CA1018515A - 2,beta., 16.beta.-DIAMINO-ANDROSTANES AND THEIR PREPARATION - Google Patents

2,beta., 16.beta.-DIAMINO-ANDROSTANES AND THEIR PREPARATION

Info

Publication number
CA1018515A
CA1018515A CA186,754A CA186754A CA1018515A CA 1018515 A CA1018515 A CA 1018515A CA 186754 A CA186754 A CA 186754A CA 1018515 A CA1018515 A CA 1018515A
Authority
CA
Canada
Prior art keywords
beta
androstanes
diamino
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA186,754A
Other languages
English (en)
Other versions
CA186754S (en
Inventor
Colin L. Hewett
David S. Savage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzona Inc
Original Assignee
Akzona Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzona Inc filed Critical Akzona Inc
Application granted granted Critical
Publication of CA1018515A publication Critical patent/CA1018515A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA186,754A 1972-11-29 1973-11-27 2,beta., 16.beta.-DIAMINO-ANDROSTANES AND THEIR PREPARATION Expired CA1018515A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5519172A GB1454749A (en) 1972-11-29 1972-11-29 2beta, 16beta-diamino-androstanes and their preparation

Publications (1)

Publication Number Publication Date
CA1018515A true CA1018515A (en) 1977-10-04

Family

ID=10473231

Family Applications (1)

Application Number Title Priority Date Filing Date
CA186,754A Expired CA1018515A (en) 1972-11-29 1973-11-27 2,beta., 16.beta.-DIAMINO-ANDROSTANES AND THEIR PREPARATION

Country Status (18)

Country Link
US (1) US3872091A (US07714131-20100511-C00038.png)
JP (1) JPS546557B2 (US07714131-20100511-C00038.png)
BE (1) BE807988A (US07714131-20100511-C00038.png)
CA (1) CA1018515A (US07714131-20100511-C00038.png)
CH (1) CH605506A5 (US07714131-20100511-C00038.png)
DE (1) DE2359076C2 (US07714131-20100511-C00038.png)
DK (1) DK132500C (US07714131-20100511-C00038.png)
ES (1) ES420922A1 (US07714131-20100511-C00038.png)
FI (1) FI52349C (US07714131-20100511-C00038.png)
FR (1) FR2207724B1 (US07714131-20100511-C00038.png)
GB (1) GB1454749A (US07714131-20100511-C00038.png)
HU (1) HU168724B (US07714131-20100511-C00038.png)
IE (1) IE38513B1 (US07714131-20100511-C00038.png)
NL (1) NL7316237A (US07714131-20100511-C00038.png)
NO (1) NO139088C (US07714131-20100511-C00038.png)
PH (1) PH12359A (US07714131-20100511-C00038.png)
SE (1) SE395460B (US07714131-20100511-C00038.png)
ZA (1) ZA738759B (US07714131-20100511-C00038.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU172521B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh triamino-androstana i chetvertichnykh solejj
ATE921T1 (de) * 1978-09-05 1982-05-15 Akzo N.V. Saeureadditionssalze von 2-beta, 16-beta-bis-piperidino-an drostan-16-beta-monoquaternaeren ammoniumderivaten und diese enthaltende pharmazeutische zusammensetzungen.
IE50675B1 (en) * 1979-12-12 1986-06-11 Akzo Nv Bis-and mono-quaternary ammonium derivatives of 2beta,16beta-dipiperidino-5alpha-androstanes,processes for their preparation and pharmaceutical preparations
IE53463B1 (en) * 1981-06-15 1988-11-23 Akzo Nv Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same
GB8708886D0 (en) * 1987-04-14 1987-05-20 Akzo Nv 2beta-morpholino-androstane derivatives
CZ300694A3 (en) * 1993-12-02 1996-05-15 Akzo Nobel Nv Substituted 2beta-morpholinandrostane derivatives, process of their preparation, their use for preparing pharmaceutical preparations and pharmaceutical compositions containing thereof
US5767112A (en) * 1994-10-21 1998-06-16 Poli Industria Chimica, S.P.A. Muscle relaxant pharmaceutical compositions
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
AU2003205244B2 (en) * 2002-01-18 2009-01-08 Regents Of The University Of Minnesota Triterpene quaternary salts as biologically active surfactants
WO2012147090A1 (en) * 2011-04-26 2012-11-01 Neon Laboratories Ltd. Novel process for quaternization of (2p,3a,5a,16p,17p)-2,16-bispiperidino-3,17-diacetoxy-5-androstane

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
FR1468539A (fr) * 1965-02-19 1967-02-03 Organon Labor Ltd Nouveaux 2beta, 16beta-diamino-androstanes et procédé pour leur préparation

Also Published As

Publication number Publication date
JPS4993353A (US07714131-20100511-C00038.png) 1974-09-05
HU168724B (US07714131-20100511-C00038.png) 1976-07-28
FI52349C (fi) 1977-08-10
ZA738759B (en) 1974-10-30
AU6286273A (en) 1975-05-29
FR2207724A1 (US07714131-20100511-C00038.png) 1974-06-21
BE807988A (fr) 1974-05-29
IE38513L (en) 1974-05-20
SE395460B (sv) 1977-08-15
DK132500C (da) 1976-05-17
FR2207724B1 (US07714131-20100511-C00038.png) 1977-09-02
FI52349B (US07714131-20100511-C00038.png) 1977-05-02
NO139088B (no) 1978-09-25
CH605506A5 (US07714131-20100511-C00038.png) 1978-09-29
NL7316237A (US07714131-20100511-C00038.png) 1974-05-31
ES420922A1 (es) 1976-04-01
DE2359076A1 (de) 1974-06-06
DE2359076C2 (de) 1983-12-08
PH12359A (en) 1979-01-29
JPS546557B2 (US07714131-20100511-C00038.png) 1979-03-29
NO139088C (no) 1979-01-03
US3872091A (en) 1975-03-18
DK132500B (da) 1975-12-15
GB1454749A (en) 1976-11-03
IE38513B1 (en) 1978-03-29

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