BRPI0407088A - N-arylheteroaromatic products, compositions containing same and their use - Google Patents

N-arylheteroaromatic products, compositions containing same and their use

Info

Publication number
BRPI0407088A
BRPI0407088A BR0407088-7A BRPI0407088A BRPI0407088A BR PI0407088 A BRPI0407088 A BR PI0407088A BR PI0407088 A BRPI0407088 A BR PI0407088A BR PI0407088 A BRPI0407088 A BR PI0407088A
Authority
BR
Brazil
Prior art keywords
products
compositions containing
arylheteroaromatic
containing same
same
Prior art date
Application number
BR0407088-7A
Other languages
Portuguese (pt)
Inventor
Alain Le-Brun
Fabienne Thompson
Gilles Tiraboschi
Patrick Mailliet
Joseph M Salvino
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0300894A external-priority patent/FR2850379B1/en
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of BRPI0407088A publication Critical patent/BRPI0407088A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

"PRODUTOS N-ARIL-HETEROAROMáTICOS, COMPOSIçõES CONTENDO OS MESMOS E SEU USO". Produtos N-aril-heteroaromáticos, composições contendo os mesmos e sua utilização. A presente invenção refere-se a novos compostos químicos, particularmente novos produtos N-aril-heteroaromáticos, composições contendo os mesmos e sua utilização como medicamentos, em particular em oncologia."N-Aryl-Heteroaromatic Products, Compositions Containing the Same and Their Use". N-arylheteroaromatic products, compositions containing same and their use. The present invention relates to novel chemical compounds, particularly novel N-arylheteroaromatic products, compositions containing them and their use as medicaments, in particular in oncology.

BR0407088-7A 2003-01-28 2004-01-26 N-arylheteroaromatic products, compositions containing same and their use BRPI0407088A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0300894A FR2850379B1 (en) 2003-01-28 2003-01-28 N-ARYL-HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR0313086 2003-11-07
PCT/FR2004/000168 WO2004078732A1 (en) 2003-01-28 2004-01-26 N-aryl heteroaromatic products, compositions containing same and use thereof

Publications (1)

Publication Number Publication Date
BRPI0407088A true BRPI0407088A (en) 2006-01-24

Family

ID=32963981

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0407088-7A BRPI0407088A (en) 2003-01-28 2004-01-26 N-arylheteroaromatic products, compositions containing same and their use

Country Status (7)

Country Link
EP (1) EP1590329A1 (en)
JP (1) JP2006516656A (en)
AU (1) AU2004218260A1 (en)
BR (1) BRPI0407088A (en)
CA (1) CA2512243A1 (en)
MX (1) MXPA05008099A (en)
WO (1) WO2004078732A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2525325A1 (en) * 2003-05-01 2004-11-18 Abbott Laboratories Pyrazole-amides and sulfonamides as sodium channel modulators
MX2007008279A (en) * 2005-01-25 2008-02-15 Epix Delaware Inc Substituted arylamine compounds and their use as 5-ht6 modulators.
TW200800946A (en) * 2005-08-15 2008-01-01 Astrazeneca Ab Substituted piperazines as metabotropic glutamate receptor antagonists
US20090281097A1 (en) * 2006-04-14 2009-11-12 Takeda Pharmaceutical Company Limited Nitrogen-containing heterocyclic compound
CN100444842C (en) * 2006-11-30 2008-12-24 四川大学华西医院 Use of N-aryl heterocyclics
KR20100095430A (en) * 2007-11-02 2010-08-30 메틸진 인크. Inhibitors of histone deacetylase
CN101597278B (en) 2008-06-04 2013-04-17 中国中化股份有限公司 Amide-type compound as well as preparation method and application thereof
WO2010001258A2 (en) * 2008-06-30 2010-01-07 Centre National De La Recherche Scientifique Inhibition of tumour growth and metastases
AU2009285591B2 (en) * 2008-08-29 2015-08-27 Treventis Corporation Compositions and methods of treating amyloid disease
MX2012014958A (en) 2010-06-15 2013-02-12 Bayer Ip Gmbh Anthranilic acid diamide derivatives.
WO2012031383A1 (en) 2010-09-06 2012-03-15 中国科学院广州生物医药与健康研究院 Amide compounds
US8362004B2 (en) * 2010-09-08 2013-01-29 Bristol-Myers Squibb Company Piperazine analogs as broad-spectrum influenza antivirals
US9289365B2 (en) * 2011-10-24 2016-03-22 Avon Products, Inc. Compositions and methods for stimulating collagen synthesis in the skin
WO2013171334A1 (en) * 2012-05-18 2013-11-21 Vironova Ab Methanethione compounds having antiviral activity
US9676734B2 (en) 2012-05-18 2017-06-13 Vironova Influenza Ab Compounds and methods
CN106257976B (en) 2014-03-07 2021-02-02 拜奥克里斯特制药公司 Human plasma kallikrein inhibitors
WO2015190613A1 (en) * 2014-06-09 2015-12-17 Takeda Pharmaceutical Company Limited Radiolabeled compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129129A (en) * 1984-11-28 1986-06-17 Kureha Chem Ind Co Ltd Antitumor agent
TW312694B (en) * 1994-09-26 1997-08-11 Daiichi Seiyaku Co
AU713171B2 (en) * 1996-06-29 1999-11-25 Samjin Pharmaceutical Co., Ltd. Piperazine derivatives and process for the preparation thereof
DE10035928A1 (en) * 2000-07-21 2002-03-07 Asta Medica Ag New heteroaryl derivatives and their use as medicines
DE10035908A1 (en) * 2000-07-21 2002-03-07 Asta Medica Ag New heteroaryl derivatives and their use as medicines
MXPA03011886A (en) * 2001-07-05 2005-03-07 Lundbeck & Co As H Composite dosage forms having an inlaid portion.
WO2004002965A1 (en) * 2002-06-29 2004-01-08 Zentaris Gmbh Arylcarbonylpiperazines and heteroarylcarbonylpiperazines and the use thereof for treating benign and malignant tumour diseases

Also Published As

Publication number Publication date
JP2006516656A (en) 2006-07-06
MXPA05008099A (en) 2005-09-21
WO2004078732A1 (en) 2004-09-16
AU2004218260A1 (en) 2004-09-16
EP1590329A1 (en) 2005-11-02
WO2004078732B1 (en) 2004-10-28
CA2512243A1 (en) 2004-09-16

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired