BRPI0507718A - Pyrazoline derivatives useful for cancer treatment - Google Patents

Pyrazoline derivatives useful for cancer treatment

Info

Publication number
BRPI0507718A
BRPI0507718A BRPI0507718-4A BRPI0507718A BRPI0507718A BR PI0507718 A BRPI0507718 A BR PI0507718A BR PI0507718 A BRPI0507718 A BR PI0507718A BR PI0507718 A BRPI0507718 A BR PI0507718A
Authority
BR
Brazil
Prior art keywords
cancer
treatment
compounds
cancer treatment
derivatives useful
Prior art date
Application number
BRPI0507718-4A
Other languages
Portuguese (pt)
Inventor
Rosa Cuberes Altisen
Jordi Frigola Constansa
Ramon Mangues Bafalluy
Isolda Casanova Rigal
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES200400362A external-priority patent/ES2238923B1/en
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of BRPI0507718A publication Critical patent/BRPI0507718A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

DERIVADOS DE PIRAZOLINA úTEIS PARA O TRATAMENTO DE CáNCER A presente invenção relaciona-se a novos compostos de pirazolina substituídos, composições farmacêuticas contendo tais compostos e o uso destes compostos para o tratamento de câncer, particularmente para o tratamento de câncer cerebral, câncer nos ossos, cãncer labial, câncer da boca, câncer esofageal, câncer de estomago, câncer de fígado, câncer de bexiga, cãncer de pâncreas, câncer de óvario, cârcer cervical, cãncer de pulmão, câncer de mama, cãncer de pele, especialmente para o tratamento de cãncer de cólon e/ou câncer de intestino e/ou câncer de próstata.Useful PIRAZOLINE DERIVATIVES FOR CANCER TREATMENT The present invention relates to novel substituted pyrazoline compounds, pharmaceutical compositions containing such compounds and the use of these compounds for the treatment of cancer, particularly for the treatment of brain cancer, bone cancer, lip cancer, mouth cancer, esophageal cancer, stomach cancer, liver cancer, bladder cancer, pancreatic cancer, ovary cancer, cervical cancer, lung cancer, breast cancer, skin cancer, especially for the treatment of colon cancer and / or bowel cancer and / or prostate cancer.

BRPI0507718-4A 2004-02-16 2005-02-16 Pyrazoline derivatives useful for cancer treatment BRPI0507718A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200400362A ES2238923B1 (en) 2004-02-16 2004-02-16 NEW SUBSTITUTED PIRAZOLINIC DERIVATIVES.
US10/804,695 US20050182119A1 (en) 2004-02-16 2004-03-19 Substituted pyrazoline derivatives
PCT/EP2005/001656 WO2005077910A1 (en) 2004-02-16 2005-02-16 Pyrazoline derivatives useful for the treatment of cancer

Publications (1)

Publication Number Publication Date
BRPI0507718A true BRPI0507718A (en) 2007-07-03

Family

ID=34863166

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507718-4A BRPI0507718A (en) 2004-02-16 2005-02-16 Pyrazoline derivatives useful for cancer treatment

Country Status (9)

Country Link
EP (1) EP1718618A1 (en)
JP (1) JP2007522180A (en)
KR (1) KR20070044799A (en)
AU (1) AU2005212833A1 (en)
BR (1) BRPI0507718A (en)
CA (1) CA2556478A1 (en)
NO (1) NO20064185L (en)
RU (1) RU2006133150A (en)
WO (1) WO2005077910A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008308473A (en) * 2007-06-18 2008-12-25 Japan Health Science Foundation Cancer-treating agent
CN101735150B (en) * 2009-12-16 2011-12-28 南京大学 Thiourea derivatives containing pyrromonazole ring, preparation method and use thereof
CN101759695B (en) * 2009-12-30 2011-09-14 南京大学 Thiazole derivative containing pyrazole ring and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE361748T1 (en) * 1999-06-16 2007-06-15 Univ Temple 1-(4-SULFAMYLPHENYL)-3-TRIFLUORMETHYL-5-ARYL-2-PYRAZOLINE AS CYCLOOXYGENASE-2 INHIBITORS
ES2174757B1 (en) * 2001-04-06 2003-11-01 Esteve Labor Dr EMPLOYMENT OF FIRAZOLIN DERIVATIVES IN THE PREPARATION OF A MEDICINAL PRODUCT FOR THE PREVENTION AND / OR TREATMENT OF CELLULAR PROLIFERATIVE DISEASES.

Also Published As

Publication number Publication date
AU2005212833A1 (en) 2005-08-25
RU2006133150A (en) 2008-04-10
JP2007522180A (en) 2007-08-09
WO2005077910A1 (en) 2005-08-25
KR20070044799A (en) 2007-04-30
NO20064185L (en) 2006-11-13
CA2556478A1 (en) 2005-08-25
EP1718618A1 (en) 2006-11-08

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 4A, 5A E 6A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2099 DE 29/03/2011.