CA1191791A - Dentifrice containing a siliceous polishing material and resinous poly(ethylene oxide) - Google Patents

Abstract

ABSTRACT OF THE DISCLOSURE
A dentifrice containing a siliceous polishing material and binding or gelling agent including resinous poly(ethylene oxide). The polishing agent flocculates in the presence of the resinous poly(ethylene oxide) and provides the dentifrice with desirable stain removal effective-ness without unduly raising dentin abrasion. Foaming character is also achieved when a polyoxyethylenepolyoxypropylene block copolymer and xanthan are present,

Description

g~91' This invention relates to a dentifrice which provides effective stain removal.
; Some dentifrices are known which provide excellent foaming with the use of the nonionic surface active agent block copolymer of polyoxyethylene-polyoxypropylene with xanthan as gelling or binding agent in which resinous poly~ethylene oxide) may also be present. The dentifrice thereof typically contains a dentally acceptable polishing agent such as a siliceous material; for instance, colloidal silica or synthetic alkali metal aluminosilicate complex, that is, material in which silica contains combined alumina.
Based upon prior art considerations, as disclosed in United States Patent 3,020,230 to Smith, wherein silica material is stated to coagulate or flocculate in the presence of resinous poly-~ethylene oxide) in order to precipitate it from a liquid sus-pension, one skilled in the dentifrice art would not have been ~ led to use silica materials in a dentifrice containing resinous `~ - 1-~ L7~'31 po~y(ethylene oxide). Indeed, in U. S. Patent 2,991,229 to Ivlson, polishing a~entc or abrasivcs d1BC1OSed ln ~ tootll~astc containing poly(ethylene oxlde) were "tricalcium phosphate, di-cslcium phosphate and c~lclum carbonate and the llke"; but not`
sillca materialS-It is an advantage of the present lnvention that a denti-frice ls provided with lmproved stain removal which has'accept-able cosmetic rheology and dentln abrasion characteristics.
It i5 a further advantage that deslrable foaming is achieved with inclusion of polyoxyethylene-poly oxypropylene block copoly-mer and xanthan in the dentifrice.
Further advaneages will be apparent from consideration of the following dlsclosure.
In accordance with certain of lts aspects, this invention relates to a dentifrice comprising about 20-80% by weight of a liquid humectant vehicle, about 5-50% by welght of a siliceous polishing material and about 0'.05-5X-by weight of a reslnous poly(ethylene oxide), ~aid dentifrice containing florculated partlcles of said ~iliceous polishing agent in the presence of said poly(ethylene oxlde).
The proportion of the siliceous poli6hing agent content is in the range rom 5% to 50% by weight of the dentifrice, prefera bly f:rom 10% to'30% such a~ from 10% ~o 25X. One such polishing sgent ls a complex alkali metal aluminosilicate having a re-fractive lndex of from 1,44 to 1.47 and contalning at~least 70%
sllica, up to 10% alumina, such as about 0.1-10% e.g. about 0.1-3%, preferably up to about 20% of moisture, ~uch as about 0.5-10%; and up to Abo~t 107, of alkali metal ox-ide.- Typically, this ~aterial has a particle size in the range fram 1 to 35 mlcrons, peferably from 2 to 20 mlcrons, e.g. 2 to 4 microns. The pre-ferred moisturc content is from 10% to 20% measured by i~nition at 1000C and the typlcal content of alkall metal oxide i8 from 5% to 10% ~!1 ' I :L1S~1791 Generally, the polishing agent has a loose bulk density of up to 0.2g/cc, such as from 0.07 to 0.12g/cc. ~nothcr suitablc typc of pollshing a8ent i3 porous amorphotls silicic anhydridc llnvlng an average particle si~e preferably below 20 microns and above l micron, a surface area of at least 200.m2/g, preferably at least 300 m2/g, and a bulk density of at least 0.15 g/cm3, preferably at least 0.30 g/cm3, such as a dehydrated sllica hydrogel (i.e. a xerogel), preferably of ~he well known regular density or lntermedlate density type. Examples af such amorphous sillclc ~nhydrlde pollshing agents are "Syloid 63", "SyloId 72", and "Syloid 74" ~SYLOID is a trade mark) which are described in "The Davlson Family of Syloid Silicas" published by their.manu-facturer, Grace9 Davison Chemical Company. "Santocel lOO" of Monsanto (SANTOCEL ls a trade mark), is also a sultable dental abrasive. "Syloid 77" has ~average particle size of about ~
microns, a surface area of about 340 m2/g bulk density of about 1.77 g/cm3. For "Syloid 63" the corresponding fi~ures are about 9 microns, about 675 m2/g and about 0.4 g/ ~3. A grade of "Santocel lOO" has a surface area of about 239 m2/g and a bulk density of about 0.24 g/cm3. These amorphous silicic anhydrides may be used singly or in mixtures.
Resinous poly(ethylene oxide) has been disclosed as a denti-frice gelling or b~nding agent in U. S. Patent 2,991,229 to Ivison. Its prasence smoothed the texture of the dentifrice; -indeed, the dentifrice of the present lnvention has a smooth texture even thougn flocculated partlcles from the siliceous polislling mncerlnl are prcsent.
The poly(ethylene oxides) employcd in thls invention are ~olid, colorlcss, wnter-~cluble reslns. Thcy nppear to form homogeneous systems in water ln all proportions, although the 1~9~

relatively higher molecular weight ethylene oxide polymers merely swell on the addition of small amounts of water. On the addition of greater amounts of water, the polymers pass into solution. The water solutions are viscous, the viscosity increasing both with the concentration of the polymer in the solution and the reduced viscosity of the polymer.
The ethylene oxide polymers employed in this invention show little change in melting point with reduced viscosity (an indication of increased molecular weight) and the melting point, as measured by change in stiffness with temperature, was found to be about 65 + 2C
throughout the range of reduced viscosities of from about 1.0 to about 10, and greater. These polymers, upon X-ray examination, disclose a crystalline structure similar to that exhibited by polyethylene. The crystallization temperature, as determined from measuring the break in the cooling curve, is about 55C. To facilitate the understanding of the instant invention, various terms will be defined. At the out-set it should be noted that the word "poly~ethylene oxide)" as used throughout the specification and claims refers to ethylene oxide poly-mers which have a reduced viscosity in acetonitrile of at least 0.5 and upwards to 75, and higher.
Unless otherwise stated, by the term "reduced viscosity", as used herein, is meant a value obtained by dividing the specific viscosity by the concentration of the ethylene oxide polymer in the solution, the concentration being measured in grams of polymer per 100 milliliters of solvent at a given temperature, and is regarded as a mea-sure of molecular weight. The specific viscosity is obtained by divid-ing the difference between the viscosity of the solution and the viscosity of the solvent by the viscosity of the solvent. The reduced viscosities herein referred to are measured at a concentration of 0.2 grams of poly (ethylene oxide) in 100 milliliters of acetonitrile at 30C (unless stated otherwise).
Granular poly(etllylene oxi~c) rcsults from the suspcn~ion polymerization of an agltated reactlon mixture comprising ethylene oxide in contsct with a polymerizatlon catalyst therefor and in the presence of an inert organic diluen~, e.g., heptane, in which ethylene oxide is soluble and the resulting poly(ethy-lene oxide) is insoluble. Granular poly(ethylene oxide) thus produced is obtained i~ a finely-divided solld particle state and resembles finely-divlded san~ ln particle size. Unlike the granular poly(ethylene oxide) resul~ing from the suspension poly-merization process, the bulk and solutlon polymerizatlon processes yield a polymer whichis.asubst2ntially homogeneous mass either conforming to the shape of the reaction vessel or, after drlv~ng ofEthe org~nic medium, for example, by mechanical extrusion, e.g.
Marshall ~Sill (undar vaccum and at sl.ightly elevated temperatures) .
resembles l~yers or sheets. This polymer subsequently can be reduced in particle size, for example, by dicing or the like.
The term "granular" rPfers to the particle size of the ethylene oxide polymers prepared by suspension polymeri~ation.
A granular product is one whlch is ln a free-flowing statP and comprlses partlcles averaglng les~ than 5 mesh in size (U. S.
St~ndard Sl~e Sieve).
The poly(ethylene oxide) comprises ahout 0.05-5% by weight of the dentifrlce, prefersbly 8bout 0.1 - 1.5X.
In the dentlfrice, the ~iliceou8 polishlng agent flocculntcs in itu in the presence of the poly(ethylene oxi~e). Thc ~loccula~e~ particles typical.l~y may agglomcrate with each othcr have apparent pnrtlcle slzcs Up to about 250 micron~ or morc, typlcally nhollt 44 to ~77 n-icron~; ln o~her words, ~he flocculnte(l particles typically pass through a screen of U' S. Sleve No. 80 and nre retained on a screen of U. S. Sleve No. 325.

In spite of the presence of the flocculated particles the dentifrice is readily formulated to have a desirable appearance ¦and a rheological texture without an undue "lumpy" appearance or "gritty" feel.
The liquid vehicle of the dentifrice comprises water, humectant or mixtures thereof in amount of about 20-80%, prefera-bly about 30-60%. When a substantially visually clear gel ls desired, water is generally not present in amount abo~e about 10% typically about 2-5%. When the dentifrice is opacified, greater amounts of water may be present. Typical humec~ants include sorbitol (as 70% aqueous solution), glycerine, maltitol, xylitol, polyethylene glycol ~00 and polyethylene glycol 600.
Most preferably the dentifrice contains about 25-50% maltitol.
Maltitol may assist ln improving stain removal when present in th dentifrice of the invention. It is noted that maltitol is disclo sed as a dentifrlce ingredient in Japanese Patent Publications 73110241 and 65/15120.
The liquid ~ehicle and gelling agent including resinous poly(ethylene oxide) and other components of the dentifrice are proportioned to form a cream or gel mass of desired consistency which is extrudible from an aerosol or pump container or a col-lapsible tube (for example aluminum, lead or plastic~.
In addition to the resinous poly(ethylene oxide), further gelling or binding agent such as sodium carboxymethyl cellulose, Irish moss, xanthan and the like may be present in amount of about 0.5-7%. Xanthan is preferred. The total amount of gelling or binding agent in the dentlfrice can be about 0.1-12~ by weight ~ nthan gum i8 a fermentation product prepared by action of the bacteria of the genus Xanthomonas upon carbohydrates. Four epecle6 of Xa l monos, viz. X. cam~etrl:. X. ~ li, X.

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malvocenrum, ancl . carotne are rcportccl in thc literaturc to be the most eEficicnt gum producers. ~lthou&ll the exnct chem~cul ~tructure is not determined, it is generally accepted to be a heteropolysaccharide with a molecular weight of several million.
It contains D-glucose, D-mannose and D-glucoronic acid in molar ratlo of 2.8:3:2Ø The molecule contalns 4.7% acetyl and about 3% pyruvate. The proposed chemical structure configuatlon can be found in McNe21y and Kang, Industrial Gums, ~d, R. L. Whistler Ch XXI, 2nd Edition, New York, 1973. The procedure for growin~, isolating and purifylng the xanthan gum is found in ~anufacturing Chemist, May 1960, pages 206-208 (inculding mention at page 20~
of potential use o gums therein described ~or formulating toor.h-pastes).
Use of special grades of xanthan gum, such as describPd in U. S. Patent No. 4,263,399 are withi~ the scope of this lnvention A grade described in U. S. Patent 4,263,399 i5 A xanthan gum in which up to about 1,6% of the carbo~yl groups are bound to cal-cium and tlle remaining carbo~yl groups are bound to sodium, potassium, a mixture of sodium and potassium or other non-calcium catlons.
The dentlfrice may contain an anionic, nonionic> cationic or amphoterlc surface active agent to achleve incrcased prophy-lactic DCtiOn, assist in acllievin~ thorough an~ complete dis-persion o~ the instant compositions in the oral cavlty and ren~er tl~o ;nstant compositions more cosmctlc;llly ucceptal-le.
A pre~erred sur~nce actlve ngellt i~ u nolllolllc block cvpo~y-mer containing po1.yoxyethylene anll polyoxypropylelle. Such block co~olymerR nre nvni]nble from Wyan(lotte ~:hclllicAls Corp. under the trade mark "P]uronic". They mny be iqui-l, paste, or solid and are g~nerally chemically defined in terms of the molecular weight of the polyoxypropylene hydrophob~c moiety and the percen by welght of the polyoxyethylene hydrophilic moiety.
_~_ The following block copolymers are available from Wyandotte:

PLURONIC Pl~YSICAl. MOl.. Wl`.
NUMBER CHARACTER HYDROPHIL HYDROPHOBE .

L 81 LIQ~ID 10 2250 L 31 ~I~UID 10 950 L 72 LIQUID 20 2~5~

L 42 LIQUI~ 20 1200 P 104 PAST~ 40 3250 P 65 PASTE 50 175n . .
The preferred ncnionic block copolymers are solid (or flake) materials and the mo~t preferrdd are Pluronic 108 (80YD polyoxy- ` .
ethylene: 3250 molecular weight polyoxypropylene~ and F 87 (70%

polyoxyethylene: 2250 molecular weight polyoxypropylene).
Othor noniolllc ~nrfnee actlvc tl~ l`ll~S Whl.('ll IlI;ly ~ OyCd include condensates of sorbitan monofiterate w~th flpproximately 20 ~olés of ethylene-oxide. Amphoteric agents include qu~terni~ed imidazole derivatives which are available under the trademark "Miranol" such as Mira'nol C2M.
::' . -8-19~L7'11 Suitable types vf anionlc detergents are water-soluble salts of higher fatty acid monoglyceride monosulphates, 9~1Ch as the sodium salt of the monosulphated monoglyceride of hydrogenated coconut oil fatty acids, higher alkyl sulphates, such as sodium lauryl sulphate, alkyl aryl sulphonates, such as sodium dodecyl benzene sulphonate, olefin sulphonates, such as sodium olefin sulphonate in which the olefin group contains 12-~1 carbon atoms, higher alkyl sulphoacetates, higher fatty acid ester of 1,2-dihydroxy propane sulphonates, and the substantially saturated higher aliphatic acyl amides of lower aliphatic amino carboxylic acid compounds, such as those having 12 _16 carbons in the fa~ty acid, alkyl or acyl radicals, and the like~ Examples of the last men-tioned amides are N-lauroyl sarcosine and the sodium, potassium, and ethanolamine salts of N-lauroyl, N-myristoyl or N-palmitoyl sarcosine, which could be substantially free from soap or similar higher fatty acid material whic~ tends to substantlally reduce the effect of these compounds. The use of these sarcosine compounds in dentifrice compositions of the present invention is particularly advantageous since these materials exhibit a prolonged and marked effect in the inhibition of acid formation in the oral cavity due to carbohydrates bre~kdown in addition to exerting some reduction in the solubility of tooth enamel in acid solution.
Cationic surface active germicides and antibacterial com-pounds such as di-isobutylphenoxyethoxyetllyl dimethyl benzyl ammonium chloride, benzyl dimethyl stearyl ammonium chloride, tertiary amines having one fatty alkyl group (of from 12-18 carbon atoms) and two (poly) oxyethylene group~ attached to the nitrogen (typically containing a total of from about 2 to 50 ethanoxy groups per molecule) and salts thereof with acids, and -~ 1~1791 and compounds of the structure.

(~1~12CH20) 1~ /(C112C1120)"11 R-N-CH2CH2CH2N (cH2cH2o)yH .

where R is a fatty alkyl group containing from about 12 to 18 carbon atoms, and x, y and z total 3 or higher, as well as salts thereof with mineral or organic acids, may also be used. It is preferred to use from about 0.05 to 5% by welght of the foregoing surface-active materials in the instant dentifrlce.
An alkali metal fluorine-providing compound may be employed in the dentifrice of the invention. The alkali metal fluorine-providing compound includes-sodium fluorlde, potassium fluoride, lithium fluoride, ammonium fluoride and complex fluorldes, par-ticularly alkali metal monofluorophosphates. These compounds I exhibit satisfactory retentions of soluble fluoride in denti-fri.ces of the instant invention. In particular, the level of retention of monofluorophosphate ion as fluoride with the alkali metal monofluarophosphates is quite high. The fluorine-containing compound is employed in amount which provides an effective non-toxic amount of fluorine-containing ion to the dentlfrice typicall ab~ut 0.01-1% by weight pre$erably about 0.1% fluorine. Thus, sodium fluoride i~ typically employed in-amount of about 0.02-2%
by weight, preferably about 0.7%, and sodium monofluorophosphate, Na2P03F, in amount of about 0,1-7.6% by weight, preferably about 0.76%.
The alkali metal monofluorophosphates which may be employed include sodium monofluorophosphate, lithium monofluorophosphate, potassium monofluorophosphate and ammonium monofluorophoisphate.
The preferred salt is sodlum monofluorophosphate, Na2P03F, whicl . ' ,. Il ~ i -10- ,- i .j j . .

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119179~ 1 ..
.
as commercially avallable, may vary considerably in purity. It may be used in any suitable purity provided that any impurities do not substantially adversely affect the desired properties. In general, the purity is desirably at lease about 80%. For best results, it should be at least 85%, and preferably at least 9070 by weight of sodium monofluorophosphate with the balance being primarily impuritiPs or by-products of manufacture such as sodium ¦
fluoride, water;soluble sodium phosphate salt, and the like. I
Expressed in another way, the sodium monofluorophosphate employed¦
should ~a~e a tot~l fluorlde content of above 12%9 preferably 12.7%; a content of not more than 1.5%, preferably not more than ¦
1.2% of free sodium fluoride; and a sodium monofluorophosphate conl-tent of at least 12%, preferably at least 12.1%, all calculated as fluorine.
Other monofluorophosphate salts which may be used in the instant invention include monofluoropolyphosphates such as Na4P309F, K4P309F, (NH4)4P30gF, Na3KP309F, (NH4)3NaP30gF and Li4P30gF-. I

:.~ . . I

~ ~ l 1~L9~7~1 Antibacterial agents may also be employed in the oral pre-parations of tlle instant invention to provlde a total content of such agents of up to about 5~ by welght. Typical antibacterial agents lnclude Nl-(4-chlorobenzyl)-N5-(2,4-dichlorobenzyl) blguanide;
p-chlorophenyl biguanlde;
4-chlorobenzyhydryl blguanide;
4-chlorobenzyhydrylguanylurea;
. N-3-lauroxypropyl-N5-p-chlorobenzylbiguanlde;

l-(lauryldimethylammonlum)-8-(p-chlorobenzyldlmethylammonlum) octane dichloride;
5,6-dichloro-2-gunnldinobcnzlmldnzole;
N -p-chlorophenyl blguDnldohcxanc;
. 1,6-bis~2-ethylhexyl blguanldo) hex~ne;
5-a=ino- , -bl~(Z-e ehy lhexyl)- 5-e ethylhctahy~r~pyr(ml~ c;
-.
.
.

l~
~ 791 .

and their non-toxic acid addltion fialts~
Synthetic finely divided pyrogenic silica such as those sold under the trademarks Cab 0-Sil M-5, Syloid 244, Syloid 266 and Aerosil D-200 may also be employed in amounts of about 1-5%
by weight to promote tbickening or gelling of the dentifrice.

The taste of the new compositions may be modified by employing suitable flavoring or sweeten$ng materials. Examples of suitable flavoring constituents include the flavoring oils, e.g. oils of spearmint, peppermint, wintergreen, sassafras, clove9 sage, eucalyptus, marJoram, cinnamon, lemon and orange as well as methylsalicylate. Suitable sweetening ager.ts include sucrose, lactose, maltose, sorbitol, sodium cyclamate, perlllartine, and saccharine. Suitable flavor agent may comprise from about 0.01 to 5% or more of the compositions particularly when anionic surface active agent is present ~n the instant invention.
Various other materials may be incorporated in the dentifric formulations of this invention. Examples thereof are coloring or whitening agents or dyestuffs, preservatives, silicones, chloro-phyll compounds, ammoniated materials such as urea, diammonium-phosphate and mlxtures thereof, and other constituents. Thcse ad~uvants are incorporated in the instant compositlons in amounts which do not substantially adversely effect the properties and characteristic6 are deslred and selected and used in proper amoun depending upon the partlcular type of~preparation involved.
'1`11~ 1 r r ~ 1 V ~ n ~ r~lc~ic~ f~-r ~ . A
~oderaeely acid to alkaline pH is preferred.

The following specific examples are further i]]ustrativ~-of the nature of the present invention but is understood that the in-vention is not limited thereto. Dentifrice formulations are pre-pared in the usual manner and provide in situ flocculation of the siliceous polishing material~ and all amounts and ` ~91'791 proportions are by weight except as otherwise indicated.

The following opacified gel dentifrices are prepared:
PARTS
A B
Maltitol (75% solution) 40.00 40.00 Sodium aluminosilicate ~silica containing about 1% combined alumina - Zeo 49B-Huber~ 18.00 18.00 Pluronic F 108 Block Copolymer 3.00 3.00 Xanthan 1.70 1.70 Polyox WSR 301 ~Union Carbide) 0.20 Titanium dioxide 0.40 0.40 Flavor 0.50 0.50 Sodium saccharin 0.20 0.20 Deionized water Q.S. T0 100 Q.S. T0 100 Polyox WSR-301 is available from Union Carbide Corp. as granules of water soluble poly(ethylene oxide) resin having a molecular weight of about 4,000,000 and a Brookfield viscosity of 1650-3850 cps. ~25C, spindle 1, speed 2 rpm) when in water at 1% by weight. Likewise, similar foam and feel is attained when other ; 10 water-soluble poly~ethylene oxide) resins available from Union Carbide Corp. as Polyox WSR-N-10, WSR-N-80, WSR-N-750, WSR-N-3000, WSR-205 and WSR 1105 replace Polyox WSR-301~ in different concen-trations. Polyox is a trademark.
Both dentifrices provide stable full-bodied foam with good mouth feel; the mouth feel of dentifrice A being particularly satisfactory.
When compared for ability to remove dental stain and in dentin abrasion, dentifrice A containing the Polyox material removes more stain with less dentin abrasion than dentifrice B, without Polyox material. In dentifrice A, flocculated particles of sodium alumino-silicate form in situ.

, Thc rcsults nrc n3 follows:

" rl.R('.l.~lT RADlOACTIVli.
DENTIFRIC~ STAIN Rl.~OVAI. DENTI~l Al~l~ASTON

In a stain removal test, sectlons of human dental enamel are etched with 0.1N~lCl for 2 minutes, rinsed wltil water, then wet with a dilute solutlon of stannous fluorlde, wiped dry, and finally exposed to a stream of hydro~cn sulfldc ~ns whi~ rcYiults ln the deposlelon of a brown deposit of stannous sulfldc. Thc amount of stain on the surface ls measured with a Gi3rdner Auto-matlc Color Dlfference meter. The surface is then brushed wlth a ~echanlcal br~shlng machine for 5 reciprocal strokes wlth a slurry of a dentlfrice and the residual staln measured with the meter. Finally, the stain which remains is completely removed wieh dental pumice and the reflectance of this surface is read.
The ability of a dentifrice to remove-the stain is expressed by the following equatlon.

Percent stain removed = (Rd500 strbkes ~ Rdinitial) loO

pumiced ~ Rdinitial where Rdinitlal, Rd500 strokes, and Rdpumlced are respcct1vely the re1ectance vslues me~sured on the inltially Yitained surfaces ~; after brushlng for 5'. seclprocnl strokes and after removing the resldual stnin by pumicing.
~he RDA values are obtained by a procedure base~ on a radio-i acti~e technlque descrlbed ln the llterature; Seookey, C. K. and Muhlcr, J. C., J. I)cntal Rcucnrcll ~7 524 -538 (19fiB); Hefferren,-J. J.,J. Denta ese~rch 55 56~-573 (1976).

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~ -- ~L9~791 ` EXANrLE 2 : The followln~ dQntlfrlces ~re prcpared:

PARTS .

MaltitDl (75% solution)40.00 40.00 Sodiu~ alumlnosll~cate (sllica con-taining combined about lZ combined alumlna-~eo 49B - Huber)18.00 18.00 Calcined alumina 5.00 S.00 . Pluronic F-108 3.00 3.00 : Xanthan 1.70 1.70 : Polyox WSR 301 t~nion Carbide~ 0.20 -- .

Titanium dioxide 0.40 0.40 Flavor 0.50 0.50 Sodium saccharin 0.10 0.10 : Deionized water ,Q.S. to 100 Q.S. to 100 .
Both dentifrices provide stable full-bodied foam with good mouth feel; the mouth feel of dentifrice A being particularly sa~isfactory.
The followlng stain removal and radioactlve dentin abrasion results were obtained with dentlfrices A and B, evidencing superiority for dentifrice A, cont~lnin~ tl)e Polyox matcrlDl wlth ~: ~ rc~ard to higher st~ln removal ~ltll simil~r dcntin. abr~s.ion.
. . .
~` DENTIFRICE PERCENT STAIN RE~IOVAL R~A

1~7 4 . , '' .
,' 1~ 1191791 The Eollowlng opaclfied gel dentlfrlccs are prepare~I:

EX~MPLES

Glycerlne 10.01~.0 Maltitol 15.015.0 Sodium aluminosilicate (silica combined with about 1%
combincd alumlaa) Zeo 49B
~luber) 18.0l~.n Pluronic 108 block copolymer -- 3.0 Sodlum lauryl sulfate 1.0 --Xanthan 2.02.0 Polyox WSR 301 0.20.2 Sodlum monofluorophosphate 0.76 0.76 Titanlum dioxide 0.40.4 Low menthol flavor -- 0~5 Peppermint oil flavor 0.5 -- ~
Sodium saccharin 0.2 -- j Color solution (lX5 0.05 0.05 Water Q.S. to 100 Q.S. to 100 The dentifrice of E~ample 3 wlth sodium lauryl sulfate has ¦
deslrable Eoam character. The dentifrlce of Example 4 also has very good stable full-bodied foam character even though no anlonic surface actlve ag`ent 18 employed. The foam remnlns I
throughout the oral cavity, wl~h deslr~ble mouth fecl, when thc ~entiErice i8 bru6lIe~ onto tlle teeth. Morcover, lt has no bltter note even though low menthol f-lavor is present and no sweetener l~ add~d. The dentlfrices have fine smooth ~exture and arpe~rnnc effectlvely remove staln and have acceptable dentin abrasion character. They contain flocculated particles of sodium alumino sllicate. ~ ;

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~l ll9~L791 : Although this invention ha~ been described wlth regnrd to ill~lstrative examples, it will be apparent to one ~killed in the art that variou~ modification~ may be made thereto which fall within its scope.

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Claims (6)

CLAIMS:

1. A dentifrice comprising about 20-80% by weight of a liquid humectant vehicle, about 5-50% by weight of a siliceous polishing material and about 0.05-5% by weight of a resinous poly(ethylene oxide), said dentifrice containing flocculated particles formed by said siliceous polishing material in the presence of said poly(ethylene oxide).

2. The dentifrice claimed in Claim 1 wherein said resinous poly(ethylene oxide) has a reduced viscosity of at least 0.5 as measured at a concentration of 0.2 gram of said poly(ethylene oxide) in 100 milliliters of acetonitrile at 30°C.

3. The dentifrice claimed in Claim 2 wherein said resinous poly(ethylene oxide) is present in amount of about 0.1-1.5% by weight.

4. The dentifrice claimed in Claim 1 wherein said siliceous polishing material is a complex alkali metal aluminosilicate having a refractive index of from 1.44 to 1.47.

5. The dentifrice claimed in Claim 4 wherein said alkali metal aluminosilicate is sodium aluminosilicate wherein silica is combined with about 0.1-3% alumina.

6. The dentifrice claimed in Claim 1 wherein said floccu-lated particles have an apparent particle size of about .44 to 177 microns.