CA1108173A - Stable liquid antimony organic sulfur-containing compounds - Google Patents
Stable liquid antimony organic sulfur-containing compoundsInfo
- Publication number
- CA1108173A CA1108173A CA305,116A CA305116A CA1108173A CA 1108173 A CA1108173 A CA 1108173A CA 305116 A CA305116 A CA 305116A CA 1108173 A CA1108173 A CA 1108173A
- Authority
- CA
- Canada
- Prior art keywords
- antimony
- alkyl
- group
- phenol
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052787 antimony Inorganic materials 0.000 title claims abstract description 57
- 239000007788 liquid Substances 0.000 title claims abstract description 37
- 150000001875 compounds Chemical class 0.000 title claims abstract description 32
- WATWJIUSRGPENY-UHFFFAOYSA-N antimony atom Chemical compound [Sb] WATWJIUSRGPENY-UHFFFAOYSA-N 0.000 claims abstract description 49
- 239000000203 mixture Substances 0.000 claims abstract description 27
- -1 vinyl halide Chemical class 0.000 claims abstract description 27
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims abstract description 25
- 150000002989 phenols Chemical class 0.000 claims abstract description 25
- 235000019282 butylated hydroxyanisole Nutrition 0.000 claims abstract description 10
- 239000004255 Butylated hydroxyanisole Substances 0.000 claims abstract description 9
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229940043253 butylated hydroxyanisole Drugs 0.000 claims abstract description 9
- 125000003118 aryl group Chemical group 0.000 claims description 27
- 125000000217 alkyl group Chemical group 0.000 claims description 23
- 150000001463 antimony compounds Chemical class 0.000 claims description 16
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 16
- 239000007983 Tris buffer Substances 0.000 claims description 9
- 125000003342 alkenyl group Chemical group 0.000 claims description 7
- 125000000304 alkynyl group Chemical group 0.000 claims description 6
- 125000000732 arylene group Chemical group 0.000 claims description 5
- 125000000392 cycloalkenyl group Chemical group 0.000 claims description 5
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 5
- 239000003381 stabilizer Substances 0.000 claims description 5
- 229910052717 sulfur Inorganic materials 0.000 claims description 5
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 claims description 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 4
- 125000003545 alkoxy group Chemical group 0.000 claims description 4
- 125000002947 alkylene group Chemical group 0.000 claims description 4
- 239000011593 sulfur Substances 0.000 claims description 4
- IUNVCWLKOOCPIT-UHFFFAOYSA-N 6-methylheptylsulfanyl 2-hydroxyacetate Chemical compound CC(C)CCCCCSOC(=O)CO IUNVCWLKOOCPIT-UHFFFAOYSA-N 0.000 claims description 3
- 125000002877 alkyl aryl group Chemical group 0.000 claims description 3
- 125000004104 aryloxy group Chemical group 0.000 claims description 3
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 claims description 3
- SRUQARLMFOLRDN-UHFFFAOYSA-N 1-(2,4,5-Trihydroxyphenyl)-1-butanone Chemical compound CCCC(=O)C1=CC(O)=C(O)C=C1O SRUQARLMFOLRDN-UHFFFAOYSA-N 0.000 claims description 2
- HXIQYSLFEXIOAV-UHFFFAOYSA-N 2-tert-butyl-4-(5-tert-butyl-4-hydroxy-2-methylphenyl)sulfanyl-5-methylphenol Chemical compound CC1=CC(O)=C(C(C)(C)C)C=C1SC1=CC(C(C)(C)C)=C(O)C=C1C HXIQYSLFEXIOAV-UHFFFAOYSA-N 0.000 claims description 2
- 239000000470 constituent Substances 0.000 claims description 2
- MIHINWMALJZIBX-UHFFFAOYSA-N cyclohexa-2,4-dien-1-ol Chemical class OC1CC=CC=C1 MIHINWMALJZIBX-UHFFFAOYSA-N 0.000 claims description 2
- GDESWOTWNNGOMW-UHFFFAOYSA-N resorcinol monobenzoate Chemical compound OC1=CC=CC(OC(=O)C=2C=CC=CC=2)=C1 GDESWOTWNNGOMW-UHFFFAOYSA-N 0.000 claims description 2
- 125000000547 substituted alkyl group Chemical group 0.000 claims description 2
- 235000013350 formula milk Nutrition 0.000 claims 6
- PSYGHMBJXWRQFD-UHFFFAOYSA-N 2-(2-sulfanylacetyl)oxyethyl 2-sulfanylacetate Chemical compound SCC(=O)OCCOC(=O)CS PSYGHMBJXWRQFD-UHFFFAOYSA-N 0.000 claims 2
- OATORLCCIQBWBF-UHFFFAOYSA-K 6-methylheptyl 2-bis[[2-(6-methylheptoxy)-2-oxoethyl]sulfanyl]stibanylsulfanylacetate Chemical compound [Sb+3].CC(C)CCCCCOC(=O)C[S-].CC(C)CCCCCOC(=O)C[S-].CC(C)CCCCCOC(=O)C[S-] OATORLCCIQBWBF-UHFFFAOYSA-K 0.000 claims 2
- ORDRGXFSRBRQQG-UHFFFAOYSA-N 6-methylheptyl 2-sulfanylpropanoate Chemical compound CC(C)CCCCCOC(=O)C(C)S ORDRGXFSRBRQQG-UHFFFAOYSA-N 0.000 claims 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 claims 2
- HZDVLBNBEOISNW-UHFFFAOYSA-M dodecylsulfanylantimony Chemical compound CCCCCCCCCCCCS[Sb] HZDVLBNBEOISNW-UHFFFAOYSA-M 0.000 claims 2
- TXPYHRFTMYVSLD-UHFFFAOYSA-N 2,3,4-tris(2-methylpropyl)phenol Chemical compound CC(C)CC1=CC=C(O)C(CC(C)C)=C1CC(C)C TXPYHRFTMYVSLD-UHFFFAOYSA-N 0.000 claims 1
- XKASSKVHKRFUFX-UHFFFAOYSA-N 2,3,4-tris(6-methylheptyl)phenol Chemical compound CC(C)CCCCCC1=CC=C(O)C(CCCCCC(C)C)=C1CCCCCC(C)C XKASSKVHKRFUFX-UHFFFAOYSA-N 0.000 claims 1
- STMRWVUTGPZZER-UHFFFAOYSA-N 2,3-bis(2-methylpropyl)phenol Chemical compound CC(C)CC1=CC=CC(O)=C1CC(C)C STMRWVUTGPZZER-UHFFFAOYSA-N 0.000 claims 1
- FNRRHKQTVNDRSJ-UHFFFAOYSA-N 2,3-bis(6-methylheptyl)phenol Chemical compound CC(C)CCCCCC1=CC=CC(O)=C1CCCCCC(C)C FNRRHKQTVNDRSJ-UHFFFAOYSA-N 0.000 claims 1
- PFANXOISJYKQRP-UHFFFAOYSA-N 2-tert-butyl-4-[1-(5-tert-butyl-4-hydroxy-2-methylphenyl)butyl]-5-methylphenol Chemical compound C=1C(C(C)(C)C)=C(O)C=C(C)C=1C(CCC)C1=CC(C(C)(C)C)=C(O)C=C1C PFANXOISJYKQRP-UHFFFAOYSA-N 0.000 claims 1
- GDEHXPCZWFXRKC-UHFFFAOYSA-N 4-(2-methylpropyl)phenol Chemical compound CC(C)CC1=CC=C(O)C=C1 GDEHXPCZWFXRKC-UHFFFAOYSA-N 0.000 claims 1
- HVXRCAWUNAOCTA-UHFFFAOYSA-N 4-(6-methylheptyl)phenol Chemical compound CC(C)CCCCCC1=CC=C(O)C=C1 HVXRCAWUNAOCTA-UHFFFAOYSA-N 0.000 claims 1
- 229960000969 phenyl salicylate Drugs 0.000 claims 1
- 239000001294 propane Substances 0.000 claims 1
- ZQBAKBUEJOMQEX-UHFFFAOYSA-N salicylic acid phenyl ester Natural products OC1=CC=CC=C1C(=O)OC1=CC=CC=C1 ZQBAKBUEJOMQEX-UHFFFAOYSA-N 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 abstract description 7
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 abstract description 6
- 150000002148 esters Chemical class 0.000 abstract description 6
- 239000011347 resin Substances 0.000 abstract description 6
- 229920005989 resin Polymers 0.000 abstract description 6
- JIGUICYYOYEXFS-UHFFFAOYSA-N 3-tert-butylbenzene-1,2-diol Chemical compound CC(C)(C)C1=CC=CC(O)=C1O JIGUICYYOYEXFS-UHFFFAOYSA-N 0.000 abstract description 3
- 229940075103 antimony Drugs 0.000 description 45
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- 229940058905 antimony compound for treatment of leishmaniasis and trypanosomiasis Drugs 0.000 description 5
- 239000000306 component Substances 0.000 description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Substances OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
- 230000006641 stabilisation Effects 0.000 description 4
- 238000011105 stabilization Methods 0.000 description 4
- 239000004215 Carbon black (E152) Substances 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 125000001931 aliphatic group Chemical group 0.000 description 3
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 3
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
- 230000006866 deterioration Effects 0.000 description 3
- WNAHIZMDSQCWRP-UHFFFAOYSA-N dodecane-1-thiol Chemical compound CCCCCCCCCCCCS WNAHIZMDSQCWRP-UHFFFAOYSA-N 0.000 description 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 3
- 229930195733 hydrocarbon Natural products 0.000 description 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 3
- YIWUKEYIRIRTPP-UHFFFAOYSA-N 2-ethylhexan-1-ol Chemical compound CCCCC(CC)CO YIWUKEYIRIRTPP-UHFFFAOYSA-N 0.000 description 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 2
- BJEMXPVDXFSROA-UHFFFAOYSA-N 3-butylbenzene-1,2-diol Chemical group CCCCC1=CC=CC(O)=C1O BJEMXPVDXFSROA-UHFFFAOYSA-N 0.000 description 2
- SXZDTYABFPAVOF-UHFFFAOYSA-N CCCC[Sb] Chemical compound CCCC[Sb] SXZDTYABFPAVOF-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical group C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 2
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- 150000002430 hydrocarbons Chemical group 0.000 description 2
- 150000002431 hydrogen Chemical class 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 2
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- JRNGUTKWMSBIBF-UHFFFAOYSA-N naphthalene-2,3-diol Chemical group C1=CC=C2C=C(O)C(O)=CC2=C1 JRNGUTKWMSBIBF-UHFFFAOYSA-N 0.000 description 2
- 125000000286 phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- 125000003396 thiol group Chemical class [H]S* 0.000 description 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 125000005023 xylyl group Chemical group 0.000 description 2
- LDVVMCZRFWMZSG-OLQVQODUSA-N (3ar,7as)-2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)Cl)C(=O)[C@H]21 LDVVMCZRFWMZSG-OLQVQODUSA-N 0.000 description 1
- VNFXPOAMRORRJJ-UHFFFAOYSA-N (4-octylphenyl) 2-hydroxybenzoate Chemical compound C1=CC(CCCCCCCC)=CC=C1OC(=O)C1=CC=CC=C1O VNFXPOAMRORRJJ-UHFFFAOYSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- QWUWMCYKGHVNAV-UHFFFAOYSA-N 1,2-dihydrostilbene Chemical group C=1C=CC=CC=1CCC1=CC=CC=C1 QWUWMCYKGHVNAV-UHFFFAOYSA-N 0.000 description 1
- 150000005206 1,2-dihydroxybenzenes Chemical class 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N 2-Ethylhexanoic acid Chemical compound CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- RFCQDOVPMUSZMN-UHFFFAOYSA-N 2-Naphthalenethiol Chemical compound C1=CC=CC2=CC(S)=CC=C21 RFCQDOVPMUSZMN-UHFFFAOYSA-N 0.000 description 1
- 125000004974 2-butenyl group Chemical group C(C=CC)* 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- REFZTFPICLNNPM-UHFFFAOYSA-N 2-sulfanyldodecanoic acid Chemical compound CCCCCCCCCCC(S)C(O)=O REFZTFPICLNNPM-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- XESZUVZBAMCAEJ-UHFFFAOYSA-N 4-tert-butylcatechol Chemical compound CC(C)(C)C1=CC=C(O)C(O)=C1 XESZUVZBAMCAEJ-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 101150034533 ATIC gene Proteins 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
- 239000005745 Captan Substances 0.000 description 1
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 1
- 101100126176 Escherichia coli (strain K12) intQ gene Proteins 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241001527806 Iti Species 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- IGFHQQFPSIBGKE-UHFFFAOYSA-N Nonylphenol Natural products CCCCCCCCCC1=CC=C(O)C=C1 IGFHQQFPSIBGKE-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- WDENQIQQYWYTPO-IBGZPJMESA-N acalabrutinib Chemical compound CC#CC(=O)N1CCC[C@H]1C1=NC(C=2C=CC(=CC=2)C(=O)NC=2N=CC=CC=2)=C2N1C=CN=C2N WDENQIQQYWYTPO-IBGZPJMESA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 125000004423 acyloxy group Chemical group 0.000 description 1
- 125000002723 alicyclic group Chemical group 0.000 description 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- UENWRTRMUIOCKN-UHFFFAOYSA-N benzyl thiol Chemical compound SCC1=CC=CC=C1 UENWRTRMUIOCKN-UHFFFAOYSA-N 0.000 description 1
- 235000010290 biphenyl Nutrition 0.000 description 1
- 239000004305 biphenyl Substances 0.000 description 1
- 125000006267 biphenyl group Chemical group 0.000 description 1
- DGAODIKUWGRDBO-UHFFFAOYSA-N butanethioic s-acid Chemical compound CCCC(O)=S DGAODIKUWGRDBO-UHFFFAOYSA-N 0.000 description 1
- 229940117949 captan Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001721 carbon Chemical group 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 125000000582 cycloheptyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 125000000640 cyclooctyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 description 1
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- KIAJFTQCDGDHFO-UHFFFAOYSA-N dibutylantimony Chemical compound CCCC[Sb]CCCC KIAJFTQCDGDHFO-UHFFFAOYSA-N 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical class COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 description 1
- 125000003187 heptyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000012943 hotmelt Substances 0.000 description 1
- 125000001145 hydrido group Chemical class *[H] 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 235000015250 liver sausages Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- NXPPAOGUKPJVDI-UHFFFAOYSA-N naphthalene-1,2-diol Chemical compound C1=CC=CC2=C(O)C(O)=CC=C21 NXPPAOGUKPJVDI-UHFFFAOYSA-N 0.000 description 1
- 150000002790 naphthalenes Chemical class 0.000 description 1
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 125000001741 organic sulfur group Chemical group 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 description 1
- YODZTKMDCQEPHD-UHFFFAOYSA-N thiodiglycol Chemical compound OCCSCCO YODZTKMDCQEPHD-UHFFFAOYSA-N 0.000 description 1
- 229940035024 thioglycerol Drugs 0.000 description 1
- 229940071127 thioglycolate Drugs 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- ZSDSQXJSNMTJDA-UHFFFAOYSA-N trifluralin Chemical compound CCCN(CCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O ZSDSQXJSNMTJDA-UHFFFAOYSA-N 0.000 description 1
- 125000002256 xylenyl group Chemical class C1(C(C=CC=C1)C)(C)* 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/90—Antimony compounds
- C07F9/902—Compounds without antimony-carbon linkages
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/59—Arsenic- or antimony-containing compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Abstract
Abstract of the Disclosure Liquid antimony organic sulfur-containing compounds are rendered stable at ambient conditions by incorporating an effec-tive amount of a phenol. Liquid antimony organic sulfur-con-taining compounds such as antimony mercaptoacid esters, and the like, are also rendered shelf stable by phenols such as catechol, t-butyl catechol and butylated hydroxy anisole. The stable liquid compositions contribute to the heat stability of vinyl halide resins.
Description
l'l(lt3~73 J:~rJ
Back-3roul1d of tl1c Invention . . .
~ ntimony mercaptides have been proposed a~ stabiliz~r~
for vinyl halide resins to guard again~t deg~adation by heat during molding and working of the re~in intQ u~e~ul a~ticle~.
Prior art patents which disclos~ such antimony organic ~ulur-containing compounds and thei~ utility as ~tabilize~ in~lude U.S. Patent No8. ~,680,726; 2,684,956; 3,340,28$1 3,399,2~0~
3,466,261 and 3,530,158. In pa~t comme~cial practice, ho~ever, the antimony mercaptide~ have not been ~idely u~cd ~ ~tabilizers because of various ~orcomlngg including, ~o~ exampl~, thei~
propensity to exude from molded or wo~ked ~v~ pla~tiç ~t~k, C08t or lack of other advan~ages a~sociat~d ~itb thQi~ u~e which migh~ outweigh uch 6hortcomiP~o~ ~y U,S. ~atcnt No. 3 1 ~7 ~ 50 i~ di~ected to i~provement8 ln th~ utill~atio~ qf antimon~ ~~
ganiC ~ul~ur-containing compound~ in combl~atlon ~itb metal car- :
boxylate~. A~ de~cribed in my U.S. pat~nt No. 3,qB7,5~B, the utility and efficiency of ~uch antlmony co~pound~ ar~ improved in the heat stabilization of vinyl halldc re6in~ to a~ unexpected degree. It has been observed, however, that ~uch antimony com-pound~ which are normally liquld tend to deteriorate or become unstable upon 6torage.
Summary of the Invention , '~
' :~ a. s . Patent 4,029,618 issued June 14, 1977 is directed to further improvements in vinyl halide resin sta-bilizer syfit~ms of antimony organic 6ul~ur-containing compounds.
The invention described therein in one of it6 aspects provided for synergi6tic heat 6tabilizer composition~ of antimony compounds afi stabilizers and ortho-dihydric phenols. In anothe~ of it~
Back-3roul1d of tl1c Invention . . .
~ ntimony mercaptides have been proposed a~ stabiliz~r~
for vinyl halide resins to guard again~t deg~adation by heat during molding and working of the re~in intQ u~e~ul a~ticle~.
Prior art patents which disclos~ such antimony organic ~ulur-containing compounds and thei~ utility as ~tabilize~ in~lude U.S. Patent No8. ~,680,726; 2,684,956; 3,340,28$1 3,399,2~0~
3,466,261 and 3,530,158. In pa~t comme~cial practice, ho~ever, the antimony mercaptide~ have not been ~idely u~cd ~ ~tabilizers because of various ~orcomlngg including, ~o~ exampl~, thei~
propensity to exude from molded or wo~ked ~v~ pla~tiç ~t~k, C08t or lack of other advan~ages a~sociat~d ~itb thQi~ u~e which migh~ outweigh uch 6hortcomiP~o~ ~y U,S. ~atcnt No. 3 1 ~7 ~ 50 i~ di~ected to i~provement8 ln th~ utill~atio~ qf antimon~ ~~
ganiC ~ul~ur-containing compound~ in combl~atlon ~itb metal car- :
boxylate~. A~ de~cribed in my U.S. pat~nt No. 3,qB7,5~B, the utility and efficiency of ~uch antlmony co~pound~ ar~ improved in the heat stabilization of vinyl halldc re6in~ to a~ unexpected degree. It has been observed, however, that ~uch antimony com-pound~ which are normally liquld tend to deteriorate or become unstable upon 6torage.
Summary of the Invention , '~
' :~ a. s . Patent 4,029,618 issued June 14, 1977 is directed to further improvements in vinyl halide resin sta-bilizer syfit~ms of antimony organic 6ul~ur-containing compounds.
The invention described therein in one of it6 aspects provided for synergi6tic heat 6tabilizer composition~ of antimony compounds afi stabilizers and ortho-dihydric phenols. In anothe~ of it~
-2-.~ . , ' :1 r ~
38173 r~
j,~
significant fea~urcs, antim~,ny organic sulfur-containing compound~
are provided which are liquid and shelf-stable at ambient tem-peratures. Such stable liquid compositions are ea~ily for~ulated into vinyl halide resin system6 and offer synergistically heat stabilized resin systems with enhanced resi~tance to both early discoloration and long term heat degradation of molded plastic~.
It was found that antimony organic sulfur-containlng compound~
were rendered shelf-stable with certain dihydric phenol~.
This application further amplifies liquid antimony compositions which are rendered ~tabl~ for storage ~ us~ ~t ambient conditions by the addition thereto o~ a phenolic co~pound.
For example, liquid antimony organic ~ulu~-containing compounds, including antimony mercaptoacid e~ter~, tend t~ det~rio~ate upon ~tanding. Such deterioration is ob~erved by ths ~o~matio~ and/or precipitation of ~olids in the liquid compound~. Th~ precl~e reason for this deterioration phenomenon i~ unknown. Neverthe-les8, the re~ulting heterogeneous li~uid~ not only in~rease the problems of measuring and mixing the antimony compounds lnto vinyl halide resins for stabilization, but practlcally 6peaking, heterogeneity causes a dissolute appesrance ~hich reduce~ the marketability of the antimony stabilizers. ~hu~, according to this` invention, liquid antimony compounds are rendered shelf-stable at ambient temperatures by the incorporation of a phenolic component such as an ortho-dihydric phenol.
There are certain generally preferred weight ratios of the antimony organic sulfur-containing compounds relative to a particular phenol in order to achieve ~tability. ~his will become apparent in view of the detailed operating examples.
~owever, it is to be emphasized that the most desirable weiqht ratios of each of the essential components o~ the compo~ition of 8~73 ~ l .. ~ ' this invention for a particnlar application can be arrived at, in accordance with the teachings of this invention, Thu~ ln its broader aspects, this invention iB not limited to wei~ht ratios of components. It has also been found that ~Ve~ ~
particular phenol in a particular antimony o~ganlc sulfu~-con-taining compound to achieve optimum ~tabi~ities un~e~ ceFtain conditions will vary as exemplified herein. But~ -in general, the phenol is combined with the antimony organic sulfur-containing compound in a~ amount ~ abou~ 0,~ to about 20percent by wei~ht o~ the antimony compound , and preferably between about 1 and 10 percent by weight as indicated ln U.S. Patent 4,029,618.
ANTIMONY ORGANIC SULFUR-CONTAINING COMPOUND
~ h~ antimony or~anic ~ul~u~ nta~nlP~ PompQund~ which a~q 6helf-~tabilized acco~din~ tQ thi~ lnvent~oP ~e gene~lly cha~aoterized as having the Sb - S group Q~ linkag~. ~uch anti-mony compound~ may be l~uid~ a~ no~al ~r ro~ tempq~atU~e6 4nd ~tmo~pheri~ condltion~. On the other h~nd~ ~uCh anti~ony com-poundg may be solids at normal temperatur~ ~nd ~py ~ten or melt at elevated temperature~, ~herefore, ll~Uid ~t~bllity at ambient conditions can be achieved ~her~ thq anti~ony compound is either in the normal liquid, hot melt, or ~olyent-containing state at room or ambient tempe~atures and pre~sureB where such compounds tend to undergo degradation due to the ambie~t condi-tions. In a mo6t preferred form, the 6tablliz~tion is achieved in liquid composltions,which are shelf-stable at ~oom o~ ambient temperatures. Such liquid compositions can be readily measured and mixed with other compositions, and are thu~ easy to ~ormulate, market and use.
Generally, most antimony organic compound~ ~ui~able for use in thi~ invention are derived from trivalent ~ntimony and _4_ : ~
0 S ~7 3 .
include merca~tid~s which m.ly be characterized by the ollowing formula:
Formula I. Sb(SR)3 wherein R represents hydrocarbon or sub~tituted hydrocarbon radicals such as those selected from the ~roup conslstin7 of alkyl, aryl or ara1kyl. Example6 of guch ~roupg are alkyl~ ~uch as ethyl, propyl, butyl, octyl, nonyl, lauryl and octadecyl;
aryls and aralkyls such as phenyl, bPnzyl, naphthy~, xylyl o~
phenyl ethyl and the like. The group SR of Formula I~ ~V~ in-stance, may be the rest of a ~ercaptan or ~erc~pto ~lcoho~. A~
indicated, aliphatlc and aromatic me~captan~ ~ay ~e ~mployed to form the group SR. In the ca~e of aliphatic me~apt~n~, those having 8 to 18 carbon atom~, e,g., decyl ~r dedecyl merc~ptan are u~ually pre~erred because the lower mercapta~ a~e un~it~bl~ for the pre~aration and use of the ~tabili~er~ c~ount ~ their offensive ~mell. 8uitable aromatlc mercaptanQ axe, ~u~ tance, thionaphthol, thiobenzyl alcohol, phenoxyethyl mer¢apta~, and others. As examples of ~uitable mercapto alcohol~, ~o~othio-ethylene glycol, monothiopropylene glycol, thioglycerol, thio-diethylene glycol, and other~ may be mentioned, ~pec~fic examples of such antimony mercaptides are antimony trilaurylmercaptide, antimony triphenylmercaptide snd antimony tribenzylmercaptide.
Patents exemplifying this formula Sb(SR)3 or a si~ilar formula and a definition of compounds represented thereby lnclude U.S.
Patent Nos. 2,684,956 and 3,466,261, among othe~.
Antimolly organic ~ulfur-containing compounds other than the antimony mercaptides of the Formula I above, are ~uitable for use according to this invention. Such compounds ~ g~nerally termed antimony m~rcaptoacid ester~ which may be further defined I~LO8173 by t~ followlll<3 formula:
Formula II. Sb(SRCOO~'~3 wherein R is selected from the gxoup consisting of alkylene, arylene, and aralkylene radicals and R' is a sub~tituted or un-substituted alkyl, aryl or mixed aryl-alkyl gXoup. ThUs R may be derived from mercapto acetic, ~ -mercaptopropionic, thiomalic, : thiosalicyclic acids, etc. Similarly, R' may be derived ~ro~
decanols, glycerol, glycol, monoesters, dihydr~abietyl ~lcohol, phenoxyethanol, pentaerythritol, etc. Particularly ~uitabl~ are the esters of mercapto alcohols, 8uCh a~ thioglycol~, in whic~ the hydroxy groups are esterified by an alipbat~c ! ~o~atic or ali-cyclic saturated or un8aturatod mon~çarboxyli~ ~Cid. ~a~ily available mercap~oacid ester~ a~e th~ ~ster~ o~ thiogly~olio acid, such as ethyl thioglycol~te, l~ooctylthiogly~ t'~, and generally the e6ters of mono and diba8ic aliphatic and aroma~lc m~roapo acid~, ~uch a~ esters of beta thlopropionic a~id, tb~laatic acid, thiobutyric acid and mercapto lauric acid. ~pecifia example~ of antimony mercaptoacid ester~ include antimony tri4 ~i~ooctyl-thloglycolate~, antimony tris ~glycoldime~captoacetate~l antimony tris ~dodecy.lthioglycolate), dodecylmercaptoantlmony bi~ ~iso-octylthioglycolate), and antimony tri~ (lsooctyl-~ ~me~captopro-pionate). Patent~ exemplifying Formula II o~ a'~imila~ formula and a definition of compounds represented thereby lnclude U.S.
PaLent No~. 2,680,726 and 3,530,15B, among other~.
The antimony organic sul~ur-containing compounds having the SbS group represented by Formulas I and II come within the scope of a broader characterization illustrated by the following formula;
¦ Pormula III. RnSbX3 n 11 , : ~ I
;38~73 wherein l~ is sclec~ed from lhe ~roup consisting of alkyl, alkenyl, ;
alkynyl, aryl, cycloalkyl, cycloalkenyl, and mixed aryl-alkyl, and substituted groups thereof, where X is eelected from the group consisting of sulfide (sulfur) or mercaptide and n i~ an integer of O to 2. of course, othe~ X group~ are SR and SRCOOR' d~fined by Formulas I and II above wherein R of the group SR is selected from alkyl, aryl, mixed aryl-alkyl, and 6ubstituted groups there-of, where R of the group SRCOOR~ i~ selected f~om ~lkylen~, ary-lene, aralkylene, and substituted group~ thereof, whe~e$n R' of the group SRCOOR' i8 6elected ~rom alkyl, aryl, mixed A~yl-alkyl, and 6ubstituted group~ thereof. Thi~ 1~ al~ ~ppare~ and with reference to the above 4r~~tl~Ye- i 3,530,15~ pate~t, that when X
i8 divalent, e.g. sulfide, t~e ~ompound may ~e RSbX ~ ~xemplified hereinafte~ by n-butyl antimony ~ulfide ~here ~ of ~n ~ Formula III i~ 1 and where n of X3~ 2. It i~ ~h~e~o~ ~ppreciated that the formulas hereip ar~ merely ~epr~6enta~iVe ~ndlci~ o~ the - clas~ of antimony compound6 which re~pond to th~ teaching~ of this invention. In the compound6~ RnSbX3_n which ~y ~e u~ed ln practice of this invention, R may be alkyl~ cyclo~lkyl~ alkenyl, cycloalkenyl, alkynyl, or aryl including ~uch group~ when inertly ubstituted. When ~ i8 alkyl, it may include methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, n-amyl, n-octyl, 2-ethyl-hexyl, etc. a6 well as sub6tituted alkyl~ lncluding phenylethyl, benzyl, etc. Typical alkenyl groups which may ~e employcd may include vinyl, 2-propenyl (i.e. allyl), l-propenyl, l-butenyl, 2-butenyl, etc. as wcll as inertly sub~tituted alkenyl groups typified by 4-phenyl, buten-l-yl, etc. ~ypical cycloalkyl group6 may lnclude cyclohexyl, cycloheptyl, cyclooctyl ag well a~ lnertly substituted cycloalkyl groups including 2-methyl cycloheptyl.
38173 r~
j,~
significant fea~urcs, antim~,ny organic sulfur-containing compound~
are provided which are liquid and shelf-stable at ambient tem-peratures. Such stable liquid compositions are ea~ily for~ulated into vinyl halide resin system6 and offer synergistically heat stabilized resin systems with enhanced resi~tance to both early discoloration and long term heat degradation of molded plastic~.
It was found that antimony organic sulfur-containlng compound~
were rendered shelf-stable with certain dihydric phenol~.
This application further amplifies liquid antimony compositions which are rendered ~tabl~ for storage ~ us~ ~t ambient conditions by the addition thereto o~ a phenolic co~pound.
For example, liquid antimony organic ~ulu~-containing compounds, including antimony mercaptoacid e~ter~, tend t~ det~rio~ate upon ~tanding. Such deterioration is ob~erved by ths ~o~matio~ and/or precipitation of ~olids in the liquid compound~. Th~ precl~e reason for this deterioration phenomenon i~ unknown. Neverthe-les8, the re~ulting heterogeneous li~uid~ not only in~rease the problems of measuring and mixing the antimony compounds lnto vinyl halide resins for stabilization, but practlcally 6peaking, heterogeneity causes a dissolute appesrance ~hich reduce~ the marketability of the antimony stabilizers. ~hu~, according to this` invention, liquid antimony compounds are rendered shelf-stable at ambient temperatures by the incorporation of a phenolic component such as an ortho-dihydric phenol.
There are certain generally preferred weight ratios of the antimony organic sulfur-containing compounds relative to a particular phenol in order to achieve ~tability. ~his will become apparent in view of the detailed operating examples.
~owever, it is to be emphasized that the most desirable weiqht ratios of each of the essential components o~ the compo~ition of 8~73 ~ l .. ~ ' this invention for a particnlar application can be arrived at, in accordance with the teachings of this invention, Thu~ ln its broader aspects, this invention iB not limited to wei~ht ratios of components. It has also been found that ~Ve~ ~
particular phenol in a particular antimony o~ganlc sulfu~-con-taining compound to achieve optimum ~tabi~ities un~e~ ceFtain conditions will vary as exemplified herein. But~ -in general, the phenol is combined with the antimony organic sulfur-containing compound in a~ amount ~ abou~ 0,~ to about 20percent by wei~ht o~ the antimony compound , and preferably between about 1 and 10 percent by weight as indicated ln U.S. Patent 4,029,618.
ANTIMONY ORGANIC SULFUR-CONTAINING COMPOUND
~ h~ antimony or~anic ~ul~u~ nta~nlP~ PompQund~ which a~q 6helf-~tabilized acco~din~ tQ thi~ lnvent~oP ~e gene~lly cha~aoterized as having the Sb - S group Q~ linkag~. ~uch anti-mony compound~ may be l~uid~ a~ no~al ~r ro~ tempq~atU~e6 4nd ~tmo~pheri~ condltion~. On the other h~nd~ ~uCh anti~ony com-poundg may be solids at normal temperatur~ ~nd ~py ~ten or melt at elevated temperature~, ~herefore, ll~Uid ~t~bllity at ambient conditions can be achieved ~her~ thq anti~ony compound is either in the normal liquid, hot melt, or ~olyent-containing state at room or ambient tempe~atures and pre~sureB where such compounds tend to undergo degradation due to the ambie~t condi-tions. In a mo6t preferred form, the 6tablliz~tion is achieved in liquid composltions,which are shelf-stable at ~oom o~ ambient temperatures. Such liquid compositions can be readily measured and mixed with other compositions, and are thu~ easy to ~ormulate, market and use.
Generally, most antimony organic compound~ ~ui~able for use in thi~ invention are derived from trivalent ~ntimony and _4_ : ~
0 S ~7 3 .
include merca~tid~s which m.ly be characterized by the ollowing formula:
Formula I. Sb(SR)3 wherein R represents hydrocarbon or sub~tituted hydrocarbon radicals such as those selected from the ~roup conslstin7 of alkyl, aryl or ara1kyl. Example6 of guch ~roupg are alkyl~ ~uch as ethyl, propyl, butyl, octyl, nonyl, lauryl and octadecyl;
aryls and aralkyls such as phenyl, bPnzyl, naphthy~, xylyl o~
phenyl ethyl and the like. The group SR of Formula I~ ~V~ in-stance, may be the rest of a ~ercaptan or ~erc~pto ~lcoho~. A~
indicated, aliphatlc and aromatic me~captan~ ~ay ~e ~mployed to form the group SR. In the ca~e of aliphatic me~apt~n~, those having 8 to 18 carbon atom~, e,g., decyl ~r dedecyl merc~ptan are u~ually pre~erred because the lower mercapta~ a~e un~it~bl~ for the pre~aration and use of the ~tabili~er~ c~ount ~ their offensive ~mell. 8uitable aromatlc mercaptanQ axe, ~u~ tance, thionaphthol, thiobenzyl alcohol, phenoxyethyl mer¢apta~, and others. As examples of ~uitable mercapto alcohol~, ~o~othio-ethylene glycol, monothiopropylene glycol, thioglycerol, thio-diethylene glycol, and other~ may be mentioned, ~pec~fic examples of such antimony mercaptides are antimony trilaurylmercaptide, antimony triphenylmercaptide snd antimony tribenzylmercaptide.
Patents exemplifying this formula Sb(SR)3 or a si~ilar formula and a definition of compounds represented thereby lnclude U.S.
Patent Nos. 2,684,956 and 3,466,261, among othe~.
Antimolly organic ~ulfur-containing compounds other than the antimony mercaptides of the Formula I above, are ~uitable for use according to this invention. Such compounds ~ g~nerally termed antimony m~rcaptoacid ester~ which may be further defined I~LO8173 by t~ followlll<3 formula:
Formula II. Sb(SRCOO~'~3 wherein R is selected from the gxoup consisting of alkylene, arylene, and aralkylene radicals and R' is a sub~tituted or un-substituted alkyl, aryl or mixed aryl-alkyl gXoup. ThUs R may be derived from mercapto acetic, ~ -mercaptopropionic, thiomalic, : thiosalicyclic acids, etc. Similarly, R' may be derived ~ro~
decanols, glycerol, glycol, monoesters, dihydr~abietyl ~lcohol, phenoxyethanol, pentaerythritol, etc. Particularly ~uitabl~ are the esters of mercapto alcohols, 8uCh a~ thioglycol~, in whic~ the hydroxy groups are esterified by an alipbat~c ! ~o~atic or ali-cyclic saturated or un8aturatod mon~çarboxyli~ ~Cid. ~a~ily available mercap~oacid ester~ a~e th~ ~ster~ o~ thiogly~olio acid, such as ethyl thioglycol~te, l~ooctylthiogly~ t'~, and generally the e6ters of mono and diba8ic aliphatic and aroma~lc m~roapo acid~, ~uch a~ esters of beta thlopropionic a~id, tb~laatic acid, thiobutyric acid and mercapto lauric acid. ~pecifia example~ of antimony mercaptoacid ester~ include antimony tri4 ~i~ooctyl-thloglycolate~, antimony tris ~glycoldime~captoacetate~l antimony tris ~dodecy.lthioglycolate), dodecylmercaptoantlmony bi~ ~iso-octylthioglycolate), and antimony tri~ (lsooctyl-~ ~me~captopro-pionate). Patent~ exemplifying Formula II o~ a'~imila~ formula and a definition of compounds represented thereby lnclude U.S.
PaLent No~. 2,680,726 and 3,530,15B, among other~.
The antimony organic sul~ur-containing compounds having the SbS group represented by Formulas I and II come within the scope of a broader characterization illustrated by the following formula;
¦ Pormula III. RnSbX3 n 11 , : ~ I
;38~73 wherein l~ is sclec~ed from lhe ~roup consisting of alkyl, alkenyl, ;
alkynyl, aryl, cycloalkyl, cycloalkenyl, and mixed aryl-alkyl, and substituted groups thereof, where X is eelected from the group consisting of sulfide (sulfur) or mercaptide and n i~ an integer of O to 2. of course, othe~ X group~ are SR and SRCOOR' d~fined by Formulas I and II above wherein R of the group SR is selected from alkyl, aryl, mixed aryl-alkyl, and 6ubstituted groups there-of, where R of the group SRCOOR~ i~ selected f~om ~lkylen~, ary-lene, aralkylene, and substituted group~ thereof, whe~e$n R' of the group SRCOOR' i8 6elected ~rom alkyl, aryl, mixed A~yl-alkyl, and 6ubstituted group~ thereof. Thi~ 1~ al~ ~ppare~ and with reference to the above 4r~~tl~Ye- i 3,530,15~ pate~t, that when X
i8 divalent, e.g. sulfide, t~e ~ompound may ~e RSbX ~ ~xemplified hereinafte~ by n-butyl antimony ~ulfide ~here ~ of ~n ~ Formula III i~ 1 and where n of X3~ 2. It i~ ~h~e~o~ ~ppreciated that the formulas hereip ar~ merely ~epr~6enta~iVe ~ndlci~ o~ the - clas~ of antimony compound6 which re~pond to th~ teaching~ of this invention. In the compound6~ RnSbX3_n which ~y ~e u~ed ln practice of this invention, R may be alkyl~ cyclo~lkyl~ alkenyl, cycloalkenyl, alkynyl, or aryl including ~uch group~ when inertly ubstituted. When ~ i8 alkyl, it may include methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, n-amyl, n-octyl, 2-ethyl-hexyl, etc. a6 well as sub6tituted alkyl~ lncluding phenylethyl, benzyl, etc. Typical alkenyl groups which may ~e employcd may include vinyl, 2-propenyl (i.e. allyl), l-propenyl, l-butenyl, 2-butenyl, etc. as wcll as inertly sub~tituted alkenyl groups typified by 4-phenyl, buten-l-yl, etc. ~ypical cycloalkyl group6 may lnclude cyclohexyl, cycloheptyl, cyclooctyl ag well a~ lnertly substituted cycloalkyl groups including 2-methyl cycloheptyl.
3-butyl cyclohexyl, 3-methylcyclohexyl, etc. ~ypical alkynyl .:
8~3 .~
groups whi~ m~y L~e ~mploye~l include propyn-l-yl, propyn-2-yl, butyn-l-yl, phenlethynyl, ethynyl, etc. Typical aryl gr~ups which may be employed may include phenyl, tolyl, xylyl, chlaro-phenyl, dimethylaminophenyl, etc. Where mo~e than one R o~ X i~
present in Formula III, such groups may be the ~ame ~r dlf~erent.
Typical mercaptide~ include phenyl mercaptide, l~uryl mercaptide, butyl mercaptide~ or dimercaptides includin~ aliphatic, cyclo-aliphatic, or aromatic dimercaptan6 of the ~ groups di~closed herein, etc. Specific compound~ when n is 1 or 2 lnc~ude n-butyl antimony dilaurylmercaptide, n-butyl anti~ony ~ul~ide, di-n-butyl antimony lauryl mercaptide, diph~nyl anti~ony ?au~yl m~qaptide, ditolyl antimony n amyl mercaptlde~ dibenzyl a~timo~y ~nzyl mer-captide, diallyl antimony cyclohexyl me~çapt~d~, diphenyl anti~ony allkylme~captide, dlcyclohexyl antimo~y ~-~exyl merca~tide, di-tolyl antimony phenyl me~captlde~ dl-l~opropyl ~ntimo~y 2-ethyl-hexyl mercaptlde, di-p-chlo~ophenyl antlmony n-~utyl ~rcaptide, diphenyl antimony ethyl me~captoacetat~. Patent~ exem~ ying such antimony compound~ lnclude U.S. Patent ~. 3,53~15~ and 3,399~220. ~here the R ~roup i~ ary~oxy, alkyloxy, a~k~ryloxy, acyloxy, etc., ~peciflc example~ from which th~ group i~
derlved may include 2-ethylhexanol, phenol, nonylphenol~ xylenol, 2-ethylhexoic acid, oleic acid, lauric acid, benzoic acid and the like, Of cour6e, it i~ apparent that antimony merc~ptldes, antimony mercapto acids, antimony mercaptoacid est~r~, et~., per 6e form no part of this invention and the mentloned patent~ and their specific di6closure~ clearly teach these compounds and their method of production to enable anyone of ordinary skill to use e m in carrying out thi~ lnvention.
~ ?
.
:.
.
81~3 PHENOLS
The terms "phenol" and "phenols" as used herein are in-ten~ed to include mono- or polynuclear phenols exemplified by the benzene or naphthalene nucleus, and,the su~stituted forms of such a nucleus. As reported in my earlier mentioned copending appli-cation, the ortho-dihydric phenols of such mono or polynuclear phenols have already been found by me to provide liquid, shelf-stable compositions of antimony compounds at ambient temperatures.
Specific examples of such ortho-dihydric phencls include catechol tertiary butyl catechol, and 2,3 dihydroxynaphthalene. I no~
find that the stability of such antimony compounds Can also be maint~ined b~ ther phenols r ~- ented by the following formula:
wherein Rl, R2, R3, R4 or R5 can be hydrogen, alkyl, aryl, hydroxyl, alkoxy, aryloxy, alkaryl, aralkyl, other substituted groups of said aryl or alkyl, and the like, provided all are not hydrogen, or they may form a part of an aromatic or alkylated aromatic nucleus as in the case when the phenolic nucleus is naphthalene, Alkyl substituted groups of mono or polynuclear phenols of this formula include straight or branched chain groups of C1_12, such as methyl, ethyl, propyl, pentyl, hçxyl, heptyl, dodecyl, or tertiary butyl, isopropyl, e~c., forms. The presently preferred phenols of this invention are the catechol derivatives because of their performance and commercial availability. Other dihydric or trihydric phenols, or other functionally substituted ~1~38~73 mono-, di- or polyhydric ph~llols can be employed. Included in such phellols are mono-, di-, tri- isobutyl or i80ctyl phenolt 2,4,5-trihydroxybutyroPhen0rle; butylated hydroxyanisol~ whlch is a mixture of ortho- and meta-butyl parahydrq~yani~le~ 5ecquinols resorcinol; 2,6-di-t-butyl-~-cresol; reso~cinol mon~benzoate and ~-octylphenyl salicylate. It will be appreciated ~at speci~ic phencls may be used to achieve stabilization result8 along with other advantages as empirically demon~trated in numerQu~ ~pe~ating examples of this invention, and a further understandi~g thereof `~
w111 become apparent in v~eW of the detailed de~crip~i~n he~ein.
Thus, in accordance with the present teachings, a liquid antimony-based composition is provided which is stable under ambient conditions and consists essentially of:
a liquid comprising an antimony organic sulfur-containing compound having the formula:
n 3 where R is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkenyl, mixed aryl-alkyl, .and substituted groups thereof, where X is selected from the group consisting of sulfur, SR and SRCOOR' wherein R of the group SR is selected from alkyl, aryl, mixed aryl-alkyl~ and substituted groups thereof, where R of the group SRCOOR' is selected from alkylene, arylene, aralkylene, and substituted groups thereof, wherein R' of the group SRCOOR' is selected from alkyl, aryl, mixed aryl-alkyl, and substituted groups thereof, where n is an integer of 0 to 2, and a minor amount by weight of the compound of a phenol chosen from one of the following:
(i) monohydric phenols having alkyl, aryl, alkoxy, aryloxy, alkaryl, aralkyl or other substituted alkyl or aryl constituents on the nucleus thereof (ii) meta- and para-dihydric phenols and substituted ~, -10-.~, .
- . ~ . .
meta- and para-dihydric phenols (iii) trihydric phenols and substituted trihydric phenols.
The principles o~ this lnven~14~ ~nd 1~9 op~dtlp~
parameter6 will be further unde~too~ Wlth r~ ence ~0 following detailed example~ which s~rv~ to illu~t~ate ~h~ type~
o~ ~pecific ~aterial~ and thei~ ~m~unt~ a~ ~s~d in ~h~ fitabil~
zation o~ antimony compounda ~ccording to thi~ inyention. ~heae examples are considered~to be exemplary o~ th~ inventlon, and should not ~e considered a~ limiting, e6pecially ln vi~w o~
applicant' 5 broad di~closure o~ prin~iple~ o~ ~hifi inVe~t$on.
In the examples of Table~ I and TI ~hich follow, various combination's of an antimony organi~ 6ul~ur-containing compound and a phenol were blended together to ~orm ~ liquid composition on a parts by weight basi~. All amou~t~ o~ com-ponents are on a percent by weight ba6is, or a~ ~ndicated, simply "~". The phenols were lncorporated in ~ llquid antimony tris-isooctylt~ioglycolate (ATG) on the ~basi~ o~ a~out 0.1 to about 20 percent by wei~ht of the antimony compound a~ indicated in the Tables. The stabillties of the resulting blend~ of ATG
and t-butyl catechol (T~C) or ATG and butylated hydro~yanisole (~HA) were de~ermined at normal room temperature and p~es6ure ~20-25C an~ atmospheric), as reported in Tables I and II, respectively, in open bottle~.
,: .
B -lOa -r TABLE I
% TBC TIME
1 dày 1 wk. 1 2 wks. 3 wks. 4 Wks.
. . . .. __.
0 Clear Clear Hazy Hazy ~azy _ . ........ ._.. ... _.. __ . .
0.1 Clear Clear Clear Clear Clear ~ . .. .. __ . __ . , ~, _ _ _ ._ r 0.5 Clear Clear Clear Clear Clear 1.0 Clear Clear Clear Clear Clear : L0.0 Clear Clear Clear Clear Cleax .. . ~. . . . ..... _ : 20.0 Clear Clear Clear Clear Clear - -, S~73 _, UJ _ _ . _, _ . . .
Ul '1 ~ ~ h,i ~1 ,~~1 t)' nl rd t~U~ ::~ Ul ~. Ul ~ Ul ':c la O al ~ N N N N
n. ~ ~ ~ 0 ~ ~1 ~ 0 ~ ,d O ~ U l) ~ ~ ~ ~ ~ ~ ,d __ ___ _. . _~
. a~ .
U~ :~ ~, . ~.~ ~n 3 a N N ~1 ~1 ~ C) ~ N
1~ g' ~.C ~.C O U ~1 U 11~1 __ , . ____ - _ __ .
. ~ .
u) ~ ,1 ~ 1~ h ~ h ~' ~ U~ ~ ~ ~ ~ ~
3 (a . N N ~\ O O ~\
~, ~ rd . ~ ~1 ~1 ~ ~ _1 ~O O Ul ~ ~ ~ U U U U U
:~ _I ~ ~ h tl' ~1 U~ ~ 1~ Id Id 1 3 lll ~ N N U a~ 0,~
a. 1-l ~ ' Id r-~ ~1 _1 rl ,_ U~ O Ul ~: ~ U O U ~ t.) . .. . __ . .
n ,~ h ~ ~ ~ .
;~ N ~ U) ~ 1~1~d ~d ~ ~ ~ _~
U~,C ~ 1~ U O 1~ 1,~
H _ _ __ _ _ . .
E~
,X ~ ~ ; I
3 N N N ~\
. ~ ~1 ~ _~ ~ _~
P~ U U U V ~ ' ' i~ _ _ __ .. .- _ __ , ','' U~ ~ ~ ~ ~ ~
~a 3 N N ~J ~ a) a~ ~ a~
~1 ,~ a ,~ ,~ ,~ _, r-~ ~
~ ~.' ~ U U U U ~ U
_ __ _ __ __ .. , . H ~ h 1~ h ~1 h .Y:~1 u~ :~ ~d ~d nl rd nl ,a ~ N N ~1 O O q~ a) ~1 ,a nl -~ ~1 ~1 ~ ~ r~
~1 ~ P~ U U U U U U
_ _ . - _ , ~ ~ ~ h h h h h ~ ~ In ~ ~ ~ ~ ~ ~
N N q~ al ~ ~ ~1 ~U
n~ ,~ ~ ~ ~1 ~_1 ~1 . r~Ul.C ~ .L U ~ V U U U
.
~ h 1~ ~ 1~ h ~ ~ h l~ ~ Id Id n~ Id~d l~ Id a~
~1 ~ ~ ~ . ~ ~ ~1 ., ,~ U U U U U U U U
_ __ m o o c, o 1~ r) r~
~P _ . o _ _ ._ t 1i 8173~ ~
In tl~e ~rables "wk." or "wks." means week(s); "clear"
means homogeneous transparellt liquid; "v. sl. hazy" means Yery minor amount of insolvent partiele appcarance; "s1. hazy" and "hazy" respectively means increasing insolvent appearance; and "opaque" means loss of transparency. Thu~, as can be seen by both Tables, at room temperature and normal atmospher~, the unmodified liquid antimony compound develops haze and becomes opaque on standing for several weeks. In the presence of minor amounts of t-butyl catechol, no deterioration is noted (see Table I). The stabilizing response of TBC would appear to be linear with increasing amounts. However, Table II demonstrates that the stabilizing response of butylated hydroxy anisole (BHA) is not completely linear. Rather, while improvements are observed with varying amounts of O.l to 5.0~, complete clarity is retained throughout an eight week period with about 0.3 to 2% of BHA.
Accelerated shelf stability tests have also been con-ducted. In these tests an apparatus was a~embled to supply air to liquid antimony samples containing varying amounts of phenols.
An alr supply was connected to a ~lowmeter and through a hose to a 1000 ml vacuum flask containing 750 mls water. After bubbl~ng through the water, the air was conducted through a glass tube to a 400 ml beaker containing 150 ~rams of antimony tris- lsooctyl-thioglycolate heated to 260F, for bu~bling throu~h the liquid.
Procedurally, the antimony liquid was charged lnto the beaker and desired percents of phenols were added to liquid samples. Then, the liquid was stirred under a temperature held at 260F with
8~3 .~
groups whi~ m~y L~e ~mploye~l include propyn-l-yl, propyn-2-yl, butyn-l-yl, phenlethynyl, ethynyl, etc. Typical aryl gr~ups which may be employed may include phenyl, tolyl, xylyl, chlaro-phenyl, dimethylaminophenyl, etc. Where mo~e than one R o~ X i~
present in Formula III, such groups may be the ~ame ~r dlf~erent.
Typical mercaptide~ include phenyl mercaptide, l~uryl mercaptide, butyl mercaptide~ or dimercaptides includin~ aliphatic, cyclo-aliphatic, or aromatic dimercaptan6 of the ~ groups di~closed herein, etc. Specific compound~ when n is 1 or 2 lnc~ude n-butyl antimony dilaurylmercaptide, n-butyl anti~ony ~ul~ide, di-n-butyl antimony lauryl mercaptide, diph~nyl anti~ony ?au~yl m~qaptide, ditolyl antimony n amyl mercaptlde~ dibenzyl a~timo~y ~nzyl mer-captide, diallyl antimony cyclohexyl me~çapt~d~, diphenyl anti~ony allkylme~captide, dlcyclohexyl antimo~y ~-~exyl merca~tide, di-tolyl antimony phenyl me~captlde~ dl-l~opropyl ~ntimo~y 2-ethyl-hexyl mercaptlde, di-p-chlo~ophenyl antlmony n-~utyl ~rcaptide, diphenyl antimony ethyl me~captoacetat~. Patent~ exem~ ying such antimony compound~ lnclude U.S. Patent ~. 3,53~15~ and 3,399~220. ~here the R ~roup i~ ary~oxy, alkyloxy, a~k~ryloxy, acyloxy, etc., ~peciflc example~ from which th~ group i~
derlved may include 2-ethylhexanol, phenol, nonylphenol~ xylenol, 2-ethylhexoic acid, oleic acid, lauric acid, benzoic acid and the like, Of cour6e, it i~ apparent that antimony merc~ptldes, antimony mercapto acids, antimony mercaptoacid est~r~, et~., per 6e form no part of this invention and the mentloned patent~ and their specific di6closure~ clearly teach these compounds and their method of production to enable anyone of ordinary skill to use e m in carrying out thi~ lnvention.
~ ?
.
:.
.
81~3 PHENOLS
The terms "phenol" and "phenols" as used herein are in-ten~ed to include mono- or polynuclear phenols exemplified by the benzene or naphthalene nucleus, and,the su~stituted forms of such a nucleus. As reported in my earlier mentioned copending appli-cation, the ortho-dihydric phenols of such mono or polynuclear phenols have already been found by me to provide liquid, shelf-stable compositions of antimony compounds at ambient temperatures.
Specific examples of such ortho-dihydric phencls include catechol tertiary butyl catechol, and 2,3 dihydroxynaphthalene. I no~
find that the stability of such antimony compounds Can also be maint~ined b~ ther phenols r ~- ented by the following formula:
wherein Rl, R2, R3, R4 or R5 can be hydrogen, alkyl, aryl, hydroxyl, alkoxy, aryloxy, alkaryl, aralkyl, other substituted groups of said aryl or alkyl, and the like, provided all are not hydrogen, or they may form a part of an aromatic or alkylated aromatic nucleus as in the case when the phenolic nucleus is naphthalene, Alkyl substituted groups of mono or polynuclear phenols of this formula include straight or branched chain groups of C1_12, such as methyl, ethyl, propyl, pentyl, hçxyl, heptyl, dodecyl, or tertiary butyl, isopropyl, e~c., forms. The presently preferred phenols of this invention are the catechol derivatives because of their performance and commercial availability. Other dihydric or trihydric phenols, or other functionally substituted ~1~38~73 mono-, di- or polyhydric ph~llols can be employed. Included in such phellols are mono-, di-, tri- isobutyl or i80ctyl phenolt 2,4,5-trihydroxybutyroPhen0rle; butylated hydroxyanisol~ whlch is a mixture of ortho- and meta-butyl parahydrq~yani~le~ 5ecquinols resorcinol; 2,6-di-t-butyl-~-cresol; reso~cinol mon~benzoate and ~-octylphenyl salicylate. It will be appreciated ~at speci~ic phencls may be used to achieve stabilization result8 along with other advantages as empirically demon~trated in numerQu~ ~pe~ating examples of this invention, and a further understandi~g thereof `~
w111 become apparent in v~eW of the detailed de~crip~i~n he~ein.
Thus, in accordance with the present teachings, a liquid antimony-based composition is provided which is stable under ambient conditions and consists essentially of:
a liquid comprising an antimony organic sulfur-containing compound having the formula:
n 3 where R is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkenyl, mixed aryl-alkyl, .and substituted groups thereof, where X is selected from the group consisting of sulfur, SR and SRCOOR' wherein R of the group SR is selected from alkyl, aryl, mixed aryl-alkyl~ and substituted groups thereof, where R of the group SRCOOR' is selected from alkylene, arylene, aralkylene, and substituted groups thereof, wherein R' of the group SRCOOR' is selected from alkyl, aryl, mixed aryl-alkyl, and substituted groups thereof, where n is an integer of 0 to 2, and a minor amount by weight of the compound of a phenol chosen from one of the following:
(i) monohydric phenols having alkyl, aryl, alkoxy, aryloxy, alkaryl, aralkyl or other substituted alkyl or aryl constituents on the nucleus thereof (ii) meta- and para-dihydric phenols and substituted ~, -10-.~, .
- . ~ . .
meta- and para-dihydric phenols (iii) trihydric phenols and substituted trihydric phenols.
The principles o~ this lnven~14~ ~nd 1~9 op~dtlp~
parameter6 will be further unde~too~ Wlth r~ ence ~0 following detailed example~ which s~rv~ to illu~t~ate ~h~ type~
o~ ~pecific ~aterial~ and thei~ ~m~unt~ a~ ~s~d in ~h~ fitabil~
zation o~ antimony compounda ~ccording to thi~ inyention. ~heae examples are considered~to be exemplary o~ th~ inventlon, and should not ~e considered a~ limiting, e6pecially ln vi~w o~
applicant' 5 broad di~closure o~ prin~iple~ o~ ~hifi inVe~t$on.
In the examples of Table~ I and TI ~hich follow, various combination's of an antimony organi~ 6ul~ur-containing compound and a phenol were blended together to ~orm ~ liquid composition on a parts by weight basi~. All amou~t~ o~ com-ponents are on a percent by weight ba6is, or a~ ~ndicated, simply "~". The phenols were lncorporated in ~ llquid antimony tris-isooctylt~ioglycolate (ATG) on the ~basi~ o~ a~out 0.1 to about 20 percent by wei~ht of the antimony compound a~ indicated in the Tables. The stabillties of the resulting blend~ of ATG
and t-butyl catechol (T~C) or ATG and butylated hydro~yanisole (~HA) were de~ermined at normal room temperature and p~es6ure ~20-25C an~ atmospheric), as reported in Tables I and II, respectively, in open bottle~.
,: .
B -lOa -r TABLE I
% TBC TIME
1 dày 1 wk. 1 2 wks. 3 wks. 4 Wks.
. . . .. __.
0 Clear Clear Hazy Hazy ~azy _ . ........ ._.. ... _.. __ . .
0.1 Clear Clear Clear Clear Clear ~ . .. .. __ . __ . , ~, _ _ _ ._ r 0.5 Clear Clear Clear Clear Clear 1.0 Clear Clear Clear Clear Clear : L0.0 Clear Clear Clear Clear Cleax .. . ~. . . . ..... _ : 20.0 Clear Clear Clear Clear Clear - -, S~73 _, UJ _ _ . _, _ . . .
Ul '1 ~ ~ h,i ~1 ,~~1 t)' nl rd t~U~ ::~ Ul ~. Ul ~ Ul ':c la O al ~ N N N N
n. ~ ~ ~ 0 ~ ~1 ~ 0 ~ ,d O ~ U l) ~ ~ ~ ~ ~ ~ ,d __ ___ _. . _~
. a~ .
U~ :~ ~, . ~.~ ~n 3 a N N ~1 ~1 ~ C) ~ N
1~ g' ~.C ~.C O U ~1 U 11~1 __ , . ____ - _ __ .
. ~ .
u) ~ ,1 ~ 1~ h ~ h ~' ~ U~ ~ ~ ~ ~ ~
3 (a . N N ~\ O O ~\
~, ~ rd . ~ ~1 ~1 ~ ~ _1 ~O O Ul ~ ~ ~ U U U U U
:~ _I ~ ~ h tl' ~1 U~ ~ 1~ Id Id 1 3 lll ~ N N U a~ 0,~
a. 1-l ~ ' Id r-~ ~1 _1 rl ,_ U~ O Ul ~: ~ U O U ~ t.) . .. . __ . .
n ,~ h ~ ~ ~ .
;~ N ~ U) ~ 1~1~d ~d ~ ~ ~ _~
U~,C ~ 1~ U O 1~ 1,~
H _ _ __ _ _ . .
E~
,X ~ ~ ; I
3 N N N ~\
. ~ ~1 ~ _~ ~ _~
P~ U U U V ~ ' ' i~ _ _ __ .. .- _ __ , ','' U~ ~ ~ ~ ~ ~
~a 3 N N ~J ~ a) a~ ~ a~
~1 ,~ a ,~ ,~ ,~ _, r-~ ~
~ ~.' ~ U U U U ~ U
_ __ _ __ __ .. , . H ~ h 1~ h ~1 h .Y:~1 u~ :~ ~d ~d nl rd nl ,a ~ N N ~1 O O q~ a) ~1 ,a nl -~ ~1 ~1 ~ ~ r~
~1 ~ P~ U U U U U U
_ _ . - _ , ~ ~ ~ h h h h h ~ ~ In ~ ~ ~ ~ ~ ~
N N q~ al ~ ~ ~1 ~U
n~ ,~ ~ ~ ~1 ~_1 ~1 . r~Ul.C ~ .L U ~ V U U U
.
~ h 1~ ~ 1~ h ~ ~ h l~ ~ Id Id n~ Id~d l~ Id a~
~1 ~ ~ ~ . ~ ~ ~1 ., ,~ U U U U U U U U
_ __ m o o c, o 1~ r) r~
~P _ . o _ _ ._ t 1i 8173~ ~
In tl~e ~rables "wk." or "wks." means week(s); "clear"
means homogeneous transparellt liquid; "v. sl. hazy" means Yery minor amount of insolvent partiele appcarance; "s1. hazy" and "hazy" respectively means increasing insolvent appearance; and "opaque" means loss of transparency. Thu~, as can be seen by both Tables, at room temperature and normal atmospher~, the unmodified liquid antimony compound develops haze and becomes opaque on standing for several weeks. In the presence of minor amounts of t-butyl catechol, no deterioration is noted (see Table I). The stabilizing response of TBC would appear to be linear with increasing amounts. However, Table II demonstrates that the stabilizing response of butylated hydroxy anisole (BHA) is not completely linear. Rather, while improvements are observed with varying amounts of O.l to 5.0~, complete clarity is retained throughout an eight week period with about 0.3 to 2% of BHA.
Accelerated shelf stability tests have also been con-ducted. In these tests an apparatus was a~embled to supply air to liquid antimony samples containing varying amounts of phenols.
An alr supply was connected to a ~lowmeter and through a hose to a 1000 ml vacuum flask containing 750 mls water. After bubbl~ng through the water, the air was conducted through a glass tube to a 400 ml beaker containing 150 ~rams of antimony tris- lsooctyl-thioglycolate heated to 260F, for bu~bling throu~h the liquid.
Procedurally, the antimony liquid was charged lnto the beaker and desired percents of phenols were added to liquid samples. Then, the liquid was stirred under a temperature held at 260F with
4 SCF~I of air supplied. With the passage of time in minutes, the moment of opacity was recorded a~ the time at which the centrally located glas~ tube in the beaker evolving ~ir could not be ~een when viewed through the side of the beaker.
Employing the accelerated tests described above, opacity occurred for varying percents of TBC as shown in Table III. The control (0%) opacified in 22 minutes.
:
TABLE I I I
":
96 . Opacity TBC ~min . ) -`. o 22 ~:. 0,5 44 :
"~
~- 1 . 25 61 ., j ~
2.0 6 2 . 5 Bl : 3~ 5 112 ` 5. 0 138 ~' ~
,,~
, ........................................................................ .
. . ~
.: ~ - ' ' '~ , Thus, TBC achieves a linear stabilization of the liquid antimony over a period of time with increasing amounts.
This accelerated data of Table III confirms ambient test results on TBC in the sense that increased stability is achieved with increasing amountC of phenol.
Accelerated tests were also performed for BHA under the same conditions described above and the results are reported in Table IV.
1 IJ8~3 % ûpacity ~A (min. ) O
0.5 31 1. 25 2B
~.0 ~8 ., .
2.5 ~3 3.0 36 3.5 23 g . 25 2S
Employing the accelerated tests described above, opacity occurred for varying percents of TBC as shown in Table III. The control (0%) opacified in 22 minutes.
:
TABLE I I I
":
96 . Opacity TBC ~min . ) -`. o 22 ~:. 0,5 44 :
"~
~- 1 . 25 61 ., j ~
2.0 6 2 . 5 Bl : 3~ 5 112 ` 5. 0 138 ~' ~
,,~
, ........................................................................ .
. . ~
.: ~ - ' ' '~ , Thus, TBC achieves a linear stabilization of the liquid antimony over a period of time with increasing amounts.
This accelerated data of Table III confirms ambient test results on TBC in the sense that increased stability is achieved with increasing amountC of phenol.
Accelerated tests were also performed for BHA under the same conditions described above and the results are reported in Table IV.
1 IJ8~3 % ûpacity ~A (min. ) O
0.5 31 1. 25 2B
~.0 ~8 ., .
2.5 ~3 3.0 36 3.5 23 g . 25 2S
5.0 26 :-Accelerated data of Table IV thus parallels the data of Table II above and indicates its reliability in similarly predicting long term shelf storage stability for the liquid antimony compositions.
Employing accelerated tests, at 2.5~ phenol component in ATG, improvements of at least about 20 minutes in stability have been observed for butylated hydroxy anisole; p-dihydroxy-benzene; _-dihydroxybenzene; 2,6-di tert-butyl-para-cresol;
resorcinol monobenzoate; p-octylphenyl salicylate; a mixture of di- and tri-alkyl phenols where the alkyl group substituted in the 2, 3 and 5 positions is isobutyl or isooctyl; o-dihydroxy-~` benzene; and 2, 4, 5-trihydroxybutyrophenone. In the case of phenols such as butylated hydroxy anisole; 2,2'-bis (4-hydroxy-phenyl) propane; 4,4'-butylidenebis (6-tert-butyl-_-cresol);
4,4'-thiobis-(6-tert-butyl-m-cresol); and 2-3 dihydroxynaphtha-lene, improvements are observed at levels between 0.5-5.0~, but ` optimums vary depending upon the phenol and the particular antimony compound.
In addition to the above examples, as reported in my earlier application examples, the combination of several o-; dihydric phenols and liquid antimony tris (isooctyl-~-mercapto-propionate), hereinafter "ATP", were demonstrated. Each of the combinations containing 5% phenol were shelf-stable liquids at ambient temperature. The _-dihydric phenols were 4-tertiary butyl catechol, catechol and 2,3-dihydroxynaphthalene.
As developed above, the antim~ny compound may be liquid in its normal state, i.e., at room temperature and atmo-spheric pressure. Also, the antimony compound may be rendered liquid by the addition of a solvent. In this connection, :
,~ -.
l08173 antimony tris ~lauryl mercaptide) is a pasty solid at ambient temperatures~ A composition of 50% hydrocarbon solvent and 50 antimony tris (lauryl mercaptide) was formulated and at room temperature and ambient pressure was a clear liquid. When a sample of such a composition wa6 tested fo~ ~tability under th~
accelerated p~ocedure described above, a control wlthout phenolic stabilizer became opaque after about 35 minutest Upon the addi-bv weight 4-tion of ~%/ tertiary butyl catechol, and the per~ormance ~f the accelerated tests under the same condition~ aq the control, the phenollc containing compo6ition did not be~m~ ~a~ue ~ntil A
passage of 70 mlnute~ Accordin~ly, liquid antim4ny ~abili~er composltions in a normal ~tate or solvat~ 8t~te ~n b~ ~tabilized in accordance with the prlnciple~ ~ this inv~n~lon.
It is als~ to be unde~tood t~a~ ~h~ ~omponent~ can be used and the benefits of this in~ention can bo achl~ved.
Accordingly, other ~odificatio~ will beco~ pa~on~ in Yiew of the teachings hereln wlthout departing from tha tXu~ spirit and Scope of this invention.
Employing accelerated tests, at 2.5~ phenol component in ATG, improvements of at least about 20 minutes in stability have been observed for butylated hydroxy anisole; p-dihydroxy-benzene; _-dihydroxybenzene; 2,6-di tert-butyl-para-cresol;
resorcinol monobenzoate; p-octylphenyl salicylate; a mixture of di- and tri-alkyl phenols where the alkyl group substituted in the 2, 3 and 5 positions is isobutyl or isooctyl; o-dihydroxy-~` benzene; and 2, 4, 5-trihydroxybutyrophenone. In the case of phenols such as butylated hydroxy anisole; 2,2'-bis (4-hydroxy-phenyl) propane; 4,4'-butylidenebis (6-tert-butyl-_-cresol);
4,4'-thiobis-(6-tert-butyl-m-cresol); and 2-3 dihydroxynaphtha-lene, improvements are observed at levels between 0.5-5.0~, but ` optimums vary depending upon the phenol and the particular antimony compound.
In addition to the above examples, as reported in my earlier application examples, the combination of several o-; dihydric phenols and liquid antimony tris (isooctyl-~-mercapto-propionate), hereinafter "ATP", were demonstrated. Each of the combinations containing 5% phenol were shelf-stable liquids at ambient temperature. The _-dihydric phenols were 4-tertiary butyl catechol, catechol and 2,3-dihydroxynaphthalene.
As developed above, the antim~ny compound may be liquid in its normal state, i.e., at room temperature and atmo-spheric pressure. Also, the antimony compound may be rendered liquid by the addition of a solvent. In this connection, :
,~ -.
l08173 antimony tris ~lauryl mercaptide) is a pasty solid at ambient temperatures~ A composition of 50% hydrocarbon solvent and 50 antimony tris (lauryl mercaptide) was formulated and at room temperature and ambient pressure was a clear liquid. When a sample of such a composition wa6 tested fo~ ~tability under th~
accelerated p~ocedure described above, a control wlthout phenolic stabilizer became opaque after about 35 minutest Upon the addi-bv weight 4-tion of ~%/ tertiary butyl catechol, and the per~ormance ~f the accelerated tests under the same condition~ aq the control, the phenollc containing compo6ition did not be~m~ ~a~ue ~ntil A
passage of 70 mlnute~ Accordin~ly, liquid antim4ny ~abili~er composltions in a normal ~tate or solvat~ 8t~te ~n b~ ~tabilized in accordance with the prlnciple~ ~ this inv~n~lon.
It is als~ to be unde~tood t~a~ ~h~ ~omponent~ can be used and the benefits of this in~ention can bo achl~ved.
Accordingly, other ~odificatio~ will beco~ pa~on~ in Yiew of the teachings hereln wlthout departing from tha tXu~ spirit and Scope of this invention.
Claims (10)
1. A liquid antimony-based composition, stable under ambient conditions, which consists essentially of, a liquid comprising an antimony organic sulfur-contain-ing compound having the formula RnSbX3-n where R of the formula is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkenyl, mixed aryl-alkyl, and substituted groups thereof, where X of the for-mula is selected from the group consisting of sulfur, SR and SRCOOR', where R of the group SR is selected from alkyl, aryl, mixed aryl-alkyl, and substituted groups thereof, where R of the group SRCOOR' is selected from alkylene, arylene, aralkylene, and substituted groups thereof, wherin R' of the group SRCOOR' is selected from alkyl, aryl, mixed aryl-alkyl, and substituted groups thereof, where n is an integer of 0 to 2, and a minor amount by weight of said compound of a phenol chosen from one of the following groups:
(i) monohydric phenols having alkyl, aryl, alkoxy, aryloxy, alkaryl, aralkyl or other substituted alkyl or aryl con-stituents on the nucleus thereof (ii) meta- and para-dihydric phenols and substituted meta- and para-dihydric phenols (iii) trihydric phenols and substituted trihydric phenols.
(i) monohydric phenols having alkyl, aryl, alkoxy, aryloxy, alkaryl, aralkyl or other substituted alkyl or aryl con-stituents on the nucleus thereof (ii) meta- and para-dihydric phenols and substituted meta- and para-dihydric phenols (iii) trihydric phenols and substituted trihydric phenols.
2. The composition of Claim 1 wherein said phenol is butylated hydroxy-anisole.
3. The composition of Claim 1 which is liquid and shelf-stable at room temperatures for at least several weeks.
4. The composition of Claim 3 wherein said antimony compound is selected from the group consisting of antimony tris (isooctylthioglycolate), antimony tris (isooctylmercaptopro-pionate), dodecylmercaptoantimony bis (isooctylthioglycolate), antimony tris (glycoldimercaptoacetate), and mixtures thereof.
5. The composition of Claim 4 wherein said phenol is butylated hydroxy-anisole.
6. The composition of Claim 1 containing said phenol in an amount of about 0.1 to about 20% by weight of said compound.
7. An antimony-based composition liquid and shelf-stable at room temperatures consisting essentially of, a normally liquid antimony organic sulfur-containing compound having the formula RnSbX3-n where R of the formula is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, cycloalkyl, cycloalkenyl, mixed aryl-alkyl, and substituted groups thereof, wherein X of the formula is selected from the group consisting of sulfur, SR and SRCOOR', where R of the group SR is selected from alkyl, aryl, mixed aryl-alkyl, and substituted groups thereof, where R of the group SRCOOR' is selected from alkylene, arylene, aralkylene, and substituted groups thereof, wherein R' of the group SRCOOR' is selected from alkyl, aryl, mixed aryl-alkyl, and substituted groups thereof, where n is an integer of 0 to 2, and as a stabilizer therefor a minor amount of said compound of a phenol chosen from the group consisting of butylated hydroxy anisole, p-dihydroxy benzene, m-dihydroxy benzene, 2,6-di-t-butyl para cresol, resorcinol monobenzoate, p-octyl phenyl salicylate, mono-isobutyl phenol, di-isobutyl phenol, tri isobutyl phenol, mono-isooctyl phenol, di-isooctyl phenol, tri-isooctyl phenol, 2,4,5-trihydroxy butyrophenone, 2,2'-bis (4-hydrotryphenyl) propane, 4,4'-butylidene-bis (6-tert-butyl-m-cresol), and 4,4' thiobis- (6-tert-butyl-m-cresol).
8. The composition of Claim 7 wherein the relative amount of phenol present is from about 1 to about 20 percent by weight of said antimony compound.
9. The composition of Claim 7 wherein said antimony com-pound is selected from the group consisting of antimony tris (isooctylthioglycolate), antimony tris (isooctylmercaptopro-pionate), dodecylmercaptoantimony bis (isooctylthioglycolate), antimony tris (glycoldimercaptoacetate), and mixtures thereof.
10. The composition of Claim 8 wherein said phenol is butylated hydroxy-anisole.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/805,372 US4158640A (en) | 1975-06-30 | 1977-06-10 | Stable liquid antimony organic sulfur-containing compounds |
US805,372 | 1977-06-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1108173A true CA1108173A (en) | 1981-09-01 |
Family
ID=25191392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA305,116A Expired CA1108173A (en) | 1977-06-10 | 1978-06-09 | Stable liquid antimony organic sulfur-containing compounds |
Country Status (9)
Country | Link |
---|---|
JP (2) | JPS5416428A (en) |
BE (1) | BE867990R (en) |
CA (1) | CA1108173A (en) |
DE (1) | DE2825472C2 (en) |
ES (1) | ES470671A2 (en) |
FR (1) | FR2393828B2 (en) |
GB (1) | GB1586335A (en) |
IT (1) | IT1158748B (en) |
NL (1) | NL7806318A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4231895A (en) * | 1979-01-02 | 1980-11-04 | M & T Chemicals Inc. | Synergistic heat stabilizer compositions containing an antimony or a bismuth compound |
US4303578A (en) * | 1979-04-03 | 1981-12-01 | Ciba-Geigy Corporation | Organo-antimony compounds |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4029618A (en) * | 1975-06-30 | 1977-06-14 | Dart Industries Inc. | Vinyl halide stabilizer compositions of antimony organic sulfur-containing compounds and ortho-dihydric phenols |
-
1978
- 1978-05-31 GB GB24683/78A patent/GB1586335A/en not_active Expired
- 1978-06-08 IT IT24339/78A patent/IT1158748B/en active
- 1978-06-09 DE DE2825472A patent/DE2825472C2/en not_active Expired
- 1978-06-09 CA CA305,116A patent/CA1108173A/en not_active Expired
- 1978-06-09 JP JP6897778A patent/JPS5416428A/en active Pending
- 1978-06-09 BE BE188465A patent/BE867990R/en not_active IP Right Cessation
- 1978-06-09 ES ES470671A patent/ES470671A2/en not_active Expired
- 1978-06-09 NL NL7806318A patent/NL7806318A/en not_active Application Discontinuation
- 1978-06-12 FR FR7817550A patent/FR2393828B2/en not_active Expired
-
1984
- 1984-11-01 JP JP59229063A patent/JPS60144343A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2393828A2 (en) | 1979-01-05 |
BE867990R (en) | 1978-10-02 |
ES470671A2 (en) | 1979-04-01 |
JPS60144343A (en) | 1985-07-30 |
NL7806318A (en) | 1978-12-12 |
GB1586335A (en) | 1981-03-18 |
IT7824339A0 (en) | 1978-06-08 |
FR2393828B2 (en) | 1985-11-15 |
JPS5416428A (en) | 1979-02-07 |
DE2825472C2 (en) | 1982-07-08 |
IT1158748B (en) | 1987-02-25 |
DE2825472A1 (en) | 1978-12-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4158640A (en) | Stable liquid antimony organic sulfur-containing compounds | |
US4912155A (en) | Antioxidant aromatic fluorophosphites | |
EP0155847B1 (en) | A stabilizer for synthetic resins and resins stabilized thereby | |
US5663280A (en) | Carbonate polymer resins containing low volatility aromatic phosphate ester compounds | |
CA1108173A (en) | Stable liquid antimony organic sulfur-containing compounds | |
EP2944644A1 (en) | Spiro bisphosphite based compound and uses of the same | |
US4231895A (en) | Synergistic heat stabilizer compositions containing an antimony or a bismuth compound | |
GB2046762A (en) | Resin stabilizer compositions containing sulphur-containing ester tin compounds and ortho-dihydric phenols | |
US4724247A (en) | Antioxidant aromatic diphosphites | |
JPH10509465A (en) | Stabilizer composition comprising chroman derivative, organic phosphite or phosphonite and amine | |
US4374258A (en) | Chroman-6-ol derivatives useful for stabilizing plastics | |
US3590083A (en) | Alkylthioalkanoylaminophenol antioxidants | |
JPH0641018A (en) | Perfluoroalkyl-substituted hydroxyphenylalkanoate antioxidant | |
EP0076067A2 (en) | Isocyanuric acid derivatives, their preparation and use in stabilizing organic substances | |
US3657321A (en) | 4 4'-alkylidene-diphenol-bis-(di-t-butyl-4'''-hydroxyphenyl) alkanoates | |
CA1190731A (en) | Low toxic polyvinylchloride stabilizers | |
US4906775A (en) | Esters of 3-tert-butyl- and 3-tert-butyl-5-alkyl-4-hydroxyphenyl (alkane) carboxylic acids with oxyethylates of polythiols | |
US4199495A (en) | Thiolcarbonate ester stabilizers | |
US3903160A (en) | Aroylamido bis- and tris-(alkylphenols) | |
KR880007630A (en) | Polyolefin stabilized against oxidative collapse with a mixture of arkal substituted diarylamines and steric hindrance phosphites | |
KR100406620B1 (en) | Phosphites, their preparation methods and uses | |
US4163008A (en) | Dual purpose stabilizer compounds and polymer compositions containing same | |
JPH11349803A (en) | Thermoplastic polyurethane composition and conveyor belt | |
JPS61148287A (en) | Anitoxidant | |
US5229444A (en) | Antioxidant polyolefin compositions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |