BR9904931A - Inhibition of amyloidoses - Google Patents

Inhibition of amyloidoses

Info

Publication number
BR9904931A
BR9904931A BR9904931-7A BR9904931A BR9904931A BR 9904931 A BR9904931 A BR 9904931A BR 9904931 A BR9904931 A BR 9904931A BR 9904931 A BR9904931 A BR 9904931A
Authority
BR
Brazil
Prior art keywords
inhibition
amyloidoses
amyloidosis
deals
ortho
Prior art date
Application number
BR9904931-7A
Other languages
Portuguese (pt)
Inventor
Sergio Teixeira Ferreira
Fernanda Guarino De Felice
Paulo Roberto Ferreira Louzada
Original Assignee
Sergio Teixeira Ferreira
Fernanda Guarino De Felice
Paulo Roberto Ferreira Louzada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sergio Teixeira Ferreira, Fernanda Guarino De Felice, Paulo Roberto Ferreira Louzada filed Critical Sergio Teixeira Ferreira
Priority to BR9904931-7A priority Critical patent/BR9904931A/en
Priority to PCT/IB2000/001687 priority patent/WO2001028546A1/en
Priority to AU11703/01A priority patent/AU1170301A/en
Publication of BR9904931A publication Critical patent/BR9904931A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A61K31/06—Phenols the aromatic ring being substituted by nitro groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Patente de Invenção "INIBIçãO DE AMILOIDOSES" A presente invenção, em seu conceito mais geral, trata da inibição de amiloidoses e de seu diagnóstico utilizando derivados dos compostos da fórmula I ou seus sais farmaceuticamente aceitáveis, onde: R¹ é selecionado dentre H, OH, C~ 1~-C~ 4~ alquil éteres; R² é selecionado dentre H, NO~ 2~, NH~ 2~; R³ é selecionado dentre H, NO~ 2~, NH~ 2~, onde, R² e R³, podem ocupar as posições orto, meta ou para.Invention Patent "INHIBITION OF AMYLOIDOSES" The present invention, in its most general concept, deals with the inhibition of amyloidosis and its diagnosis using derivatives of the compounds of formula I or their pharmaceutically acceptable salts, where: R¹ is selected from H, OH, C ~ 1 ~ -C ~ 4 ~ alkyl ethers; R² is selected from H, NO ~ 2 ~, NH ~ 2 ~; R³ is selected from H, NO ~ 2 ~, NH ~ 2 ~, where, R² and R³, can occupy the ortho, meta or para positions.

BR9904931-7A 1999-10-18 1999-10-18 Inhibition of amyloidoses BR9904931A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
BR9904931-7A BR9904931A (en) 1999-10-18 1999-10-18 Inhibition of amyloidoses
PCT/IB2000/001687 WO2001028546A1 (en) 1999-10-18 2000-10-18 Inhibition of amyloidoses by using aromatic or heteroaromatic compounds substituted by electron-withdrawing groups
AU11703/01A AU1170301A (en) 1999-10-18 2000-10-18 Inhibition of amyloidoses by using aromatic or heteroaromatic compounds substituted by electron-withdrawing groups

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR9904931-7A BR9904931A (en) 1999-10-18 1999-10-18 Inhibition of amyloidoses

Publications (1)

Publication Number Publication Date
BR9904931A true BR9904931A (en) 2001-06-12

Family

ID=4073716

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9904931-7A BR9904931A (en) 1999-10-18 1999-10-18 Inhibition of amyloidoses

Country Status (3)

Country Link
AU (1) AU1170301A (en)
BR (1) BR9904931A (en)
WO (1) WO2001028546A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1317048B1 (en) * 2000-06-23 2003-05-26 Sigma Tau Ind Farmaceuti USE OF PAMOIC ACID OR ITS DERIVATIVE, OR ANALOGUE, FOR THE PREPARATION OF A MEDICATION FOR THE TREATMENT OF DISEASES
CN101291665A (en) * 2005-10-18 2008-10-22 希格马托制药工业公司 Naphthyl derivatives as inhibitors of beta-amyloid aggregation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5488145A (en) * 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
IT1282736B1 (en) * 1996-05-21 1998-03-31 Angelini Ricerche Spa USE OF P-AMINOPHENOL DERIVATIVES TO PREPARE PHARMACEUTICAL COMPOSITIONS USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES
US6046232A (en) * 1997-10-17 2000-04-04 Centaur Pharmaceuticals, Inc. α-aryl-N-alkylnitrones and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
AU1170301A (en) 2001-04-30
WO2001028546A1 (en) 2001-04-26

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Legal Events

Date Code Title Description
B25C Requirement related to requested transfer of rights

Owner name: SERGIO TEIXEIRA FERREIRA (BR/RJ) , FERNANDA GUARIN

Free format text: A FIM DE ATENDER A TRANSFERENCIA DO TITULAR REQUERIDA NA PETICAO NO 050335/RJ DE 08/09/2003, FAVORAPRESENTAR DOCUMENTO DE CESSAO COM A ASSINATURA DA CESSIONARIA, BEM COMO AS DEVIDAS FIRMAS RECONHECIDAS DAS ASSINATURAS (CEDENTE, CESSIONARIA E TESTEMUNHA).

B25A Requested transfer of rights approved

Owner name: UNIVERSIDADE FEDERAL DO RIO DE JANEIRO (BR/RJ)

Free format text: TRANSFERIDO DE: SERGIO TEIXEIRA FERREIRA, FERNANDA GUARINO DE FELICE E PAULO ROBERTO FERREIRA LOUZADA JUNIOR.

B07A Technical examination (opinion): publication of technical examination (opinion)
B15K Others concerning applications: alteration of classification

Free format text: ALTERADO DE INT.CL: A61K 31/136; A61K 31/06; A61K 31/085; A61K 31/04; A61K 31/05; A61K 51/04; A61P25/28

Ipc: A61K 31/136 (2008.01), A61K 31/06 (2008.01), A61K

B06G Technical and formal requirements: other requirements

Free format text: A PETICAO NO 020080086001 APRESENTADA PELA REQUERENTE EM 17/06/2008 CONTEM: ESCLARECIMENTO SOBRE ATROCA DO PROCURADOR PARA ATEM AND REMER ASSESSORIA E CONSULTORIA DE PROPRIEDADE INDUSTRIAL LTDA; MANIFESTACAO SOBRE O PARECER DESFAVORAVEL; NOVA FOLHA 1 DO RELATORIO DESCRITIVO; NOVO QUADRO REIVINDICATORIO COM 28 REIVINDICACOES; E, RESUMO. O DEPOSITANTE DEVERA RESPONDER AS EXIGENCIAS FORMULADAS NESTE PARECER EM ATE 60 (SESSENTA) DIAS, A PARTIR DA DATA DE PUBLICACAO NA RPI.

B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal

Free format text: INDEFERIDO O PEDIDO COM BASE NOS ARTIGOS 8O, 13 DA LPI.

B09B Decision: refusal

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