BR112022012169A2 - Cateter transesofágico para proteção térmica do esôfago - Google Patents
Cateter transesofágico para proteção térmica do esôfagoInfo
- Publication number
- BR112022012169A2 BR112022012169A2 BR112022012169A BR112022012169A BR112022012169A2 BR 112022012169 A2 BR112022012169 A2 BR 112022012169A2 BR 112022012169 A BR112022012169 A BR 112022012169A BR 112022012169 A BR112022012169 A BR 112022012169A BR 112022012169 A2 BR112022012169 A2 BR 112022012169A2
- Authority
- BR
- Brazil
- Prior art keywords
- esophagus
- thermal protection
- fluid
- biological surface
- transesophageal catheter
- Prior art date
Links
- 210000003238 esophagus Anatomy 0.000 title abstract 2
- 239000012530 fluid Substances 0.000 abstract 6
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/08—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0108—Steering means as part of the catheter or advancing means; Markers for positioning using radio-opaque or ultrasound markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0136—Handles therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00017—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids with gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00172—Connectors and adapters therefor
- A61B2018/00178—Electrical connectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
- A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
- A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
- A61B2018/00285—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00482—Digestive system
- A61B2018/00488—Esophagus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00863—Fluid flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
- A61B2090/0409—Specification of type of protection measures
- A61B2090/0427—Prevention of contact
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0247—Pressure sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0271—Thermal or temperature sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09008—Guide wires having a balloon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09166—Guide wires having radio-opaque features
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Otolaryngology (AREA)
- Biophysics (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
Abstract
CATETER TRANSESOFÁGICO PARA PROTEÇÃO TÉRMICA DO ESÔFAGO. A presente invenção refere-se a um sistema que compreende um suprimento de fluido configurado para a liberação de um fluido; um corpo oco em comunicação fluida com o suprimento de fluido, sendo que o corpo oco é configurado para ser disposto entre uma primeira superfície biológica e uma segunda superfície biológica; e um mecanismo configurado para controlar a liberação de fluido do suprimento de fluido e através do corpo oco para criar uma separação entre a primeira superfície biológica e a segunda superfície biológica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16/724,435 US20210186601A1 (en) | 2019-12-23 | 2019-12-23 | Transesophageal Catheter for Thermal Protection of the Esophagus |
PCT/IB2020/059432 WO2021130562A1 (en) | 2019-12-23 | 2020-10-07 | Transesophageal catheter for thermal protection of the esophagus |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022012169A2 true BR112022012169A2 (pt) | 2022-09-13 |
Family
ID=72944207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022012169A BR112022012169A2 (pt) | 2019-12-23 | 2020-10-07 | Cateter transesofágico para proteção térmica do esôfago |
Country Status (10)
Country | Link |
---|---|
US (1) | US20210186601A1 (pt) |
EP (1) | EP4081159A1 (pt) |
JP (1) | JP2023508149A (pt) |
KR (1) | KR20220119453A (pt) |
CN (1) | CN114845656A (pt) |
AU (1) | AU2020412385A1 (pt) |
BR (1) | BR112022012169A2 (pt) |
CA (1) | CA3165722A1 (pt) |
MX (1) | MX2022007889A (pt) |
WO (1) | WO2021130562A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20240108630A (ko) | 2023-01-02 | 2024-07-09 | 아주대학교산학협력단 | 약물 서방출형 마이크로젤의 제조방법 및 이의 생의학적 용도 |
Family Cites Families (44)
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US6690963B2 (en) | 1995-01-24 | 2004-02-10 | Biosense, Inc. | System for determining the location and orientation of an invasive medical instrument |
US6726677B1 (en) * | 1995-10-13 | 2004-04-27 | Transvascular, Inc. | Stabilized tissue penetrating catheters |
US6086582A (en) * | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
AU752243B2 (en) * | 1998-02-19 | 2002-09-12 | Curon Medical, Inc. | Electrosurgical sphincter treatment apparatus |
WO2000025850A1 (en) * | 1998-10-30 | 2000-05-11 | Windsor Ting | Medicinal agent administration catheter device |
US6458098B1 (en) * | 2000-03-17 | 2002-10-01 | Nozomu Kanesaka | Vascular therapy device |
US6400981B1 (en) | 2000-06-21 | 2002-06-04 | Biosense, Inc. | Rapid mapping of electrical activity in the heart |
US6716166B2 (en) | 2000-08-18 | 2004-04-06 | Biosense, Inc. | Three-dimensional reconstruction using ultrasound |
US6650927B1 (en) | 2000-08-18 | 2003-11-18 | Biosense, Inc. | Rendering of diagnostic imaging data on a three-dimensional map |
JP4229621B2 (ja) * | 2002-03-05 | 2009-02-25 | 修 加藤 | 薬液注入カテーテル |
US7364567B2 (en) * | 2002-06-10 | 2008-04-29 | Abbott Cardiovascular Systems Inc. | Systems and methods for detecting tissue contact and needle penetration depth |
AU2002952663A0 (en) * | 2002-11-14 | 2002-11-28 | Western Sydney Area Health Service | An intramural needle-tipped surgical device |
US7090639B2 (en) | 2003-05-29 | 2006-08-15 | Biosense, Inc. | Ultrasound catheter calibration system |
US7684850B2 (en) | 2005-01-07 | 2010-03-23 | Biosense Webster, Inc. | Reference catheter for impedance calibration |
US7869865B2 (en) | 2005-01-07 | 2011-01-11 | Biosense Webster, Inc. | Current-based position sensing |
US7604601B2 (en) | 2005-04-26 | 2009-10-20 | Biosense Webster, Inc. | Display of catheter tip with beam direction for ultrasound system |
US8870779B2 (en) | 2005-04-26 | 2014-10-28 | Biosense Webster, Inc. | Display of two-dimensional ultrasound fan |
US7963287B2 (en) * | 2005-04-28 | 2011-06-21 | Boston Scientific Scimed, Inc. | Tissue-treatment methods |
US7691086B2 (en) * | 2005-06-14 | 2010-04-06 | Tengiz Tkebuchava | Catheter for introduction of medications to the tissues of a heart or other organ |
US7848787B2 (en) | 2005-07-08 | 2010-12-07 | Biosense Webster, Inc. | Relative impedance measurement |
US7536218B2 (en) | 2005-07-15 | 2009-05-19 | Biosense Webster, Inc. | Hybrid magnetic-based and impedance-based position sensing |
US7681579B2 (en) | 2005-08-02 | 2010-03-23 | Biosense Webster, Inc. | Guided procedures for treating atrial fibrillation |
US7756576B2 (en) | 2005-08-26 | 2010-07-13 | Biosense Webster, Inc. | Position sensing and detection of skin impedance |
US8075486B2 (en) | 2006-05-03 | 2011-12-13 | Biosense Webster, Inc. | Enhanced ultrasound image display |
US7831076B2 (en) | 2006-12-08 | 2010-11-09 | Biosense Webster, Inc. | Coloring electroanatomical maps to indicate ultrasound data acquisition |
US7735349B2 (en) | 2007-01-31 | 2010-06-15 | Biosense Websters, Inc. | Correlation of ultrasound images and gated position measurements |
US8359092B2 (en) | 2007-11-29 | 2013-01-22 | Biosense Webster, Inc. | Determining locations of ganglia and plexi in the heart using complex fractionated atrial electrogram |
US8320711B2 (en) | 2007-12-05 | 2012-11-27 | Biosense Webster, Inc. | Anatomical modeling from a 3-D image and a surface mapping |
US8456182B2 (en) | 2008-09-30 | 2013-06-04 | Biosense Webster, Inc. | Current localization tracker |
US9023027B2 (en) | 2008-09-30 | 2015-05-05 | Biosense Webster (Israel), Ltd. | Current localization tracker |
US8478379B2 (en) | 2008-11-12 | 2013-07-02 | Biosense Webster, Inc. | Probe visualization based on mechanical properties |
US20160015451A1 (en) * | 2009-09-22 | 2016-01-21 | Mederi Therapeutics, Inc. | Systems and methods for treating tissue with radiofrequency energy |
US8532738B2 (en) | 2010-11-04 | 2013-09-10 | Biosense Webster (Israel), Ltd. | Visualization of catheter-tissue contact by map distortion |
US8478383B2 (en) | 2010-12-14 | 2013-07-02 | Biosense Webster (Israel), Ltd. | Probe tracking using multiple tracking methods |
US8676305B2 (en) | 2012-03-21 | 2014-03-18 | Biosense Webster (Israel) Ltd. | Automated analysis of complex fractionated electrograms |
JP6235559B2 (ja) * | 2012-04-19 | 2017-11-22 | フラクティル ラボラトリーズ インコーポレイテッド | 組織拡張デバイス、システムおよび方法 |
US9033917B2 (en) * | 2012-08-15 | 2015-05-19 | Abbott Cardiovascular Systems Inc. | Needle catheter for delivery of agents directly into vessel wall |
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DE102013212521A1 (de) * | 2013-06-27 | 2014-12-31 | Olympus Winter & Ibe Gmbh | Elektrochirurgisches Instrument und Verfahren |
US9498147B2 (en) | 2014-01-30 | 2016-11-22 | Biosense Webster (Israel) Ltd. | Enhanced ECG chart presentation |
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US11173281B2 (en) * | 2017-06-19 | 2021-11-16 | W. L. Gore & Associates, Inc. | Fenestration devices, systems, and methods |
US11179216B2 (en) * | 2018-02-15 | 2021-11-23 | Ethicon, Inc. | System(s), method(s) and device(s) for the prevention of esophageal fistula during catheter ablation |
US20190247091A1 (en) * | 2018-02-15 | 2019-08-15 | Biosense Webster (Israel) Ltd. | Transesophageal Catheter With Carbon Dioxide Delivery System For Thermal Protection Of Esophagus |
-
2019
- 2019-12-23 US US16/724,435 patent/US20210186601A1/en not_active Abandoned
-
2020
- 2020-10-07 BR BR112022012169A patent/BR112022012169A2/pt not_active Application Discontinuation
- 2020-10-07 WO PCT/IB2020/059432 patent/WO2021130562A1/en unknown
- 2020-10-07 CN CN202080089726.0A patent/CN114845656A/zh active Pending
- 2020-10-07 CA CA3165722A patent/CA3165722A1/en active Pending
- 2020-10-07 MX MX2022007889A patent/MX2022007889A/es unknown
- 2020-10-07 AU AU2020412385A patent/AU2020412385A1/en active Pending
- 2020-10-07 JP JP2022538773A patent/JP2023508149A/ja active Pending
- 2020-10-07 EP EP20793462.1A patent/EP4081159A1/en active Pending
- 2020-10-07 KR KR1020227025282A patent/KR20220119453A/ko unknown
Also Published As
Publication number | Publication date |
---|---|
MX2022007889A (es) | 2022-09-21 |
CA3165722A1 (en) | 2021-07-01 |
AU2020412385A1 (en) | 2022-08-18 |
US20210186601A1 (en) | 2021-06-24 |
EP4081159A1 (en) | 2022-11-02 |
KR20220119453A (ko) | 2022-08-29 |
CN114845656A (zh) | 2022-08-02 |
WO2021130562A1 (en) | 2021-07-01 |
JP2023508149A (ja) | 2023-03-01 |
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