BRPI0800496A2 - Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof - Google Patents

Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof

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Publication number
BRPI0800496A2
BRPI0800496A2 BRPI0800496A BRPI0800496A2 BR PI0800496 A2 BRPI0800496 A2 BR PI0800496A2 BR PI0800496 A BRPI0800496 A BR PI0800496A BR PI0800496 A2 BRPI0800496 A2 BR PI0800496A2
Authority
BR
Brazil
Prior art keywords
drug
carnauba wax
pellets
preparation
direct compression
Prior art date
Application number
Other languages
Portuguese (pt)
Inventor
Lima Eliana Martins
De Oliveira Rodinelli Borges
Nascimento Thais Leite
Original Assignee
Univ Fed De Goias Ufg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Fed De Goias Ufg filed Critical Univ Fed De Goias Ufg
Priority to BRPI0800496 priority Critical patent/BRPI0800496A2/en
Publication of BRPI0800496A2 publication Critical patent/BRPI0800496A2/en

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Abstract

PELLETS COM MATRIZ DE CERA DE CARNAúBA COMO UM SISTEMA DE LIBERAçãO CONTìNUA DO FáRMACO, COMO EXCIPIENTE PARA COMPRESSãO DIRETA PARA A PRODUçãO DE COMPRIMIDOS, COMO NúCLEO INERTE PARA UM REVESTIMENTO CONTENDO O FáRMACO E OUTROS CONSTITUINTES E MéTODO DE PREPARAçãO DOS MESMOS. A presente invenção refere-se à pellets produzidas a partir de cera de carnaúba que proporcionam uma liberação contínua do fármaco que está contido na matriz da partícula. Esses pellets também podem estar isentos de um princípio ativo e funcionam como um excipiente para ser utilizado por um técnico no assunto para ajustar a cinética de liberação de um determinado fármaco em uma formulação farmacêutica, e como um núcleo inerte para ser utilizado como um substrato para revestimento sendo que um princípio ativo pode estar contido na camada que recobre a partícula. A invenção também refere-se as formas farmacêuticas constituídas pelos pellets e ao método de preparação destes.CARNAUBA WAX MATTER PELLETS AS A CONTINUOUS RELEASE SYSTEM FOR DRUGS, EXCIPIENT FOR DIRECT COMPRESSION FOR THE PRODUCTION OF TABLETS, AS INERT NUCLEUS CONTAINING DRUG AND OTHER PREPARATIONS OF THE MATERIAL The present invention relates to pellets made from carnauba wax that provide continuous release of the drug that is contained in the particle matrix. Such pellets may also be free of an active ingredient and function as an excipient for use by a person skilled in the art to adjust the release kinetics of a particular drug in a pharmaceutical formulation, and as an inert core to be used as a substrate for coating an active ingredient may be contained in the layer covering the particle. The invention also relates to the dosage forms comprising the pellets and the method of preparation thereof.

BRPI0800496 2008-03-07 2008-03-07 Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof BRPI0800496A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0800496 BRPI0800496A2 (en) 2008-03-07 2008-03-07 Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0800496 BRPI0800496A2 (en) 2008-03-07 2008-03-07 Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof

Publications (1)

Publication Number Publication Date
BRPI0800496A2 true BRPI0800496A2 (en) 2009-11-10

Family

ID=41263729

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0800496 BRPI0800496A2 (en) 2008-03-07 2008-03-07 Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof

Country Status (1)

Country Link
BR (1) BRPI0800496A2 (en)

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Legal Events

Date Code Title Description
B03A Publication of an application: publication of a patent application or of a certificate of addition of invention
B06G Technical and formal requirements: other requirements

Free format text: PARA QUE SEJA ACEITA A PETICAO NO 020110042195 DE 14/03/2011 APRESENTE PETICAO DE DESARQUIVAMENTO DO PEDIDO,EM VIRTUDE DO DISPOSTO NO ART. 33 UNICO DA LPI.

B08E Application fees: requirement for complementation of annuity fee

Free format text: COMPLEMENTAR A RETRIBUICAO DA(S) 9A. ANUIDADE(S), DE ACORDO COM TABELA VIGENTE, REFERENTE A(S) GUIA(S) DE RECOLHIMENTO 22160296852-1.

B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)
B15K Others concerning applications: alteration of classification

Ipc: A61K 9/16 (2006.01), A61K 47/44 (2006.01), A61K 31