BR9913071A - Uso de um composto derivado de taxóide - Google Patents

Uso de um composto derivado de taxóide

Info

Publication number
BR9913071A
BR9913071A BR9913071-8A BR9913071A BR9913071A BR 9913071 A BR9913071 A BR 9913071A BR 9913071 A BR9913071 A BR 9913071A BR 9913071 A BR9913071 A BR 9913071A
Authority
BR
Brazil
Prior art keywords
taxoid
hydroxy
colon cancer
present
compound derived
Prior art date
Application number
BR9913071-8A
Other languages
English (en)
Inventor
Marie-Christine Bissery
Patricia Vrignaud
Simon Roberts
Clive Brealey
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Priority claimed from PCT/EP1999/006292 external-priority patent/WO2000010547A2/en
Publication of BR9913071A publication Critical patent/BR9913071A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

"USO DE UM COMPOSTO DERIVADO DE TAXóIDE" A presente invenção diz respeito a um novo uso de derivados de taxóide. Diz respeito mais precisamente a um processo para o tratamento de proliferação celular anormal de linhagens celulares resistentes diferentes expressando resistência a múltiplos medicamentos de P-glicoproteína. Este tipo de célula é típido de células de câncer do cólon. Os produtos da presente invenção são também usáveis para tratar o câncer do cólon de mamíferos incluindo o homem. O composto preferido é (2R,3S)-3-terc-butoxicarbonilamino-2-hidróxi-3-fenilpropionato de 4<244>-acetóxi-2<244>-benzilóxi-5ß,20-epóxi-1ß-hidróxi-7ß,10ß-dim etóxi-9-oxo-11-taxen-13<244>-ila.
BR9913071-8A 1998-08-20 1999-08-18 Uso de um composto derivado de taxóide BR9913071A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98115650A EP0982028A1 (en) 1998-08-20 1998-08-20 New use of taxoid derivatives
PCT/EP1999/006292 WO2000010547A2 (en) 1998-08-20 1999-08-18 New use of taxoid derivatives

Publications (1)

Publication Number Publication Date
BR9913071A true BR9913071A (pt) 2001-05-15

Family

ID=8232487

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9913071-8A BR9913071A (pt) 1998-08-20 1999-08-18 Uso de um composto derivado de taxóide

Country Status (5)

Country Link
EP (1) EP0982028A1 (pt)
BR (1) BR9913071A (pt)
EA (1) EA200100250A1 (pt)
ID (1) ID27769A (pt)
ZA (1) ZA200101414B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2697752B1 (fr) 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6441026B1 (en) * 1993-11-08 2002-08-27 Aventis Pharma S.A. Antitumor compositions containing taxane derivatives
US6071952A (en) * 1998-12-02 2000-06-06 Mylan Pharmaceuticals, Inc. Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2697522B1 (fr) * 1992-10-30 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
MA23823A1 (fr) * 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
FR2732968B1 (fr) * 1995-04-14 1997-05-16 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
ID27769A (id) 2001-04-26
EP0982028A1 (en) 2000-03-01
ZA200101414B (en) 2001-08-21
EA200100250A1 (ru) 2001-08-27

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Legal Events

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B08F Application fees: dismissal - article 86 of industrial property law

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B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

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