BRPI0602496A - use of protease inhibitors isolated from triatoma infestans - Google Patents

use of protease inhibitors isolated from triatoma infestans

Info

Publication number
BRPI0602496A
BRPI0602496A BRPI0602496-3A BRPI0602496A BRPI0602496A BR PI0602496 A BRPI0602496 A BR PI0602496A BR PI0602496 A BRPI0602496 A BR PI0602496A BR PI0602496 A BRPI0602496 A BR PI0602496A
Authority
BR
Brazil
Prior art keywords
triatoma infestans
protease inhibitors
isolated
inhibitors isolated
factor xiia
Prior art date
Application number
BRPI0602496-3A
Other languages
Portuguese (pt)
Inventor
Ivan Torres Nicolau De Campos
Aparecida Sadae Tanaka
Original Assignee
Fundacao De Amparo A Pesquisa
Univ Fed Sao Paulo Unifesp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao De Amparo A Pesquisa, Univ Fed Sao Paulo Unifesp filed Critical Fundacao De Amparo A Pesquisa
Priority to BRPI0602496A priority Critical patent/BRPI0602496B8/en
Publication of BRPI0602496A publication Critical patent/BRPI0602496A/en
Publication of BRPI0602496B1 publication Critical patent/BRPI0602496B1/en
Publication of BRPI0602496B8 publication Critical patent/BRPI0602496B8/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

USO DE INIBIDORES DE PROTEASES ISOLADOS DO TRIATOMA INFESTANS. A presente invenção se refere ao uso de inibidores seletivos para fator XIIa obtidos a partir de uma biblioteca de mutantes de um inibidor de fator XIIa isolado do barbeiro Triatoma infestans para o tratamento de doenças hemorrágicas e trombolíticas, em métodos diagnósticos ou no recobrimento de tubulações e demais superfícies que compõem um sistema de circulação extracorpóreo.USE OF TRIATOMA INFESTANS ISOLATED PROTEASE INHIBITORS. The present invention relates to the use of factor XIIa selective inhibitors obtained from a mutant library of a factor XIIa inhibitor isolated from Triatoma infestans for the treatment of hemorrhagic and thrombolytic diseases, in diagnostic methods or in the coating of pipes and tubes. other surfaces that make up a cardiopulmonary bypass system.

BRPI0602496A 2006-07-03 2006-07-03 use of protease inhibitors isolated from triatoma infestans BRPI0602496B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0602496A BRPI0602496B8 (en) 2006-07-03 2006-07-03 use of protease inhibitors isolated from triatoma infestans

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0602496A BRPI0602496B8 (en) 2006-07-03 2006-07-03 use of protease inhibitors isolated from triatoma infestans

Publications (3)

Publication Number Publication Date
BRPI0602496A true BRPI0602496A (en) 2008-02-26
BRPI0602496B1 BRPI0602496B1 (en) 2017-12-26
BRPI0602496B8 BRPI0602496B8 (en) 2021-05-25

Family

ID=39124765

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0602496A BRPI0602496B8 (en) 2006-07-03 2006-07-03 use of protease inhibitors isolated from triatoma infestans

Country Status (1)

Country Link
BR (1) BRPI0602496B8 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015080629A1 (en) 2013-11-28 2015-06-04 Общество С Ограниченной Ответственностью "Гематологическая Корпорация" High-selectivity contact activation inhibitor based on infestin-4

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015080629A1 (en) 2013-11-28 2015-06-04 Общество С Ограниченной Ответственностью "Гематологическая Корпорация" High-selectivity contact activation inhibitor based on infestin-4
RU2556116C2 (en) * 2013-11-28 2015-07-10 Общество с ограниченной ответственностью "Гематологическая Корпорация" (ООО "ГемаКор") Highly-selective infestin 4-based inhibitor of contact activation

Also Published As

Publication number Publication date
BRPI0602496B1 (en) 2017-12-26
BRPI0602496B8 (en) 2021-05-25

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2157 DE 08/05/2012.

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: REFERENTE AOS DESPACHOS PUBLICADOS NA RPI 2157 DE 08/05/2012 E RPI 2179 DE 09/10/2012.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/12/2017, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/07/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF