CA1090330A - 14.beta.-HYDROXY 3-DEOXYCARDENOLIDES - Google Patents

14.beta.-HYDROXY 3-DEOXYCARDENOLIDES

Info

Publication number
CA1090330A
CA1090330A CA251,508A CA251508A CA1090330A CA 1090330 A CA1090330 A CA 1090330A CA 251508 A CA251508 A CA 251508A CA 1090330 A CA1090330 A CA 1090330A
Authority
CA
Canada
Prior art keywords
beta
hydroxy
group
zinc
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA251,508A
Other languages
English (en)
French (fr)
Inventor
Gunther Kruger
Original Assignee
Steele Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steele Chemicals Co Ltd filed Critical Steele Chemicals Co Ltd
Application granted granted Critical
Publication of CA1090330A publication Critical patent/CA1090330A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
CA251,508A 1975-05-07 1976-04-30 14.beta.-HYDROXY 3-DEOXYCARDENOLIDES Expired CA1090330A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB19144/75A GB1553222A (en) 1975-05-07 1975-05-07 14 - hydroxy 3- eoxycardenolides
GB19144/75 1975-05-07

Publications (1)

Publication Number Publication Date
CA1090330A true CA1090330A (en) 1980-11-25

Family

ID=10124489

Family Applications (1)

Application Number Title Priority Date Filing Date
CA251,508A Expired CA1090330A (en) 1975-05-07 1976-04-30 14.beta.-HYDROXY 3-DEOXYCARDENOLIDES

Country Status (9)

Country Link
US (1) US4102884A (enExample)
JP (1) JPS51136664A (enExample)
CA (1) CA1090330A (enExample)
DE (1) DE2620280A1 (enExample)
DK (1) DK203576A (enExample)
FR (1) FR2310132A1 (enExample)
GB (1) GB1553222A (enExample)
NO (1) NO761569L (enExample)
SE (1) SE7605069L (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234577A (en) * 1979-03-19 1980-11-18 Z-L Limited Partnership Ergostadientriols, compositions containing same, and methods of preparing and using same
US4259240A (en) * 1979-09-28 1981-03-31 Advance Biofactures Corporation Synthesis of furyl intermediates, and cardenolides and their isomers prepared therefrom
CN1047598C (zh) * 1993-07-06 1999-12-22 昆明医学院 达玛烷型皂甙人参低元醇衍生物及制备方法
GB0713463D0 (en) 2007-07-11 2007-08-22 Btg Int Ltd Modulators of hypoxia inducible factor-1 and related uses
US20120310140A1 (en) 2010-12-01 2012-12-06 Spinal Modulation, Inc. Directed delivery of agents to neural anatomy
CN104628807B (zh) * 2015-02-10 2016-09-14 中国科学院上海有机化学研究所 16-烯-20-羟基甾体化合物的合成方法
US20240417425A1 (en) * 2021-12-17 2024-12-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Cardiac steroid derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3087944A (en) * 1959-02-03 1963-04-30 Advance Growth Capital Corp 19-methyl-19-acyloxy strophanthidin derivatives
GB1426170A (en) * 1972-12-27 1976-02-25 Radiochemical Centre Ltd Selenium-75 derivatives of steroids
US3981982A (en) * 1974-09-11 1976-09-21 Abbott Laboratories Radioimmunoassay for determining the digoxin content of a sample

Also Published As

Publication number Publication date
DE2620280A1 (de) 1976-12-02
US4102884A (en) 1978-07-25
FR2310132B1 (enExample) 1981-02-27
SE7605069L (sv) 1976-11-08
GB1553222A (en) 1979-09-26
JPS51136664A (en) 1976-11-26
NO761569L (enExample) 1976-11-09
DK203576A (da) 1976-11-08
FR2310132A1 (fr) 1976-12-03

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