BR9106392A - ANTI-ICAM-1 ANTIBODIES GRAFTED-HUMANIZED CDR, METHODS OF PREPARATION AND USE OF THE SAME - Google Patents

ANTI-ICAM-1 ANTIBODIES GRAFTED-HUMANIZED CDR, METHODS OF PREPARATION AND USE OF THE SAME

Info

Publication number
BR9106392A
BR9106392A BR919106392A BR9106392A BR9106392A BR 9106392 A BR9106392 A BR 9106392A BR 919106392 A BR919106392 A BR 919106392A BR 9106392 A BR9106392 A BR 9106392A BR 9106392 A BR9106392 A BR 9106392A
Authority
BR
Brazil
Prior art keywords
icam
preparation
methods
same
humanized cdr
Prior art date
Application number
BR919106392A
Other languages
Portuguese (pt)
Inventor
John Robert Adair
Dijeet Singh Athwal
Robert A Rothleim
Original Assignee
Celltech Ltd
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech Ltd, Boehringer Ingelheim Pharma filed Critical Celltech Ltd
Publication of BR9106392A publication Critical patent/BR9106392A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
BR919106392A 1990-04-27 1991-04-29 ANTI-ICAM-1 ANTIBODIES GRAFTED-HUMANIZED CDR, METHODS OF PREPARATION AND USE OF THE SAME BR9106392A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909009549A GB9009549D0 (en) 1990-04-27 1990-04-27 Recombinant antibody and method
PCT/US1991/002942 WO1991016927A1 (en) 1990-04-27 1991-04-29 Humanized cdr-grafted anti-icam-1 antibodies, methods of preparation and usage thereof

Publications (1)

Publication Number Publication Date
BR9106392A true BR9106392A (en) 1993-04-27

Family

ID=10675134

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919106392A BR9106392A (en) 1990-04-27 1991-04-29 ANTI-ICAM-1 ANTIBODIES GRAFTED-HUMANIZED CDR, METHODS OF PREPARATION AND USE OF THE SAME

Country Status (8)

Country Link
EP (1) EP0528951A4 (en)
JP (1) JPH06500229A (en)
AU (1) AU7900191A (en)
BR (1) BR9106392A (en)
CA (1) CA2081478A1 (en)
GB (1) GB9009549D0 (en)
HU (2) HUT62652A (en)
WO (1) WO1991016927A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
GB9009548D0 (en) * 1990-04-27 1990-06-20 Celltech Ltd Chimeric antibody and method
EP0459577A3 (en) * 1990-06-01 1992-08-05 Merck & Co. Inc. Microbially expressed portions of a monoclonal antibody block rhinovirus attachment to cell receptors
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5223396A (en) * 1991-05-03 1993-06-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for detecting organ transplant rejection
CA2120500A1 (en) * 1991-10-01 1993-04-15 Mitsuaki Isobe Preventing allograft rejection with antibodies to adhesion molecules
US5635177A (en) 1992-01-22 1997-06-03 Genentech, Inc. Protein tyrosine kinase agonist antibodies
MX9305070A (en) * 1992-08-21 1994-04-29 Genentech Inc PHARMACEUTICAL COMPOSITION CONTAINING AN LFA-1 ANTAGONIST FOR THE TREATMENT OF DISORDERS OR DISORDERS MEDIATED BY LFA-1
WO1994007921A1 (en) * 1992-09-25 1994-04-14 Commonwealth Scientific And Industrial Research Organisation Target binding polypeptide
US5484892A (en) * 1993-05-21 1996-01-16 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
US5695760A (en) * 1995-04-24 1997-12-09 Boehringer Inglehiem Pharmaceuticals, Inc. Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
US6037454A (en) * 1996-11-27 2000-03-14 Genentech, Inc. Humanized anti-CD11a antibodies
US20030035798A1 (en) * 2000-08-16 2003-02-20 Fang Fang Humanized antibodies
US6670321B1 (en) 1998-12-30 2003-12-30 The Children's Medical Center Corporation Prevention and treatment for retinal ischemia and edema
DE60042735D1 (en) 1999-03-19 2009-09-24 Genentech Inc TREATMENT OF LFA-1 ASSOCIATED DISEASES BY INCREASED DOSES OF LFA-1 ANTAGONIST
US6582698B1 (en) 1999-03-19 2003-06-24 Genentech, Inc. Treatment method
CN101912610A (en) 1999-06-24 2010-12-15 约翰·霍普金斯大学 Compositions and methods for preventing transepithelial transmission of hiv
AU4884001A (en) 2000-04-21 2001-11-07 Fuso Pharmaceutical Ind Novel collectins
NZ535425A (en) * 2002-03-13 2008-05-30 Biogen Idec Inc Anti-alphavbeta6 antibodies
CA2568570A1 (en) 2004-06-09 2005-12-29 Genentech, Inc. Method of treating granuloma annulare or sarcoid
CN102875681A (en) 2005-07-08 2013-01-16 拜奥根Idec马萨诸塞公司 Anti-alpha v beta 6 antibodies and uses thereof
EP2729497B1 (en) * 2011-07-05 2016-08-17 Dinona Inc. An antibody inducing antigen-specific t cell tolerance and use thereof
US10035860B2 (en) 2013-03-15 2018-07-31 Biogen Ma Inc. Anti-alpha V beta 6 antibodies and uses thereof
US10035859B2 (en) 2013-03-15 2018-07-31 Biogen Ma Inc. Anti-alpha V beta 6 antibodies and uses thereof
KR102063341B1 (en) * 2018-12-31 2020-01-07 다이노나(주) Antibody specifically binding to ICAM-1 and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8720833D0 (en) * 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
EP0314863B1 (en) * 1987-11-02 1994-12-07 Baylor College Of Medicine Use of ICAM-1 or its functional derivatives for the treatment of non-specific inflammation

Also Published As

Publication number Publication date
CA2081478A1 (en) 1991-10-28
HU9203371D0 (en) 1993-01-28
HUT62652A (en) 1993-05-28
WO1991016927A1 (en) 1991-11-14
AU7900191A (en) 1991-11-27
JPH06500229A (en) 1994-01-13
EP0528951A1 (en) 1993-03-03
EP0528951A4 (en) 1993-05-26
GB9009549D0 (en) 1990-06-20

Similar Documents

Publication Publication Date Title
BR9106392A (en) ANTI-ICAM-1 ANTIBODIES GRAFTED-HUMANIZED CDR, METHODS OF PREPARATION AND USE OF THE SAME
MX9204301A (en) ACILMERCAPTOALCANOILDIPEPTIDOS, METHODS OF PREPARATION AND ITS THERAPEUTIC USE.
MX24568A (en) 3-ARILCARBONIL-1H-INDOLES AND PROCEDURE FOR ITS PREPARATION.
NO905438D0 (en) VIRUS AGENT.
MX26267A (en) AMINOBENZODIACEPINAS AND PROCEDURE FOR ITS PREPARATION.
FR2625743B1 (en) ISOQUINOLEIN DERIVATIVES, THEIR PREPARATION AND THEIR USE
NO911122D0 (en) PROCEDURE FOR THE PREPARATION OF ANTIHYPERCOLESTEROLEMIC AGENTS.
NO910209L (en) PROCEDURE FOR THE PREPARATION OF RECOMBINANT HUMAN ANTI-CD18 ANTIBODIES.
AU7198291A (en) Human monoclonal antibodies against rabies viruses, the production and the use thereof
FI954491A (en) Heterocycles containing imidine derivatives, their preparation and use
FR2667317B1 (en) 2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
NO870476D0 (en) PROCEDURE FOR THE PREPARATION OF CROSS PROTECTIVE HUMAN MONOCLONAL ANTIBODY PREPARATIONS.
FI101382B1 (en) Dihydroxypropylsulfoethylcelluloses, preparation and use thereof
ITRM910518A0 (en) NEUROMUSCULAR BLOCKING AGENTS AND PREPARATION PROCEDURE
DE69007372D1 (en) Aroma-releasing system and its preparation.
NO912486D0 (en) PROCEDURE FOR THE PREPARATION OF THE CATALYST NETWORK AND USE OF IT.
FI961977A0 (en) N-substituted azabicycloalkane derivatives, their preparation and use
IT8821300A0 (en) PROCEDURE FOR THE PREPARATION OF MORNIFLUMATO AND SIMILARES.
FI895893A0 (en) MODIFIED VISCOSFIBRES AND FREQUENCIES FOR FRAMSTAELLNING.
ITMI912290A0 (en) MIXTURES OF N-ALKYLPHTHALIMIDES, THEIR PREPARATION AND THEIR USE
NO905543D0 (en) PROCEDURE FOR THE PREPARATION AND USE OF AMINOPYRIDINYLMETHANOLS AND AMINOMETHYLPYRIDINAMINES.
FR2677477B1 (en) NEW OXAZOLE DERIVATIVES, THEIR PREPARATION, THEIR USE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
MX18585A (en) PIRROL COMPOUNDS AND THEIR USE.
ITRM910661A0 (en) DYEING AUXILIARIES, THEIR PREPARATION AND THEIR USE
MX24596A (en) DERIVATIVE OF 1-PIRIDYLIMIDAZOLE AND PROCEDURE FOR ITS PREPARATION.

Legal Events

Date Code Title Description
FD3 Appl. lapsed due to non-payment of renewal fee
B15K Others concerning applications: alteration of classification

Ipc: C07K 16/28 (2006.01), A61K 38/00 (2006.0