CA1032539A - 2-amino-6-dialkylaminodihydropyridines, their production, pharmaceutical compositions and methods of use thereof - Google Patents

2-amino-6-dialkylaminodihydropyridines, their production, pharmaceutical compositions and methods of use thereof

Info

Publication number
CA1032539A
CA1032539A CA219,375A CA219375A CA1032539A CA 1032539 A CA1032539 A CA 1032539A CA 219375 A CA219375 A CA 219375A CA 1032539 A CA1032539 A CA 1032539A
Authority
CA
Canada
Prior art keywords
dialkylaminodihydropyridines
amino
production
methods
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA219,375A
Other languages
English (en)
French (fr)
Inventor
Horst Meyer
Friedrich Bossert
Kurt Stoepel
Wulf Vater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA1032539A publication Critical patent/CA1032539A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA219,375A 1974-02-09 1975-02-04 2-amino-6-dialkylaminodihydropyridines, their production, pharmaceutical compositions and methods of use thereof Expired CA1032539A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2406198A DE2406198C2 (de) 1974-02-09 1974-02-09 Verfahren zur Herstellung von neuen 2-Amino-6-dialkylamino-dihydropyridinen

Publications (1)

Publication Number Publication Date
CA1032539A true CA1032539A (en) 1978-06-06

Family

ID=5906982

Family Applications (1)

Application Number Title Priority Date Filing Date
CA219,375A Expired CA1032539A (en) 1974-02-09 1975-02-04 2-amino-6-dialkylaminodihydropyridines, their production, pharmaceutical compositions and methods of use thereof

Country Status (20)

Country Link
US (1) US4004014A (zh)
JP (1) JPS5943460B2 (zh)
AT (1) AT342590B (zh)
BE (1) BE825245A (zh)
CA (1) CA1032539A (zh)
CH (2) CH613446A5 (zh)
DD (1) DD117452A5 (zh)
DE (1) DE2406198C2 (zh)
DK (1) DK44075A (zh)
ES (2) ES434546A1 (zh)
FI (1) FI750324A (zh)
FR (1) FR2260345B1 (zh)
GB (1) GB1498495A (zh)
HU (1) HU168482B (zh)
IE (1) IE40589B1 (zh)
IL (1) IL46593A (zh)
LU (1) LU71813A1 (zh)
NL (1) NL7501430A (zh)
SE (1) SE402458B (zh)
ZA (1) ZA75790B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210687C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
JPS5232217A (en) * 1975-09-05 1977-03-11 Matsushita Electric Ind Co Ltd Ghost eliminating equipment
CA1050587A (en) * 1975-09-30 1979-03-13 Fmc Corporation Rotating gas diffuser
DE2738153A1 (de) * 1977-08-24 1979-03-08 Bayer Ag 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS57171968A (en) * 1981-04-17 1982-10-22 Kyowa Hakko Kogyo Co Ltd 1,4-dihydropyridine derivative
JPS61108258U (zh) * 1984-12-21 1986-07-09
JPH01181681A (ja) * 1988-01-13 1989-07-19 Komori Printing Mach Co Ltd 印刷機のプラウ折り装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860601A (en) * 1972-03-06 1975-01-14 Horst Meyer 2,6-diamino-1,4-dihydropyridine derivatives
DE2210687C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Also Published As

Publication number Publication date
ATA96975A (de) 1977-08-15
SE7501388L (zh) 1975-08-11
FR2260345B1 (zh) 1980-01-11
DD117452A5 (zh) 1976-01-12
US4004014A (en) 1977-01-18
ES434545A1 (es) 1976-12-16
IL46593A0 (en) 1975-04-25
CH605754A5 (zh) 1978-10-13
IE40589B1 (en) 1979-07-04
ES434546A1 (es) 1977-04-01
SE402458B (sv) 1978-07-03
JPS5943460B2 (ja) 1984-10-22
DE2406198C2 (de) 1983-12-15
GB1498495A (en) 1978-01-18
IL46593A (en) 1977-11-30
NL7501430A (nl) 1975-08-12
FR2260345A1 (zh) 1975-09-05
LU71813A1 (zh) 1975-12-09
DK44075A (zh) 1975-10-06
HU168482B (zh) 1976-05-28
CH613446A5 (zh) 1979-09-28
BE825245A (fr) 1975-08-06
DE2406198A1 (de) 1975-08-14
JPS50108268A (zh) 1975-08-26
ZA75790B (en) 1976-02-25
FI750324A (zh) 1975-08-10
IE40589L (en) 1975-08-09
AT342590B (de) 1978-04-10
AU7786375A (en) 1976-08-05

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