BR9808863A - Composições antiestrogênicas peptìdicas e métodos para tratar câncer de mama - Google Patents
Composições antiestrogênicas peptìdicas e métodos para tratar câncer de mamaInfo
- Publication number
- BR9808863A BR9808863A BR9808863-7A BR9808863A BR9808863A BR 9808863 A BR9808863 A BR 9808863A BR 9808863 A BR9808863 A BR 9808863A BR 9808863 A BR9808863 A BR 9808863A
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- methods
- peptide
- breast cancer
- antiestrogenic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- High Energy & Nuclear Physics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMPOSIçõES ANTIESTROGêNICAS PEPTìDICAS E MéTODOS PARA TRATAR CâNCER DE MAMA" A presente invenção refere-se a métodos e composições que compreendem peptídios nativos, mutagenizados especificamente no sítio e sintéticos compreendendo uma porção do receptor de estrogênio humano, ou co-ativador de receptor de estrogênio, e composições de ácido nucléico que codificam estas composições de polipeptídios. São também descritos métodos para sintetizar derivados de peptídio de fosfotirosila e maloniltirosila e seu uso como composições antiestrogênicas no tratamento de cânceres de mama, a preparação de composições farmacêuticas, kits para diagnósticos e o desenvolvimento de ensaios relacionados para uso em terapias antitumor.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4354597P | 1997-04-14 | 1997-04-14 | |
PCT/US1998/007711 WO1998046250A1 (en) | 1997-04-14 | 1998-04-14 | Peptide antiestrogen compositions and methods for treating breast cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9808863A true BR9808863A (pt) | 2001-09-18 |
Family
ID=21927706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9808863-7A BR9808863A (pt) | 1997-04-14 | 1998-04-14 | Composições antiestrogênicas peptìdicas e métodos para tratar câncer de mama |
Country Status (5)
Country | Link |
---|---|
US (1) | US6306832B1 (pt) |
EP (1) | EP1005357A1 (pt) |
BR (1) | BR9808863A (pt) |
CA (1) | CA2286877A1 (pt) |
WO (1) | WO1998046250A1 (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2786397B1 (fr) * | 1998-11-30 | 2003-01-10 | Synt Em | Vecteurs peptidiques de substances a travers la barriere hematoencephalique pour etre utilises dans le diagnostic ou la therapie d'une affection du snc |
FR2786398B1 (fr) * | 1998-11-30 | 2002-12-27 | Synt Em | Composition pharmaceutique anti-cancereuse et anti-chimioresistance comprenant un agent anticancereux et au moins un peptide |
MXPA02009019A (es) | 2000-03-15 | 2003-02-12 | Du Pont Pharm Co | Farmacos antineoplasticos de objetivo, que se desdoblan por la peptidasa y su uso terapeutico. |
US6818741B2 (en) * | 2000-06-01 | 2004-11-16 | Clf Medical Technology Acceleration Program, Inc. | Alpha-fetoprotein peptides and uses therof |
US7132400B2 (en) | 2001-06-02 | 2006-11-07 | Clf Medical Technology Acceleration Program, Inc. | Alpha-fetoprotein peptides and uses thereof |
US7943577B2 (en) * | 2001-11-20 | 2011-05-17 | Albany Medical College | Alpha-fetoprotein peptides and uses thereof |
AU2002363944A1 (en) * | 2001-11-20 | 2003-06-10 | Clf Medical Technology Acceleration Program, Inc. | Alpha-fetoprotein peptides and uses for imaging |
WO2003044040A2 (en) | 2001-11-20 | 2003-05-30 | Clf Medical Technology Acceleration Program, Inc. | Alpha-fetoprotein peptides and uses thereof |
US7385027B2 (en) * | 2003-01-07 | 2008-06-10 | University Of Kentucky Research Foundation | Membrane-permeable peptide capable of calpain inhibition |
US20050095241A1 (en) * | 2003-08-26 | 2005-05-05 | Vadlamudi Ratna K. | Estrogen receptor modulators and uses thereof |
US20050255097A1 (en) * | 2004-01-26 | 2005-11-17 | Paul Reid | Modified venom and venom components as anti-retroviral agents |
US20060088843A1 (en) * | 2004-10-25 | 2006-04-27 | Reid Paul F | Modified venom and venom components as anti-retroviral agents |
US7964701B2 (en) | 2006-02-24 | 2011-06-21 | Albany Medical College | Alpha-fetoprotein peptides |
US7598342B2 (en) * | 2006-02-24 | 2009-10-06 | Albany Medical College | Alpha-fetoprotein peptides and uses thereof |
US20070225213A1 (en) * | 2006-03-23 | 2007-09-27 | Kosak Matthew K | Nucleic acid carriers for delivery of therapeutic agents |
WO2008039482A2 (en) * | 2006-09-26 | 2008-04-03 | The Regents Of The University Of California | Methods and compositions for cancer prevention and treatment |
US9517240B2 (en) | 2006-09-26 | 2016-12-13 | The Regents Of The University Of California | Methods and compositions for cancer prevention and treatment |
US20100189776A1 (en) * | 2007-03-16 | 2010-07-29 | Cancer Research Technology Ltd | Anti-androgen peptides and uses thereof in cancer therapy |
US9249189B2 (en) | 2010-01-18 | 2016-02-02 | Albany Medical College | Alpha-fetoprotein “ring and tail” peptides |
GB2496135B (en) * | 2011-11-01 | 2015-03-18 | Valirx Plc | Inhibitors of the interaction between a Src family kinase and an androgen receptor or estradiol receptor for treatment of endometriosis |
GB2513615A (en) | 2013-05-01 | 2014-11-05 | Cancer Rec Tech Ltd | Medical use |
US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
TW202016144A (zh) | 2018-06-21 | 2020-05-01 | 日商第一三共股份有限公司 | 包括cd3抗原結合片段之組成物及其用途 |
EP3938400A4 (en) | 2019-03-11 | 2022-11-23 | Memorial Sloan Kettering Cancer Center | CD22 ANTIBODIES AND METHODS OF USE THEREOF |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4720455A (en) * | 1985-09-06 | 1988-01-19 | Pitman-Moore, Inc. | Progesterone assay method for mammals and monoclonal antibody therefor |
US5728534A (en) * | 1996-07-19 | 1998-03-17 | New England Medical Center Hospitals, Inc. | Methods for identifying cardiovascular therapeutic agents |
-
1998
- 1998-04-14 EP EP98918327A patent/EP1005357A1/en not_active Withdrawn
- 1998-04-14 CA CA002286877A patent/CA2286877A1/en not_active Abandoned
- 1998-04-14 WO PCT/US1998/007711 patent/WO1998046250A1/en not_active Application Discontinuation
- 1998-04-14 BR BR9808863-7A patent/BR9808863A/pt not_active IP Right Cessation
-
1999
- 1999-10-14 US US09/419,826 patent/US6306832B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU7127398A (en) | 1998-11-11 |
AU737627B2 (en) | 2001-08-23 |
EP1005357A1 (en) | 2000-06-07 |
WO1998046250A1 (en) | 1998-10-22 |
US6306832B1 (en) | 2001-10-23 |
CA2286877A1 (en) | 1998-10-22 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A, 8A E 9A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1889 DE 20/03/2007. |