CA1090812A - Substituted 1,3-diphenoxypropan-2-o1 derivatives and their manufacture and use - Google Patents

Substituted 1,3-diphenoxypropan-2-o1 derivatives and their manufacture and use

Info

Publication number
CA1090812A
CA1090812A CA280,051A CA280051A CA1090812A CA 1090812 A CA1090812 A CA 1090812A CA 280051 A CA280051 A CA 280051A CA 1090812 A CA1090812 A CA 1090812A
Authority
CA
Canada
Prior art keywords
compound
general formula
formula
propan
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA280,051A
Other languages
English (en)
French (fr)
Inventor
Helmut Grill
Rainer H. Zsochocke
Josef Wagner
Gernot Hofrichter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Deutschland GmbH
Original Assignee
Klinge Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klinge Pharma GmbH and Co filed Critical Klinge Pharma GmbH and Co
Application granted granted Critical
Publication of CA1090812A publication Critical patent/CA1090812A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA280,051A 1976-06-08 1977-06-07 Substituted 1,3-diphenoxypropan-2-o1 derivatives and their manufacture and use Expired CA1090812A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2625688A DE2625688C3 (de) 1976-06-08 1976-06-08 1,3-Diphenoxypropanol-(2)-Derivate sowie Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DEP2625688.2 1976-06-08

Publications (1)

Publication Number Publication Date
CA1090812A true CA1090812A (en) 1980-12-02

Family

ID=5980082

Family Applications (1)

Application Number Title Priority Date Filing Date
CA280,051A Expired CA1090812A (en) 1976-06-08 1977-06-07 Substituted 1,3-diphenoxypropan-2-o1 derivatives and their manufacture and use

Country Status (7)

Country Link
JP (2) JPS537638A (US20090163788A1-20090625-C00002.png)
BE (1) BE855464R (US20090163788A1-20090625-C00002.png)
CA (1) CA1090812A (US20090163788A1-20090625-C00002.png)
DE (1) DE2625688C3 (US20090163788A1-20090625-C00002.png)
FR (1) FR2354312A2 (US20090163788A1-20090625-C00002.png)
GB (1) GB1533820A (US20090163788A1-20090625-C00002.png)
ZA (1) ZA773426B (US20090163788A1-20090625-C00002.png)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567201A (en) * 1981-11-25 1986-01-28 Takeda Chemical Industries, Ltd. Diphenoxypropane derivatives and compositions of antiasthmatic and antiinflammatory agents thereof
US5135940A (en) * 1982-09-23 1992-08-04 Merck Frosst Canada, Inc. Leukotriene antagonists
JPS6020430U (ja) * 1983-07-20 1985-02-13 三菱自動車工業株式会社 スライド式シ−トのレ−ル構造
JPS6043436U (ja) * 1983-08-29 1985-03-27 三菱自動車工業株式会社 スライド式シ−トのレ−ル取付構造
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6124495A (en) 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof

Also Published As

Publication number Publication date
FR2354312B2 (US20090163788A1-20090625-C00002.png) 1981-02-13
DE2625688A1 (de) 1977-12-22
DE2625688B2 (de) 1981-01-15
JPS537638A (en) 1978-01-24
GB1533820A (en) 1978-11-29
BE855464R (fr) 1977-10-03
ZA773426B (en) 1978-05-30
DE2625688C3 (de) 1982-01-28
FR2354312A2 (fr) 1978-01-06
JPS5748136B2 (US20090163788A1-20090625-C00002.png) 1982-10-14
JPS5677244A (en) 1981-06-25

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