BRPI0615771A2 - método que compreende administrar a um paciente uma forma de dosagem oral; método para minimizar um efeito colateral adverso associado com a administração de lecozotan a um paciente; método para administrar lecozotan a um paciente; método de tratar doença de alzheimer em um paciente; uso de lecozotan na preparação de um medicamento na forma de dosagem oral; e uso de lecozotan na preparação de um medicamento na forma de dosagem oral para minimizar um efeito colateral adverso associado com a administração de lecozotan a um paciente - Google Patents
método que compreende administrar a um paciente uma forma de dosagem oral; método para minimizar um efeito colateral adverso associado com a administração de lecozotan a um paciente; método para administrar lecozotan a um paciente; método de tratar doença de alzheimer em um paciente; uso de lecozotan na preparação de um medicamento na forma de dosagem oral; e uso de lecozotan na preparação de um medicamento na forma de dosagem oral para minimizar um efeito colateral adverso associado com a administração de lecozotan a um paciente Download PDFInfo
- Publication number
- BRPI0615771A2 BRPI0615771A2 BRPI0615771-8A BRPI0615771A BRPI0615771A2 BR PI0615771 A2 BRPI0615771 A2 BR PI0615771A2 BR PI0615771 A BRPI0615771 A BR PI0615771A BR PI0615771 A2 BRPI0615771 A2 BR PI0615771A2
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- BR
- Brazil
- Prior art keywords
- patient
- lecozotan
- cmax
- dosage form
- average
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- 239000003762 serotonin receptor affecting agent Substances 0.000 description 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 description 1
- 231100000872 sexual dysfunction Toxicity 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 208000019116 sleep disease Diseases 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
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- 239000000725 suspension Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
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- 230000001331 thermoregulatory effect Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71541705P | 2005-09-09 | 2005-09-09 | |
| US60/715,417 | 2005-09-09 | ||
| PCT/US2006/034813 WO2007030589A2 (en) | 2005-09-09 | 2006-09-06 | Pharmaceutical dosage forms and compositions comprising lecoztan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0615771A2 true BRPI0615771A2 (pt) | 2011-05-24 |
Family
ID=37836444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0615771-8A BRPI0615771A2 (pt) | 2005-09-09 | 2006-09-06 | método que compreende administrar a um paciente uma forma de dosagem oral; método para minimizar um efeito colateral adverso associado com a administração de lecozotan a um paciente; método para administrar lecozotan a um paciente; método de tratar doença de alzheimer em um paciente; uso de lecozotan na preparação de um medicamento na forma de dosagem oral; e uso de lecozotan na preparação de um medicamento na forma de dosagem oral para minimizar um efeito colateral adverso associado com a administração de lecozotan a um paciente |
Country Status (17)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8134029B2 (en) | 2002-09-16 | 2012-03-13 | Sunovion Pharmaceuticals Inc. | Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine |
| AU2006264317B2 (en) | 2005-07-06 | 2012-02-23 | Sunovion Pharmaceuticals Inc. | Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
| CA2759180A1 (en) * | 2009-05-13 | 2010-11-18 | Sunovion Pharmaceuticals Inc. | Compositions comprising transnorsertraline and serotonin receptor 1a agonists/antagonists and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1345595T1 (sl) * | 2000-09-29 | 2007-08-31 | Solvay Pharm Bv | Farmacevtska oblika s podaljĺ anim sproĺ äśanjem, ki je neodvisna od ionske jakosti |
| GB2407498B (en) * | 2003-10-30 | 2008-06-11 | Cipla Ltd | Oral formulations for 5-HT receptor agonists with reduced degradation of active ingredient |
| US20050215561A1 (en) * | 2004-03-19 | 2005-09-29 | Krishnendu Ghosh | Pharmaceutical dosage forms and compositions |
| CN101137648A (zh) * | 2005-03-01 | 2008-03-05 | 惠氏公司 | 结晶和非晶4－氰基－n－{(2r)－2－[4－(2,3－二氢－苯并[1,4]二氧杂环己烯－5－基)－哌嗪－1－基]－丙基}－n－吡啶－2－基－苯甲酰胺盐酸盐 |
-
2006
- 2006-09-06 AU AU2006287543A patent/AU2006287543A1/en not_active Abandoned
- 2006-09-06 KR KR1020087007106A patent/KR20080043855A/ko not_active Withdrawn
- 2006-09-06 TW TW095132852A patent/TW200800198A/zh unknown
- 2006-09-06 WO PCT/US2006/034813 patent/WO2007030589A2/en active Application Filing
- 2006-09-06 CA CA002620491A patent/CA2620491A1/en not_active Abandoned
- 2006-09-06 EP EP06790193A patent/EP1928863A2/en not_active Withdrawn
- 2006-09-06 CN CNA2006800328607A patent/CN101258146A/zh active Pending
- 2006-09-06 GT GT200600403A patent/GT200600403A/es unknown
- 2006-09-06 BR BRPI0615771-8A patent/BRPI0615771A2/pt not_active Application Discontinuation
- 2006-09-06 RU RU2008108216/14A patent/RU2008108216A/ru not_active Application Discontinuation
- 2006-09-06 PE PE2006001076A patent/PE20070334A1/es not_active Application Discontinuation
- 2006-09-06 AR ARP060103880A patent/AR058033A1/es unknown
- 2006-09-06 JP JP2008530186A patent/JP2009507850A/ja not_active Withdrawn
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2008
- 2008-02-28 IL IL189827A patent/IL189827A0/en unknown
- 2008-03-03 NO NO20081100A patent/NO20081100L/no not_active Application Discontinuation
- 2008-03-04 EC EC2008008236A patent/ECSP088236A/es unknown
- 2008-03-07 CR CR9800A patent/CR9800A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GT200600403A (es) | 2007-09-19 |
| TW200800198A (en) | 2008-01-01 |
| CN101258146A (zh) | 2008-09-03 |
| CA2620491A1 (en) | 2007-03-15 |
| AR058033A1 (es) | 2008-01-23 |
| IL189827A0 (en) | 2008-11-03 |
| WO2007030589A2 (en) | 2007-03-15 |
| CR9800A (es) | 2008-04-28 |
| RU2008108216A (ru) | 2009-10-20 |
| AU2006287543A1 (en) | 2007-03-15 |
| PE20070334A1 (es) | 2007-05-08 |
| KR20080043855A (ko) | 2008-05-19 |
| EP1928863A2 (en) | 2008-06-11 |
| NO20081100L (no) | 2008-06-03 |
| WO2007030589A3 (en) | 2007-11-01 |
| ECSP088236A (es) | 2008-04-28 |
| JP2009507850A (ja) | 2009-02-26 |
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