BR112022025789A2 - Ensaio para avaliar a presença, ausência ou desenvolvimento de câncer, método de tratamento ou prevenção de câncer, método para monitorar o estado de câncer, arranjos e processo para fazer o arranjo - Google Patents

Ensaio para avaliar a presença, ausência ou desenvolvimento de câncer, método de tratamento ou prevenção de câncer, método para monitorar o estado de câncer, arranjos e processo para fazer o arranjo

Info

Publication number
BR112022025789A2
BR112022025789A2 BR112022025789A BR112022025789A BR112022025789A2 BR 112022025789 A2 BR112022025789 A2 BR 112022025789A2 BR 112022025789 A BR112022025789 A BR 112022025789A BR 112022025789 A BR112022025789 A BR 112022025789A BR 112022025789 A2 BR112022025789 A2 BR 112022025789A2
Authority
BR
Brazil
Prior art keywords
cancer
absence
development
assessing
arrangements
Prior art date
Application number
BR112022025789A
Other languages
English (en)
Portuguese (pt)
Inventor
Widschwendter Martin
Barrett James
Jones Allison
Evans Iona
Original Assignee
Ucl Business Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2009224.3A external-priority patent/GB202009224D0/en
Priority claimed from GBGB2107412.5A external-priority patent/GB202107412D0/en
Application filed by Ucl Business Ltd filed Critical Ucl Business Ltd
Publication of BR112022025789A2 publication Critical patent/BR112022025789A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/165Mathematical modelling, e.g. logarithm, ratio
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR112022025789A 2020-06-17 2021-06-17 Ensaio para avaliar a presença, ausência ou desenvolvimento de câncer, método de tratamento ou prevenção de câncer, método para monitorar o estado de câncer, arranjos e processo para fazer o arranjo BR112022025789A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2009224.3A GB202009224D0 (en) 2020-06-17 2020-06-17 Methods for detecting and predicting cancer and/or cin3
GBGB2107412.5A GB202107412D0 (en) 2021-05-25 2021-05-25 Methods for detecting and predicting cancer and/or CIN3
PCT/GB2021/051536 WO2021255459A1 (en) 2020-06-17 2021-06-17 Methods for detecting and predicting cancer and/or cin3

Publications (1)

Publication Number Publication Date
BR112022025789A2 true BR112022025789A2 (pt) 2023-01-10

Family

ID=76730905

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022025789A BR112022025789A2 (pt) 2020-06-17 2021-06-17 Ensaio para avaliar a presença, ausência ou desenvolvimento de câncer, método de tratamento ou prevenção de câncer, método para monitorar o estado de câncer, arranjos e processo para fazer o arranjo

Country Status (10)

Country Link
US (1) US20240191302A1 (https=)
EP (1) EP4168587A1 (https=)
JP (1) JP2023530983A (https=)
KR (1) KR20230024344A (https=)
AU (1) AU2021291133A1 (https=)
BR (1) BR112022025789A2 (https=)
CA (1) CA3186997A1 (https=)
IL (1) IL299142A (https=)
MX (1) MX2022016100A (https=)
WO (1) WO2021255459A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202315787D0 (en) * 2023-10-16 2023-11-29 Sola Diagnostics Gmbh Method
GB202401477D0 (en) * 2024-02-05 2024-03-20 Sola Diagnostics Gmbh Method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013033627A2 (en) * 2011-09-01 2013-03-07 The Regents Of The University Of California Diagnosis and treatment of arthritis using epigenetics
WO2016041010A1 (en) * 2014-09-15 2016-03-24 Garvan Institute Of Medical Research Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor
US9984201B2 (en) * 2015-01-18 2018-05-29 Youhealth Biotech, Limited Method and system for determining cancer status
JP7299158B2 (ja) * 2017-03-10 2023-06-27 セルフ-スクリーン ベー.フェー. Hpv誘発浸潤がん、非hpv誘発婦人科がん及び肛門性器がん、並びにその高度前駆病変を検出するためのメチル化分類子
US12480164B2 (en) * 2018-12-04 2025-11-25 EpiMedTechGlobal (EMTG) DNA methylation biomarkers for early detection of cervical cancer

Also Published As

Publication number Publication date
MX2022016100A (es) 2023-04-20
CA3186997A1 (en) 2021-12-23
WO2021255459A1 (en) 2021-12-23
JP2023530983A (ja) 2023-07-20
AU2021291133A1 (en) 2023-02-02
KR20230024344A (ko) 2023-02-20
EP4168587A1 (en) 2023-04-26
US20240191302A1 (en) 2024-06-13
IL299142A (en) 2023-02-01

Similar Documents

Publication Publication Date Title
Marabita et al. Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship
Murphy et al. Cannabinoid exposure and altered DNA methylation in rat and human sperm
Rossi et al. The number of excised lymph nodes is associated with survival of melanoma patients with lymph node metastasis
Leter et al. Exposure to perfluoroalkyl substances and sperm DNA global methylation in Arctic and European populations
Sen et al. Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren
Kalf et al. Variations in predicted risks in personal genome testing for common complex diseases
BRPI0515407A (pt) aparelho portátil e método para análise de uma carga de alimentação de refinaria ou de um produto de um processo de refinaria
BR112022025789A2 (pt) Ensaio para avaliar a presença, ausência ou desenvolvimento de câncer, método de tratamento ou prevenção de câncer, método para monitorar o estado de câncer, arranjos e processo para fazer o arranjo
Gaidatzis et al. DNA sequence explains seemingly disordered methylation levels in partially methylated domains of Mammalian genomes
BRPI0515276A (pt) processo para avaliação de uma matéria de refinaria
Guo et al. Multi-generational impacts of arsenic exposure on genome-wide DNA methylation and the implications for arsenic-induced skin lesions
Lawrence-Wood et al. Re-experiencing phenomena following a disaster: The long-term predictive role of intrusion symptoms in the development of post-trauma depression and anxiety
Samama Which test to use to measure the anticoagulant effect of rivaroxaban: the anti-factor Xa assay
Lee et al. MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice
BR112022007996A2 (pt) Métodos para o tratamento e uso de biomarcadores para predizer a sensibilidade clínica à 2-(4-clorofenil)-n-((2-(2,6-dioxopiperidin-3-il)-1-oxoisoindolin-5-il)metil)-2,2-difluoroacetamida
Keller et al. DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia
Herman et al. CHST11 gene expression and DNA methylation in breast cancer
BR112022019266A2 (pt) Método para detectar analitos de abundância variável
NO20071916L (no) Fremgangsmate for evaluering av et raffineriramateriale.
Kelsey et al. Serum dioxin and DNA methylation in the sperm of operation ranch hand veterans exposed to Agent Orange
Atiomo et al. Proteomic biomarkers for the diagnosis and risk stratification of polycystic ovary syndrome: a systematic review
Misteli et al. Genome instability in progeria: when repair gets old
Quaid et al. Firefighting, per‐and polyfluoroalkyl substances, and DNA methylation of genes associated with prostate cancer risk
BR112022025848A2 (pt) Ensaio para avaliar a presença, ausência ou desenvolvimento de neoplasia intraepitelial cervical, método de tratamento ou prevenção de nic3 e/ou câncer cervical, método para monitorar o estado nic3 e/ou câncer, arranjo, arranjo hibridizado e processo para fazer o arranjo hibridizado
Waugh et al. Transcriptional pathways altered in response to vibration in a model of hand-arm vibration syndrome