BR9917326A - Compound, process for producing a compound, and pharmaceutical composition - Google Patents
Compound, process for producing a compound, and pharmaceutical compositionInfo
- Publication number
- BR9917326A BR9917326A BR9917326-3A BR9917326A BR9917326A BR 9917326 A BR9917326 A BR 9917326A BR 9917326 A BR9917326 A BR 9917326A BR 9917326 A BR9917326 A BR 9917326A
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- compound
- pyridyl
- alkoxy
- pharmaceutical composition
- Prior art date
Links
Landscapes
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"COMPOSTO, PROCESSO PARA PRODUZIR UM COMPOSTO, E, COMPOSIçãO FARMACêUTICA". A presente invenção provê novos derivados de catecol hidrazona de fórmula (I) ou seus sais farmaceuticamente aceitáveis, em que R^ 1^ é C~ 1-7~ alquila OU C~ 3-7~ cicloalquila; R~ 2~ é hidrogênio, hidróxi, C~ 1- 5~ alquila ou -CH~ 2~-CH~ 2~-CHC(=O)NH~ 2~; R^ 3^ e R^ 4^ são independentemente hidrogênio, C~ 1-7~ alquila, -C(=X)R^ 5^, OU 2-, 3- ou 4-piridila, pirimidila ou fenila substituída por um ou dois selecionados de um grupo consistindo de halogênio, C~ 1-6~-alcóxi, nitro, trifuorometila, C~ 1-6~ alquila e carboxila ou R^ 3^ e R^ 4^ são diretamente ligados por C~ 3-4~contendo oxigênio, enxofre ou nitrogênio, para formar um anel heterocíclico, X é oxigênio, enxofre ou NH e R^ 5^ é C~ 1-7~ alquila, -NHR^ 6^, CONH~ 2~ ou 2-, 3- ou 4-piridila, pirimidila ou fenila substituída por um selecionado de um grupo consistindo de halogênio, C~ 1-6~ alcóxi, nitrila, trifluorometila, C~ 1-6~ alquila e carboxila, e R^ 6^ é hidrogênio, hidróxi, NH~ 2~, C~ 1- 5~ alcóxi, C~ 1- 5~ alquila, piridila ou fenila."COMPOUND, PROCESS TO PRODUCE A COMPOUND, AND PHARMACEUTICAL COMPOSITION". The present invention provides new hydrazone catechol derivatives of formula (I) or their pharmaceutically acceptable salts, wherein R 1 is C ~ 1-7 ~ alkyl OR C ~ 3-7 ~ cycloalkyl; R ~ 2 ~ is hydrogen, hydroxy, C ~ 1- 5 ~ alkyl or -CH ~ 2 ~ -CH ~ 2 ~ -CHC (= O) NH ~ 2 ~; R ^ 3 ^ and R ^ 4 ^ are independently hydrogen, C ~ 1-7 ~ alkyl, -C (= X) R ^ 5 ^, OU 2-, 3- or 4-pyridyl, pyrimidyl or phenyl substituted by one or two selected from a group consisting of halogen, C ~ 1-6 ~ alkoxy, nitro, trifluoromethyl, C ~ 1-6 ~ alkyl and carboxyl or R ^ 3 ^ and R ^ 4 ^ are directly linked by C ~ 3-4 ~ containing oxygen, sulfur or nitrogen, to form a heterocyclic ring, X is oxygen, sulfur or NH and R ^ 5 ^ is C ~ 1-7 ~ alkyl, -NHR ^ 6 ^, CONH ~ 2 ~ or 2-, 3 - or 4-pyridyl, pyrimidyl or phenyl substituted by one selected from a group consisting of halogen, C ~ 1-6 ~ alkoxy, nitrile, trifluoromethyl, C ~ 1-6 ~ alkyl and carboxyl, and R ^ 6 ^ is hydrogen, hydroxy, NH ~ 2 ~, C ~ 1- 5 ~ alkoxy, C ~ 1- 5 ~ alkyl, pyridyl or phenyl.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR9917326-3A BR9917326A (en) | 1999-05-28 | 1999-05-28 | Compound, process for producing a compound, and pharmaceutical composition |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR9917326-3A BR9917326A (en) | 1999-05-28 | 1999-05-28 | Compound, process for producing a compound, and pharmaceutical composition |
| PCT/KR1999/000264 WO2000073280A1 (en) | 1999-05-28 | 1999-05-28 | Cathecol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9917326A true BR9917326A (en) | 2002-04-23 |
Family
ID=25665523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9917326-3A BR9917326A (en) | 1999-05-28 | 1999-05-28 | Compound, process for producing a compound, and pharmaceutical composition |
Country Status (1)
| Country | Link |
|---|---|
| BR (1) | BR9917326A (en) |
-
1999
- 1999-05-28 BR BR9917326-3A patent/BR9917326A/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: CJ CHEILJEDANG CORP. (KR) Free format text: TRANSFERIDO DE: CHEIL JEDANG CORPORATION |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA DE INT.CL: C07D 239/42, A61K 31/15, C07C 251/86, C07C 281/04, C07C 281/14, C07C 337/08, C07D 213/18, C07D 215/42, C07D 233/52, C07D 295/28 Ipc: C07D 213/53 (2009.01), C07D 215/42 (2009.01), C07D |
|
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |