BR9814523A - "composição farmacêutica contendo cloridrato de bupropion e um estabilizador de ácido inorgânico" - Google Patents
"composição farmacêutica contendo cloridrato de bupropion e um estabilizador de ácido inorgânico"Info
- Publication number
- BR9814523A BR9814523A BR9814523-1A BR9814523A BR9814523A BR 9814523 A BR9814523 A BR 9814523A BR 9814523 A BR9814523 A BR 9814523A BR 9814523 A BR9814523 A BR 9814523A
- Authority
- BR
- Brazil
- Prior art keywords
- bupropion hydrochloride
- pharmaceutical composition
- composition containing
- inorganic acid
- acid stabilizer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"COMPOSIçãO FARMACêUTICA CONTENDO CLORIDRATO DE BUPROPION E UM ESTABILIZADOR DE áCIDO INORGâNICO"<D>. São providenciadas formulações novas e estáveis de cloridrato de bupropion, as quais manterão pelo menos 80% da potencialidade do cloridrato de bupropion inicial depois de um ano. Métodos de inibir a degradação do cloridrato de bupropion também são providenciados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/000,673 US5968553A (en) | 1997-12-30 | 1997-12-30 | Pharmaceutical composition containing bupropion hydrochloride and an inorganic acid stabilizer |
PCT/US1998/027619 WO1999033456A1 (en) | 1997-12-30 | 1998-12-23 | Pharmaceutical compositions containing bupropion hydrochloride and an inorganic acid stabilizer |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9814523A true BR9814523A (pt) | 2000-10-17 |
Family
ID=21692550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9814523-1A BR9814523A (pt) | 1997-12-30 | 1998-12-23 | "composição farmacêutica contendo cloridrato de bupropion e um estabilizador de ácido inorgânico" |
Country Status (6)
Country | Link |
---|---|
US (1) | US5968553A (pt) |
EP (1) | EP1043984A1 (pt) |
AU (1) | AU2015399A (pt) |
BR (1) | BR9814523A (pt) |
CA (1) | CA2316985C (pt) |
WO (1) | WO1999033456A1 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6153223A (en) * | 1998-06-05 | 2000-11-28 | Watson Pharmaceuticals, Inc. | Stabilized pharmaceutical compositions |
CA2253770A1 (en) * | 1998-11-23 | 2000-05-23 | Bernard Charles Sherman | Pharmaceutical composition comprising bupropion hydrochloride |
US6238697B1 (en) * | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
US8545880B2 (en) * | 1999-02-26 | 2013-10-01 | Andrx Pharmaceuticals, Llc | Controlled release oral dosage form |
US6306436B1 (en) | 2000-04-28 | 2001-10-23 | Teva Pharmaceuticals Usa, Inc. | Stabilized, acid-free formulation for sustained release of bupropion hydrochloride |
US6333332B1 (en) * | 2000-08-25 | 2001-12-25 | Impax Laboratories, Inc. | Stabilized pharmaceutical compositions containing bupropion hydrochloride |
US20030044462A1 (en) * | 2001-08-20 | 2003-03-06 | Kali Laboratories, Inc. | Sustained release tablets containing bupropion hydrochloride |
US6893660B2 (en) * | 2002-11-21 | 2005-05-17 | Andrx Pharmaceuticals, Inc. | Stable pharmaceutical compositions without a stabilizer |
US20050096311A1 (en) * | 2003-10-30 | 2005-05-05 | Cns Response | Compositions and methods for treatment of nervous system disorders |
US8586085B2 (en) * | 2004-11-08 | 2013-11-19 | Biokey, Inc. | Methods and formulations for making pharmaceutical compositions containing bupropion |
US20060099262A1 (en) * | 2004-11-08 | 2006-05-11 | Biokey, Inc. | Methods and formulations for making controlled release oral dosage form |
KR100670798B1 (ko) | 2004-12-17 | 2007-01-17 | 한국전자통신연구원 | 데이터베이스 캐시 시스템 |
US20060204571A1 (en) * | 2005-03-12 | 2006-09-14 | Sun Pharmaceutical Industries Limited | Stable compositions of bupropion or its pharmaceutically acceptable salts |
EP1896002A4 (en) * | 2005-06-27 | 2009-11-25 | Biovail Lab Int Srl | BUPROPIONAL SALT FORMULATIONS WITH MODIFIED RELEASE |
US7674479B2 (en) * | 2006-07-25 | 2010-03-09 | Intelgenx Corp. | Sustained-release bupropion and bupropion/mecamylamine tablets |
US8703191B2 (en) * | 2006-07-25 | 2014-04-22 | Intelgenx Corp. | Controlled-release pharmaceutical tablets |
US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
US20110136815A1 (en) | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
WO2012118562A1 (en) * | 2011-03-02 | 2012-09-07 | Rhine Pharmaceuticals, Llc | Compositions and methods for treating depression, adhd and other central nervous system disorders employing novel bupropion compounds, and methods for production and use of novel bupropion compounds and formulations |
WO2014060856A1 (en) * | 2012-10-16 | 2014-04-24 | Wockhardt Limited | Pharmaceutical compositions of diclofenac or salts thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US33994A (en) * | 1861-12-24 | Improved seat for schools | ||
US3885046A (en) * | 1969-12-04 | 1975-05-20 | Burroughs Wellcome Co | Meta chloro or fluoro substituted alpha-T-butylaminopropionphenones in the treatment of depression |
BE759838A (fr) * | 1969-12-04 | 1971-06-03 | Wellcome Found | Cetones a activite biologique |
USRE33994E (en) | 1983-08-16 | 1992-07-14 | Burroughs Wellcome Co. | Pharmaceutical delivery system |
GB9217295D0 (en) * | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
US5358970A (en) * | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
GB9315856D0 (en) * | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
-
1997
- 1997-12-30 US US09/000,673 patent/US5968553A/en not_active Expired - Lifetime
-
1998
- 1998-12-23 EP EP98964939A patent/EP1043984A1/en not_active Withdrawn
- 1998-12-23 WO PCT/US1998/027619 patent/WO1999033456A1/en not_active Application Discontinuation
- 1998-12-23 AU AU20153/99A patent/AU2015399A/en not_active Abandoned
- 1998-12-23 BR BR9814523-1A patent/BR9814523A/pt not_active IP Right Cessation
- 1998-12-23 CA CA002316985A patent/CA2316985C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2316985A1 (en) | 1999-07-08 |
US5968553A (en) | 1999-10-19 |
EP1043984A1 (en) | 2000-10-18 |
AU2015399A (en) | 1999-07-19 |
WO1999033456A1 (en) | 1999-07-08 |
CA2316985C (en) | 2007-06-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFARENTE A 7O E 8O ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007. |