CA1127490A - Blood oxygenator - Google Patents
Blood oxygenatorInfo
- Publication number
- CA1127490A CA1127490A CA298,421A CA298421A CA1127490A CA 1127490 A CA1127490 A CA 1127490A CA 298421 A CA298421 A CA 298421A CA 1127490 A CA1127490 A CA 1127490A
- Authority
- CA
- Canada
- Prior art keywords
- blood
- water
- flow
- units
- oxygen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 300
- 239000008280 blood Substances 0.000 title claims abstract description 300
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 257
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 167
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 94
- 239000001301 oxygen Substances 0.000 claims abstract description 93
- 239000012528 membrane Substances 0.000 claims abstract description 49
- 238000009792 diffusion process Methods 0.000 claims abstract description 4
- 125000006850 spacer group Chemical group 0.000 claims description 21
- 239000012530 fluid Substances 0.000 claims description 14
- 238000004891 communication Methods 0.000 claims description 11
- 230000017531 blood circulation Effects 0.000 claims description 8
- 230000004087 circulation Effects 0.000 claims description 2
- 230000037361 pathway Effects 0.000 claims 6
- 230000004888 barrier function Effects 0.000 claims 1
- 238000010276 construction Methods 0.000 abstract description 22
- 239000007789 gas Substances 0.000 abstract description 17
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract description 10
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract description 5
- 239000001569 carbon dioxide Substances 0.000 abstract description 5
- 239000007788 liquid Substances 0.000 abstract description 2
- 150000002605 large molecules Chemical class 0.000 abstract 1
- 229920002521 macromolecule Polymers 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 16
- 239000000463 material Substances 0.000 description 16
- -1 polypropylene Polymers 0.000 description 9
- 239000004743 Polypropylene Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 229920001155 polypropylene Polymers 0.000 description 5
- 239000004698 Polyethylene Substances 0.000 description 4
- 239000012153 distilled water Substances 0.000 description 4
- 229920000573 polyethylene Polymers 0.000 description 4
- 210000002105 tongue Anatomy 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 239000003054 catalyst Substances 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- 239000004809 Teflon Substances 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 210000001772 blood platelet Anatomy 0.000 description 2
- 230000005465 channeling Effects 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 229910001882 dioxygen Inorganic materials 0.000 description 2
- 210000005069 ears Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000037452 priming Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000012414 sterilization procedure Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 239000004925 Acrylic resin Substances 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- CEJLBZWIKQJOAT-UHFFFAOYSA-N dichloroisocyanuric acid Chemical compound ClN1C(=O)NC(=O)N(Cl)C1=O CEJLBZWIKQJOAT-UHFFFAOYSA-N 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 210000004779 membrane envelope Anatomy 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/089—Modules where the membrane is in the form of a bag, membrane cushion or pad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/24—Specific pressurizing or depressurizing means
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/774,675 US4168293A (en) | 1977-03-07 | 1977-03-07 | Blood oxygenator |
| US774,675 | 1977-03-07 | ||
| US88103778A | 1978-02-24 | 1978-02-24 | |
| US881,037 | 1978-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1127490A true CA1127490A (en) | 1982-07-13 |
Family
ID=27118938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA298,421A Expired CA1127490A (en) | 1977-03-07 | 1978-03-07 | Blood oxygenator |
Country Status (7)
| Country | Link |
|---|---|
| BR (1) | BR7801375A (pt) |
| CA (1) | CA1127490A (pt) |
| DE (1) | DE2809516A1 (pt) |
| FR (1) | FR2382899A1 (pt) |
| GB (1) | GB1598149A (pt) |
| IL (1) | IL54202A0 (pt) |
| IT (1) | IT1110463B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2911508A1 (de) * | 1978-03-28 | 1979-10-04 | Kuraray Co | Fluidbehandlungsvorrichtung |
| FR2478482A1 (fr) * | 1980-03-21 | 1981-09-25 | Lidorenko Nikolai | Membrane permeable aux gaz, procede de fabrication de celle-ci et oxygenateur de sang utilisant ladite membrane |
| FR2482055B1 (fr) * | 1980-05-08 | 1985-10-04 | Sodip Sa | Dispositif formant enveloppe pour un empilement, appareil comportant ledit dispositif et procede de montage d'un tel appareil |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3135538A (en) * | 1959-05-18 | 1964-06-02 | Chemetron Corp | Flanged pipe joint having one flange deflectable |
| US3219573A (en) * | 1959-10-15 | 1965-11-23 | American Mach & Foundry | Multiple chamber electrodialysis apparatus |
| US3332746A (en) * | 1963-03-29 | 1967-07-25 | Single Cell Res Foundation Inc | Pulsatile membrane oxygenator apparatus |
| US3540595A (en) * | 1965-05-18 | 1970-11-17 | Miles Lowell Edwards | Membrane fluid diffusion exchange device |
| US3413095A (en) * | 1965-06-14 | 1968-11-26 | Mogens L. Bramson | Membrane oxygenator |
| US3370710A (en) * | 1966-05-11 | 1968-02-27 | Research Corp | Compact blood dialyzer with a pleated membrane therein |
| DE1792446A1 (de) * | 1968-09-04 | 1971-04-29 | Josef Dr Med Hoeltzenbein | Dialysator aus gestapelten Membranen |
| US3834544A (en) * | 1971-07-06 | 1974-09-10 | Cutter Lab | Membrane diffusion apparatus |
| US3839204A (en) * | 1972-04-27 | 1974-10-01 | Gen Electric | Integral blood heat and component exchange device and two flow path membrane blood gas exchanger |
| FR2206110B1 (pt) * | 1972-11-14 | 1976-04-23 | Rhone Poulenc Ind | |
| FR2346616A1 (fr) * | 1976-04-02 | 1977-10-28 | Rhone Poulenc Ind | Procede pour realiser l'etancheite d'un appareil a membrane |
-
1978
- 1978-03-02 GB GB8369/78A patent/GB1598149A/en not_active Expired
- 1978-03-06 DE DE19782809516 patent/DE2809516A1/de not_active Ceased
- 1978-03-06 IL IL54202A patent/IL54202A0/xx not_active IP Right Cessation
- 1978-03-07 FR FR7806496A patent/FR2382899A1/fr active Granted
- 1978-03-07 CA CA298,421A patent/CA1127490A/en not_active Expired
- 1978-03-07 IT IT20955/78A patent/IT1110463B/it active
- 1978-03-07 BR BR7801375A patent/BR7801375A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR7801375A (pt) | 1978-09-26 |
| GB1598149A (en) | 1981-09-16 |
| IT7820955A0 (it) | 1978-03-07 |
| DE2809516A1 (de) | 1979-09-06 |
| FR2382899A1 (fr) | 1978-10-06 |
| IL54202A0 (en) | 1978-06-15 |
| FR2382899B1 (pt) | 1985-04-05 |
| IT1110463B (it) | 1985-12-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3834544A (en) | Membrane diffusion apparatus | |
| US3839204A (en) | Integral blood heat and component exchange device and two flow path membrane blood gas exchanger | |
| US4411872A (en) | Water unit for use with a membrane blood oxygenator | |
| US3976576A (en) | Dialyzer cartridge | |
| US3332746A (en) | Pulsatile membrane oxygenator apparatus | |
| US3585131A (en) | Pleated memberane exchange device | |
| US3413095A (en) | Membrane oxygenator | |
| US4176069A (en) | Device for exchanging substances and method of manufacturing the device | |
| GB2080144A (en) | Membrane separating device | |
| US3907687A (en) | Plate dialyzer | |
| US3540595A (en) | Membrane fluid diffusion exchange device | |
| US4016081A (en) | Staged membrane diffusion device and membrane support | |
| US4256692A (en) | Membrane oxygenator | |
| US3757955A (en) | Multi-layer membrane type mass transfer device and process | |
| US3541595A (en) | Membrane fluid diffusion exchange device | |
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| US3910841A (en) | Stacked exchange device | |
| US3266629A (en) | Gas and liquid exchange apparatus | |
| US3879293A (en) | Membrane diffusion device having inflatable member for pressurization and sealing | |
| US4318813A (en) | Membrane plasmapheresis module | |
| EP0301022B1 (en) | Apparatus for exchanging ions, molecules, gas, liquid and/or heat between fluids | |
| CA1127490A (en) | Blood oxygenator | |
| US4168293A (en) | Blood oxygenator | |
| US3464562A (en) | Dialyzing apparatus and method of making the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |