CA1136293A - Autofluorogram and composition and method for making the same - Google Patents
Autofluorogram and composition and method for making the sameInfo
- Publication number
- CA1136293A CA1136293A CA000340095A CA340095A CA1136293A CA 1136293 A CA1136293 A CA 1136293A CA 000340095 A CA000340095 A CA 000340095A CA 340095 A CA340095 A CA 340095A CA 1136293 A CA1136293 A CA 1136293A
- Authority
- CA
- Canada
- Prior art keywords
- fluor
- weight
- medium
- solvent
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims abstract description 55
- 239000000203 mixture Substances 0.000 title claims abstract description 33
- 239000002904 solvent Substances 0.000 claims abstract description 57
- 230000002285 radioactive effect Effects 0.000 claims abstract description 35
- 238000000926 separation method Methods 0.000 claims abstract description 21
- 230000000694 effects Effects 0.000 claims abstract description 7
- 238000004519 manufacturing process Methods 0.000 claims abstract description 4
- 230000002708 enhancing effect Effects 0.000 claims abstract 2
- 230000008961 swelling Effects 0.000 claims description 36
- 239000003112 inhibitor Substances 0.000 claims description 28
- CNRNYORZJGVOSY-UHFFFAOYSA-N 2,5-diphenyl-1,3-oxazole Chemical group C=1N=C(C=2C=CC=CC=2)OC=1C1=CC=CC=C1 CNRNYORZJGVOSY-UHFFFAOYSA-N 0.000 claims description 23
- QIMMUPPBPVKWKM-UHFFFAOYSA-N beta-methyl-naphthalene Natural products C1=CC=CC2=CC(C)=CC=C21 QIMMUPPBPVKWKM-UHFFFAOYSA-N 0.000 claims description 17
- 239000002250 absorbent Substances 0.000 claims description 15
- 230000002745 absorbent Effects 0.000 claims description 15
- 239000003463 adsorbent Substances 0.000 claims description 15
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 14
- 150000001735 carboxylic acids Chemical class 0.000 claims description 13
- 229920002401 polyacrylamide Polymers 0.000 claims description 12
- 241001465754 Metazoa Species 0.000 claims description 11
- 229920000936 Agarose Polymers 0.000 claims description 8
- 238000000151 deposition Methods 0.000 claims description 7
- 238000005470 impregnation Methods 0.000 claims description 7
- 239000007787 solid Substances 0.000 claims description 7
- 230000008021 deposition Effects 0.000 claims description 6
- -1 alkyl carboxylic acid Chemical class 0.000 claims description 5
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical group CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 claims description 4
- 229940093475 2-ethoxyethanol Drugs 0.000 claims description 3
- 239000002609 medium Substances 0.000 claims 24
- 239000012736 aqueous medium Substances 0.000 claims 3
- QIMMUPPBPVKWKM-RHRFEJLCSA-N 2-methylnaphthalene Chemical group C1=CC=[14CH]C2=CC(C)=CC=C21 QIMMUPPBPVKWKM-RHRFEJLCSA-N 0.000 claims 2
- 230000001376 precipitating effect Effects 0.000 claims 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract description 29
- YZCKVEUIGOORGS-NJFSPNSNSA-N Tritium Chemical compound [3H] YZCKVEUIGOORGS-NJFSPNSNSA-N 0.000 abstract description 9
- 229910052722 tritium Inorganic materials 0.000 abstract description 9
- OKTJSMMVPCPJKN-NJFSPNSNSA-N Carbon-14 Chemical compound [14C] OKTJSMMVPCPJKN-NJFSPNSNSA-N 0.000 abstract description 4
- 239000000499 gel Substances 0.000 description 49
- 239000000243 solution Substances 0.000 description 33
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 15
- 238000001962 electrophoresis Methods 0.000 description 13
- 206010056740 Genital discharge Diseases 0.000 description 12
- 239000012857 radioactive material Substances 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- 102000004169 proteins and genes Human genes 0.000 description 10
- 108090000623 proteins and genes Proteins 0.000 description 10
- 150000001875 compounds Chemical group 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 239000002245 particle Substances 0.000 description 7
- 230000005855 radiation Effects 0.000 description 7
- 238000002791 soaking Methods 0.000 description 7
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 238000000376 autoradiography Methods 0.000 description 5
- 238000004809 thin layer chromatography Methods 0.000 description 5
- 239000003963 antioxidant agent Substances 0.000 description 4
- 230000003078 antioxidant effect Effects 0.000 description 4
- 239000000839 emulsion Substances 0.000 description 4
- 238000012546 transfer Methods 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 229960000583 acetic acid Drugs 0.000 description 3
- 125000000217 alkyl group Chemical group 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 230000005284 excitation Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- QKLPIYTUUFFRLV-YTEMWHBBSA-N 1,4-bis[(e)-2-(2-methylphenyl)ethenyl]benzene Chemical compound CC1=CC=CC=C1\C=C\C(C=C1)=CC=C1\C=C\C1=CC=CC=C1C QKLPIYTUUFFRLV-YTEMWHBBSA-N 0.000 description 2
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- MASVCBBIUQRUKL-UHFFFAOYSA-N POPOP Chemical compound C=1N=C(C=2C=CC(=CC=2)C=2OC(=CN=2)C=2C=CC=CC=2)OC=1C1=CC=CC=C1 MASVCBBIUQRUKL-UHFFFAOYSA-N 0.000 description 2
- 239000011543 agarose gel Substances 0.000 description 2
- 125000003545 alkoxy group Chemical group 0.000 description 2
- MWPLVEDNUUSJAV-UHFFFAOYSA-N anthracene Chemical compound C1=CC=CC2=CC3=CC=CC=C3C=C21 MWPLVEDNUUSJAV-UHFFFAOYSA-N 0.000 description 2
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 2
- 229940095259 butylated hydroxytoluene Drugs 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 238000007598 dipping method Methods 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- NIHNNTQXNPWCJQ-UHFFFAOYSA-N fluorene Chemical compound C1=CC=C2CC3=CC=CC=C3C2=C1 NIHNNTQXNPWCJQ-UHFFFAOYSA-N 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 235000019645 odor Nutrition 0.000 description 2
- 150000002894 organic compounds Chemical class 0.000 description 2
- 239000002985 plastic film Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- OURODNXVJUWPMZ-UHFFFAOYSA-N 1,2-diphenylanthracene Chemical compound C1=CC=CC=C1C1=CC=C(C=C2C(C=CC=C2)=C2)C2=C1C1=CC=CC=C1 OURODNXVJUWPMZ-UHFFFAOYSA-N 0.000 description 1
- HTMCFKAMDSLHOX-UHFFFAOYSA-N 4-(2-butyl-6-phenylphenyl)-5-phenyloxadiazole Chemical compound C(CCC)C=1C(=C(C=CC=1)C1=CC=CC=C1)C=1N=NOC=1C1=CC=CC=C1 HTMCFKAMDSLHOX-UHFFFAOYSA-N 0.000 description 1
- YPYPBEGIASEWKA-UHFFFAOYSA-N 5-phenyl-1,3-oxazole Chemical compound O1C=NC=C1C1=CC=CC=C1 YPYPBEGIASEWKA-UHFFFAOYSA-N 0.000 description 1
- NIASZIRTUAIZRC-UHFFFAOYSA-N 5-phenyl-4-(2-phenyl-6-propan-2-ylphenyl)oxadiazole Chemical compound C(C)(C)C=1C(=C(C=CC=1)C1=CC=CC=C1)C=1N=NOC=1C1=CC=CC=C1 NIASZIRTUAIZRC-UHFFFAOYSA-N 0.000 description 1
- 229920002799 BoPET Polymers 0.000 description 1
- 241000518994 Conta Species 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 241000896693 Disa Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 241000701109 Human adenovirus 2 Species 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 1
- 239000005041 Mylar™ Substances 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 1
- NINIDFKCEFEMDL-AKLPVKDBSA-N Sulfur-35 Chemical compound [35S] NINIDFKCEFEMDL-AKLPVKDBSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 244000245420 ail Species 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 235000010290 biphenyl Nutrition 0.000 description 1
- 239000004305 biphenyl Substances 0.000 description 1
- JRXXLCKWQFKACW-UHFFFAOYSA-N biphenylacetylene Chemical group C1=CC=CC=C1C#CC1=CC=CC=C1 JRXXLCKWQFKACW-UHFFFAOYSA-N 0.000 description 1
- XZCJVWCMJYNSQO-UHFFFAOYSA-N butyl pbd Chemical compound C1=CC(C(C)(C)C)=CC=C1C1=NN=C(C=2C=CC(=CC=2)C=2C=CC=CC=2)O1 XZCJVWCMJYNSQO-UHFFFAOYSA-N 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000004611 garlic Nutrition 0.000 description 1
- 238000001502 gel electrophoresis Methods 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000005567 liquid scintillation counting Methods 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 229940057952 methanol Drugs 0.000 description 1
- YERRTOUSFSZICJ-UHFFFAOYSA-N methyl 2-amino-2-(4-bromophenyl)acetate Chemical compound COC(=O)C(N)C1=CC=C(Br)C=C1 YERRTOUSFSZICJ-UHFFFAOYSA-N 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- GWUSZQUVEVMBPI-UHFFFAOYSA-N nimetazepam Chemical compound N=1CC(=O)N(C)C2=CC=C([N+]([O-])=O)C=C2C=1C1=CC=CC=C1 GWUSZQUVEVMBPI-UHFFFAOYSA-N 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000001995 reticulocyte Anatomy 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- CMXPERZAMAQXSF-UHFFFAOYSA-M sodium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate;1,8-dihydroxyanthracene-9,10-dione Chemical compound [Na+].O=C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O.CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC CMXPERZAMAQXSF-UHFFFAOYSA-M 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/16—Measuring radiation intensity
- G01T1/20—Measuring radiation intensity with scintillation detectors
- G01T1/204—Measuring radiation intensity with scintillation detectors the detector being a liquid
- G01T1/2042—Composition for liquid scintillation systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/29—Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
- G01T1/2914—Measurement of spatial distribution of radiation
- G01T1/2921—Static instruments for imaging the distribution of radioactivity in one or two dimensions; Radio-isotope cameras
- G01T1/2942—Static instruments for imaging the distribution of radioactivity in one or two dimensions; Radio-isotope cameras using autoradiographic methods
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Spectroscopy & Molecular Physics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- High Energy & Nuclear Physics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Measurement Of Radiation (AREA)
- Luminescent Compositions (AREA)
- Conversion Of X-Rays Into Visible Images (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25,653 | 1979-03-30 | ||
| US06/025,653 US4293436A (en) | 1979-03-30 | 1979-03-30 | Autofluorogram and composition and method for making the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1136293A true CA1136293A (en) | 1982-11-23 |
Family
ID=21827302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000340095A Expired CA1136293A (en) | 1979-03-30 | 1979-11-19 | Autofluorogram and composition and method for making the same |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4293436A (OSRAM) |
| JP (1) | JPS55152779A (OSRAM) |
| AT (1) | AT368290B (OSRAM) |
| BE (1) | BE881400A (OSRAM) |
| CA (1) | CA1136293A (OSRAM) |
| CH (1) | CH649844A5 (OSRAM) |
| DE (1) | DE3007132C2 (OSRAM) |
| FR (1) | FR2452713A1 (OSRAM) |
| GB (1) | GB2046290B (OSRAM) |
| NL (1) | NL8000755A (OSRAM) |
| SE (1) | SE444230B (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4562158A (en) * | 1981-07-27 | 1985-12-31 | Eastern Virginia Medical Authority | Solid phase scintillation counting method |
| US4522742A (en) * | 1982-02-25 | 1985-06-11 | E. I. Du Pont De Nemours And Company Inc. | Water soluble fluor compositions |
| US4510392A (en) * | 1983-04-08 | 1985-04-09 | E. I. Du Pont De Nemours And Company | Autoradiogram marking process |
| US4626513A (en) * | 1983-11-10 | 1986-12-02 | Massachusetts General Hospital | Method and apparatus for ligand detection |
| GB8403128D0 (en) * | 1984-02-07 | 1984-03-14 | Amersham Int Plc | Standard for analysis |
| US4692266A (en) * | 1985-08-16 | 1987-09-08 | Eastman Kodak Company | Solid scintillator counting compositions |
| US4710319A (en) * | 1985-11-08 | 1987-12-01 | E. I. Du Pont De Nemours And Company | Autofluorogram composition |
| US4769334A (en) * | 1986-02-12 | 1988-09-06 | Linus Pauling Institute Of Science And Medicine | Method for detecting proteins in gels using radioactive dyes |
| US4916320A (en) * | 1987-08-24 | 1990-04-10 | Beckman Instruments, Inc. | Sample counting support with solid scintillator for use in scintillation counting |
| US4871480A (en) * | 1987-11-24 | 1989-10-03 | Electron Microscope Supplies Corporation | Audoradiography enhancer and method of use |
| US5011781A (en) * | 1987-11-24 | 1991-04-30 | Electron Microscope Supplies Corporation | Autoradiography enhancer and method of use |
| US5051596A (en) * | 1990-07-05 | 1991-09-24 | Brandeis University | Autography marking tape |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB770889A (en) * | 1952-01-10 | 1957-03-27 | American Cyanamid Co | Improvements relating to fluorescent pigments |
| US3928227A (en) * | 1967-02-01 | 1975-12-23 | Sentol Associates | Liquid scintillation, counting and compositions |
| US3999070A (en) * | 1972-04-10 | 1976-12-21 | Packard Instrument Company, Inc. | Composition for use in scintillator systems |
-
1979
- 1979-03-30 US US06/025,653 patent/US4293436A/en not_active Expired - Lifetime
- 1979-11-19 CA CA000340095A patent/CA1136293A/en not_active Expired
-
1980
- 1980-01-09 SE SE8000180A patent/SE444230B/sv not_active IP Right Cessation
- 1980-01-16 GB GB8001436A patent/GB2046290B/en not_active Expired
- 1980-01-29 BE BE0/199149A patent/BE881400A/fr not_active IP Right Cessation
- 1980-01-30 CH CH746/80A patent/CH649844A5/de not_active IP Right Cessation
- 1980-02-07 NL NL8000755A patent/NL8000755A/nl not_active Application Discontinuation
- 1980-02-21 FR FR8003777A patent/FR2452713A1/fr active Granted
- 1980-02-26 DE DE3007132A patent/DE3007132C2/de not_active Expired
- 1980-02-27 AT AT0108080A patent/AT368290B/de not_active IP Right Cessation
- 1980-03-31 JP JP4193380A patent/JPS55152779A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS55152779A (en) | 1980-11-28 |
| NL8000755A (nl) | 1980-10-02 |
| SE444230B (sv) | 1986-03-24 |
| DE3007132A1 (de) | 1980-10-02 |
| GB2046290B (en) | 1983-04-20 |
| ATA108080A (de) | 1982-01-15 |
| BE881400A (fr) | 1980-05-16 |
| FR2452713A1 (fr) | 1980-10-24 |
| CH649844A5 (de) | 1985-06-14 |
| GB2046290A (en) | 1980-11-12 |
| JPH0122316B2 (OSRAM) | 1989-04-26 |
| DE3007132C2 (de) | 1984-05-17 |
| US4293436A (en) | 1981-10-06 |
| SE8000180L (sv) | 1980-10-01 |
| FR2452713B1 (OSRAM) | 1985-05-10 |
| AT368290B (de) | 1982-09-27 |
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