BRPI0513077A - polymeric adhesive matrix with salified carboxylic groups for transdermal use - Google Patents
polymeric adhesive matrix with salified carboxylic groups for transdermal useInfo
- Publication number
- BRPI0513077A BRPI0513077A BRPI0513077-8A BRPI0513077A BRPI0513077A BR PI0513077 A BRPI0513077 A BR PI0513077A BR PI0513077 A BRPI0513077 A BR PI0513077A BR PI0513077 A BRPI0513077 A BR PI0513077A
- Authority
- BR
- Brazil
- Prior art keywords
- carboxylic groups
- polymeric adhesive
- salified
- adhesive matrix
- transdermal use
- Prior art date
Links
Abstract
MATRIZ ADESIVA POLIMéRICA COM GRUPOS CARBOXìLICOS SALIFICADOS PARA USO TRANSDéRMICO. A presente invenção refere-se a matrizes poliméricas para a liberação controlada de medicamentos para o uso transdérmico tópico compreendendo os copolímeros de ácido acrílico e/ou metacrílico ou ésteres dos mesmos tendo uma Tg mais baixa do que 0°C, cujos grupos carbóxi livres são salificados com bases orgânicas ou inorgânicas compatíveis. As matrizes da invenção permitem preparar sistemas terapêuticas para a liberação controlada de princípios ativas através da via transdérmica, resolvendo assim os problemas de estabilidade, solubilidade e/ou biodisponibilidade do ingrediente ativo dentro da matriz.POLYMERIC ADHESIVE MOTHER WITH SALIFIED CARBOXYLIC GROUPS FOR TRANSDERMIC USE. The present invention relates to controlled release polymeric drug matrices for topical transdermal use comprising the acrylic and / or methacrylic acid copolymers or esters thereof having a Tg lower than 0 ° C, whose free carboxy groups are salified with compatible organic or inorganic bases. The matrices of the invention make it possible to prepare therapeutic systems for the controlled release of active principles via the transdermal route, thereby solving the stability, solubility and / or bioavailability problems of the active ingredient within the matrix.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2004041628 | 2004-08-06 | ||
PCT/EP2005/007293 WO2006012966A1 (en) | 2004-08-06 | 2005-07-06 | Polymeric adhesive matrix with salified carboxylic groups for transdermal use |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0513077A true BRPI0513077A (en) | 2008-04-22 |
Family
ID=39315116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0513077-8A BRPI0513077A (en) | 2004-08-06 | 2005-07-06 | polymeric adhesive matrix with salified carboxylic groups for transdermal use |
Country Status (1)
Country | Link |
---|---|
BR (1) | BRPI0513077A (en) |
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2005
- 2005-07-06 BR BRPI0513077-8A patent/BRPI0513077A/en not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: IBSA FARMACEUTICI ITALIA S.R.L. (IT) |