CA1043598A - Combined contact lens and method of manufacturing same - Google Patents
Combined contact lens and method of manufacturing sameInfo
- Publication number
- CA1043598A CA1043598A CA242,523A CA242523A CA1043598A CA 1043598 A CA1043598 A CA 1043598A CA 242523 A CA242523 A CA 242523A CA 1043598 A CA1043598 A CA 1043598A
- Authority
- CA
- Canada
- Prior art keywords
- rod
- hydroxyl
- zone
- contact lens
- containing monomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
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- Eyeglasses (AREA)
Abstract
ABSTRACT OF THE DISCLOSURE
The invention relates to a combined contact lens comprising a zone of hydrophilic material, an aperture in the center of the zone, and a solid body of an optically transparent material fixed in the a?erture. The solid body is made as a rod bonded chemically with the zone. In accordance with the invention, the hydrophilic material is a hydroxyl-containing monomer, and the rod is a polymer which is inactive in water but which swells in the solution of the hydroxyl-containing monomer. The hydrophilic material is chemically bonded to the polymer by fusion. The invention also relates to a method for manufacturing the contact lens which consists of polymerizing a hydroxyl-containing monomer in the presence of a polymerization initiator, a solvent, and a linking agent in a mould. A rod is disposed in the center of the mould, and the rod is made from a polymer inactive in water but swelling in the solution of the starting hydroxyl-containing monomer. Thereby, a blank is formed which consists of a peripheral zone of a hydrophilic material chemically bonded to the rod.
The invention relates to a combined contact lens comprising a zone of hydrophilic material, an aperture in the center of the zone, and a solid body of an optically transparent material fixed in the a?erture. The solid body is made as a rod bonded chemically with the zone. In accordance with the invention, the hydrophilic material is a hydroxyl-containing monomer, and the rod is a polymer which is inactive in water but which swells in the solution of the hydroxyl-containing monomer. The hydrophilic material is chemically bonded to the polymer by fusion. The invention also relates to a method for manufacturing the contact lens which consists of polymerizing a hydroxyl-containing monomer in the presence of a polymerization initiator, a solvent, and a linking agent in a mould. A rod is disposed in the center of the mould, and the rod is made from a polymer inactive in water but swelling in the solution of the starting hydroxyl-containing monomer. Thereby, a blank is formed which consists of a peripheral zone of a hydrophilic material chemically bonded to the rod.
Description
104359~
The present invention relates to medicine, and more particularly to a combined contact lens and a method of man-ufacturing thereof. Said combined contact lens can be used to correct vision in some diseases and pathological conditions of the cornea, for example, keratoconus, astigmatism, cicatrices of the cornea, etc.
Known in the prior art are rigid contact lenses made mostly of polymethylmethacrylate. The method of manufacturing the~e lenses consists in preparing a polymer blank and sub-sequent mechanical processing thereof into the required shap~s.
Despite the fact that rigid lenses ensure the required optical effect they are badly tolerated by patients due to metabolic disorders in the cornea.
Also known in the prior art are contact lenses made of soft hydrophilic materials, mainly of hydroxyethylmethacrylate polymerization products. The method of manufacturing these lenses consists in preparing a polymer blank by polymerization of hydroxyethylmethacrylate in the presence of an initiating agent, for example, benzoyl peroxide, dinitrilazo-bis-isobutyric acid, etc., and also in the presence of a solvent, or without it, and in the presence of a linking "D",agent, e.g. dimethylacrylate ethylene glycol. The polymerization process is effected in a mould, and 10~359~
the blank is then worked mechanically to impart the desired shape thereto.
I The disadvantage inherent in soft contact lenses is ! that in cases with aspheric cornea (astigmatism, cicatrices of the cornea, etc.) the soft contact lens fails to correct the defect of vision since the surface of the lens follows the defective curvature of the cornea.
¦ Known also is a combined contact lens consisting of ? a zone of hydrophilic material with a solid body of an opticallytransparent material fixed in the centre of the inner side of the lens ~facing the eye). The method for manufacturing this lens is similar to those for manufacturing rigid and soft ~ contact lenses. But the combined lens fails to keep the shape ! f the optical surface in cases with aspherical cornea. More-I over, the presence of two refractive media in the optical zone ¦ impairs the image on the retina.
The object of this invention is to provide a combined contact lens that will ensure high optical efficiency and can be well tolerated by the patients.
Said object has been attained by a combined contact lens which consists of a zone of hydrophilic material, an aperture in the centre of said zone, and a solid body of an optically transparent material fixed in said aperture, said solid body being made as a rod bonded chemically with said zone, characterized in that said hydrophilic material comprises a hydroxyl-containing monomer and said transparent material comprises a polymer which is inactive in water but which swells in the solution of said hydroxyl-containing monomer said monomer being chemically bonded to said polymer by fusion.
D
¦ It i9 recommendable to use polyoxyalkylmethacrylate as the hydrophilic material and polymethylmethacrylate as the optically transparent material of the solid body in the proposed ! combined contact len~.
The method for manufacturing the proposed combined contact lens comprise~: polymerizing a hydroxyl-containing monomer in the presence of a polymerization initiator, a solvent, ¦ and a linking agent in the mould, disposing a rod in the centre I o~ said mould, said rod being made from a polymer inactive in water but swelling in the solution of starting hydroxyl-containing monomer, thereby forming a blank comprising a peripheral zone of a hydrophilic material chemically bonded to said rod, and mechanically working said blank.
¦ It is recommendable that polymethylmethacrylate be ¦ used as the polymer to give the rod the required optical and mechanical properties.
It is also recommendable that water should be used as the solvent and that it should be added in a quantity corresponding to the equilibrium swelling of the resulting polymer.
In order to improve elasticity of the zone of the hydrophilic material, hydroxyethylmethacrylate is recommended to be used.
For a better understanding of the invention it will be further illustrated with an exemplary description of the process for preparing the proposed combined contact lens with reference to the appended drawings in which:
D ~
Fig. 1 shows a i~ectional view of a combined contact lens according to the invention' Fig. 2 is a top view of the same lens, and Fig. 3 is a lens according to the invention fixed on the eye of the patient.
The proposed combined lens consists of a zone of hydrophilic material 2 (Figs 1 and 2) and a solid body 1 ~Figs 1 and 2) made in the form of a rod and chemically bonded to said zone inside an aperture.
The proposed contact lens is a convexonconcave shell having variouis radii of curvature of spherical surfaces Rl, R2, R3 and R4 (Fig. 1).
The solid body made in the form of a rod is an optically transparent polymer non-swelling in water, preferably polymethyl-methacrylate, having good mechanical strength, adequate optical properties, and non-toxic. It is recommendable that the material for the hydrophilic zone should be iselected from a series of polymer derivatives of acrylic or methacrylic esters of polyoxy compounds. Preference should be given to polyoxyethylmethacrylate, since it ensures high elasticity and good tolerance of the lens, The hydrophilic zone can be made either of a material having the same swelling ability, or of a combination of materials having different swelling abilities, so that in order to meet various requirements, the hydrophilic zone can be made in the form 104359~
of concentric zones.
The swelling ability of the hydrophilic material can increase from the centre toward periphery to facilitate correct fitting of the lens to the eye-ball and to ensure good tolerance.
The inner surface of the proposed lens should be made so that a certain gap remained between the lens and the cornea 3 of the eye 5 (Fig. 3). The lens can be applied onto the eye so that the hydrophilic material zone should contact the cornea 3 of the eye (Fig. 5), or the sclera 4 (Fig. 3), or both.
The proposed contact lens was tested on six patients with various disea3es of the eye (high myopia, irregular astigmatism, traumatic aphakia, keratoconus). The vision of the patients had been corrected with rigid contact lenses. The attempt proved to be effective from the optical aspect, but failed due to bad tolerance. The effect was with the known hydrophilic contact lenses from the point of view of tolerance, but the acuity of vision remained inadequate.
We tried the proposed contact lenses with these patie~ts and the acuity of ~ision in all cases was at the level only at-tainable with the known rigid lenses (from 0.7 to 1.0 per cent) while the tolerance was much better and the terms of wearing the lenses were much longer.
Clinical tests of the combined contact lenses have shown that they can be used effectively to attain optimum optical effect in various abnormalties of refraction and in pathological `` ~043598 states of the cornea that otherwise drastically impair the power of vision. The tolerance of the proposed lenses i8 good.
The method for preparing the proposed combined contact lens consists in the following. A mould is provided with a rod fixed in its centre. The rod is made of a polymer that is inac-tive toward water but swells well in a solution of the starting hydroxyl-containing monomer. The hydroxyl-containing monomer for example, hydroxyethylmethacrylate, is polymerized in the presence of a linking agen~ taken in a quantity of 0~05 - 5 mole per cent of the solvent, and an initiating agent. Ethylene-glycol dimethacrylate, diethyleneglycol dimethacrylate, or some other linking agents can be used.
Any known initiating agents, e.g. acyl peroxides, esters of peracids, etc., as well as ultraviolet and ionizing radiation can be used to initiate the polymerization process.
Said rod is made from material, preferably polymethyl- -methacrylate, that does not swell in water but swells in a sol-ution of the starting hydroxyl-containing monomer, that ensures fast diffuse union of the hydrophilic and non-hydrophilic portions of the blank.
It is recommendable to use water as the solvent, although mixtures of water with organic solvents, e.g. ethyleneglycol, can also be used. It is aliso necessary that the concentration of the monomer correspond to the concentration of the polymer that is 104359f~
formed out of it in the equilibrium swollen "D" state, This ensures absence of tension in the hydropilic zone and, hence, absence of deformation.
The obtained polymerized blank is worked mechanically by conventional methods into a combined contact lens.
For a better understanding of the invention, the following examples of its practical embodiment are given by way of illustration.
Example 1 A tetrafluoroethylene mould, 17 mm in diameter, with a rod, 6.5 mm in diameter, made from plasticizer-free polymethyl-methacrylate and fixed in the centre of the mould, is filled with 4.8 g of ethyleneglycol monomethacrylate containing 0.16 per cent of ethyleneglycol dimethacrylate, and 8 mg of dicyclohexyl peroxidicarbonate, and then 3.2 ml of water are added.
Polymerization is conducted for ten hours at a temp-erature of 45C, the resulting polymer blank i~ then extracted froln the mould and dried at a temperature of 80C. A combined contact lens i~ manufactured from the blank by mechanical processing.
Example 2 A tetrafluoroethylene mould sirnilar to that used in Example 1 is filled with a mixture of 6.0 g of ethyleneglycol monomethacrylateand 10 ml of dinitrile of azo-bis-isobutyric acid, 0.25 g of diethyleneglycol dimethacrylate, and 3.0 g of water, and poly-104;~598 merization is conducted for 24 hours at a temperature of 60C.The re~ulting blank is then extracted from the mould, dried at a temperature of 80C, and worked mechanically into a com-bined contact lens.
The present invention relates to medicine, and more particularly to a combined contact lens and a method of man-ufacturing thereof. Said combined contact lens can be used to correct vision in some diseases and pathological conditions of the cornea, for example, keratoconus, astigmatism, cicatrices of the cornea, etc.
Known in the prior art are rigid contact lenses made mostly of polymethylmethacrylate. The method of manufacturing the~e lenses consists in preparing a polymer blank and sub-sequent mechanical processing thereof into the required shap~s.
Despite the fact that rigid lenses ensure the required optical effect they are badly tolerated by patients due to metabolic disorders in the cornea.
Also known in the prior art are contact lenses made of soft hydrophilic materials, mainly of hydroxyethylmethacrylate polymerization products. The method of manufacturing these lenses consists in preparing a polymer blank by polymerization of hydroxyethylmethacrylate in the presence of an initiating agent, for example, benzoyl peroxide, dinitrilazo-bis-isobutyric acid, etc., and also in the presence of a solvent, or without it, and in the presence of a linking "D",agent, e.g. dimethylacrylate ethylene glycol. The polymerization process is effected in a mould, and 10~359~
the blank is then worked mechanically to impart the desired shape thereto.
I The disadvantage inherent in soft contact lenses is ! that in cases with aspheric cornea (astigmatism, cicatrices of the cornea, etc.) the soft contact lens fails to correct the defect of vision since the surface of the lens follows the defective curvature of the cornea.
¦ Known also is a combined contact lens consisting of ? a zone of hydrophilic material with a solid body of an opticallytransparent material fixed in the centre of the inner side of the lens ~facing the eye). The method for manufacturing this lens is similar to those for manufacturing rigid and soft ~ contact lenses. But the combined lens fails to keep the shape ! f the optical surface in cases with aspherical cornea. More-I over, the presence of two refractive media in the optical zone ¦ impairs the image on the retina.
The object of this invention is to provide a combined contact lens that will ensure high optical efficiency and can be well tolerated by the patients.
Said object has been attained by a combined contact lens which consists of a zone of hydrophilic material, an aperture in the centre of said zone, and a solid body of an optically transparent material fixed in said aperture, said solid body being made as a rod bonded chemically with said zone, characterized in that said hydrophilic material comprises a hydroxyl-containing monomer and said transparent material comprises a polymer which is inactive in water but which swells in the solution of said hydroxyl-containing monomer said monomer being chemically bonded to said polymer by fusion.
D
¦ It i9 recommendable to use polyoxyalkylmethacrylate as the hydrophilic material and polymethylmethacrylate as the optically transparent material of the solid body in the proposed ! combined contact len~.
The method for manufacturing the proposed combined contact lens comprise~: polymerizing a hydroxyl-containing monomer in the presence of a polymerization initiator, a solvent, ¦ and a linking agent in the mould, disposing a rod in the centre I o~ said mould, said rod being made from a polymer inactive in water but swelling in the solution of starting hydroxyl-containing monomer, thereby forming a blank comprising a peripheral zone of a hydrophilic material chemically bonded to said rod, and mechanically working said blank.
¦ It is recommendable that polymethylmethacrylate be ¦ used as the polymer to give the rod the required optical and mechanical properties.
It is also recommendable that water should be used as the solvent and that it should be added in a quantity corresponding to the equilibrium swelling of the resulting polymer.
In order to improve elasticity of the zone of the hydrophilic material, hydroxyethylmethacrylate is recommended to be used.
For a better understanding of the invention it will be further illustrated with an exemplary description of the process for preparing the proposed combined contact lens with reference to the appended drawings in which:
D ~
Fig. 1 shows a i~ectional view of a combined contact lens according to the invention' Fig. 2 is a top view of the same lens, and Fig. 3 is a lens according to the invention fixed on the eye of the patient.
The proposed combined lens consists of a zone of hydrophilic material 2 (Figs 1 and 2) and a solid body 1 ~Figs 1 and 2) made in the form of a rod and chemically bonded to said zone inside an aperture.
The proposed contact lens is a convexonconcave shell having variouis radii of curvature of spherical surfaces Rl, R2, R3 and R4 (Fig. 1).
The solid body made in the form of a rod is an optically transparent polymer non-swelling in water, preferably polymethyl-methacrylate, having good mechanical strength, adequate optical properties, and non-toxic. It is recommendable that the material for the hydrophilic zone should be iselected from a series of polymer derivatives of acrylic or methacrylic esters of polyoxy compounds. Preference should be given to polyoxyethylmethacrylate, since it ensures high elasticity and good tolerance of the lens, The hydrophilic zone can be made either of a material having the same swelling ability, or of a combination of materials having different swelling abilities, so that in order to meet various requirements, the hydrophilic zone can be made in the form 104359~
of concentric zones.
The swelling ability of the hydrophilic material can increase from the centre toward periphery to facilitate correct fitting of the lens to the eye-ball and to ensure good tolerance.
The inner surface of the proposed lens should be made so that a certain gap remained between the lens and the cornea 3 of the eye 5 (Fig. 3). The lens can be applied onto the eye so that the hydrophilic material zone should contact the cornea 3 of the eye (Fig. 5), or the sclera 4 (Fig. 3), or both.
The proposed contact lens was tested on six patients with various disea3es of the eye (high myopia, irregular astigmatism, traumatic aphakia, keratoconus). The vision of the patients had been corrected with rigid contact lenses. The attempt proved to be effective from the optical aspect, but failed due to bad tolerance. The effect was with the known hydrophilic contact lenses from the point of view of tolerance, but the acuity of vision remained inadequate.
We tried the proposed contact lenses with these patie~ts and the acuity of ~ision in all cases was at the level only at-tainable with the known rigid lenses (from 0.7 to 1.0 per cent) while the tolerance was much better and the terms of wearing the lenses were much longer.
Clinical tests of the combined contact lenses have shown that they can be used effectively to attain optimum optical effect in various abnormalties of refraction and in pathological `` ~043598 states of the cornea that otherwise drastically impair the power of vision. The tolerance of the proposed lenses i8 good.
The method for preparing the proposed combined contact lens consists in the following. A mould is provided with a rod fixed in its centre. The rod is made of a polymer that is inac-tive toward water but swells well in a solution of the starting hydroxyl-containing monomer. The hydroxyl-containing monomer for example, hydroxyethylmethacrylate, is polymerized in the presence of a linking agen~ taken in a quantity of 0~05 - 5 mole per cent of the solvent, and an initiating agent. Ethylene-glycol dimethacrylate, diethyleneglycol dimethacrylate, or some other linking agents can be used.
Any known initiating agents, e.g. acyl peroxides, esters of peracids, etc., as well as ultraviolet and ionizing radiation can be used to initiate the polymerization process.
Said rod is made from material, preferably polymethyl- -methacrylate, that does not swell in water but swells in a sol-ution of the starting hydroxyl-containing monomer, that ensures fast diffuse union of the hydrophilic and non-hydrophilic portions of the blank.
It is recommendable to use water as the solvent, although mixtures of water with organic solvents, e.g. ethyleneglycol, can also be used. It is aliso necessary that the concentration of the monomer correspond to the concentration of the polymer that is 104359f~
formed out of it in the equilibrium swollen "D" state, This ensures absence of tension in the hydropilic zone and, hence, absence of deformation.
The obtained polymerized blank is worked mechanically by conventional methods into a combined contact lens.
For a better understanding of the invention, the following examples of its practical embodiment are given by way of illustration.
Example 1 A tetrafluoroethylene mould, 17 mm in diameter, with a rod, 6.5 mm in diameter, made from plasticizer-free polymethyl-methacrylate and fixed in the centre of the mould, is filled with 4.8 g of ethyleneglycol monomethacrylate containing 0.16 per cent of ethyleneglycol dimethacrylate, and 8 mg of dicyclohexyl peroxidicarbonate, and then 3.2 ml of water are added.
Polymerization is conducted for ten hours at a temp-erature of 45C, the resulting polymer blank i~ then extracted froln the mould and dried at a temperature of 80C. A combined contact lens i~ manufactured from the blank by mechanical processing.
Example 2 A tetrafluoroethylene mould sirnilar to that used in Example 1 is filled with a mixture of 6.0 g of ethyleneglycol monomethacrylateand 10 ml of dinitrile of azo-bis-isobutyric acid, 0.25 g of diethyleneglycol dimethacrylate, and 3.0 g of water, and poly-104;~598 merization is conducted for 24 hours at a temperature of 60C.The re~ulting blank is then extracted from the mould, dried at a temperature of 80C, and worked mechanically into a com-bined contact lens.
Claims (7)
1. A combined contact lens comprising a zone of hydrophilic material, an aperture in the centre of said zone, and a solid body of an optically transparent material fixed in said aperture, said solid body being made as a rod bonded chemically with said zone, characterized in that said hydrophilic material comprises a hydroxyl-containing monomer and said transparent material comprises a polymer which is inactive in water but which swells in the solution of said hydroxyl-containing monomer; said monomer being chemically bonded to said polymer by fusion.
2. A combined contact lens according to claim 1, in which polyoxyalkylmethacrylate is used as the hydrophilic material.
3. A combined contact lens according to claim 1, in which polymethylmethacrylate is used as the optically transparent material of the solid body.
4. A method for manufacturing a contact lens, comprising:
polymerizing a hydroxyl-containing monomer in the presence of a polymerization initiator, a solvent and a linking agent in a mould;
disposing a rod in the centre of said mould, said rod being made from a polymer inactive in water but swelling in the solution of starting hydroxyl-containing monomer;
thereby forming a blank comprising a peripheral zone of a hydrophilic material chemically bonded to said rod, and mechanically working said blank.
polymerizing a hydroxyl-containing monomer in the presence of a polymerization initiator, a solvent and a linking agent in a mould;
disposing a rod in the centre of said mould, said rod being made from a polymer inactive in water but swelling in the solution of starting hydroxyl-containing monomer;
thereby forming a blank comprising a peripheral zone of a hydrophilic material chemically bonded to said rod, and mechanically working said blank.
5. A method according to claim 4, in which polymethylmetha-crylate is used as the material for the rod.
6. A method according to claim 4, in which water is used as the solvent in the polymerization process, water being taken in a quantity corresponding to equilibrium swelling of the polymer.
7. A method according to claim 4, in which hydroxyethyl-methacrylate is used as the hydroxyl-containing monomer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA242,523A CA1043598A (en) | 1975-12-22 | 1975-12-22 | Combined contact lens and method of manufacturing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA242,523A CA1043598A (en) | 1975-12-22 | 1975-12-22 | Combined contact lens and method of manufacturing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1043598A true CA1043598A (en) | 1978-12-05 |
Family
ID=4104833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA242,523A Expired CA1043598A (en) | 1975-12-22 | 1975-12-22 | Combined contact lens and method of manufacturing same |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA1043598A (en) |
-
1975
- 1975-12-22 CA CA242,523A patent/CA1043598A/en not_active Expired
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