BRPI0406776A - Composição farmacêutica, método de avaliação fisiológica e uso de pelo menos um dentre um inibidor de uma molécula semelhante a resistina (alfa) (relm(alfa)), uma molécula semelhante a resistina ß (relmß), um regulador de expressão de relm(alfa) ou um regulador de expressão de relmß - Google Patents
Composição farmacêutica, método de avaliação fisiológica e uso de pelo menos um dentre um inibidor de uma molécula semelhante a resistina (alfa) (relm(alfa)), uma molécula semelhante a resistina ß (relmß), um regulador de expressão de relm(alfa) ou um regulador de expressão de relmßInfo
- Publication number
- BRPI0406776A BRPI0406776A BR0406776-2A BRPI0406776A BRPI0406776A BR PI0406776 A BRPI0406776 A BR PI0406776A BR PI0406776 A BRPI0406776 A BR PI0406776A BR PI0406776 A BRPI0406776 A BR PI0406776A
- Authority
- BR
- Brazil
- Prior art keywords
- relm
- alpha
- resistin
- regulator
- expression
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2026—IL-4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2086—IL-13 to IL-16
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pathology (AREA)
- Marine Sciences & Fisheries (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
Abstract
"COMPOSIçãO FARMACêUTICA, MéTODO DE AVALIAçãO FISIOLóGICA E USO DE PELO MENOS UM DENTRE UM INIBIDOR DE UMA MOLéCULA SEMELHANTE A RESISTINA A (RELM<244>), uma molécula semelhante a RESISTINA <225> (RELM<225>), UM REGULADOR DE EXPRESSãO DE RELMA OU UM REGULADOR DE EXPRESSãO DE RELM<225>". Composição e método para alívio de uma resposta alérgica por regulação da expressão de moléculas <244> ou <225> semelhantes a resistina (RELM<244> ou RELM<225>). As RELMs são também reveladas como marcadores para avaliação do estado alérgico do paciente, por exemplo, monitorando a inflamação e/ou a restauração tecidular no pulmão ou nas vias aéreas do paciente asmático. A regulação das RELMs está envolvida na patogênese da inflamação alérgica pulmonar e outras condições induzidas por alérgenos. A constatação do envolvimento da RELM<244> e RELM<225> na asma liga, do ponto de vista de mecanismos, a patogênese da resistência à insulina e obesidade, conhecidas como envolvendo RELMs, à asma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44092203P | 2003-01-18 | 2003-01-18 | |
PCT/US2004/001139 WO2004067026A1 (en) | 2003-01-18 | 2004-01-16 | Regulation of allergen induced gene |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0406776A true BRPI0406776A (pt) | 2005-12-27 |
Family
ID=32825146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0406776-2A BRPI0406776A (pt) | 2003-01-18 | 2004-01-16 | Composição farmacêutica, método de avaliação fisiológica e uso de pelo menos um dentre um inibidor de uma molécula semelhante a resistina (alfa) (relm(alfa)), uma molécula semelhante a resistina ß (relmß), um regulador de expressão de relm(alfa) ou um regulador de expressão de relmß |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040198686A1 (pt) |
EP (1) | EP1594525A1 (pt) |
JP (1) | JP2006517962A (pt) |
AU (1) | AU2004207476A1 (pt) |
BR (1) | BRPI0406776A (pt) |
CA (1) | CA2512808A1 (pt) |
WO (1) | WO2004067026A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5229866B2 (ja) * | 2007-12-12 | 2013-07-03 | 国立大学法人広島大学 | 大腸癌、動脈硬化症、又はメタボリックシンドロームの検出方法 |
CA2722668A1 (en) * | 2008-04-29 | 2009-11-05 | Wyeth Llc | Methods for treating inflammation |
EP2858679B2 (en) * | 2012-06-08 | 2024-06-05 | Translate Bio, Inc. | Pulmonary delivery of mrna to non-lung target cells |
US20230003743A1 (en) * | 2020-02-24 | 2023-01-05 | The Children's Medical Center Corporation | Methods and compositions for treating or preventing an allergy or anaphylaxis |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU643427B2 (en) * | 1988-10-31 | 1993-11-18 | Immunex Corporation | Interleukin-4 receptors |
MX9700764A (es) * | 1994-07-29 | 1997-05-31 | Smithkline Beecham Plc | Compuestos novedosos. |
NZ512942A (en) * | 1998-12-14 | 2004-01-30 | Univ Johns Hopkins | Polynucleotides encoding the IL-13 binding chains of the interleukin receptor, pharmaceutical compositions comprising the protein and methods of identifying inhibitors |
AU2001268232A1 (en) * | 2000-06-09 | 2001-12-24 | The Trustees Of The University Of Pennsylvania | Compositions, methods, and kits relating to resistin-like molecules |
JP2002338537A (ja) * | 2001-05-16 | 2002-11-27 | Mitsubishi Pharma Corp | アミド化合物およびその医薬用途 |
AU2003241182A1 (en) * | 2002-06-05 | 2003-12-22 | Asahi Kasei Pharma Corporation | Stat6 activation gene |
-
2004
- 2004-01-16 WO PCT/US2004/001139 patent/WO2004067026A1/en not_active Application Discontinuation
- 2004-01-16 JP JP2006502860A patent/JP2006517962A/ja active Pending
- 2004-01-16 AU AU2004207476A patent/AU2004207476A1/en not_active Abandoned
- 2004-01-16 CA CA002512808A patent/CA2512808A1/en not_active Abandoned
- 2004-01-16 US US10/759,658 patent/US20040198686A1/en not_active Abandoned
- 2004-01-16 EP EP04702963A patent/EP1594525A1/en not_active Withdrawn
- 2004-01-16 BR BR0406776-2A patent/BRPI0406776A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20040198686A1 (en) | 2004-10-07 |
AU2004207476A1 (en) | 2004-08-12 |
EP1594525A1 (en) | 2005-11-16 |
JP2006517962A (ja) | 2006-08-03 |
WO2004067026A1 (en) | 2004-08-12 |
WO2004067026A8 (en) | 2004-10-21 |
CA2512808A1 (en) | 2004-08-12 |
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Legal Events
Date | Code | Title | Description |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |