CA1018979A - PROCESS FOR THE PREPARATION OF NOVEL 1-(.beta.-CHLOROETHYL)-1-NITROSOUREA DERIVATIVES - Google Patents

PROCESS FOR THE PREPARATION OF NOVEL 1-(.beta.-CHLOROETHYL)-1-NITROSOUREA DERIVATIVES

Info

Publication number
CA1018979A
CA1018979A CA183,395A CA183395A CA1018979A CA 1018979 A CA1018979 A CA 1018979A CA 183395 A CA183395 A CA 183395A CA 1018979 A CA1018979 A CA 1018979A
Authority
CA
Canada
Prior art keywords
chloroethyl
beta
novel
preparation
nitrosourea derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA183,395A
Other languages
French (fr)
Other versions
CA183395S (en
Inventor
Kaichiro Ichikawa
Noriki Ito
Norio Sato
Masuo Murakami
Yoshihiko Oka
Masakatsu Shibata
Tutomu Kawamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10829672A external-priority patent/JPS4966688A/ja
Priority claimed from JP11001672A external-priority patent/JPS4969676A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1018979A publication Critical patent/CA1018979A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA183,395A 1972-10-28 1973-10-15 PROCESS FOR THE PREPARATION OF NOVEL 1-(.beta.-CHLOROETHYL)-1-NITROSOUREA DERIVATIVES Expired CA1018979A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10829672A JPS4966688A (en) 1972-10-28 1972-10-28
JP11001672A JPS4969676A (en) 1972-11-02 1972-11-02

Publications (1)

Publication Number Publication Date
CA1018979A true CA1018979A (en) 1977-10-11

Family

ID=26448222

Family Applications (1)

Application Number Title Priority Date Filing Date
CA183,395A Expired CA1018979A (en) 1972-10-28 1973-10-15 PROCESS FOR THE PREPARATION OF NOVEL 1-(.beta.-CHLOROETHYL)-1-NITROSOUREA DERIVATIVES

Country Status (8)

Country Link
AT (1) AT335462B (en)
CA (1) CA1018979A (en)
CH (1) CH599161A5 (en)
DE (1) DE2351724A1 (en)
ES (1) ES420004A1 (en)
FR (1) FR2204414B1 (en)
GB (1) GB1408353A (en)
NL (1) NL7314785A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020279A2 (en) * 2001-09-05 2003-03-13 Minerva Biotechnologies Corporation Compositions and methods of treatment of cancer

Also Published As

Publication number Publication date
CH599161A5 (en) 1978-05-12
ES420004A1 (en) 1976-10-01
FR2204414B1 (en) 1978-07-28
AT335462B (en) 1977-03-10
FR2204414A1 (en) 1974-05-24
AU6193573A (en) 1975-05-01
ATA877173A (en) 1976-07-15
GB1408353A (en) 1975-10-01
NL7314785A (en) 1974-05-01
DE2351724A1 (en) 1974-05-09

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