BR112022019234A2 - Método para tratamento de transtornos neurológicos usando treinamento de via sináp-tica - Google Patents
Método para tratamento de transtornos neurológicos usando treinamento de via sináp-ticaInfo
- Publication number
- BR112022019234A2 BR112022019234A2 BR112022019234A BR112022019234A BR112022019234A2 BR 112022019234 A2 BR112022019234 A2 BR 112022019234A2 BR 112022019234 A BR112022019234 A BR 112022019234A BR 112022019234 A BR112022019234 A BR 112022019234A BR 112022019234 A2 BR112022019234 A2 BR 112022019234A2
- Authority
- BR
- Brazil
- Prior art keywords
- brain
- synaptic
- synaptic pathway
- pathway
- training
- Prior art date
Links
- 230000037361 pathway Effects 0.000 title abstract 7
- 230000000946 synaptic effect Effects 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 208000012902 Nervous system disease Diseases 0.000 title abstract 2
- 208000025966 Neurological disease Diseases 0.000 title abstract 2
- 210000004556 brain Anatomy 0.000 abstract 4
- 230000002349 favourable effect Effects 0.000 abstract 2
- 208000028173 post-traumatic stress disease Diseases 0.000 abstract 2
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 abstract 1
- 206010026749 Mania Diseases 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000001149 cognitive effect Effects 0.000 abstract 1
- 229960003299 ketamine Drugs 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000001953 sensory effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Social Psychology (AREA)
- Developmental Disabilities (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
MÉTODO PARA TRATAMENTO DE TRANSTORNOS NEUROLÓGICOS USANDO TREINAMENTO DE VIA SINÁPTICA. São divulgados métodos de tratamento de depressão, mania, transtorno de estresse pós-traumático (PTSD) e várias outras condições neurológicas usando o treinamento das vias sinápticas. Os métodos de treinamento da via sináptica incluem, geralmente, alcançar um resultado de tratamento favorável pela ativação de uma via sináptica usando um agente farmacológico, como o tratamento de sintomas refratários de depressão com cetamina, seguido pela potencialização do resultado favorável pela estimulação repetida da via ativada. A estimulação de uma via sináptica pode ser alcançada por meios intrínsecos, como o desempenho de exercícios cognitivos, ou meios extrínsecos, como a entrega de um estímulo sensorial ao paciente, colocando uma diferença de voltagem potencial no cérebro ou em uma região do cérebro, ou colocando o cérebro ou uma região do cérebro em um campo magnético.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/827,546 US20200222656A1 (en) | 2016-10-18 | 2020-03-23 | Method for treatment of depression using synaptic pathway training |
| PCT/US2021/022517 WO2021194796A1 (en) | 2020-03-23 | 2021-03-16 | Method for treatment of neurological disorders using synaptic pathway training |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022019234A2 true BR112022019234A2 (pt) | 2022-11-08 |
Family
ID=77890584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022019234A BR112022019234A2 (pt) | 2020-03-23 | 2021-03-16 | Método para tratamento de transtornos neurológicos usando treinamento de via sináp-tica |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP4126199A4 (pt) |
| BR (1) | BR112022019234A2 (pt) |
| CA (1) | CA3172981A1 (pt) |
| IL (1) | IL296693A (pt) |
| MX (1) | MX2022011862A (pt) |
| WO (1) | WO2021194796A1 (pt) |
| ZA (1) | ZA202210356B (pt) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9064036B2 (en) * | 2008-04-24 | 2015-06-23 | The Invention Science Fund I, Llc | Methods and systems for monitoring bioactive agent use |
| WO2016004396A1 (en) * | 2014-07-02 | 2016-01-07 | Christopher Decharms | Technologies for brain exercise training |
| WO2016061320A2 (en) * | 2014-10-15 | 2016-04-21 | Rowan University | Timber therapy for post-traumatic stress disorder |
| EP3442940A1 (en) * | 2016-04-11 | 2019-02-20 | Clexio Biosciences Ltd. | Deuterated ketamine derivatives |
| US20200222656A1 (en) * | 2016-10-18 | 2020-07-16 | Joseph Rustick | Method for treatment of depression using synaptic pathway training |
| US10596378B2 (en) * | 2016-10-18 | 2020-03-24 | Joseph Rustick | Method for treatment of depression using synaptic pathway training |
| CA3099293A1 (en) * | 2018-05-04 | 2019-11-07 | Perception Neuroscience, Inc. | Methods of treating substance abuse |
-
2021
- 2021-03-16 EP EP21776197.2A patent/EP4126199A4/en active Pending
- 2021-03-16 MX MX2022011862A patent/MX2022011862A/es unknown
- 2021-03-16 BR BR112022019234A patent/BR112022019234A2/pt unknown
- 2021-03-16 CA CA3172981A patent/CA3172981A1/en active Pending
- 2021-03-16 IL IL296693A patent/IL296693A/en unknown
- 2021-03-16 WO PCT/US2021/022517 patent/WO2021194796A1/en unknown
-
2022
- 2022-09-19 ZA ZA2022/10356A patent/ZA202210356B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3172981A1 (en) | 2021-09-30 |
| WO2021194796A1 (en) | 2021-09-30 |
| ZA202210356B (en) | 2023-02-22 |
| IL296693A (en) | 2022-11-01 |
| EP4126199A4 (en) | 2024-04-10 |
| EP4126199A1 (en) | 2023-02-08 |
| MX2022011862A (es) | 2023-02-16 |
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