BRPI0800496A2 - Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof - Google Patents
Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereofInfo
- Publication number
- BRPI0800496A2 BRPI0800496A2 BRPI0800496A BRPI0800496A2 BR PI0800496 A2 BRPI0800496 A2 BR PI0800496A2 BR PI0800496 A BRPI0800496 A BR PI0800496A BR PI0800496 A2 BRPI0800496 A2 BR PI0800496A2
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- carnauba wax
- pellets
- preparation
- direct compression
- Prior art date
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PELLETS COM MATRIZ DE CERA DE CARNAúBA COMO UM SISTEMA DE LIBERAçãO CONTìNUA DO FáRMACO, COMO EXCIPIENTE PARA COMPRESSãO DIRETA PARA A PRODUçãO DE COMPRIMIDOS, COMO NúCLEO INERTE PARA UM REVESTIMENTO CONTENDO O FáRMACO E OUTROS CONSTITUINTES E MéTODO DE PREPARAçãO DOS MESMOS. A presente invenção refere-se à pellets produzidas a partir de cera de carnaúba que proporcionam uma liberação contínua do fármaco que está contido na matriz da partícula. Esses pellets também podem estar isentos de um princípio ativo e funcionam como um excipiente para ser utilizado por um técnico no assunto para ajustar a cinética de liberação de um determinado fármaco em uma formulação farmacêutica, e como um núcleo inerte para ser utilizado como um substrato para revestimento sendo que um princípio ativo pode estar contido na camada que recobre a partícula. A invenção também refere-se as formas farmacêuticas constituídas pelos pellets e ao método de preparação destes.CARNAUBA WAX MATTER PELLETS AS A CONTINUOUS RELEASE SYSTEM FOR DRUGS, EXCIPIENT FOR DIRECT COMPRESSION FOR THE PRODUCTION OF TABLETS, AS INERT NUCLEUS CONTAINING DRUG AND OTHER PREPARATIONS OF THE MATERIAL The present invention relates to pellets made from carnauba wax that provide continuous release of the drug that is contained in the particle matrix. Such pellets may also be free of an active ingredient and function as an excipient for use by a person skilled in the art to adjust the release kinetics of a particular drug in a pharmaceutical formulation, and as an inert core to be used as a substrate for coating an active ingredient may be contained in the layer covering the particle. The invention also relates to the dosage forms comprising the pellets and the method of preparation thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0800496 BRPI0800496A2 (en) | 2008-03-07 | 2008-03-07 | Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0800496 BRPI0800496A2 (en) | 2008-03-07 | 2008-03-07 | Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0800496A2 true BRPI0800496A2 (en) | 2009-11-10 |
Family
ID=41263729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0800496 BRPI0800496A2 (en) | 2008-03-07 | 2008-03-07 | Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof |
Country Status (1)
Country | Link |
---|---|
BR (1) | BRPI0800496A2 (en) |
-
2008
- 2008-03-07 BR BRPI0800496 patent/BRPI0800496A2/en not_active IP Right Cessation
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TWI507193B (en) | Transdermal delivery patch | |
Roberts et al. | Development and evaluation of sustained-release Compritol® 888 ATO matrix mini-tablets | |
Huang et al. | Salvianolic acid B ameliorates hyperglycemia and dyslipidemia in db/db mice through the AMPK pathway | |
CL2008000823A1 (en) | Immediate release pharmaceutical formulation comprising dapagliflozin propylene glycol hydrate and a pharmaceutically acceptable carrier; Use to treat diabetes, glucose intolerance, insulin resistance, among others. | |
BRPI0822026B8 (en) | pharmaceutical or nutraceutical preparation, tablet, gelatin or hpmc capsule, and use of one or a mixture of a plurality of polymers or copolymers | |
Li et al. | Interactions of the active components of Punica granatum (pomegranate) with the essential renal and hepatic human Solute Carrier transporters | |
AR084865A1 (en) | FAST DISINTEGRATION PREPARATION, DISPERSABLE COMPRESSED BY ORAL ROUTE | |
CO6620043A2 (en) | Method of preparing pharmaceutical compositions intended for oral administration comprising one or more active ingredients and the compositions comprising them | |
Kesarla et al. | Formulation and evaluation of floating tablet of H2-receptor antagonist | |
Gugu et al. | Solid lipid microparticles: An approach for improving oral bioavailability of aspirin | |
Cai et al. | Evaluation of the resistance of a geopolymer-based drug delivery system to tampering | |
TW201016212A (en) | Discoloration suppressed stable pharmaceutical formulation | |
Wu et al. | Catalpol exerts antidepressant-like effects by enhancing anti-oxidation and neurotrophy and inhibiting neuroinflammation via activation of HO-1 | |
Kim et al. | A comparative study between spray-drying and fluidized bed coating processes for the preparation of pramipexole controlled-release microparticles for orally disintegrating tablets | |
CN1935242A (en) | Chinese medicine composition, and its preparing method and quality control method | |
Cao et al. | Photoimages and the release characteristics of lipophilic matrix tablets containing highly water-soluble potassium citrate with high drug loadings | |
Hashem et al. | Formulation and in vitro and in vivo evaluation of lipid-based terbutaline sulphate bi-layer tablets for once-daily administration | |
BRPI0800496A2 (en) | Carnauba wax matrix pellets as a continuous drug release system, as a direct compression excipient for tabletting, as an inert core for a coating containing the drug and other constituents and method of preparation thereof | |
CN105560207A (en) | Naringin controlled release capsule and preparation method thereof | |
Nicholson et al. | Development of oral extended release formulations of 6‐hydroxybuspirone | |
Birhanu et al. | Quality evaluation of the commonly prescribed antipsychotic drugs (chlorpromazine and thioridazine tablets) marketed in Ethiopia | |
Gohel et al. | Modulation of venlafaxine hydrochloride release from press coated matrix tablet | |
Sachan et al. | Thermal stability and drug-excipient compatibility studies of peppermint and caraway oils for formulation of chewable tablets | |
Patil et al. | Development and evaluation of time controlled pulsatile release Lisinopril tablets | |
WO2012068076A3 (en) | Pharmaceutical formulations containing soluble drugs |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B03A | Publication of an application: publication of a patent application or of a certificate of addition of invention | ||
B06G | Technical and formal requirements: other requirements |
Free format text: PARA QUE SEJA ACEITA A PETICAO NO 020110042195 DE 14/03/2011 APRESENTE PETICAO DE DESARQUIVAMENTO DO PEDIDO,EM VIRTUDE DO DISPOSTO NO ART. 33 UNICO DA LPI. |
|
B08E | Application fees: requirement for complementation of annuity fee |
Free format text: COMPLEMENTAR A RETRIBUICAO DA(S) 9A. ANUIDADE(S), DE ACORDO COM TABELA VIGENTE, REFERENTE A(S) GUIA(S) DE RECOLHIMENTO 22160296852-1. |
|
B08F | Application fees: dismissal - article 86 of industrial property law | ||
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) | ||
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 9/16 (2006.01), A61K 47/44 (2006.01), A61K 31 |