BRPI0905584B8 - antimalarial pharmaceutical composition containing extract and/or standardized fraction of bark of aspidosperma parvifolium and/or ulein and its derivatives and use - Google Patents

antimalarial pharmaceutical composition containing extract and/or standardized fraction of bark of aspidosperma parvifolium and/or ulein and its derivatives and use

Info

Publication number
BRPI0905584B8
BRPI0905584B8 BRPI0905584A BRPI0905584A BRPI0905584B8 BR PI0905584 B8 BRPI0905584 B8 BR PI0905584B8 BR PI0905584 A BRPI0905584 A BR PI0905584A BR PI0905584 A BRPI0905584 A BR PI0905584A BR PI0905584 B8 BRPI0905584 B8 BR PI0905584B8
Authority
BR
Brazil
Prior art keywords
ulein
aspidosperma
parvifolium
fraction
pharmaceutical composition
Prior art date
Application number
BRPI0905584A
Other languages
Portuguese (pt)
Inventor
Braga De Oliveira Alaíde
Maria Andrade Gomes Fabiana
Dutra Rocha Fabíola
Fani Dolabela Maria
Maria Taveira Neiva Rosa
Lisieux Ribeiro Paiva Jácome Rose
Original Assignee
Univ Minas Gerais
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minas Gerais filed Critical Univ Minas Gerais
Priority to BRPI0905584A priority Critical patent/BRPI0905584B8/en
Publication of BRPI0905584A2 publication Critical patent/BRPI0905584A2/en
Priority to BRBR132012033307-3A priority patent/BR132012033307E2/en
Publication of BRPI0905584B1 publication Critical patent/BRPI0905584B1/en
Publication of BRPI0905584B8 publication Critical patent/BRPI0905584B8/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

extrato e fração padronizados de cascas de aspidosperma parvifolium e sua composição farmacêutica a presente invenção descreve o processo para obtenção de extrato e fração padronizados de aspidosperma parvifolium, popularmente denominada "pau-pereira, guatambu ou peroba", além do isolamento e purificação da uleína. a invenção compreende, ainda, a obtenção de composições farmacêuticas que contêm o extrato, fração derivada e/ou uleína, bem como sua utilização para o tratamento da malária. o extrato, fração e uleína apresentados foram ensaiados e mostraram atividade antiplasmódica, particularmente contra plasmodium falciparum.standardized extract and fraction of aspidosperma parvifolium barks and its pharmaceutical composition the present invention describes the process for obtaining a standardized extract and fraction of aspidosperma parvifolium, popularly called "pau-pereira, guatambu or peroba", in addition to the isolation and purification of ulein. the invention further comprises obtaining pharmaceutical compositions containing the extract, derived fraction and/or ulein, as well as its use for the treatment of malaria. the extract, fraction and ulein presented were tested and showed antiplasmodic activity, particularly against plasmodium falciparum.

BRPI0905584A 2009-12-23 2009-12-23 antimalarial pharmaceutical composition containing extract and/or standardized fraction of bark of aspidosperma parvifolium and/or ulein and its derivatives and use BRPI0905584B8 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BRPI0905584A BRPI0905584B8 (en) 2009-12-23 2009-12-23 antimalarial pharmaceutical composition containing extract and/or standardized fraction of bark of aspidosperma parvifolium and/or ulein and its derivatives and use
BRBR132012033307-3A BR132012033307E2 (en) 2009-12-23 2012-12-27 Pharmaceutical compositions containing extract and / or bark fractions of aspidosperma subincanum and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0905584A BRPI0905584B8 (en) 2009-12-23 2009-12-23 antimalarial pharmaceutical composition containing extract and/or standardized fraction of bark of aspidosperma parvifolium and/or ulein and its derivatives and use

Publications (3)

Publication Number Publication Date
BRPI0905584A2 BRPI0905584A2 (en) 2011-08-23
BRPI0905584B1 BRPI0905584B1 (en) 2021-04-13
BRPI0905584B8 true BRPI0905584B8 (en) 2021-05-25

Family

ID=44484628

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0905584A BRPI0905584B8 (en) 2009-12-23 2009-12-23 antimalarial pharmaceutical composition containing extract and/or standardized fraction of bark of aspidosperma parvifolium and/or ulein and its derivatives and use
BRBR132012033307-3A BR132012033307E2 (en) 2009-12-23 2012-12-27 Pharmaceutical compositions containing extract and / or bark fractions of aspidosperma subincanum and use

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRBR132012033307-3A BR132012033307E2 (en) 2009-12-23 2012-12-27 Pharmaceutical compositions containing extract and / or bark fractions of aspidosperma subincanum and use

Country Status (1)

Country Link
BR (2) BRPI0905584B8 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114560861A (en) * 2022-03-09 2022-05-31 昆明医科大学 Monoterpene indole alkaloid, purification method thereof and application of monoterpene indole alkaloid to drug-resistant bacteria resistance

Also Published As

Publication number Publication date
BRPI0905584A2 (en) 2011-08-23
BR132012033307E2 (en) 2015-07-14
BRPI0905584B1 (en) 2021-04-13

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Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06V Preliminary requirement: patent application procedure suspended [chapter 6.22 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/12/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME MEDIDA CAUTELAR DE 07/04/2021 - ADI 5.529/DF

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/12/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF