BRPI0410636A - virtual representation of nucleotide sequences - Google Patents

virtual representation of nucleotide sequences

Info

Publication number
BRPI0410636A
BRPI0410636A BRPI0410636-9A BRPI0410636A BRPI0410636A BR PI0410636 A BRPI0410636 A BR PI0410636A BR PI0410636 A BRPI0410636 A BR PI0410636A BR PI0410636 A BRPI0410636 A BR PI0410636A
Authority
BR
Brazil
Prior art keywords
genome
probes
virtual representation
algorithm
nucleotide sequences
Prior art date
Application number
BRPI0410636-9A
Other languages
Portuguese (pt)
Inventor
Michael H Wigler
John Healy
Robert Lucito
Original Assignee
Cold Spring Harbor Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Lab filed Critical Cold Spring Harbor Lab
Publication of BRPI0410636A publication Critical patent/BRPI0410636A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"REPRESENTAçãO VIRTUAL DE SEQüêNCIAS DE NUCLEOTìDEO". A presente invenção refere-se a sondas de oligonucleotídeo que podem ser usadas para se hibridizarem a uma representação de seqüências de ácido nucléico. As composições que contêm as sondas tais como micro-arranjos também são fornecidas. A invenção também fornece processos para a utilização destas sondas e composições em aplicações terapêuticas, para diagnóstico e para pesquisa. São fornecidos sistemas e os processos para a utilização de um algoritmo de contagem de palavras que possa rapidamente e com precisão contar o número de vezes em que aparece uma cadeia de caracteres (isto é, nucleotídeos) em particular em uma seqüência de nucleotídeo (por exemplo, um genoma). Este algoritmo pode ser usado para identificar as sondas de oligonucleotídeo da invenção. O algoritmo usa uma transformada de um genoma e uma estrutura de dados auxiliares para contar o número de vezes em que ocorre uma palavra em particular no genoma."VIRTUAL REPRESENTATION OF NUCLEOTIDE SEQUENCES". The present invention relates to oligonucleotide probes that can be used to hybridize to a representation of nucleic acid sequences. Compositions containing probes such as microarray are also provided. The invention also provides methods for using these probes and compositions in therapeutic, diagnostic and research applications. Systems and processes are provided for using a word counting algorithm that can quickly and accurately count the number of times a particular string (i.e. nucleotide) appears in a nucleotide sequence (e.g. , a genome). This algorithm can be used to identify the oligonucleotide probes of the invention. The algorithm uses a genome transform and auxiliary data structure to count the number of times a particular word occurs in the genome.

BRPI0410636-9A 2003-05-23 2004-05-21 virtual representation of nucleotide sequences BRPI0410636A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47284503P 2003-05-23 2003-05-23
US47284303P 2003-05-23 2003-05-23
PCT/US2004/016060 WO2005035792A2 (en) 2003-05-23 2004-05-21 Counting exact word matches in genomes

Publications (1)

Publication Number Publication Date
BRPI0410636A true BRPI0410636A (en) 2006-07-18

Family

ID=34437245

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410636-9A BRPI0410636A (en) 2003-05-23 2004-05-21 virtual representation of nucleotide sequences

Country Status (13)

Country Link
US (1) US8694263B2 (en)
EP (1) EP1631690A2 (en)
JP (1) JP2006525814A (en)
KR (1) KR20060103813A (en)
AU (1) AU2004280531B2 (en)
BR (1) BRPI0410636A (en)
CA (1) CA2526810A1 (en)
GE (1) GEP20125384B (en)
IL (1) IL172093A0 (en)
NO (1) NO20056160L (en)
NZ (1) NZ544235A (en)
RU (1) RU2390561C2 (en)
WO (1) WO2005035792A2 (en)

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Also Published As

Publication number Publication date
AU2004280531B2 (en) 2010-03-25
RU2005140278A (en) 2006-06-27
US20050032095A1 (en) 2005-02-10
WO2005035792A2 (en) 2005-04-21
US8694263B2 (en) 2014-04-08
WO2005035792A3 (en) 2006-03-09
RU2390561C2 (en) 2010-05-27
CA2526810A1 (en) 2005-04-21
AU2004280531A1 (en) 2005-04-21
KR20060103813A (en) 2006-10-04
NZ544235A (en) 2009-12-24
JP2006525814A (en) 2006-11-16
EP1631690A2 (en) 2006-03-08
GEP20125384B (en) 2012-01-25
NO20056160L (en) 2006-02-23
IL172093A0 (en) 2009-02-11

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2206 DE 16/04/2013.