BRPI0501290A - Group A hemolytic beta streptococcal vaccine, and process for obtaining - Google Patents

Group A hemolytic beta streptococcal vaccine, and process for obtaining

Info

Publication number
BRPI0501290A
BRPI0501290A BRPI0501290A BRPI0501290A BR PI0501290 A BRPI0501290 A BR PI0501290A BR PI0501290 A BRPI0501290 A BR PI0501290A BR PI0501290 A BRPI0501290 A BR PI0501290A
Authority
BR
Brazil
Prior art keywords
group
obtaining
lymphocytes
patients
beta
Prior art date
Application number
Other languages
Portuguese (pt)
Inventor
Luiza Guilherme Guglielmi
Jorge Elias Kalil Jr
Original Assignee
Fundacao Zerbini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao Zerbini filed Critical Fundacao Zerbini
Priority to BRPI0501290 priority Critical patent/BRPI0501290A/en
Publication of BRPI0501290A publication Critical patent/BRPI0501290A/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"VACINA CONTRA O ESTREPTOCOCO BETA HEMOLìTICO DO GRUPO A, E RESPECTIVO PROCESSO DE OBTENçãO". Que prevê a identificação molecular seq³encial de epitopos da região C-terminal da proteína M (20 a 50 resíduos), diferindo em 01 resíduo de aminoácido, identificados por anticorpos e linfócitos T de seres humanos sadios e de pacientes portadores de febre reumática capazes de gerar resposta protetora por anticorpos dependentes de linfócitos T; a prevenção de desenvolvimento de doença auto-imune pelo epitopo selecionado foi avaliada in vitro com linfócitos T provenientes de tecido cardíaco de pacientes com lesões decorrentes da febre reumática."VACCINE AGAINST HEMOLYTIC BETA STREPTOCOCUS OF GROUP A, AND THEIR OBTAINING PROCESS". Predicting sequential molecular identification of M-protein C-terminal epitopes (20 to 50 residues), differing by 01 amino acid residues, identified by antibodies and T lymphocytes from healthy humans and from patients with rheumatic fever capable of generating protective response by T lymphocyte-dependent antibodies; The prevention of autoimmune disease development by the selected epitope was evaluated in vitro with T lymphocytes from cardiac tissue of patients with rheumatic fever lesions.

BRPI0501290 2005-03-24 2005-03-24 Group A hemolytic beta streptococcal vaccine, and process for obtaining BRPI0501290A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0501290 BRPI0501290A (en) 2005-03-24 2005-03-24 Group A hemolytic beta streptococcal vaccine, and process for obtaining

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0501290 BRPI0501290A (en) 2005-03-24 2005-03-24 Group A hemolytic beta streptococcal vaccine, and process for obtaining

Publications (1)

Publication Number Publication Date
BRPI0501290A true BRPI0501290A (en) 2005-12-06

Family

ID=35431765

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0501290 BRPI0501290A (en) 2005-03-24 2005-03-24 Group A hemolytic beta streptococcal vaccine, and process for obtaining

Country Status (1)

Country Link
BR (1) BRPI0501290A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2099481A1 (en) * 2006-11-30 2009-09-16 Fundacão Zerbini Vaccin against group a beta hemolytic streptococcus and respective process for obtaining thereof
US9289485B2 (en) 2006-11-30 2016-03-22 Luiza Guilherme Guglielmi Therapeutic application of S. pyogenes C-terminal peptide

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2099481A1 (en) * 2006-11-30 2009-09-16 Fundacão Zerbini Vaccin against group a beta hemolytic streptococcus and respective process for obtaining thereof
EP2099481A4 (en) * 2006-11-30 2012-12-12 Luiza Guiherme Guglielmi Vaccin against group a beta hemolytic streptococcus and respective process for obtaining thereof
US8642049B2 (en) 2006-11-30 2014-02-04 Luiza Guilherme Guglielmi Vaccine against group A beta hemolytic streptococcus and respective process for obtaining thereof
US9289485B2 (en) 2006-11-30 2016-03-22 Luiza Guilherme Guglielmi Therapeutic application of S. pyogenes C-terminal peptide

Similar Documents

Publication Publication Date Title
Abdel‐Aal et al. Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist
CY1118880T1 (en) HUMAN ANTI-IL-23 ANTIBODIES, COMPOSITIONS, METHODS AND USES
NZ246059A (en) Synthetic polypeptides with at least one antigenic site of a prion protein, methods of their use and manufacture, antibodies thereto, compositions and kits
ATE440861T1 (en) IMMUNIZATION AGAINST CHLAMYDIA PNEUMONIAE
ATE283289T1 (en) MONOCLONAL ANTIBODIES, ANTIGENS AND DIAGNOSIS AND THERAPY OF MALIGNANT DISEASES
EA200701911A1 (en) CHEMERIC RECOMBINANT ANTIGENS OF TOXOPLASMA GONDII
Grencis et al. Immunization of mice with surface antigens from the muscle larvae of Trichinella spiralis
IL172854A0 (en) Autologous self-tolerance inducing cells of monocytic origin and their use in pharmaceutical preparations
ECSP055551A (en) VACCINE COMPOSITIONS CONTAINING AMILOID BETA 1-6 ANTIGEN ARRANGEMENTS
ATE375391T1 (en) CHLAMYDIA ANTIGENS AND CORRESPONDING DNA FRAGMENTS AND THEIR USES
BR0310042A (en) Mucosal combination vaccines for bacterial meningitis
BR0213941A (en) Antigen Arrangements for the Treatment of Bone Disease
Seong et al. Neutralization epitopes on the antigenic domain II of the Orientia tsutsugamushi 56-kDa protein revealed by monoclonal antibodies
BRPI0501290A (en) Group A hemolytic beta streptococcal vaccine, and process for obtaining
DE602006009077D1 (en) HIV EPITOPES AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
BRPI0604997A (en) group A hemolytic beta streptococcal vaccine and its procedure for obtaining
Li et al. Immune response and protective efficacy against homologous challenge in BALB/c mice vaccinated with DNA vaccine encoding Toxoplasma gondii actin depolymerizing factor gene
AR004567A1 (en) METHODS TO DETECT THE T. CRUZI INFECTION, IN A BIOLOGICAL SAMPLE, A RECOMBINANT VECTOR OF EXPRESSION, A MODIFIED MICROORGANISM, A DIAGNOSTIC KIT, A PHARMACEUTICAL COMPOSITION FOR THE PREPARATION OF A MEDICINE PRODUCTION OF ANTIBODIES THAT LINK TO T. CRUZI.
AU6653096A (en) Hybrid protein comprising t-helper cell stimulating epitopes and b-cell epitopes from the major outer membrane protein of chlamydia trachomatis and its use as a vaccine
Etlinger Carrier sequence selection—one key to successful vaccines
ATE552860T1 (en) ANTIBODY VACCINE CONJUGATES AND USES THEREOF
ATE360642T1 (en) MHC CLASS I PEPTIDE EPITOPES OF HUMAN TUMOR-ASSOCIATED ANTIGEN 5T4
BRPI0407727A (en) human lymphocyte vaccine adjuvant
BR9808251A (en) Protective protein or antigenic fragment thereof, a process that uses an ex vivo challenge or animal model, isolated nucleotide sequence or its complementary sequence, host cell or expression system or vector, recombinant protein, vaccine, use of a protein or fragment of same, process to test a vaccine, antibody, diagnostic test, and use of a vaccine.
DK1146889T3 (en) Identification of Specific Differentially Expressed Mycobacterial Antigens and Medical Use of Mycobacterium Proteins Rv0068 and Rv3407

Legal Events

Date Code Title Description
B03B Publication of an application: anticipated publication
B15G Others concerning applications: unknown petition

Free format text: NAO CONHECIDO DA PETICAO NO 018060004614/SP DE 18/01/2006 O SERVICO DE EXAME, UMA VEZ QUE HA PEDIDO DE EXAME ANTERIOR VALIDO, EM VIRTUDE DO DISPOSTO NO ART. 219 INCISO II DA LPI.

B25A Requested transfer of rights approved

Owner name: LUIZA GUILHERME GUGLIELMI (BR/SP) , JORGE ELIAS KA

Free format text: TRANSFERIDO DE: FUNDACAO ZERBINI

B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07D Technical examination (opinion) related to article 229 of industrial property law
B07E Notice of approval relating to section 229 industrial property law

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal
B09B Decision: refusal

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL