CA1014954A - Morphinan derivatives - Google Patents

Morphinan derivatives

Info

Publication number
CA1014954A
CA1014954A CA165,651A CA165651A CA1014954A CA 1014954 A CA1014954 A CA 1014954A CA 165651 A CA165651 A CA 165651A CA 1014954 A CA1014954 A CA 1014954A
Authority
CA
Canada
Prior art keywords
morphinan derivatives
morphinan
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA165,651A
Other languages
English (en)
Other versions
CA165651S (en
Inventor
Willy Leimgruber
Ernest Mohacsi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1014954A publication Critical patent/CA1014954A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA165,651A 1972-03-10 1973-03-08 Morphinan derivatives Expired CA1014954A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23371572A 1972-03-10 1972-03-10
US00299478A US3810899A (en) 1972-03-10 1972-10-20 2-hydroxy-n-substituted-morphinan derivatives

Publications (1)

Publication Number Publication Date
CA1014954A true CA1014954A (en) 1977-08-02

Family

ID=26927165

Family Applications (1)

Application Number Title Priority Date Filing Date
CA165,651A Expired CA1014954A (en) 1972-03-10 1973-03-08 Morphinan derivatives

Country Status (11)

Country Link
US (1) US3810899A (sr)
AU (1) AU475007B2 (sr)
CA (1) CA1014954A (sr)
CH (2) CH586205A5 (sr)
DK (1) DK138988B (sr)
FR (1) FR2181800B1 (sr)
GB (1) GB1402502A (sr)
IL (1) IL41562A (sr)
NL (1) NL7303050A (sr)
PH (1) PH11649A (sr)
SE (1) SE403908B (sr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556712A (en) * 1981-05-20 1985-12-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines
US4410700A (en) * 1980-07-03 1983-10-18 The United States Of America As Represented By The Department Of Health And Human Services Preparation of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines by optical resolution
US4496762A (en) * 1983-03-29 1985-01-29 Eastman Kodak Company Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide
US5905153A (en) * 1996-10-02 1999-05-18 Roche Vitamins Inc. Process for preparing (9α,13α,14α)-1-(3-methoxy-morphinan-17-yl)alkanones
US5849917A (en) * 1996-10-02 1998-12-15 Roche Vitamins Inc. Process for the preparation of isoquinoline compounds
ATE438649T1 (de) * 2006-04-21 2009-08-15 Zach System Spa Verfahren zur herstellung von dorzolamid

Also Published As

Publication number Publication date
AU475007B2 (en) 1976-08-12
DK138988B (da) 1978-11-27
IL41562A (en) 1977-04-29
FR2181800A1 (sr) 1973-12-07
AU5222773A (en) 1974-08-15
DK138988C (sr) 1979-05-07
PH11649A (en) 1978-05-08
FR2181800B1 (sr) 1976-05-14
CH586205A5 (sr) 1977-03-31
IL41562A0 (en) 1973-04-30
GB1402502A (en) 1975-08-13
US3810899A (en) 1974-05-14
CH591449A5 (sr) 1977-09-15
SE403908B (sv) 1978-09-11
NL7303050A (sr) 1973-09-12

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