BR9814394A - Thiazole, isothiazole and thiadiazole derivatives that have microbicidal and plant immunization activities - Google Patents

Thiazole, isothiazole and thiadiazole derivatives that have microbicidal and plant immunization activities

Info

Publication number
BR9814394A
BR9814394A BR9814394-8A BR9814394A BR9814394A BR 9814394 A BR9814394 A BR 9814394A BR 9814394 A BR9814394 A BR 9814394A BR 9814394 A BR9814394 A BR 9814394A
Authority
BR
Brazil
Prior art keywords
microbicidal
isothiazole
thiazole
thiadiazole derivatives
plant immunization
Prior art date
Application number
BR9814394-8A
Other languages
Portuguese (pt)
Inventor
Philippe Chemla
Thomas Maetzke
Peter Ertl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9814394A publication Critical patent/BR9814394A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/781,3-Thiazoles; Hydrogenated 1,3-thiazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/82Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/061,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS DE TIAZOL, ISOTIAZOL E TIADIAZOL QUE APRESENTAM ATIVIDADES MICROBICIDAS E DE IMUNIZAçãO DE PLANTAS"<D>. A invenção refere-se a compostos de fórmula I e a processo para proteção e imunização de plantas contra ataque por microorganismos através de aplicação dos compostos de fórmula I onde a) X é CR~ 4~ e Y é N; ou b) X é N e Y é CR~ 5~; ou c) X e Y são N; e onde Z é um grupo C~ 1~ ao qual estão ligados 1-3 átomos de halogênio ou 1-3 hetero átomos não-substituídos ou substituídos selecionados do grupo O, S e N: Z é CN, CO-A, CS-A ou CH(OR~ 10~)~ 2~; A é hidrogênio, halogênio OR~ 6~, SR~ 7~, N(R~ 8~)R~ 9~, ON(R~ 11~)R~ 12~ ou N(R~ 13~)OR~ 14~' e onde R~ 1~-R~ 14~ tem os significados dados na descrição.Invention Patent: <B> "THIAZOL, ISOTIAZOL AND THYADIAZOL DERIVATIVES THAT PRESENT MICROBICID AND PLANT IMMUNIZATION ACTIVITIES" <D>. The invention relates to compounds of formula I and the process for protecting and immunizing plants against attack by microorganisms through the application of compounds of formula I where a) X is CR ~ 4 ~ and Y is N; or b) X is N and Y is CR ~ 5 ~; or c) X and Y are N; and where Z is a C ~ 1 ~ group to which 1-3 halogen atoms or 1-3 unsubstituted or substituted hetero atoms selected from the group O, S and N are attached: Z is CN, CO-A, CS- A or CH (OR ~ 10 ~) ~ 2 ~; A is hydrogen, halogen OR ~ 6 ~, SR ~ 7 ~, N (R ~ 8 ~) R ~ 9 ~, ON (R ~ 11 ~) R ~ 12 ~ or N (R ~ 13 ~) OR ~ 14 ~ 'and where R ~ 1 ~ -R ~ 14 ~ has the meanings given in the description.

BR9814394-8A 1997-12-22 1998-12-18 Thiazole, isothiazole and thiadiazole derivatives that have microbicidal and plant immunization activities BR9814394A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726989.8A GB9726989D0 (en) 1997-12-22 1997-12-22 Organic compounds
PCT/EP1998/008335 WO1999032464A1 (en) 1997-12-22 1998-12-18 Thiazole-, isothiazole- and thiadiazole-derivatives having microbicidal and plant immunizing activities

Publications (1)

Publication Number Publication Date
BR9814394A true BR9814394A (en) 2000-10-10

Family

ID=10823994

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814394-8A BR9814394A (en) 1997-12-22 1998-12-18 Thiazole, isothiazole and thiadiazole derivatives that have microbicidal and plant immunization activities

Country Status (15)

Country Link
EP (1) EP1042306A1 (en)
JP (1) JP2001526277A (en)
CN (1) CN1282324A (en)
AR (1) AR017438A1 (en)
AU (1) AU2054699A (en)
BR (1) BR9814394A (en)
CA (1) CA2309973A1 (en)
GB (1) GB9726989D0 (en)
GT (1) GT199800193A (en)
HU (1) HUP0100619A3 (en)
IL (1) IL136589A0 (en)
PL (1) PL341290A1 (en)
TR (1) TR200001740T2 (en)
WO (1) WO1999032464A1 (en)
ZA (1) ZA9811706B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
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US6310052B1 (en) 1996-06-04 2001-10-30 Queen's University At Kingston Nitrate esters and their use for neurological conditions
CA2408686A1 (en) * 2000-05-15 2002-11-12 Basf Aktiengesellschaft 3-arylisothiazoles and their use as herbicides
DE10029077A1 (en) * 2000-06-13 2001-12-20 Bayer Ag New heterocyclic-substituted thiazole derivatives, useful as total or selective herbicides, insecticides, acaricides, nematocides, ectoparasiticides or antifouling agents
BR0208956A (en) 2001-04-16 2004-07-13 Tanabe Seiyaku Co High Conductance Calcium Activated K Channel Opener
AU2002314744A1 (en) 2001-04-17 2002-10-28 Sepracor, Inc. Thiazole and other heterocyclic ligands and use thereof
GB0712653D0 (en) 2007-06-28 2007-08-08 Syngenta Ltd Novel herbicides
GB0717082D0 (en) 2007-09-03 2007-10-10 Syngenta Ltd Novel herbicides
MX2012006349A (en) * 2009-12-07 2012-10-03 Cardioxyl Pharmaceuticals Inc N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives.
US9018411B2 (en) 2009-12-07 2015-04-28 Cardioxyl Pharmaceuticals, Inc. Bis-acylated hydroxylamine derivatives
BR112012030208A2 (en) * 2010-05-27 2015-09-29 Bayer Intelectual Property Gmbh heterocyclic alkanol derivatives as fungicides
JP5872548B2 (en) * 2010-05-27 2016-03-01 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH Heterocyclic alkanol derivatives as fungicides
EP2576528A1 (en) * 2010-05-27 2013-04-10 Bayer CropScience AG Heterocyclic alkanol derivatives as fungicides
EP2508511A1 (en) * 2011-04-07 2012-10-10 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
CN102417505B (en) * 2011-08-29 2014-07-09 南开大学 Tetrazole compounds containing methyl-1,2,3-thiadiazole as well as preparation methods and application thereof
CN108752287A (en) * 2018-05-21 2018-11-06 南开大学 The preparation method and purposes of heterocycle tertiary alcohol derivative
CN108912108B (en) * 2018-06-27 2021-09-03 中国科学院上海有机化学研究所 Trifluoromethyl compound, preparation method thereof and application thereof in pesticide
CN113214241A (en) * 2021-04-29 2021-08-06 华东理工大学 Compound for detecting sclerotinia sclerotiorum of cruciferous vegetables and application thereof

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DE1953861C2 (en) * 1969-10-25 1982-12-23 Fujisawa Pharmaceutical Co., Ltd., Osaka 7-tetrazolylacetamido-3-thiomethyl-3-cephem-4-carboxylic acids
BE793037A (en) * 1971-12-23 1973-06-20 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF 7-ACYLAMINO-3-SUBSTITUE-3-CEPHEM-4-CARBOXYLIC ACID DERIVATIVES AND NEW PRODUCTS THUS OBTAINED
EP0213079A3 (en) * 1985-08-23 1987-08-05 Ciba-Geigy Ag Thienylalkyl esters from alpha-imidazolinon nicotine and benzoe acids
US5135927A (en) * 1987-01-30 1992-08-04 Ciba-Geigy Corporation Microbicidal composition
CA2014880A1 (en) * 1989-04-27 1990-10-27 Indu Sawhney Thiazole derivatives
JP3726306B2 (en) * 1994-04-27 2005-12-14 日産化学工業株式会社 Pyrazolecarboxylic acid derivatives and plant disease control agents
WO1996017840A1 (en) * 1994-12-06 1996-06-13 Agrevo Uk Limited Heterocyclyl substituted hydroxyacetamide derivatives as fongicides
MY113237A (en) * 1995-03-31 2001-12-31 Nihon Nohyaku Co Ltd An agricultural and horticultural disease controller and a method for controlling the diseases
DE19545638A1 (en) * 1995-12-07 1997-06-12 Bayer Ag Use of 1,2,3-thiadiazolecarboxylic acid (thio) esters to control pests
CN1072657C (en) * 1996-09-30 2001-10-10 日本农药株式会社 1,2,3-thiadiazole derivs. and salts thereof, disease agent for agricultural and horticultural use and method for use thereof

Also Published As

Publication number Publication date
GT199800193A (en) 2000-05-25
PL341290A1 (en) 2001-04-09
WO1999032464A1 (en) 1999-07-01
AR017438A1 (en) 2001-09-05
CN1282324A (en) 2001-01-31
IL136589A0 (en) 2001-06-14
ZA9811706B (en) 1999-06-22
CA2309973A1 (en) 1999-07-01
HUP0100619A3 (en) 2002-03-28
HUP0100619A2 (en) 2001-06-28
EP1042306A1 (en) 2000-10-11
TR200001740T2 (en) 2000-11-21
GB9726989D0 (en) 1998-02-18
JP2001526277A (en) 2001-12-18
AU2054699A (en) 1999-07-12

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FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]