BRPI0507588A - therapeutic agents, subject vaccination method against microorganism or microorganism-produced antigen, purified culture of salmonella species and their use - Google Patents
therapeutic agents, subject vaccination method against microorganism or microorganism-produced antigen, purified culture of salmonella species and their useInfo
- Publication number
- BRPI0507588A BRPI0507588A BRPI0507588-2A BRPI0507588A BRPI0507588A BR PI0507588 A BRPI0507588 A BR PI0507588A BR PI0507588 A BRPI0507588 A BR PI0507588A BR PI0507588 A BRPI0507588 A BR PI0507588A
- Authority
- BR
- Brazil
- Prior art keywords
- microorganism
- therapeutic agents
- method against
- vaccination method
- salmonella species
- Prior art date
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Agentes terapêuticos, método de vacinação de sujeito contra microrganismo ou antígeno produzido por microrganismo, cultura purificada de espécie de salmonella e respectivo uso Resumo A presente invenção relaciona-se com culturas de Salmonella vivas atenuadas para uso como vacinas. As culturas de Salmonella da presente invenção têm uma capacidade substancialmente reduzida de crescer e replicar na presença de bílis. A capacidade reduzida de crescimento é devida a mutação de desvio metabólico induzida por exposição a uma combinação de ácido nalidíxico e rifampicina por um tempo e sob condições suficientes para induzir a mutação.Therapeutic Agents, Subject Vaccination Method against Microorganism or Microorganism-Produced Antigen, Purified Salmonella Species Culture and Their Use Summary The present invention relates to live attenuated Salmonella cultures for use as vaccines. Salmonella cultures of the present invention have a substantially reduced ability to grow and replicate in the presence of bile. Reduced growth capacity is due to mutation of metabolic shift induced by exposure to a combination of nalidixic acid and rifampicin for a time and under conditions sufficient to induce the mutation.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2004900679A AU2004900679A0 (en) | 2004-02-12 | A therapeutic agent | |
AU00400675 | 2004-02-12 | ||
PCT/AU2005/000187 WO2005078068A1 (en) | 2004-02-12 | 2005-02-14 | Live attenuated salmonella for use as vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0507588A true BRPI0507588A (en) | 2007-07-03 |
Family
ID=38198548
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0507588-2A BRPI0507588A (en) | 2004-02-12 | 2005-02-14 | therapeutic agents, subject vaccination method against microorganism or microorganism-produced antigen, purified culture of salmonella species and their use |
Country Status (1)
Country | Link |
---|---|
BR (1) | BRPI0507588A (en) |
-
2005
- 2005-02-14 BR BRPI0507588-2A patent/BRPI0507588A/en not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |