CA1257250C - - Google Patents

Info

Publication number
CA1257250C
CA1257250C CA 480870 CA480870A CA1257250C CA 1257250 C CA1257250 C CA 1257250C CA 480870 CA480870 CA 480870 CA 480870 A CA480870 A CA 480870A CA 1257250 C CA1257250 C CA 1257250C
Authority
CA
Canada
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA 480870
Other versions
CA1245215A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000566344A priority Critical patent/CA1257250A/en
Publication of CA1245215A publication Critical patent/CA1245215A/en
Application granted granted Critical
Publication of CA1257250C publication Critical patent/CA1257250C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000480870A 1984-05-07 1985-05-06 17.beta.-(THIO SUBSTITUTE)ANDROSTENES Expired CA1245215A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000566344A CA1257250A (en) 1984-05-07 1988-05-09 17.beta.-(SUBSTITUTED THIO)ANDROSTENES

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/607,920 US4529548A (en) 1984-05-07 1984-05-07 17β-(substituted thio)androstenes
US607,920 1984-05-07

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000566344A Division CA1257250A (en) 1984-05-07 1988-05-09 17.beta.-(SUBSTITUTED THIO)ANDROSTENES

Publications (2)

Publication Number Publication Date
CA1245215A CA1245215A (en) 1988-11-22
CA1257250C true CA1257250C (nl) 1989-07-11

Family

ID=24434259

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000480870A Expired CA1245215A (en) 1984-05-07 1985-05-06 17.beta.-(THIO SUBSTITUTE)ANDROSTENES

Country Status (5)

Country Link
US (1) US4529548A (nl)
EP (1) EP0161187B1 (nl)
JP (1) JPS60239499A (nl)
CA (1) CA1245215A (nl)
DE (1) DE3569539D1 (nl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4891367A (en) * 1987-04-22 1990-01-02 Merrell Dow Pharmaceuticals Inc. 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
AU1185197A (en) * 1995-12-29 1997-07-28 Glaxo Group Limited 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio-androstane derivatives (17beta-(gamma-butyric acid lactone)-thio derivatives) for the treatment of inflammation and pharmaceutical compositions and a process for the production thereof
US5962445A (en) 1996-05-09 1999-10-05 Amrad Operations Pty Ltd. Treatment of asthma and airway diseases
AU725048B2 (en) * 1996-05-09 2000-10-05 Amrad Operations Pty. Limited Treatment of asthma and airway diseases
CA2260584C (en) * 1998-02-04 2007-07-31 Charlotte-Mecklenburg Hospital D/B/A Carolinas Medical Center Androsterone derivatives for inhibiting dna binding of ap-1 and airway smooth muscle proliferation
US6262042B1 (en) 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2999101A (en) * 1959-08-13 1961-09-05 Searle & Co 11-oxygenated 17-alkylsulfinyl- and 17-alkylsulfonylandrost-4-en-3-ones
US4094840A (en) * 1977-05-12 1978-06-13 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4091036A (en) * 1977-05-12 1978-05-23 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4133811A (en) * 1978-02-17 1979-01-09 E. R. Squibb & Sons, Inc. 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4183924A (en) * 1978-02-27 1980-01-15 Schering Corporation 17α-Chloro-17β-hydrocarbonsulfinyl-1,4-androstadienes and the corresponding 17β-hydrocarbonsulfonyl derivatives and their use as anti-acne agents
US4146538A (en) * 1978-02-27 1979-03-27 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones
US4252733A (en) * 1980-03-31 1981-02-24 E. R. Squibb & Sons, Inc. 17-Substituted sulfonyl-16,16-disubstituted androstenes
US4265815A (en) * 1980-03-31 1981-05-05 E. R. Squibb & Sons, Inc. 17-(Substituted thio)androst-4-ene[16,17,-b]-[1,4]benzodioxin-3-ones
US4361559A (en) * 1981-08-20 1982-11-30 E. R. Squibb & Sons, Inc. Antiinflammatory 17,17-bis (substituted thio) androstenes
US4397782A (en) * 1982-05-28 1983-08-09 E. R. Squibb & Sons, Inc. Antiinflammatory 17-spiroandrostenes
US4435326A (en) * 1982-09-09 1984-03-06 E. R. Squibb & Sons, Inc. Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes
US4420428A (en) * 1982-12-27 1983-12-13 E. R. Squibb & Sons, Inc. 16-Ketoandrostene-17-dithioketals
US4427592A (en) * 1983-01-31 1984-01-24 E. R. Squibb & Sons, Inc. Androstene-17-dithioketals

Also Published As

Publication number Publication date
US4529548A (en) 1985-07-16
JPS60239499A (ja) 1985-11-28
EP0161187A3 (en) 1986-08-13
DE3569539D1 (en) 1989-05-24
EP0161187B1 (en) 1989-04-19
EP0161187A2 (en) 1985-11-13
CA1245215A (en) 1988-11-22

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Legal Events

Date Code Title Description
MKEX Expiry
MKEX Expiry

Effective date: 20051122