BR9916746A - Antiinflammatory compounds that inhibit cell adhesion - Google Patents
Antiinflammatory compounds that inhibit cell adhesionInfo
- Publication number
- BR9916746A BR9916746A BR9916746-8A BR9916746A BR9916746A BR 9916746 A BR9916746 A BR 9916746A BR 9916746 A BR9916746 A BR 9916746A BR 9916746 A BR9916746 A BR 9916746A
- Authority
- BR
- Brazil
- Prior art keywords
- cell adhesion
- inhibit cell
- compounds
- antiinflammatory compounds
- formula
- Prior art date
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
"COMPOSTOS ANTIINFLAMATóRIOS QUE INIBEM ADESãO DE CéLULA". Os compostos possuindo a fórmula (I) são úteis para o tratamento de inflamação. Também são reveladas composições farmacêuticas compreendendo os compostos da fórmula (I) e processos para inibir/tratar doenças inflamatórias em um mamífero."ANTI-INFLAMMATORY COMPOUNDS THAT INHIBIT CELL ADHESION". The compounds having formula (I) are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising the compounds of formula (I) and processes for inhibiting / treating inflammatory diseases in a mammal.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/325,336 US6232320B1 (en) | 1998-06-04 | 1999-06-03 | Cell adhesion-inhibiting antiinflammatory compounds |
PCT/US1999/014596 WO2000075145A1 (en) | 1999-06-03 | 1999-06-28 | Cell adhesion-inhibiting antiinflammatory compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9916746A true BR9916746A (en) | 2005-01-11 |
Family
ID=56289920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9916746-8A BR9916746A (en) | 1999-06-03 | 1999-06-28 | Antiinflammatory compounds that inhibit cell adhesion |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP2004509059A (en) |
BR (1) | BR9916746A (en) |
CA (1) | CA2390948A1 (en) |
Families Citing this family (33)
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EP1745050A1 (en) * | 2004-05-04 | 2007-01-24 | F.Hoffmann-La Roche Ag | Thienopyridines as ikk inhibitors |
AU2005238178A1 (en) * | 2004-05-04 | 2005-11-10 | F. Hoffmann-La Roche Ag | Thienopyridazines as IKK inhibitors |
JP2008501758A (en) | 2004-06-09 | 2008-01-24 | グラクソ グループ リミテッド | Pyrrolopyridine derivatives |
EP1773826A4 (en) * | 2004-07-02 | 2009-06-03 | Exelixis Inc | C-met modulators and method of use |
GB0420719D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
GB0420722D0 (en) | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
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AR059898A1 (en) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | DERIVATIVES OF 3-CIANO-PIRIDONA 1,4-DISUSTITUTED AND ITS USE AS ALLOSTERIC MODULATORS OF MGLUR2 RECEIVERS |
EP2004656B1 (en) * | 2006-04-07 | 2013-07-10 | Boehringer Ingelheim International GmbH | Thienopyrimidines having mnk1 /mnk2 inhibiting activity for pharmaceutical compositions |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
KR20100080597A (en) | 2007-09-14 | 2010-07-09 | 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 | 1,3-disubstituted-4-phenyl-1h-pyridin-2-ones |
KR101520086B1 (en) | 2007-09-14 | 2015-05-14 | 얀센 파마슈티칼스 인코포레이티드 | 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1'H-[1,4']bipyridinyl-2'-ones |
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JP5433582B2 (en) | 2007-11-14 | 2014-03-05 | ジャンセン ファーマシューティカルズ, インコーポレイテッド. | Imidazo [1,2-a] pyridine derivatives and their use as positive allosteric modulators of the mGluR2 receptor |
US8697689B2 (en) | 2008-10-16 | 2014-04-15 | Janssen Pharmaceuticals, Inc. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
US8691813B2 (en) | 2008-11-28 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
BRPI1012870B8 (en) | 2009-05-12 | 2021-05-25 | Addex Pharmaceuticals Sa | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors and pharmaceutical composition |
PT2649069E (en) | 2010-11-08 | 2015-11-20 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
AU2011328203B2 (en) | 2010-11-08 | 2015-03-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US9012448B2 (en) | 2010-11-08 | 2015-04-21 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
CN104936963B (en) * | 2012-11-20 | 2017-11-28 | 普罗齐纳斯有限公司 | Sulfide derivative as kinases inhibitor |
CA2900302C (en) * | 2013-02-19 | 2018-07-03 | Pfizer Inc. | Azabenzimidazole compounds as inhibitors of pde4 isozymes for the treatment of cns and other disorders |
JP6320506B2 (en) * | 2013-03-12 | 2018-05-09 | セルジーン クオンティセル リサーチ,インク. | Histone demethylase inhibitor |
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JO3367B1 (en) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE COMPOUNDS AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
ME03518B (en) | 2014-01-21 | 2020-04-20 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
KR102502485B1 (en) | 2014-01-21 | 2023-02-21 | 얀센 파마슈티카 엔.브이. | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
KR101551313B1 (en) | 2014-07-28 | 2015-09-09 | 충남대학교산학협력단 | Novel indene derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating blindness related diseases containing the same as an active ingredient |
GB201520499D0 (en) | 2015-11-20 | 2016-01-06 | Medical Res Council Technology | Compounds |
CN113855670B (en) * | 2021-11-03 | 2023-06-09 | 上海市肺科医院 | Application of A205804 in preparation of medicines for treating sepsis |
CN114950492B (en) * | 2022-05-31 | 2023-09-08 | 安徽大学 | 1, 2-diaminoanthraquinone-molybdenum disulfide composite antibacterial material for photoelectrocatalysis to kill bacteria |
CN117682974B (en) * | 2024-02-02 | 2024-04-16 | 济南悟通生物科技有限公司 | Preparation method of 2-propionyl-1-pyrroline |
-
1999
- 1999-06-28 JP JP2001502427A patent/JP2004509059A/en not_active Withdrawn
- 1999-06-28 BR BR9916746-8A patent/BR9916746A/en not_active Application Discontinuation
- 1999-06-28 CA CA002390948A patent/CA2390948A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2004509059A (en) | 2004-03-25 |
CA2390948A1 (en) | 2000-12-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |