CA1237124A - Starch, gum, and cellulose derivatives containing aldehyde groups; their preparation from the corresponding acetals and use as paper additives - Google Patents

Abstract

POLYSACCHARIDE DERIVATIVES CONTAINING ALDEHYDE GROUPS, THEIR PREPARATION FROM THE CORRESPONDING ACETALS AND USE AS PAPER ADDITIVES Polysaccharide aldehydes having the general structure <IMG> Y-, such as starch, cellulose and gum aldehydes, are useful for imparting wet, dry, or temporary wet strength to paper. They are prepared by a non-oxidative method which involves reacting the polysaccharide base, in the presence of alkali, with a derivatizing acetal reagent having the general structure <IMG> and then hydrolyzing the acetal by adjusting the pH to less than 7, preferably 2-4. R is (CH2)n or a divalent aromatic group and n is 0 or greater; R1, R6, and R7 are hydrogen or an organic group; R2, R5, and R8 are (CH2)m with m being 1-6; R3 and R4 are hydrogen or a lower alkyl; Y is an anion; Z is an organic group capable of reacting with the polysaccharide base to form an ether derivative and selected from the group consiting of an epoxide, ethylenically unsaturated group, halohydrin, and halogen; R11, if present, is a divalent organic group containing no reactive substiuents; and A and A' are lower alkyls or together form at least a 5-membered cyclic acetal.

Description

~23~7~Z~L

POLYSACCHARIDE DERIVATIYES CONTAINING AlDEHYDE
GROUPS, THEIR PREPARATION FROM THE CORRESPONDING ACETALS
AND USE AS PAPER ADDITIYES

The present invention relates to polysaccharide derivatives containing aldehyde groups and to the acetal derivatives used in the preparation thereof. It also relates to a non-oxidative process for introducing aldehyde groups into polysaccharides. It further relates to the use of the cationic aldehyde-containing derivatives as paper additives.
As used herein, the term "paper" includes sheet-like rnasses and molded praducts made from fibrous cellulosic materials which may be derived from natural sources as well as from synthetics such as poly-amides, polyecters, and polyacryliç resins, and from material fibers such as asbestos and glass. In addition, papers, made from combinations of cellulosic and synthetic materials are applicable herein. Paper-board is also included within the broad term "paper".
c Oxidative and non~oxidative methods have been used to introduce aldehyde groups into polysaccharides such as starches, gums, celluloses.
The oxidative methods used have included treabment with periodic acid, periodates, or alkali metal ferrates. See U.S. Pat. No. 3,086,969 (issued April 23, 1963 to J. E. Slager) which discloses an improved process for the preparation of a dialdehyde polysaccharide, ~e.g., starch) using periodic acid; U.S. Pat. No. 3,062,652 ~lssued Nov. 6, 1962 to R. A. Jeffreys et al.) which discloses the preparation of dialdehyde gums (e.g., gum acacia, pectin, and guar) using periodate or periodic acid; and U.S. Pat. No. 3,632,802 (issued Jan. 4, 1972 to J. N.

.

7h2~

- 2 BeMiller et al.) which discloses a method for oxidizing a carbohydrate, (e.g., starch or cellulose) with an alkal; metal ferrate.
In the above methods the aldehyde groups are formed by the oxi-dation of the hydroxyl groups on the ring and/or side chain. Treatment with periodic acid or periodate selectively oxidizes the 2~3-glycol struc~ures (i.e., the adjacent secondary hydroxyl groups on the ring carbon atoms), cleaves the ring, and results in a "so-called" dial-dehyde derivative which is principally a hydrated hemialdal and intra-and intermolecular hemiacetals. Treatment of carbohydrates with alkali metal ferra~es selectively oxidizes the primary alcohol group on the side chains ~ithout ring cleavage or oxidation of the ring hydroxyls.
The disadvan~ages o~ the oxidative method include degradation to lower molecular weight products and the formation of carboxyl groups due to further oxidation of the aldehyde groups. U.S. Pat. No.

3,553,193 (issued Jan. 5, 1973 to D. H. LeRoy et al.) describes a method for oxidizing starch using an alkali metal bromite or hypo-bromite under carefully controlled conditions. The resulting dialde-hyde is reported to have a substantially greater proportion of carbonyl groups li.e., aldehyde groups) than carboxyl groups. It also discloses a method for selectively oxidizing the side chains of starch deriva-tives (e.g., an alkoxylated starch such as dihydroxypropyl starch) under the same process conditions whereby the underivatized starch hydroxy groups on the rings are substantially non-oxidized.
The presence of carboxylic groups in aldehyde starches has several disadvantages in addition to the obvious reduction in the degree of aldehyde substitution. These include the introduction of hydrophilic properties due to the carboxyl groups, an upset in the cationic/anionic 1~3'71~:~

ratio when a cationic starch base is used (as in most papermaking wet end uses), and the possible formation of salts (in the above paper-making end use) which could give rise to ionic crosslinking.
The non-oxidative methods typically involve the reaction of the polysaccharide with an aldehyde-containing reagent. See U,S. Pat. Nos.
3,5~9,618 (issued July 7, 1970 to S. M. Parmerter) and U.S. Pat. No.
3,740,391 (issued June 19, 1973 to L. L. Williams et al.) which cover starch derivatiYes and U.S. Pat. No. 2,803,558 (issued Aug. 20, 1957 to G. D. Fronmuller) which covers a gum derivative. The starch deriva-tive of Parmerter is prepared by reaction with an unsaturated aldehyde(e.g. acrolein) and has the structure Starch-O-CH(Rl)-CH(R2)-CHO where Rl and R2 are hydrogen, lower alkyls or halogen. The starch derivative of Williams is prepared by reaction with acrylamide followed by reaction O OH
Il I
with glyoxal and has the structure Starch-O-CH2-CH2-C-NH-CH-CHO. The gum derivative of Fronmuller is prepared by treating the dry gum (e.g., locust bean or guar gum) with peracetic acid to reduce the viscosity, neutrali~ing, and then reacting with glyoxal. Water-soluble cellulose ethers (e.g., hydroxyethylcellulose) have also been reacted with glyoxal or ureaformaldehyde to give aldehyde-containing derivatives.
One of the disadvantages of introducing the aldehyde groups directly using an aldehyde-containing reagent is the possibility of the deriva-tive crosslinking prior to use. This is a particular disadvantage when the products are being used to impart ~emporary wet strength to paper via a crosslinking reaction with the cellulose fibers. The Williams patent (cited above) alludes to this problem when it notes ~237~

tha~ solutions of the glyoxalated polymers "are stable for at least a week when diluted to 10~ solids by weight and adjusted to pH 3" (see Col. 3, lines 60-63). The Parmerter patent notes that the starch aldehyde is "a substantially non-crosslinked granular starch deriva-tive" and discusses the importance of the non-crosslinked character (see Col. 2, lines 40-45).
Therefore there is a need for aldehyde-containing polysaccharide derivatives and an improved non-oxldative method for their preparation which does not crosslink thP derivative.
The present inven~ion provides novel polysaccharide aldehyde deriva-O qH
tives which have the formula Sacch-O-CH2-R-C-N-R2-CHO, Sacch-O-CH-C-CHO, OH R!6 Sacch-O-CH2-CH-R5-N+-R8-CHO Y~, as well as novel polysaccharide R7 o ,OA

acetals which have the formula Sacch-O-CH2-R9-C-N-R2-C ? , or Rl `OA' OH / OA OH ~6 ,OA

Sacch-O-CH-C-CH , or Sacch-O-CH2-CH-R5-N+-R8-CH . Y~.

R3 R4 ~OA ' R7 OA' It also provides a polysaccharide aldehyde having the formula Sacch-O-R10-CHO prepared by hydrolyzing, at a pH of 7 or less, a OA

polysaccharide acetal having the formula Sacch-O-R10-CH which is \ OA' ~237~æ~L

prepared by reacting the polysaccharide, at a pH of about 9 or above, with an acetal reagent which does not substantially crosslink or oxidi~e the polysaccharide during the reaction. The reagent is described hereafter.
In the above formulas Sacch-O- represents a polysaccharide mole-cule (wherein in the hydrogen of a hydroyxl group of a saccharide unit has been replaced as shown); R is (CH2)n or a divalent aromatic group and n is zero or greater; R9 is (CH2)n or a divalent aromatic group and n is zero or greater, with the proviso that n is 1 or more when the polysaccharide molecule is a starch molecule; R1, R6 and R7 are hydrogen, an alkyl (preferably methyl), aryl, aralkyl, or alkaryl group; R2, R5 and R8 are (CH2)m with m being 1-6 (preferably 1-2);
R3 and R4 are hydrogen or a lower alkyl3 preferably methyl; R10 is a divalent organic group, containing no starch-reactive substituents; A
and A' are independently a lower alkyl or A and A' together form at least a 5-membered cyclic acetal; and Y is an anion such as a halide, sulfate, or nitrate. The polysaccharide molecule may be modified by the introduction of cationic, anionic, nonionic, amphoteric, and/or zwitterionic substituent groups. As used herein, the terms "cationic"
and "anionic" are intended to cover cationogenic and anionogenic groups and the term "reactive substituents" refers to substituents which react with polysaccharide to form a covalent bond.
The aldehydes are prepared by hydrolyzing the corresponding acetal at a pH of less than 7, preferably 5 or less, most preferably 2.U-4~0.
5 The acetals are prepared by reacting the polysaccharide with an / OA
acetal reagent having the general structure Z-R11-CH , where Z is \ OA' ~Z37~2~

an organic group capable of reacting with the saccharide molecule to form an ether derivative and selected from the group consisting of an epoxide, a halohydrin, an ethylenically unsaturated group, and a halogen and Rl1, if present, is a divalent organic group containing 5 no reactive substituents.
O OA
Typical reagents have the formula X-CH2 R9-~-N-R2-CH
R1 \ OA' O / OA ~ O / OA R3 ~4 / OA
10 CH2=CH-C-N-R2-CH , H - C---CH , HC - C-CH , or R1 `OA' R3 R4 \ OA' I 1H \ OA' H ~ -~ H_R5_N+_R8_CH , where R1 to R9 and A and A' are as l7 \ OA' defined above and X is chlorine, bromine, or iodine. In the halohydrin reagent the halogen and hydroxyl groups may be interchanged.
The aldehyde and acetal derivatives are useful in conventional appli-cations where water soluble or water swellable polysaccharide deriva-tiYeS are useful, for example, as coatings, adhesives and paper additives.
The cationic aldehyde-containing derivatives are particularly useful as paper additives. They are useful as temporary wet strength additives, for example in tissue/toweling paper stocks, and as wet and dry strength additives for all paper types including liner board. Typical cationic and cationogenic groups include the diethylaminoethyl ether groups introduced by reaction with 2-diethylaminoethylchloride hydrochloride or 3-(trimethyl ammonium chloride)-2-hydroxypropyl ether groups~intro-duced by reaction with 3-chloro-2-hydroxypropyl trimethylammonium ~1~3712~

chloride.
When the polysaccharide is starch, applicable starch bases which may be used herein may be derived from any plant source including corn, potato, sweet potato, wheat, rice, sago, tapioca, waxy maize, sorghum, high amylose corn, or the like. Starch flours may also be used as a starch source. Also included are the conversion products derived from any of the former bases including, for example, dextrins prepared by the hydrolytic action of acid and/or heat; oxidized starches prepared by treatment with oxidants such as sodium hypochlorite;
fluidity or thin-boiling starches prepared by enzyme conversion or mild acid hydrolysis; and derivatized and crosslinked starches. The starch base may be a granular starch or a gelatinized starch, i.e. non-granular starch.
When the polysaccharide is gum, applicable bases which may be used herein are polygalactomannans, which are heteropolysacchrides composed principally of long chains of 1-~4 ~ -D-mannopyranosyl units to which single unit side chains of ~ -D-galactopyranosyl units are joined by 1--~6 linkages and hereafter referred to as "gums". Also included are degraded gum products resulting from the hydrolytic action of acid, heat, shear, and/or enzyme; oxidized gums; and derivatized gums. The preferred gums include gum arabic, as well as guar gum and locust bean gum because of their commercial availability.
When the polysaccharide is cellulose, applicable ~ases useful herein include cellulose and cellulose derivatives, especially water-soluble cellulose ethers such as alkyl and hydroxyalkylcelluloses, specifically methylcellulose, hydroxypropylmethyl cellulose, hydroxybutylmethyl-- cellulose, hydroxyethylmethylcellulose, and ethylhydroxyethylcellulose.

~23~

Methods for preparing the modified polysaccharide bases are well-known to those ski11ed in the art and discussed in the literature.
See, for example, R.L. Whistler, Methods in Carbohydra~e Chemistry, Yol. IV, 1964, pp. 279-311; R.L. Whistler et al., Starch-Chemistry and Technology, Vol. II, 1967, pp. 293-430; R.L. Davidson and N. Sittig, Water-Soluble Resins, 2nd Ed., 1968, Chagter 2; and R.L. Davison, ~land-book of Water-Soluble Gums and Resins, 1980, Chapters 3, 4, 12 and 13 directed to cellulose derivatives, Chapters 6 and 14 directed to gums, and Chapter 22 directed to starch.
The starch reactions with the derivatizing reagents that introduce the acetal groups are carried out using the general procedure described in U.S. Pat. No. 3,880,832 issued April 29, 1975 to M.M. Tessler. Granu-lar reactions are typically carried out in water at 20-50C, preferably about 40-45C. Non-granular starch reactions may be carried out at higher temperatures (e~g., up to 100~C). Tne reaction mixture is pref-ferably agitated. Reaction time may vary from 0.5-2a hours, preferably 8-16 hours, for aqueous reactions or from 1-8 hours for reactions carried out in a substantially dry reaction medium. It will depend on such factors as the amount of reagent employed~ the temperature, ~he scale of the reaction, and the degree of substitution desiréd. The pH
is maintained at 10-13, preferably 11-12, during the reagent addition and during the entire reaction using a base such as sodium, potassium, or calcium hydroxide. Sodium sulfate is typically added to the reac-tion mixture to reduce swelling of the granular starch, it is not used when calcium hydroxide is the base.
Potassium or sodium iodide is a good catalyst for reacting the chloro-- acetylated amine derivatives, but it is not necessary for a satisfac-~31~2~

tory reaction with the starch. After completion of the reaction, the excess alkali is neutralized and the pH is adjusted to 7-8 using any conventional acid prior to recovery of the starch. If the final pH of the starch derivative is less than 5-6, the derivatives may crosslink with time and disperse poorly or not at all.
The gum reactions with the acetal reagents are carried out in a two-phase reaction system comprising an aqueous solution of a water-miscible solvent and the w~ter-solubl~ reagent in contact with the solid gum. The water content may vary from 10 to 60~ by weight depending upon the water-miscible solvent selected. If too much water is present in the reaction system, the gum may swell or enter into solution thereby complicating recovery and purification of the derivative. The water-misci~le solvent is added in the amount sufficient for the preparation of a slurry which can be agitated and pumped. The weight ratio of water-miscible solvent to gum may vary from 1:1 to 10:1, preferably from 1.5:1 to 5:1. Suitable water-miscible sol~ents include al~anols, glycols, cyclic and acylic alkyl ethers, alkanones, dialkyformamide and mixtures thereof. Typical solvents include methanol~ ethanol, isopropanol, secondary pentanol, ethylene glycol, acetone, methyethylketone, diethyl-ketone, tetrahydrofuran, dioxane, and dimethylformamide. The reaction times and temperatures used for the aqueous reactions are suitable for the solvent reaction.
The cellulose reactions with the acetal reagents are conveniently carried out using the procedure of U.S. Pat. No. 4,129,722 (issued Dec.
12, 1978 to C. P. Iovine et al.). The cellulose or cellulose deriva-tive is suspended in an organic solvent and a water solution oF the derivatizing reagent is added thereto. Derivatization in the resultant ..
, ~23~

two-phase mixture is ordinarily carried out with agitation at tempera~
tures of 30 to 85C., adding alkali iF necessary to effect reaction.
At least one of the initial phases (i.e., the suspended cellulose or cellulose derivative or the aqueous reagent solution) contains a suit-able surfactant. It is important that the organic solvent used in theinitial cellulose phase be immiscible with the aqueous derivatizing reagent phase, that it not dissolve the cellulose derivative as it is formed, that it have a boiling point at or above the temperature of the derivatizing reaction, that it be insensitive to alkali and not parti-cipate in the derivatization reaction.
The two phase procedure may also be used to prepare starch and gumderivatives as well as cellulose derivatives. It may also be used to prepare derivatives containing substituents derived from different reagents without isolating the substitution product from each reagent.
This multiple substitution may be accomplished by the addition of several different reagents to the substrate-surfactant alkali mixture at the same time or sequentially.
After completion of the acetal reaction the solid acetals may be separated, if desired, from the reaction mixture by centrifugation or filtration. Preferably, the derivative is purified by washing with water in the case of the starch derivatiYes, with the aqueous solution of water-miscible solvent in the case of the gum derivatives or with the solvent in the case of the cellulose derivatives. Further washing with a more anhydrous form of the same solvent may be desirable for the gum derivatives. The derivatives are then dried using conventional methods, as in a vacuum, drum, flash, belt, or spray drier.
The conversion of the polysaccharide acetals to the aldehydes is ~L23~Z~

carried out under acidic conditions, typically at a p~l of 6 or less, preferably 5 or less, most preferably at 2-3. It may be carried out directly without isolation of the acetal or the acetal may be isolat-ed as above and resuspended in water prior to conversion. If desired, the derivatives may be recovered as described above.
In addition to preparing the above aceta~s, or aldehydes, modified derivatives may be prepared which contain other substitutent groups, hydroxyalkyl groups (e.g., hydroxypropyl ether groups), carboxyalkyl ether groups (e.g., carboxymethyl), ester groups (e.g., acetate groups), tertiary amino groups ~e.g., diethylaminoethyl ether groups), and quaternary amine groups, (e.g. 3-(trimethylammonium chloride)-2-hydroxypropyl grops or 4-(trimethylammonium chloride)2-butenyl groups), introduced prior to or subsequent to reaction with the acetal derivatizing reagent or introduced simultaneously by reaction with the acetal reagent and other derivatizing reagent.
The aldehyde derivatives used as paper additives preferably con-tain cationic (e.g., such as the quaternary ammonium and teriary amine group discussed above), amphoteric, and/or zwitterionic groups.
These derivatives are dispersed in water before use. The granular starch derivatives are cooked to provide the dispersed derivative.
The starch may be cooked prior to derivatization to form the acetal, subsequent to derivatization, after conversion to the aldehyde, or most conveniently during conversion of the acetal to the aldehyde.
Cooking at pH 6 or less simultaneously converts the acetal to aldehyde and solubilizes and disperses the starch aldehyde. Any conventional cooking procedure may be used, such as cooking a slurry con~aining the water-soluble or water-swellable derivative in a boiling water bath for ~23~

about 20 minutes, blowing in steam to heat the slurry to about 93C
(200F), or jet cooking. If a water-dispersible or water-soluble starch base is used for the preparation of the acetal, it will not be necessary to cook the acetal during the acid hydrolysis.
The aldehyde derivatives described herein may be used as beater additives, although their addition to the pulp may occur at any point in the paper-making process prior to the ultimate conversion of the wet pulp into a dry web or sheet. Thus, for example, they may be added to the pulp while the latter is in the hydropulper, beater, various stock chests, or headbox. The derivatives may also be sprayed onto the wet web. If the derivative is trapped in the wet fibers after spraying, it may not be necessary to use cationic aldehyde derivatives but they are preferred.
The aldehydes herein may be effectively used for addition to pulp prepared from any type of cellulosic fibers, synthetic fibers, or combinations thereof. Among the cellulosic materials which may be used are bleached and unbleached sulfate ~Kraft) bleached and unbleached sulfite, bleached and unbleached soda, neutral sulfite, semi-chemical chemiground wood, ground wood or any combination of these fibers.
Fibers of the viscous rayon or regenerated cellulose type may also be used if desired.
Any desired inert mineral fillers may be added to the pulp which is to be modified with the aldehydes herein. Such materials include clay, titanium dioxide, talc, calcium carbonate, calcium sulfate and diatomac-ous earths. Rosin or synthetic internal size may also be present ifdesired.

The proportion of the aldehyde to be incorporated into the paper ";l L~ . ~,. * Trade Mark ~37~Z4 pulp may ~ary in accordance with the particular pulp involved and the properties desired (e.g., wet strength, temporary wet strength, or dry strength). In general, it is preferred to use 0.1-10~, preferably 0.25-5% of the derivative, based on the dry weight of the pulp.
Within this preferred range the precise amount which is used will depend upon the type of pulp being used, the specific opera~ing condi-tions, the particular end use for which the paper is intended, and the particular property to be imparted. The use of amounts greater than 5~, based on the dry weight of the pulp, is not precluded, but is ordinarily unnecessary in order to achieve the desired results.
In the examples which follow, all parts and percentages are given by weight and all temperatures are in degrees Celsius unless otherwise noted. Reagent percentages are based on dry polysaccharide. The nitrogen content of the cationic bases and resulting acetals was measured by the Kjeldahl method and are based on dry polysaccharide.
In the paper tests, the tensile strengths are reported as breaking length (m.j. The breaking 1ength is the calculated limiting length of a strip of uniform width, beyond which, if such as strip were suspended by one end, it would break of its own wei~ht. The breaking length (air dry) in meters (m.) is calculated using the formula B.L. = 102,000 T T' R = 3,658 R', where T is tensile strength in kN./m., T' i5 tensile strength in lb./in., R is grammage (air dry) in g./m.2, and R' is weight per unit area (air dry in lb./1000 ft.2). Paper specimens are selected in accordance with TAPPI T 400 sampling procedure. Those evaluated for wet strength and temporary wet strength were saturated with distilled water by immersion and/or soaking until the paper sample was thoroughly ~237~Z4 wetted. The strength was evaluated in accordance with TAPPI T 494 om-82.
The measurements were carried out using a constant rate of elongatlon apparatus, i.e. a Finch wet strength device, which is described in TAPPI
Procedure T 456 om-82 (1982). The dry strength was evaluated in accor-dance with TAPPI T 494 om-81.
Example I
This example describes the preparation of known cationic starch acetals by several methods using various starch bases. The reagents used for preparing the starch acetals have the general formula X-CH2-C-N-R2-CH , where R1 is H or -CH3, R2 is -CH2-, A and A' R1 \ OA' are - CH3 or -C2Hs, and X is Cl or Br. They are prepared by reacting a haloacetyl halide with aminoacetaldehyde diethyl acetal or methyl-aminoacetaldehyde dimethyl acetal as described below.
Acetal Reag nt Preparation Reagent A - N-(2,2-Dimethoxye~hyl)-N-methyl-2-chloracetamide, which has !l /OCH3 the formula Cl-CH2-C-N-CHz-CH , is prepared by adding chloroacetyl chloride ~29.05 9.) dropwise to a stirred mixture of methylaminoacetal-dehyde dimethyl acetal ~33.5 9.) in toluene (170 ml.) and 20~ aqueous sodium hydroxide (52.9 9.). The reaction was cooled by ;mmersion in an ice/brine bath and the addition rate was adjusted to maintain the reac-tion temperature at 0-5C. The total addition took 10 mins. at which time the cooling bath was removed. Agitation was continued for an ad-ditional 10 mins. and the phases were then separated. Excess toluene ~%37~2q~

was removed from the upper organic phase by distillation at the aspira tor to gi~e Reagent A as a brown liquid.
Reagent B - N-(2,2-Diethoxyethyl)chloroacetamide, which has the formula e ,oc2H5 Cl-CH2-C-y-cH2-cH , was prepared as above except that aminoacet-H OC2Hs aldehyde diethyl acetal (37.4 9.) was substituted for the methylamino-acetaldehyde dimethy7 acetal. The product was isolated as a yellow waxy solid.
Reagent C - N-(2,2-Dimethoxyethyl)-N-methyl-2-bromoacetamide, which has the formula Br-cH2- -1_CH2_CH , was prepared in the same way CH3 \ OCH3 as Reagent A except that bromoacetyl chloride (40.4 g.) was substituted for the chloroacetyl chloride. The product was isolated as a brown liquid.
Starch Reactions Part A. Consecutive Reactions Usin~ Cationic Reagent Followed by Acetal Rea~ent (1) A waxy maize starch (250 g.) was slurried in 375 ml. of water. To the slurry was added 2.3~ calcium hydroxide (Ca(OH)2) followed by 6.3~ of a 50~ aqueous solution of 2-diethylaminoethylchloride hydrochloride (DEC). The reaction was run at 40C. for S hrs. A 10~
aqueous hydrochloric acid solution (HCl) was added to adjust the pH to 3Ø The mixture was filtered and the solids washed. A portion of the filter cake containing 50 g. of the cationic starch ether was dried and analyzed. Cationic N was 0.28~.
The remaining filter cake (about 200 g. starch) was reslurried in ~37~

150 cc water; 80 9. of sodium sulfate (Na2S04) were added; and the pH
was raised to about 11.0-11.5 by adding a 4.5~ sodium hydroxide (NaOH) solution containing 10~ NazS04. A total of 19.0 9. (9.5~ of Reagent A was added. The slurry was placed in a bath at 45C for 16 hrs. while maintaining the pH above 11.0 with the 4.5~ NaOH solution. The pH was adjusted to about 7.0-8.0J with 10~ HCl. The resulting product was filtered, washed with water adjusted to pH 7.0-8.0, and dried. It con-tained 0.72~ total N. The nitrogen content due to the acetal substitu-ent was 0.44~.
(2) The DEC reaction was carried out as in (1) except that corn starch was used. Cationic N was 0.29~. Acetal reaction was carried out using 5~ potassium iodide (KI) as a catalyst (see U.S. Pat. No. 3,880,832 cited previously). A total of 1000 9. of the cationic corn starch was suspended in 1250 ml. of water containing 300 g. Na2S04. An aqueous solution of 40 9. NaOH, 50 9. Na2S04, and 710 9. water was added slowly to the starch slurry. Then 300 9. of Reagent B were added all at once followed by the KI. Reaction conditions were 16 hr. at 45C.
The derivative was recovered as above but, after washing, it was resus-pended in water and 5 9. sodium bisulfite was added. The slurry was ~iltered but not washed. The bisulfite salt prevents oxidation of the ~~
salts to iodine which produces a brown color. Acetal N was 0.41~.
(3) The DEC reaction was carried out on a waxy maize starch using the procedure of (1) except that 40~ Na2S04 was used to repress swel-ling and 4.5~ NaOH was used to maintain the pH at above 10.8. Cationic N was 0.232~. The acetal reaction was ~arried out as in (1) except that 11~ Reagent A (based on about 200 9. starch remaining in the slurry) was used. No Na2S04 was added. The pH was adjusted to above 10.8 with

4.5~ NaOH. Reaction conditions were 19 hr. at 40~C. Acetal N was 0.37~.

~37~LZ~

(4) The DEC and acetal reactions were carried out on a waxy maize starch using Reagent A (9.5%) and the procedure of (3) except that 12 aqueous potassium hydroxide was used to control the reaction and no Na2S04 was used. Cationic and acetal N were 0.25~ and 0.45~ respect ively.

(5) The DEC reaction was carried out on a waxy maize starch using the procedure of (3). Cationic N was 0.26~. The acetal reaction was carried out in 300 ml. of water containing 80 g. Na2S04. The pH was adjusted to 11.~-11.5 using the NaOH/Na2S04 solution of (1). Reagent A (11~) was used; the reaction conditions were 19 hr. at 30C. Acetal N was 0.40~.

(6) The DEC and acetal reactions were carried out as in (5) except at 50C. Cationic and acetal N were 0.26~ and 0.32~ respectively.
Part B. Simultaneous Reaction (1) An unmodified waxy maize starch was slurried in water and 3.15~ DEC and 12~ Reagent A were added while maintaining the pH above 11.0 with a 4.5~ NaO~ solution. The reaction mixture was maintained at 45C and pH 11.0-11.5 for 16 hr. and then neutralized to pH 7.5. The product was recovered as above. It had a total N content of 0.77~.
(2) A similar reaction was carried out using potato starch (200 9.) and 16 parts of a 50~ solution of 3-chloro-2-hydroxypropyl trimethyl ammonium chloride and 12~ Reagent A. The product contained 0.91~ total N. Cationic N was not determined (theoretical was about ~.3~ maximum).
The potato starch base contained about 0.013~ N. Acetal N should be about 0.60~.

Part C Consecutive Reaction Using Acetal Reagent Followed by _ationlc Reagent An unmodified waxy maize starch (1000 9.) was slurried in 1500 cc.

3~

water containing 400 9. Na2S04, and the pH was raised to 11.2 with a NaOH solution made by dissolving 40 9. of solid NaOH and 90 y. Na2S04 in 7709. water. The above acetal reagent A (10~ was added and the reaction was maintained at pH 11.2 and 45C for 16 hrs. The product S (recovered as above) had an acetal N content of 0.57~.
The resulting acetal (200 9.) was reacted with 16 g. of the 50%
aqueous DEC solution as described in above. The final product con-tained 0.72% total N.
Part D. Dry Reaction 200 9. of a cationic, waxy maize starch (0.26~ nitrogen) made as in Part A - No. 3 were impregnated in a Hobart mixer with a solution consisting of 24 g. acetal reagent A, 2.5 9. NaOH and 24 cc water.
After stirring to insure a homogeneous blend, the sample was placed in a jar in an oven at 75C. After 2 hrs. the sample was suspended in 95-100~ ethanol and filtered. The resulting filter cake was resuspended in a 1:1 (by volume) ethanol-water mixture, pH was adjusted to 7.5, and the sample was filtered and washed repeatedly with the 1:1 ethanol-water. Final nitrogen on the purified product was 0.48~J and therefore an acetal nitrogen of 0.22~ was obtained by the "dry" reaction.
Example II
This example describes the preparation of novel starch acetals using reagents other than the acetamide reagents of the previous example.
Acetal Reagent Preparation Reagent D - N-~2,2-Dimethoxyethyl)-N-methyl-3-chloropropionamide, which 0 ~ OCH3 has the formula Cl-cH2-cH2-c-7-cH2 CH , was prepared according . CH3 ~OCH3 to the procedure used to make Reagent A except the chloropropionyl ~;~37~

chloride (32.7 g.) was substituted for chloroacetyl chloride. The product was isolated as a pale yellow 1iquid.
N-(2,2 Dimethoxyethyl)-N-methyl acrylamide, which has the o OCH3 formula CH2=CH C-N-CH2-C ~ , was prepared according to the proce-CH3 \ OCH3 dure used to make Reagent A except that acryloyl chloride (23.3 9.) was used instead of chloroacetyl chloride and 4-t-butylcatechol (0.1 g.) was added to the organic phase before removal of the solvent. The final product was isolated as a clear liquid by distillation (65-66C
0.2-0.3 mm Hg.).
Reagent F - 1,2-Epoxy-3,3-dimethoxypropane, which has the formula ~ 0 ~.OC2H5 CH2 - CH-CH , was prepared from acrolein as descr1bed D. T.

Weisblat et al. See J. Am. Chem. Soc., Vol. 75, p. 5~93 (1953).
Reagent G - N-(2,2-Dimethoxyethyl)-N,N-dimethyl-N-(2,3-epoxypropyl) ammonium chloride, which has the formula / O \ CH3 / OCH3 CH2 - CH-CH2-N+-CU2-CH Cl~, was prepared by adjusting the CH3 \ OCH3 pH of a 40~ solution of dimethylaminoacetaldehyde diethyl acetal (30.01 9.) to pH 7.5 with concentrated HCl and then dropping epichlorohydrin (22.8 9.) into the solution. The reaction mixture was held for 2 hrs.
while maintaining the pH between 7.5-8.5 by the addition of concentrat-ed HCl or 50~ NaOH. The temperature was maintained at 30-35C. Impuri-ties and excess reagent were removed from the reaction mixture by extrac-tion with ethyl acetate (4 times with 65 ml. each time). The product was ~237~Z~L

isolated as an aqueous solution which ~as pH adjusted to 7Ø
Rea~ent H - 1,2-Epoxy-3,3-dimethyoxypropane, which has the formula / O\ /OCH3 CH2 - CH-CH , was prepared using the procedure of D. T. Weisblat ~ CH3 except that trimethyl orthoformate was used in place of triethyl ortho-formate.
Reagent I - 1,2-Epoxyethyl-1,3-dioxalane, which has the farmula CH2 - CH-C ~ ¦ , can be prepared by a modification of the procedure \Q--CH2 of D.T. Weisblat et al. The ethylene acetal of acrolein is used instead of the diethyl acetal.
Reagent J - 3-(Chloromethyl)-N-(2,2-dimethoxyethyl)-N-methyl benzamide, which has the formula ~ I - N - CH2 - CH , was prepared according to the Cl ~2 lH3 \ OCH3 procedure used to make Reagent A except that 3-(chloromethyl) benzoyl chloride (48.6 g.) was used instead of chloroacetyl chloride. The product was isolated as a pale yellow oil after removal of the solvent.
It contained 4.8~ N (theoretical 5.15~.
Starch Reactions The starch reactions with Reagents D to G and J were carried out as in Example I, Part A, No. 1 using 30 9. Na2S04 in the slurry of starch (100 9.) and a solution of 3.4 9. NaOH and S 9. Na2S04 in 70 9. water to adjust the pH. The reagent amounts, starch base, and nitrogen content are shown below.

~L%3~ 4 ~ Cationic N ~ Acetal N
Starch Basein B _ e Acetal Rea~t in Cationic Acetal Waxy corn 0.270 15X n 0.240 Waxy corn 0.270 lZ~ E 0.360 Waxy corn 0.270 12~ F None*
Corn None 15~ G 0.380 Corn None 10~ J 0.279 *No nitrogen in acetal reagent ~
This example describes the preparation of acetal starch derivatives other than cationic derivatives.
A. Potato, waxy maize, and tapioca starch were reacted with Reagent A of Example I using the following procedure: 100 9. of starch were slurried in 150 ml. water containing 30 g Na2S04. A solution of 3.4 9. NaOH, 5 9. Na2S04 and 70 9. water was added slowly to the slurry, followed by 12 9. of Reagent A. The samples were reacted 45C, 16 hrs. and worked up using the method in example 1. Acetal nitrogen was 0.40~, 0.46X and 0.41~, respectively.
B. High amylose corn starch (70~ amylose) was reacted with 20~ of Reagent A using a procedure similar to that described in Examp1e 1 -Par~ C except that the starch was not treated with DEC after reaction with the acetal reagent. The product contained 0.99~ acetal nitrogen.
C. A waxy maize 85 fluidity starch was reacted wi~h 15% of Reagent A (see Example 1) using the procedure of Part B above. The product contained 0.75~ acetal nitrogen.
D. A waxy maize starch cross-linked with phosphorus oxychloride and containing hydroxypropyl groups via reaction with propylene oxide was reacted with Reagent A using the procedure described above in A.

~37: LZ9~

EXAMPLE IV
This example describes the preparation of guar gum acetals and a gum arabic acetal.
Part A
A cationic guar gum was prepared by slurrying 60 parts of yuar gum in 360 parts of 50~ aqueous isopropanol, heating the slurry to 40C, and bubbling nitrogen gas into the slurry for 1 hr. A total of 7.2 parts of 50~ aqueous sodium hydroxide was added, the slurry was stirred for about 10 min.J and 4.8 parts of 50~ aqueous DEC were added. The slurry was stirred for 4 hr. at 40C. The pH was lowered to 8.2 with dilute acetic acid, and the derivative was recovered by filtration, washed with aqueous isopropanol followed by 100~ isopropanol, and air-dried. It contained 0.93~ N.
The resulting derivative may then be reslurried as above in aqueous isopropanol and further treated with 3 parts potassium iodide, 2.4 parts sodium hydroxide, and 1.2 parts of Reagent A of Example I. The reaction should be carried out for about 16 hr. at 45C. The derivative may be recovered and purified as above and should be useful in imparting wet and dry strength to paper.
Part B
A total of 100 9. of guar gum was slurried in 600 ml. of a mixture of 1:1 water and isopropanol. The mixture was heated to 45C, and 12.5 9. of 40~ sodium hydroxide were added. The mixture reacted for about 16 hours (overnight) with stirring. It was neutralized with acetic acid to p~ 8.5, filtered, and washed with 1500 ml. of the isopropanol-water mixture. The initial nitrogen on the guar was 0.677~; after the above alkali-solvent treatment it was reduced to 0.25~.
The treated guar ~30 9.) was slurried in 100 ml. of the isopro-~237~2~

panol-water mixture followed by 24.7 9. of 20~ sodium hydroxide. The temperature WdS raised to 45C and 51 9. of Reagent A (see Example I) were added. The reaction was allowed to run 4 hours, followed by neutralization with acetic acid to pH 8.5, filtration, and washing with 1500 ml. of the isopropanol-water mixture. The g N on the final gum acetal was 0.54~.
Part C
Gum arabic (25 9.) was added to 50 ml. of water which contained 0.62 9. of sodium hydroxide (pH 11.3). Then 2.5 9. of Reagent A of Example I was added (10~ based on the wt. of the gum). The slurry was reacted for 6 hours at 45C, the pH was adjusted to 7.5 with 10~
hydrochloric acid, and the soluble gum arabic derivative was recovered - by alcohol (i.e., ethanol) precipitation. The N content was 0.535%
compared with 0.344~ for the underivatized base.
EXAMPLE V
This example describes the preparation of cellulose acetals. They were prepared using the general procedure of U.S. Pat. No. 4,129,722 (cited previously).
A total of 20 9. SPAN-80 (a surfactant available from Hercules) was dissolved in 200 9. Isopar E (petroleum solvent composed mostly of ~8 isoparafins, b. p. of 116-142C) in a 500 ml. flask equipped with a thermometer, mechanical agitator, condenser and suitable size dropping funnels. Cationic hydroxyethylcellulose (50 9.) grafted with dimethyl-diallylammonium chloride (DMDAAC) was added to the solvent-surfactant blend. Then 15 9~ of Reagent A of Example I was dissolved in 10 ml.
water and added to the reaction mixture over a 30 min. period. This was followed by addition of 8 ml. of 10 N NaOH. The temperature was * Trade Mark ', ~:3~ 2~
- 2, -raised to 50C and held 3 hrs., followed by cooling to room temperature and neutralization to pH 8.0 with HCl. The cellulose derivative was filtered, washed with Isopar E and dried. Cationic N was 0.81~. Total N after dialysis was 1.43%. Acetal N was therefore 0.62b.
Using an identical procedure methyl cellulose (Methocel from Dow *

Chemical Co.) and cellulose (C-8002 alpha-cellulose from Sigma Co.) were reacted with 30~ and 40~, respectively, of Reagent A. Acetal N on the methyl cellulose was 0.54~ before and after dialysis. Acetal N on the alpha-cellulose was 0.3~ after exhaustive washing with water.
Example VI
The following chart (A) shows a list of reactants which, when O / OA
reacted, will give acetamide reagents of the type X-CH2-C-N-R2-CH
\ OA' that can be reacted with polysaccharides such as starch, gum, and cellulose using the procedures of Examples I, IY or V. The indicated polysaccharide acetals should result from the reaction.
Example VII
The following chart (B) shows a list of reactants which, when reacted and then convent;onally oxid;~ed, w;ll give an epoxide reagent of the type / O / OA
HC - C CH

¦ l4 ~ OA~
R R
that can be reacted with polysaccharides such as starch, gum, or cellu'lose using the procedure for Reagent F o~ Example II, when starch is the base or a modification of that procedure when gum or cellulose are the bases~

* Trade ~lark ~37~Z~
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~ ~ (_) ~_) ~C I
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EXAMPLE VIII
This example describes the preparation of the aldehydes.
The starch acetals were converted to the corresponding aldehydes by slurrying the acetal in water (e.g., 100 parts of water/1 part of starch~ and adjusting the pH to 2.5-3.0 with a dilute solution of hydrochloric acid. The starch ace~als were cooked in a boiling water bath, prior to, after, or during the acidification to gelatinize the starch. The total cooking time was about 20 mins. The slurry was stirred during the acid addition and/or initial cooking. The cook was cooled rapidly.
The cellulose acetals ~ere converted to the corresponding aldehydes as above but it was not necessary to cook the cellulose derivatives.
The gum acetals can be conYerted to the corresponding aldehydes in a like manner.
Example IX
This example describes the use of the cationic starch aldehydes and cationic cellulose aldehyde as paper strength additives. The aldehydes were added to the indicated paper furnish and handsheets were prepared at pH 6.0, dried at 121C (250F.), cooled, cut into 1 in. strips, and cured at 105C (221F.) for 5 min. The wet and dry tensile strengths are reported as breaking length (B.L.). The addition level was 20 lb./ton.
The derivatives and paper test results are given in Table I. All but No. 21 imparted initial wet strength and dry strength and were superior to the prior art cationic dialdehyde starch in initial wet strength. The cationic cellulose aldehyde provided the highest wet and dry strength.

~;~3~24 Example X
This example shows the ef~ect of pH on the aldehyde generation.
It also as illustrates the preparation of starch acetals containing mixed acetal substituent groups.
Part A - Preparation of The Mixed Acetal Reagents Reagents K, L, and M were prepared by stirring 25 9. portions of Reagent A of Example I with ~00 ml. of isopropanol (Reagent K), n-but-anol (Reagent L), and tert-butanol (Reagent M) with 5 drops of concen-trated hydrochloric acid for about 18 hours at room temperature. The reaction mixtures were filtered and s~ripped on a rotary evaporator at 40-50C, ~ollowed by vacuum pumping at 0.5 mm. Hg for 2 hours at room temperature. NMR analysis showed that about 10-20~ of the dimeth-oxy groups (i.e., -CH(OCH3)z) had been exchanged with the respective solvents thus introducing isopropoxy groups (i.e.,-CH(OCH(CH3)2)2.
n-butoxy groups (i.e., -CH(OCH2CH2CH2CH3)2), (and tert-butoxy groups -CH(OC(CH3)3)2)-Part B - Preparation of The Starch D~rivatives Cationic waxy maize acetal starch derivatives were prepared using the above reagents and the procedure of Example I, Part A (3).
ZO Nitrogen analysis showed the following:
Starch Reagent ~ Cationic N ~ Acetal N
-21 J 0.28 0.37 22 K 0. 28 0 . 33 23 L 0.28 0.34 2~ Control - 0.28 Part C - Evaluation of Wet Strength after Conversion To Aldehyde at Various pH Values One gram samples of the above starch acetals were slurried in s E ~ 7~;Z9~
>I , Cl~ > O ~ 1 o o ~ o V~ ~
-a~ .
3 = E
~ c ~ ~~ n ~ ~ c~l ~ c~ ~ O o u7 oo C~
., ~ .
~ V~ ~
_ _ Z ~>
o ~ ~ ~c> ~ ~ o o 1~ ~ ~ oo ~ r~ . ~ o d alo 1~ o ~ ~ 1~~ O O~ OC~ ~ ~ C~ ~ D ~ 00 ~ c~ zo o o o o o o o o o o o o o o o o z o ~ c t o Q. C~ Q_ ~ n. Q. ~ ~ ~ ~ ~ ~ Q. ~ ~ ~ ~ ~ ~_ ~ C
O ~ ~ ~ - - -rd ~- ~ o O ~ 2 0 0 0 N ~D O O O O O O O ~ ) N C~ l S

. x O ~ ~ ~ ~ 0 ~ O r~ I~ O r~ oo o o . o o o ~_ O OOOOOOOOOOOO O O OOOO
z '~ a~ x O ~ IIJ

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o ,a o ~ o o ~ o o o o ~ (a-_ ~ a ~ ~ o ._ ~n Z ~ 3 ~ ~ 3 ~ ~ 3 3 T ~ 3 3 3 3 ~ ~ 2 0 O V ~ ~ ~ I
o I o ~ ~ O ~ l ~ d ~ U7 ~ 00 0`1 0 z m ~ 2 D ~ 37~ 4 L ~1 .r_ ~ V o C ':t aJ
Cl _ _~ L C ~1 ~ O I_ -_ ~ ~D ~ r') ~
V~ L~_ Z '' ~; - ~ C ;r~

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~ V I aU C ~D ~ ~ ~ ~ O
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~L~3~

water to a total weight of 100 9. and the pH was adjusted to pH 2.5 or 5Ø The starches were cooked and evaluated in paper handsheets as in Example YIII, Part A. The results are shown in Table II.
Table II

Cationic Initial Starch Derivative No.Cook pH (lb./ton) Wet Strength 21 2.5 10 279 21 2.5 20 409 21 5.0 10 82 21 5.0 20 287 22 2.5 10 231 22 2.5 20 370 22 5.0 10 91 22 5.0 20 279 23 2.5 10 251 23 2.5 20 413 23 5.0 10 97 23 5.0 20 29 Control 5.0 20 89 (Cationic Starch Base) The results show that the wet strength was much higher for starch acetal derivatives cooked at pH 2.5 ra~her than pH 5Ø At the higher addition level the wet strength increased even for the derivatives cooked at the higher pH. This shows aldehydes were generated at the higher pH.
Example XI
This example describes the temporary wet strength provided by the cationic aldehydes. The aldehydes were eYaluated for both tissue/
toweling applications ~Part A) and board and bag applications (Part B).
P rt A
The deriYatives evaluated were the aldehydes prepared from a cationic waxy corn starch acetal similar to the derivative of Example ~L~23~Z~

I - Part A-1 and the cationic cellulose acetal Example V, One starch aldehyde was cooked as in Example VIII, but at a pH of 7, to provide a liquid starch acetal. The acetal was then hydrolyzed to the aldehyde by adausting the pH to 2.5 and then heating at 90-100C for 10-15 min.
It was then added to the paper furnish. The other starch aldehyde was prepared by cooking the acetal at pH 2.5.
One cationic cellulose acetal was cooked as above at pH 7 to provide a liquid cellulose acetal. It was then hydrolyzed to the aldehyde by adjusting the pH to 2.5 and cooked as above. The other cellulose acetal was cooked at pH 2.5. For comparison, the cationic starch base, as well as cationic starch acetal which had been cooked at a pH of 7 but not hydrolyzed, were evaluated (see Table II).
The addition 1evel was 20 lb./ton. The furnish was a 50:50 bleached sulfite:bleached Kraft. The paper sheets were prepared on the Noble and Wood Sheet Mold. The paper weight was about 5 lb./1000 sq.
ft. The wet and dry strength results are shown in Table III.
The results show that all the cationic derivatives improved the dr strength with the cationic starch aldehyde providing the most improve-ment. Only the cationic aldehydes improved the wet strength. The starch aldehyde prepared by simultaneously cooking and hydrolzing the acetal was better than the precooked and subsequently hydrolyzed acetal in dry strength, initial wet strength, and temporary wet strength.
TABLE III

Wet Strength ~ Relative Dry (B.L. in m.) _ Wet Strength*
Strenqth 30 16 30 1~
Sample(B.L. in m.) Initial Min. Hr.Initial Min. Hr.
Blank1210 49 20 33 4.1 1.7 2.7 Cationic1640 83 43 N.D. S.1 2.6 2.1 Starch Base ~;~3~

TABLE III (cont'd) Wet Strength % Relative Dry (B.L. in m.) Wet Strength*
Stren~th 30 16 30 16 5 Sample (B.L. in m.) Initial Min. Hr. Initial Min. Hr Cationic 1530 71 51 32 4.7 3.3 2.1 Starch Acetal (comparative) Cationic Starch 2140 382 26~ 122 17.9 12.1 5.7 Starch Aldehyde (cooked at pH 2.5) Cationic 1830 296 217 N.D. 16.2 11.9 N.D
Starch Aldehyde (precooked acetal) Cationic 1550 335 25B N.D. 21.6 16.6 N.D
Cellulose Aldehyde Cationic -1610 350 277 N.D. 21.7 17.2 N.D.
Cellulose Aldehyde (precooked acetal) *Wet Strength/Dry Strength x 100.
N.D. - Not determined.
Part B
Some of the derivatiYes were also evaluated at 20 lb./ton in a furnish of 100~ unbleached Kraft containing 3~ alum (i.e., aluminum sulfate). The paper weight was about 42 lb./1000 sq. ft. The results are shown in Table IV.
The results again show that all the cationic derivatives improved the dry strength with the cellulose aldehydes being the best. Only the aldehydes provided wet strength.
TABLE IV
Wet Strength ~ Relative Dry(B.L. in m.r Wet Strength _ Strenath 30 16 ~ 30 16 Sample (B.L. in m.) Initial Min. Hr. Initial ~in. Hr.
Blank 5330 516 455 360 9.7 8.5 6.8 ~;~3~

TABLE IV (cont'd) Wet Stren~th g Relative Dry (B.L. in m.) Wet Strength Strenqth 30 16 30 16 5 Sample (B.L. in m.T Initial Min. Hr. Initial Min. Hr.
Cationic Starch 6050 533 471 N.D.8.8 7.8 N.D.
Starch Base Cationic 5720 507 404 N.D.8.9 7.1 N.D.
10 Starch Acetal Cationic 5711 1100 746 63719.3 13.1 11.2 Starch Aldehyde (cooked at pH 2.5) Cationic 6710 1660 1400 116024.7 20.9 17.3 15 Cellulose Aldehyde Cationic 6160 1640 1420 N.D.26.6 23.1 N.D.
Cellulose Aldehyde (precooked acetal) In summary, the present invention is seen to provide polysaccharide aldehydes, which are generally useful for imparting strength to paper, as well as the corresponding acetals us~ed in the preparation of the aldehydes. It further provides a non-oxidative method for introducing aldehyde groups into polysaccharides.

Claims (21)

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:

1. An aldehyde-containing polysaccharide derivative having the general structure , wherein Sacch-0 represents a polysaccharide molecule; R is (CH2)n or a divalent aromatic group, with n being 0 or greater; R1, R6, and R7 are independently hydrogen or an alkyl, aryl, aralkyl, or alkaryl group; R2, R5 and R8 are independently (CH2)m with m being 1-6;
R3 is hydrogen or a lower alkyl group; R4 is hydrogen or an alkyl, aryl, aralkyl, or alkaryl group; and Y is an anion.

2. A acetal-containing polysaccharide derivative having the general structure wherein Sacch-0 represents a polysaccharide molecule; R9 is (CH2)n or an aromatic group, with n being 0 or greater, with the proviso that n is at least 1 when the polysaccharide molecule is a starch molecule; R1, R6, and R7 are independently hydrogen or an alkyl, aryl, aralkyl, or alkaryl group; R2, R5, and R8 are independently (CH2)m with m being 1-6; R3 is hydrogen or a lower alkyl; and R4 is hydrogen or an alkyl, aryl, aralkyl, or alkaryl group; A and A' are independently a lower alkyl or A and A' together form at least a 5-membered cyclic acetal; and Y is an anion.

3. The derivative of Claim 1, wherein the polysaccharide is a starch, cellulose, or gum.

4. The derivative of Claim 2, wherein the polysaccharide is a starch, cellulose, or gum.

5. The derivative of Claim 3 or 4, wherein the starch is a waxy maize, corn, high amylose corn, potato, rice, sweet potato, or tapioca starch; R1, R6, and R7 are independently hydrogen or a methyl group; m is 1; R3 and R4 are hydrogen; and Y is a chloride, sulfate, or nitrate anion.

6. The derivative of Claim 3 or 4, wherein the starch is a waxy maize, corn, high amylose corn, potato, rice, sweet potato, or tapioca starch; R1, R6, and R7 are independently hydrogen or a methyl group; m is 1; R3 and R4 are hydrogen; and Y is a chloride, sulfate, or nitrate anion and contains one or more cationic, anionic, nonionic or zwitterionic group.

7. The derivative of Claim 3 or 4, wherein the starch contains one or more cationic, anionic, nonionic or zwitterionic group and n is 1; m is 1; R1 is hydrogen or methyl; R3 and R4 are hydrogen; and R6 and R7 are methyl.

8. The derivative of Claim 1, wherein the polysaccharide is a starch and n is 0 or 1.

9. The derivative of Claim 1, wherein the polysaccharide is a gum and n is 0 or 1.

10. The derivative of Claim 1, wherein the polysaccharide is a cellulose and n is 0 or 1.

11. A method for preparing the derivative of Claim 1, which comprises the steps of:
(a) reacting a polysaccharide molecule, in the presence of an alkali, with an acetal-containing derivatizing reagent having the general structure where Z is a terminal organic group capable of reacting with the polysaccharide molecule to form an ether derivative and is selected from the group consisting of an epoxide, an ethylenically unsaturated group, a halohydrin, and a halogen; R11 , is a divalent organic group containing no polysaccharide-reactive substituents; and A and A' are independently a lower alkyl or A and A' together form at least a 5-membered cyclic acetal;

(b) hydrolyzing the resulting acetal-containing polysaccharide derivative by adjusting the pH to less than 7; and (c) isolating the resulting aldehyde-containing polysaccharide derivative.

12. The method of Claim 11, wherein the reagent is used in an amount of about 0.5 to 100% by weight, based on dry polysaccharide, and wherein the pH in step (b) is adjusted to about 2-4.

13. The method of Claim 11, wherein the polysaccharide is starch and the reaction of step (a) is carried out in the presence of a catalyst selected from the group consisting of an alkali metal iodide, a quarternary ammonium iodide, and an amine iodide.

14. The method of Claim 13, wherein the acetal-containing derivatizing reagent Z- R? is R9 is (CH2)n, with n being 0 or 1; R1, R6, and R7 are hydrogen or methyl; R2, R5, and R8 are independently (CH2)m, with m being 1 or 2; R3 and R4 are hydrogen; X is chlorine, bromine, or iodine; and Y is an anion.

15. The method of Claim 14, wherein n is 1; m is 1; R1 is hydrogen or methyl; R3 and R4 are hydrogen; and R6 and R7 are methyl.

16. The method of Claim 15, wherein the polysaccharide is a gum.

17. The method of Claim 15, wherein the polysaccharide is a cellulose.

18. The method of claim 14, wherein the starch is a waxy maize, corn, high amylose corn, potato, rice, sweet potato, or tapioca starch, and R1, R6, and R7 are independently hydrogen or a methyl group; m is 1; R3 and R4 are hydrogen; and Y is a chloride, sulfate, or nitrate anion.

19. The method of Claim 18, wherein the starch contains one or more cationic, anionic, nonionic or zwitterionic group.

20. In a method for making paper having dry strength, wet strength, temporary wet strength, or combinations thereof, the step which comprises adding, as a strength aid, to the stock at any stage prior to forming a web, an effective amount of the derivative of Claim 1.

21. The paper containing the strength aid of Claim 20.