BR9915965A - Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation - Google Patents

Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation

Info

Publication number
BR9915965A
BR9915965A BR9915965-1A BR9915965A BR9915965A BR 9915965 A BR9915965 A BR 9915965A BR 9915965 A BR9915965 A BR 9915965A BR 9915965 A BR9915965 A BR 9915965A
Authority
BR
Brazil
Prior art keywords
smooth muscle
acetal
inhibitors
cell proliferation
muscle cell
Prior art date
Application number
BR9915965-1A
Other languages
Portuguese (pt)
Inventor
Christian Scott Mayer
Paul Jeffrey Dollings
Robert Emmett Mcdevitt
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of BR9915965A publication Critical patent/BR9915965A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção: <B>"BENZILMALTOSìDEOS DE ACETAL COMO INIBIDORES DA PROLIFERAçãO CELULAR DO MúSCULO LISO"<D>. Esta invenção fornece inibidores da proliferação celular do músculo liso de fórmula (I), tendo a estrutura (I), em que X, R^ 1^, R^ 2^, R^ 3^, R^ 4^, R^ 5^, R^ 6^, R^ 7^, R^ 8^ e R^ 9^ têm os significados dados nas reivindicações e descrição.Invention Patent: <B> "BENZYLMALTHOSIDS OF ACETAL AS CELLULAR PROLIFERATION OF THE SMOOTH MUSCLE" <D>. This invention provides smooth muscle cell proliferation inhibitors of formula (I), having structure (I), wherein X, R ^ 1 ^, R ^ 2 ^, R ^ 3 ^, R ^ 4 ^, R ^ 5 ^, R ^ 6 ^, R ^ 7 ^, R ^ 8 ^ and R ^ 9 ^ have the meanings given in the claims and description.

BR9915965-1A 1998-11-24 1999-11-23 Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation BR9915965A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19880398A 1998-11-24 1998-11-24
PCT/US1999/027828 WO2000031096A1 (en) 1998-11-24 1999-11-23 Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
BR9915965A true BR9915965A (en) 2001-08-21

Family

ID=22734926

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915965-1A BR9915965A (en) 1998-11-24 1999-11-23 Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation

Country Status (7)

Country Link
EP (1) EP1133509A1 (en)
JP (1) JP2002530421A (en)
CN (1) CN1328566A (en)
AU (1) AU1633000A (en)
BR (1) BR9915965A (en)
CA (1) CA2350066A1 (en)
WO (1) WO2000031096A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2351059A1 (en) * 1998-11-24 2000-06-15 American Home Products Corporation Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
CN103360437B (en) * 2013-04-27 2015-10-21 江苏教育学院 A kind of Thioctic Acid carbohydrate derivative and preparation method thereof and preparing the application in antitumor drug

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115745A (en) * 1994-11-07 2000-11-21 American Home Prod Acylated benzylglycosides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO2000031096A1 (en) 2000-06-02
CA2350066A1 (en) 2000-06-02
JP2002530421A (en) 2002-09-17
AU1633000A (en) 2000-06-13
CN1328566A (en) 2001-12-26
EP1133509A1 (en) 2001-09-19

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired