CA1088933A - 15,16-dihydroxyprostaglandins - Google Patents

15,16-dihydroxyprostaglandins

Info

Publication number
CA1088933A
CA1088933A CA291,325A CA291325A CA1088933A CA 1088933 A CA1088933 A CA 1088933A CA 291325 A CA291325 A CA 291325A CA 1088933 A CA1088933 A CA 1088933A
Authority
CA
Canada
Prior art keywords
hydroxy
methyl
trans
carbon atoms
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA291,325A
Other languages
English (en)
French (fr)
Inventor
Paul W. Collins
Raphael Pappo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle and Co of Canada Ltd
Original Assignee
GD Searle and Co of Canada Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle and Co of Canada Ltd filed Critical GD Searle and Co of Canada Ltd
Application granted granted Critical
Publication of CA1088933A publication Critical patent/CA1088933A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA291,325A 1976-11-22 1977-11-21 15,16-dihydroxyprostaglandins Expired CA1088933A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US744,070 1976-11-22
US05/744,070 US4064350A (en) 1976-11-22 1976-11-22 15,16-Dihydroxyprostaglandins

Publications (1)

Publication Number Publication Date
CA1088933A true CA1088933A (en) 1980-11-04

Family

ID=24991309

Family Applications (1)

Application Number Title Priority Date Filing Date
CA291,325A Expired CA1088933A (en) 1976-11-22 1977-11-21 15,16-dihydroxyprostaglandins

Country Status (7)

Country Link
US (1) US4064350A (Direct)
JP (1) JPS5365853A (Direct)
AU (1) AU518594B2 (Direct)
CA (1) CA1088933A (Direct)
DE (1) DE2751920A1 (Direct)
FR (1) FR2371426A1 (Direct)
GB (1) GB1537635A (Direct)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4194055A (en) * 1976-03-03 1980-03-18 American Cyanamid Company 15,16-dioxy prostenoic acids and esters
US4165331A (en) * 1977-03-30 1979-08-21 American Cyanamid Company 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives
US4235797A (en) * 1977-12-08 1980-11-25 American Cyanamid Company Silyl vinyl esters
IT1162731B (it) * 1979-04-10 1987-04-01 Lepetit Spa 16-metil-16-metossi-5,6-diidro-prosta-glandine della serie e1 ad attivita'antisecretoria
GB8512344D0 (en) * 1985-05-15 1985-06-19 May & Baker Ltd Compositions of matter

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS518248A (en) * 1974-07-09 1976-01-23 Yamanouchi Pharma Co Ltd Shinkina 11*15*166 torihidorokishi 99 okisoopurosutajensanno goseiho
GB1538871A (en) * 1975-01-24 1979-01-24 Lepetit Spa Prostaglandins

Also Published As

Publication number Publication date
FR2371426B1 (Direct) 1981-01-23
GB1537635A (en) 1979-01-04
AU3079477A (en) 1979-05-31
AU518594B2 (en) 1981-10-08
JPS5365853A (en) 1978-06-12
US4064350A (en) 1977-12-20
FR2371426A1 (fr) 1978-06-16
DE2751920A1 (de) 1978-05-24

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Legal Events

Date Code Title Description
MKEX Expiry
MKEX Expiry

Effective date: 19971104