CA1256866C - - Google Patents

Info

Publication number
CA1256866C
CA1256866C CA 478539 CA478539A CA1256866C CA 1256866 C CA1256866 C CA 1256866C CA 478539 CA478539 CA 478539 CA 478539 A CA478539 A CA 478539A CA 1256866 C CA1256866 C CA 1256866C
Authority
CA
Canada
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA 478539
Other versions
CA1247093A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000569484A priority Critical patent/CA1256866A/en
Publication of CA1247093A publication Critical patent/CA1247093A/en
Application granted granted Critical
Publication of CA1256866C publication Critical patent/CA1256866C/xx
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CA000478539A 1984-04-10 1985-04-09 N-[(AMINO)ALCOYL]-1-PYRROLIDINE, 1-PIPERIDINE AND L-HOMOPIPERIDINE-CARBOXAMIDES (AND THIOCARBOXAMIDES) WITH SULFUR-BOND SUBSTITUTION IN POSITION 2, 3 OR 4 Expired CA1247093A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000569484A CA1256866A (en) 1984-04-10 1988-06-14 N-¬(amino)alkyl| -1-pyrrolidine, 1-piperidine and 1-homopiperidine intermediates with sulfur linked substitution in the 2,3 or 4-position

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59858284A 1984-04-10 1984-04-10

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000569484A Division CA1256866A (en) 1984-04-10 1988-06-14 N-¬(amino)alkyl| -1-pyrrolidine, 1-piperidine and 1-homopiperidine intermediates with sulfur linked substitution in the 2,3 or 4-position

Publications (2)

Publication Number Publication Date
CA1247093A CA1247093A (en) 1988-12-20
CA1256866C true CA1256866C (de) 1989-07-04

Family

ID=24396141

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000478539A Expired CA1247093A (en) 1984-04-10 1985-04-09 N-[(AMINO)ALCOYL]-1-PYRROLIDINE, 1-PIPERIDINE AND L-HOMOPIPERIDINE-CARBOXAMIDES (AND THIOCARBOXAMIDES) WITH SULFUR-BOND SUBSTITUTION IN POSITION 2, 3 OR 4

Country Status (6)

Country Link
EP (1) EP0160436A3 (de)
JP (1) JPS60228454A (de)
AU (1) AU565886B2 (de)
CA (1) CA1247093A (de)
IL (1) IL74140A (de)
PH (2) PH22414A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3800868A1 (de) * 1988-01-14 1989-07-27 Thomae Gmbh Dr K Mittel zur behandlung von bradycardien und bradyarrhythmien
GB8928383D0 (en) * 1989-12-15 1990-02-21 Ici Plc Insecticidal compounds
FR2721314B1 (fr) * 1994-06-20 1996-07-19 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
BR9712792A (pt) * 1996-08-28 1999-12-14 Procter & Gamble Inibidores de metaloprotease bidentada.
PT1278728E (pt) * 2000-04-20 2004-10-29 Hoffmann La Roche Derivados de pirrolidina e de piperidina e sua utilizacao no tratamento de disturbios neurodegenerativos
US7408067B2 (en) 2002-01-17 2008-08-05 Merck + Co., Inc. Aza-cyclic compounds as modulators of acetylcholine receptors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45511B1 (en) * 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof
IL65567A (en) * 1981-05-20 1985-11-29 Robins Co Inc A H N-(arylthioalkyl)-n'-(aminoalkyl)ureas and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS60228454A (ja) 1985-11-13
PH22414A (en) 1988-08-26
AU3811685A (en) 1985-10-17
IL74140A (en) 1988-05-31
EP0160436A3 (de) 1988-06-08
IL74140A0 (en) 1985-04-30
CA1247093A (en) 1988-12-20
EP0160436A2 (de) 1985-11-06
PH22573A (en) 1988-10-17
AU565886B2 (en) 1987-10-01

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Legal Events

Date Code Title Description
MKEX Expiry