BRPI0516030A - tricycles, their manufacture and use as pharmaceutical agents - Google Patents

tricycles, their manufacture and use as pharmaceutical agents

Info

Publication number
BRPI0516030A
BRPI0516030A BRPI0516030-8A BRPI0516030A BRPI0516030A BR PI0516030 A BRPI0516030 A BR PI0516030A BR PI0516030 A BRPI0516030 A BR PI0516030A BR PI0516030 A BRPI0516030 A BR PI0516030A
Authority
BR
Brazil
Prior art keywords
tricycles
manufacture
pharmaceutical agents
compounds
mentioned compounds
Prior art date
Application number
BRPI0516030-8A
Other languages
Portuguese (pt)
Inventor
Guy Georges
Bernhard Goller
Hans-Willi Krell
Klaus-Peter Kuenkele
Anja Limberg
Petra Rueger
Matthias Rueth
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority claimed from PCT/EP2005/010312 external-priority patent/WO2006032519A1/en
Publication of BRPI0516030A publication Critical patent/BRPI0516030A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"TRICICLOS, SUA FABRICAçãO E USO COMO AGENTES FARMACêUTICOS". Os objetos da presente invenção são os compostos da fórmula 1 fórmula 1, seus sais farmaceuticamente aceitáveis, formas enantioméricas, diastereoisómeros, e racematos, a preparação dos compostos supramencionados, medicamentos que os contêm e sua fabricação, bem como o uso dos compostos supramencionados no controle ou prevenção de enfermidades, tais como câncer."TRICYCLES, ITS MANUFACTURING AND USE AS PHARMACEUTICAL AGENTS". The objects of the present invention are the compounds of formula 1, their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers, and racemates, the preparation of the above-mentioned compounds, the medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control. or prevention of diseases such as cancer.

BRPI0516030-8A 2004-09-24 2005-09-23 tricycles, their manufacture and use as pharmaceutical agents BRPI0516030A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04022753 2004-09-24
PCT/EP2005/010312 WO2006032519A1 (en) 2004-09-24 2005-09-23 Tricycles, their manufacture and use as pharmaceutical agents

Publications (1)

Publication Number Publication Date
BRPI0516030A true BRPI0516030A (en) 2008-08-19

Family

ID=34926694

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516030-8A BRPI0516030A (en) 2004-09-24 2005-09-23 tricycles, their manufacture and use as pharmaceutical agents

Country Status (2)

Country Link
CN (1) CN101027055A (en)
BR (1) BRPI0516030A (en)

Also Published As

Publication number Publication date
CN101027055A (en) 2007-08-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.