CA1082183A - Biologically active tetracyclic diazepino- dibenzazepine and diazepino-dibenzoxazepine compounds - Google Patents

Biologically active tetracyclic diazepino- dibenzazepine and diazepino-dibenzoxazepine compounds

Info

Publication number
CA1082183A
CA1082183A CA287,866A CA287866A CA1082183A CA 1082183 A CA1082183 A CA 1082183A CA 287866 A CA287866 A CA 287866A CA 1082183 A CA1082183 A CA 1082183A
Authority
CA
Canada
Prior art keywords
methyl
dibenz
process according
hexahydro
diazepino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA287,866A
Other languages
English (en)
French (fr)
Inventor
Willem J. Van Der Burg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzona Inc
Original Assignee
Akzona Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzona Inc filed Critical Akzona Inc
Application granted granted Critical
Publication of CA1082183A publication Critical patent/CA1082183A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/20—[b, f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA287,866A 1976-10-02 1977-09-30 Biologically active tetracyclic diazepino- dibenzazepine and diazepino-dibenzoxazepine compounds Expired CA1082183A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7610942A NL7610942A (nl) 1976-10-02 1976-10-02 Werkwijze voor het bereiden van 1,4-diazepine derivaten.
NL76.10942 1976-10-02

Publications (1)

Publication Number Publication Date
CA1082183A true CA1082183A (en) 1980-07-22

Family

ID=19826997

Family Applications (1)

Application Number Title Priority Date Filing Date
CA287,866A Expired CA1082183A (en) 1976-10-02 1977-09-30 Biologically active tetracyclic diazepino- dibenzazepine and diazepino-dibenzoxazepine compounds

Country Status (17)

Country Link
US (1) US4224321A (show.php)
JP (1) JPS5359697A (show.php)
AU (1) AU511572B2 (show.php)
BE (1) BE859279A (show.php)
CA (1) CA1082183A (show.php)
DE (1) DE2744179A1 (show.php)
DK (1) DK142582B (show.php)
ES (1) ES462838A1 (show.php)
FI (1) FI772872A7 (show.php)
FR (1) FR2366292A1 (show.php)
GB (1) GB1567997A (show.php)
HU (1) HU177404B (show.php)
IE (1) IE45587B1 (show.php)
LU (1) LU78208A1 (show.php)
NL (1) NL7610942A (show.php)
SE (1) SE7710958L (show.php)
ZA (1) ZA775472B (show.php)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0618643A2 (pt) 2005-11-09 2011-09-06 Combinatorx Inc composição compreendendo um par de fármacos, composição compreendendo um corticosteróide e um imunossupressor dependente de imunofilina não-esteróide, kits e uso
US7994314B2 (en) 2007-04-11 2011-08-09 N.V. Organon Method for the preparation of an enantiomerically pure benzazepine
EP2133350B1 (en) * 2007-04-11 2016-03-23 Merck Sharp & Dohme B.V. A method for the preparation of an enantiomerically pure benzazepine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129434C (show.php) * 1966-03-12
NL6806701A (show.php) * 1967-05-19 1968-11-20
US3465042A (en) * 1967-07-26 1969-09-02 Sandoz Ag Substituted 2-nitrobenzophenones
NL176458C (nl) * 1972-09-23 1985-04-16 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat en werkwijze voor de bereiding van daartoe geschikte actieve stoffen.

Also Published As

Publication number Publication date
HU177404B (en) 1981-10-28
DK142582B (da) 1980-11-24
FR2366292B1 (show.php) 1980-04-11
NL7610942A (nl) 1978-04-04
US4224321A (en) 1980-09-23
FI772872A7 (fi) 1978-04-03
AU511572B2 (en) 1980-08-28
ES462838A1 (es) 1978-06-01
AU2883877A (en) 1979-03-22
FR2366292A1 (fr) 1978-04-28
BE859279A (fr) 1978-03-30
DK424277A (show.php) 1978-04-03
LU78208A1 (show.php) 1978-01-23
JPS5359697A (en) 1978-05-29
IE45587L (en) 1978-04-02
SE7710958L (sv) 1978-04-03
GB1567997A (en) 1980-05-21
DK142582C (show.php) 1981-07-27
DE2744179A1 (de) 1978-04-06
IE45587B1 (en) 1982-10-06
ZA775472B (en) 1978-07-26

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Legal Events

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