 1986-03-12 Automatic centrifugal balancing mechanism Expired CA1259974A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71351585A 1985-03-19 1985-03-19
US713,515 1985-03-19

Publications (1)

Publication Number Publication Date
CA1259974A true CA1259974A (en) 1989-09-26

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ID=24866447

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000503936A Expired CA1259974A (en) 1985-03-19 1986-03-12 Automatic centrifugal balancing mechanism

Country Status (4)

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EP (1) EP0195321B1 (en)
JP (1) JPS61216758A (en)
CA (1) CA1259974A (en)
DE (1) DE3668425D1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2605104B1 (en) * 1986-09-25 1989-11-24 Kis Photo Ind DYNAMIC BALANCING DEVICE OF A CENTRIFUGAL APPARATUS
FR2605108B1 (en) * 1986-09-25 1988-11-25 Kis Photo Ind AUTOMATIC DEVICE FOR PERFORMING PARTICULARLY BIOLOGICAL AND MEDICAL ANALYZES
US4865810A (en) * 1986-09-25 1989-09-12 Kis Photo Industrie Centrifuge for performing medical analyses
US5061381A (en) * 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
JP7175609B2 (en) 2015-04-05 2022-11-21 アーテリオサイト・メディカル・システムズ・インコーポレイテッド Centrifuge balance weight with adjustable center of gravity and method of use thereof
CN112044608B (en) * 2020-10-12 2024-04-16 武汉成名仪器有限公司 Laboratory centrifuge rotor balance locking device, centrifuge rotor and centrifuge

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3834613A (en) * 1971-03-01 1974-09-10 Int Equipment Co Centrifuge rotor with sample holding means and means for balancing the same
US3762635A (en) * 1971-04-14 1973-10-02 Damon Corp Apparatus for balancing a bucket centrifuge rotor
DE3570843D1 (en) * 1984-05-03 1989-07-13 Abbott Lab Centrifuge

Also Published As

Publication number Publication date
JPS61216758A (en) 1986-09-26
DE3668425D1 (en) 1990-03-01
EP0195321A2 (en) 1986-09-24
EP0195321B1 (en) 1990-01-24
EP0195321A3 (en) 1986-12-10

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