BR9911984A - Composition containing gricerol trinitrate, processes for its preparation and application - Google Patents

Composition containing gricerol trinitrate, processes for its preparation and application

Info

Publication number
BR9911984A
BR9911984A BR9911984-6A BR9911984A BR9911984A BR 9911984 A BR9911984 A BR 9911984A BR 9911984 A BR9911984 A BR 9911984A BR 9911984 A BR9911984 A BR 9911984A
Authority
BR
Brazil
Prior art keywords
preparation
active substance
application
processes
trinitrate
Prior art date
Application number
BR9911984-6A
Other languages
Portuguese (pt)
Inventor
Achim Berthold
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of BR9911984A publication Critical patent/BR9911984A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçãO CONTENDO TRINITRATO DE GLICEROL, PROCESSOS PARA SUA PREPARAçãO E SUA APLICAçãO"<D>. Um preparado para a aplicação terapêutica transdérmica de trinitrato de glicerol pela pele humana em um organismo, contendo em uma camada auto-adesiva à base de poliacrilato com uma camada reversa impermeável à substância ativa uma fração terapeuticamente eficaz da substância ativa, é caracterizado pelo fato de que - para a camada contendo substância ativa é aplicada uma massa auto-adesiva à base de poliacrilato, - a concentração de acetato de vinila na massa importa no máximo em 6 % em peso e - a concentração da substância ativa na massa importa no máximo em 25 % em peso.Invention Patent: <B> "COMPOSITION CONTAINING GLYCEROL TRINITRATE, PROCESSES FOR ITS PREPARATION AND APPLICATION" <D>. A preparation for the transdermal therapeutic application of glycerol trinitrate by human skin in an organism, containing in a self-adhesive layer based on polyacrylate with a reverse layer impermeable to the active substance a therapeutically effective fraction of the active substance, is characterized by the fact that whereas - for the layer containing the active substance, a self-adhesive polyacrylate-based mass is applied, - the concentration of vinyl acetate in the mass matters at most 6% by weight and - the concentration of the active substance in the mass matters at most 25% by weight.

BR9911984-6A 1998-07-09 1999-07-02 Composition containing gricerol trinitrate, processes for its preparation and application BR9911984A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19830648A DE19830648A1 (en) 1998-07-09 1998-07-09 Composition containing glycerol trinitrate, process for its preparation and its use
PCT/EP1999/004610 WO2000002537A1 (en) 1998-07-09 1999-07-02 Composition containing glycerol trinitrate, method for producing said composition and use of the same

Publications (1)

Publication Number Publication Date
BR9911984A true BR9911984A (en) 2001-03-27

Family

ID=7873427

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911984-6A BR9911984A (en) 1998-07-09 1999-07-02 Composition containing gricerol trinitrate, processes for its preparation and application

Country Status (15)

Country Link
EP (1) EP1094793A1 (en)
JP (1) JP2002520268A (en)
KR (1) KR20010074687A (en)
CN (1) CN1308526A (en)
AU (1) AU4781499A (en)
BR (1) BR9911984A (en)
CA (1) CA2336704A1 (en)
DE (1) DE19830648A1 (en)
HU (1) HUP0104950A3 (en)
IL (1) IL140739A0 (en)
MX (1) MXPA01000127A (en)
PL (1) PL345545A1 (en)
TR (1) TR200100020T2 (en)
WO (1) WO2000002537A1 (en)
ZA (1) ZA200100173B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002235155A1 (en) * 2000-12-05 2002-06-18 Noven Pharmaceuticals, Inc. Crystallization inhibition of drugs in transdermal drug delivery systems
JP5681883B2 (en) * 2009-03-27 2015-03-11 株式会社 メドレックス External preparation composition containing nucleic acid as active ingredient
JP5816881B2 (en) * 2014-05-21 2015-11-18 株式会社 メドレックス External preparation composition containing nucleic acid as active ingredient

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5777617A (en) * 1980-10-20 1982-05-15 Nichiban Co Ltd Plaster for cardiac disease
US4751087A (en) * 1985-04-19 1988-06-14 Riker Laboratories, Inc. Transdermal nitroglycerin delivery system
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
JPH07116032B2 (en) * 1990-04-06 1995-12-13 積水化学工業株式会社 Nitroglycerin patch
EP0518113A1 (en) * 1991-06-10 1992-12-16 Schwarz Pharma Ag Nitroglycerin-plaster and its preparation
DE856311T1 (en) * 1996-12-10 1999-02-25 Rotta Research B.V., Amsterdam Transdermal drug delivery system for the treatment of heart disease

Also Published As

Publication number Publication date
HUP0104950A3 (en) 2002-07-29
PL345545A1 (en) 2001-12-17
TR200100020T2 (en) 2001-07-23
KR20010074687A (en) 2001-08-09
HUP0104950A2 (en) 2002-06-29
EP1094793A1 (en) 2001-05-02
CA2336704A1 (en) 2000-01-20
DE19830648A1 (en) 2000-01-13
AU4781499A (en) 2000-02-01
CN1308526A (en) 2001-08-15
WO2000002537A1 (en) 2000-01-20
ZA200100173B (en) 2001-08-10
IL140739A0 (en) 2002-02-10
JP2002520268A (en) 2002-07-09
MXPA01000127A (en) 2002-06-04

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]