BRPI0711948A2 - derivado 39-desmetóxi-39-metil de rapamicina; composto; composição farmacêutica; método para o tratamento do cáncer ou malignidades de célula b, da indução ou manutenção da imunopressão, do tratamento de rejeição de transplante, da doença enxerto versus hospedeiro, dos distúrbios auto-imunes; das doenças de inflamação, da doença vascular e doenças fibróticas, da estimulação da regeneração neuronal ou para o tratamento de infecções por fungos; uso de um composto; processo para preparação de um composto de fórmula (i); e composição ou kit de partes - Google Patents
derivado 39-desmetóxi-39-metil de rapamicina; composto; composição farmacêutica; método para o tratamento do cáncer ou malignidades de célula b, da indução ou manutenção da imunopressão, do tratamento de rejeição de transplante, da doença enxerto versus hospedeiro, dos distúrbios auto-imunes; das doenças de inflamação, da doença vascular e doenças fibróticas, da estimulação da regeneração neuronal ou para o tratamento de infecções por fungos; uso de um composto; processo para preparação de um composto de fórmula (i); e composição ou kit de partes Download PDFInfo
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- BRPI0711948A2 BRPI0711948A2 BRPI0711948-8A BRPI0711948A BRPI0711948A2 BR PI0711948 A2 BRPI0711948 A2 BR PI0711948A2 BR PI0711948 A BRPI0711948 A BR PI0711948A BR PI0711948 A2 BRPI0711948 A2 BR PI0711948A2
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- Brazil
- Prior art keywords
- compound according
- formula
- compound
- treatment
- demethoxy
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0609963.4 | 2006-05-19 | ||
| GBGB0609963.4A GB0609963D0 (en) | 2006-05-19 | 2006-05-19 | Novel compounds |
| PCT/GB2007/001875 WO2007135411A1 (en) | 2006-05-19 | 2007-05-18 | 39-desmethoxy-39-methyl derivatives of rapamycin. |
Publications (1)
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| BRPI0711948A2 true BRPI0711948A2 (pt) | 2011-12-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0711948-8A BRPI0711948A2 (pt) | 2006-05-19 | 2007-05-18 | derivado 39-desmetóxi-39-metil de rapamicina; composto; composição farmacêutica; método para o tratamento do cáncer ou malignidades de célula b, da indução ou manutenção da imunopressão, do tratamento de rejeição de transplante, da doença enxerto versus hospedeiro, dos distúrbios auto-imunes; das doenças de inflamação, da doença vascular e doenças fibróticas, da estimulação da regeneração neuronal ou para o tratamento de infecções por fungos; uso de um composto; processo para preparação de um composto de fórmula (i); e composição ou kit de partes |
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| US (1) | US7897608B2 (https=) |
| EP (1) | EP2027131A1 (https=) |
| JP (1) | JP2009537504A (https=) |
| CN (1) | CN101448841A (https=) |
| AU (1) | AU2007253024A1 (https=) |
| BR (1) | BRPI0711948A2 (https=) |
| CA (1) | CA2651411A1 (https=) |
| GB (1) | GB0609963D0 (https=) |
| MX (1) | MX2008014745A (https=) |
| WO (1) | WO2007135411A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105764501A (zh) | 2013-07-26 | 2016-07-13 | 现代化制药公司 | 改善比生群治疗效益的组合物 |
| MX2016015569A (es) | 2014-06-02 | 2017-04-25 | Children´S Medical Center Corp | Metodos y composiciones para inmunomodulacion. |
| CN106916835B (zh) * | 2015-12-24 | 2022-08-12 | 武汉合生科技有限公司 | 化合物的生物合成基因簇及其应用 |
| CA3223081A1 (en) | 2021-07-15 | 2023-01-19 | Samir Mitragotri | Compositions and methods relating to cells with adhered particles |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA737247B (en) | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
| US5023262A (en) | 1990-08-14 | 1991-06-11 | American Home Products Corporation | Hydrogenated rapamycin derivatives |
| US5221670A (en) | 1990-09-19 | 1993-06-22 | American Home Products Corporation | Rapamycin esters |
| US5138051A (en) | 1991-08-07 | 1992-08-11 | American Home Products Corporation | Rapamycin analogs as immunosuppressants and antifungals |
| WO1992021341A1 (en) | 1991-05-31 | 1992-12-10 | Pfizer Inc. | Use of rapamycin prodrugs as immunosuppressant agents |
| ZA935112B (en) | 1992-07-17 | 1994-02-08 | Smithkline Beecham Corp | Rapamycin derivatives |
| GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
| US5391730A (en) | 1993-10-08 | 1995-02-21 | American Home Products Corporation | Phosphorylcarbamates of rapamycin and oxime derivatives thereof |
| US5378836A (en) | 1993-10-08 | 1995-01-03 | American Home Products Corporation | Rapamycin oximes and hydrazones |
| US5373014A (en) | 1993-10-08 | 1994-12-13 | American Home Products Corporation | Rapamycin oximes |
| US5912253A (en) | 1993-12-17 | 1999-06-15 | Novartis Ag | Rapamycin derivatives |
| US5362718A (en) * | 1994-04-18 | 1994-11-08 | American Home Products Corporation | Rapamycin hydroxyesters |
| US5563145A (en) | 1994-12-07 | 1996-10-08 | American Home Products Corporation | Rapamycin 42-oximes and hydroxylamines |
| US5780462A (en) | 1995-12-27 | 1998-07-14 | American Home Products Corporation | Water soluble rapamycin esters |
| US6015815A (en) | 1997-09-26 | 2000-01-18 | Abbott Laboratories | Tetrazole-containing rapamycin analogs with shortened half-lives |
| JP4547911B2 (ja) * | 2002-02-01 | 2010-09-22 | アリアド・ファーマシューティカルズ・インコーポレイテッド | リン含有化合物およびその用途 |
| CA2492153C (en) * | 2002-07-16 | 2012-05-08 | Biotica Technology Limited | Production of polyketide fkbp-ligand analogues |
| US7160867B2 (en) * | 2003-05-16 | 2007-01-09 | Isotechnika, Inc. | Rapamycin carbohydrate derivatives |
| GB0417852D0 (en) * | 2004-08-11 | 2004-09-15 | Biotica Tech Ltd | Production of polyketides and other natural products |
| GB0504994D0 (en) * | 2005-03-11 | 2005-04-20 | Biotica Tech Ltd | Novel compounds |
-
2006
- 2006-05-19 GB GBGB0609963.4A patent/GB0609963D0/en not_active Ceased
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2007
- 2007-05-18 CN CNA2007800179170A patent/CN101448841A/zh active Pending
- 2007-05-18 AU AU2007253024A patent/AU2007253024A1/en not_active Abandoned
- 2007-05-18 BR BRPI0711948-8A patent/BRPI0711948A2/pt not_active IP Right Cessation
- 2007-05-18 JP JP2009510554A patent/JP2009537504A/ja active Pending
- 2007-05-18 CA CA002651411A patent/CA2651411A1/en not_active Abandoned
- 2007-05-18 MX MX2008014745A patent/MX2008014745A/es not_active Application Discontinuation
- 2007-05-18 EP EP07732896A patent/EP2027131A1/en not_active Withdrawn
- 2007-05-18 WO PCT/GB2007/001875 patent/WO2007135411A1/en not_active Ceased
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2008
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Also Published As
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| US20090176819A1 (en) | 2009-07-09 |
| MX2008014745A (es) | 2009-02-19 |
| EP2027131A1 (en) | 2009-02-25 |
| WO2007135411A1 (en) | 2007-11-29 |
| GB0609963D0 (en) | 2006-06-28 |
| JP2009537504A (ja) | 2009-10-29 |
| AU2007253024A1 (en) | 2007-11-29 |
| US7897608B2 (en) | 2011-03-01 |
| CN101448841A (zh) | 2009-06-03 |
| CA2651411A1 (en) | 2007-11-29 |
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| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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