CA1034943A - Phenylglycylcephalosporines substituees - Google Patents

Phenylglycylcephalosporines substituees

Info

Publication number
CA1034943A
CA1034943A CA205,811A CA205811A CA1034943A CA 1034943 A CA1034943 A CA 1034943A CA 205811 A CA205811 A CA 205811A CA 1034943 A CA1034943 A CA 1034943A
Authority
CA
Canada
Prior art keywords
phenylglycylcephalosporins
substituted
substituted phenylglycylcephalosporins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA205,811A
Other languages
English (en)
Other versions
CA205811S (en
Inventor
John G. Gleason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Inc
Original Assignee
Smith Kline and French Canada Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Canada Ltd filed Critical Smith Kline and French Canada Ltd
Application granted granted Critical
Publication of CA1034943A publication Critical patent/CA1034943A/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA205,811A 1973-08-01 1974-07-29 Phenylglycylcephalosporines substituees Expired CA1034943A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/384,771 US3953439A (en) 1973-08-01 1973-08-01 Substituted phenylglycylcephalosporins

Publications (1)

Publication Number Publication Date
CA1034943A true CA1034943A (fr) 1978-07-18

Family

ID=23518690

Family Applications (1)

Application Number Title Priority Date Filing Date
CA205,811A Expired CA1034943A (fr) 1973-08-01 1974-07-29 Phenylglycylcephalosporines substituees

Country Status (12)

Country Link
US (1) US3953439A (fr)
JP (1) JPS6046118B2 (fr)
BE (1) BE818108A (fr)
CA (1) CA1034943A (fr)
DE (1) DE2437143A1 (fr)
FR (2) FR2239250B1 (fr)
GB (2) GB1449071A (fr)
HU (1) HU169778B (fr)
IE (1) IE41525B1 (fr)
IL (1) IL45321A (fr)
NL (1) NL7410301A (fr)
ZA (1) ZA744174B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
US4183925A (en) * 1975-03-27 1980-01-15 Pfizer Inc. 7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
US5461827A (en) * 1994-09-02 1995-10-31 Lofton; Nathan Telescoping window bar unit

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3855213A (en) * 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
US3813376A (en) * 1972-08-31 1974-05-28 Bristol Myers Co 7-(o-aminomethylphenyl-acetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
FR2283123B1 (fr) 1982-03-19
IL45321A (en) 1977-10-31
FR2239250A1 (fr) 1975-02-28
HU169778B (fr) 1977-02-28
IL45321A0 (en) 1974-10-22
JPS6046118B2 (ja) 1985-10-14
DE2437143A1 (de) 1975-02-13
US3953439A (en) 1976-04-27
FR2283123A1 (fr) 1976-03-26
NL7410301A (nl) 1975-02-04
IE41525B1 (en) 1980-01-30
BE818108A (fr) 1975-01-27
FR2239250B1 (fr) 1978-08-11
ZA744174B (en) 1975-06-25
IE41525L (en) 1975-02-01
GB1449072A (en) 1976-09-08
JPS50105686A (fr) 1975-08-20
GB1449071A (en) 1976-09-08

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