BRPI0609905B1 - Uso de derivados de benzotriazol para fotoestabilização e composição cosmética ou dermatológica para melhorar a fotoestabilidade de sistemas absorvedores de UV - Google Patents

Info

Publication number

BRPI0609905B1

BRPI0609905B1 BRPI0609905-0A BRPI0609905A BRPI0609905B1 BR PI0609905 B1 BRPI0609905 B1 BR PI0609905B1 BR PI0609905 A BRPI0609905 A BR PI0609905A BR PI0609905 B1 BRPI0609905 B1 BR PI0609905B1

Authority

BR

Brazil

Prior art keywords

acid

derivative

cosmetic

formula

derivatives

Prior art date

2005-04-28

Links

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• 239000000203 mixture Substances 0.000 title claims abstract description 86
• 239000002537 cosmetic Substances 0.000 title claims abstract description 65
• 125000003354 benzotriazolyl group Chemical class N1N=NC2=C1C=CC=C2* 0.000 title claims abstract 6
• 230000000176 photostabilization Effects 0.000 title claims description 5
• 239000006096 absorbing agent Substances 0.000 claims abstract description 50
• 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 11
• 239000001257 hydrogen Substances 0.000 claims abstract description 10
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract description 4
• NZZIMKJIVMHWJC-UHFFFAOYSA-N dibenzoylmethane Chemical class C=1C=CC=CC=1C(=O)CC(=O)C1=CC=CC=C1 NZZIMKJIVMHWJC-UHFFFAOYSA-N 0.000 claims description 52
• 150000001851 cinnamic acid derivatives Chemical class 0.000 claims description 49
• 125000004432 carbon atom Chemical group C* 0.000 claims description 21
• 125000000217 alkyl group Chemical group 0.000 claims description 13
• 230000000475 sunscreen effect Effects 0.000 claims description 10
• 239000000516 sunscreening agent Substances 0.000 claims description 10
• 238000009472 formulation Methods 0.000 claims description 9
• YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims description 7
• 239000012964 benzotriazole Substances 0.000 claims description 6
• QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 claims description 4
• 229960001679 octinoxate Drugs 0.000 claims description 4
• 229910052799 carbon Inorganic materials 0.000 claims description 3
• OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 2
• 125000004429 atom Chemical group 0.000 claims description 2
• 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 claims description 2
• 125000004400 (C1-C12) alkyl group Chemical group 0.000 claims 1
• 125000000923 (C1-C30) alkyl group Chemical group 0.000 claims 1
• 125000006527 (C1-C5) alkyl group Chemical group 0.000 claims 1
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract description 5
• 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract description 4
• 229910052736 halogen Inorganic materials 0.000 abstract description 2
• 150000002367 halogens Chemical class 0.000 abstract description 2
• 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
• 230000002708 enhancing effect Effects 0.000 abstract 1
• -1 alkyl radicals Chemical class 0.000 description 112
• 238000002360 preparation method Methods 0.000 description 62
• 150000001565 benzotriazoles Chemical class 0.000 description 61
• 239000003921 oil Substances 0.000 description 58
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• GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 24
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• HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 7
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• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 7
• 239000002245 particle Substances 0.000 description 7
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• 230000000087 stabilizing effect Effects 0.000 description 7
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• OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 6
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