BR112022011052A2 - Tratamento para leucemia mieloide aguda ou síndrome mielodisplásica - Google Patents

Tratamento para leucemia mieloide aguda ou síndrome mielodisplásica

Info

Publication number
BR112022011052A2
BR112022011052A2 BR112022011052A BR112022011052A BR112022011052A2 BR 112022011052 A2 BR112022011052 A2 BR 112022011052A2 BR 112022011052 A BR112022011052 A BR 112022011052A BR 112022011052 A BR112022011052 A BR 112022011052A BR 112022011052 A2 BR112022011052 A2 BR 112022011052A2
Authority
BR
Brazil
Prior art keywords
myeloid leukemia
myelodysplastic syndrome
acute myeloid
treatment
lymphoma
Prior art date
Application number
BR112022011052A
Other languages
English (en)
Portuguese (pt)
Inventor
R Bray Mark
M Mason Jacqueline
Fletcher Graham
Original Assignee
Univ Health Network
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Health Network filed Critical Univ Health Network
Publication of BR112022011052A2 publication Critical patent/BR112022011052A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR112022011052A 2019-12-06 2020-12-04 Tratamento para leucemia mieloide aguda ou síndrome mielodisplásica BR112022011052A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962944876P 2019-12-06 2019-12-06
PCT/CA2020/051668 WO2021108918A1 (en) 2019-12-06 2020-12-04 Treatment for acute myeloid leukemia or myelodysplastic syndrome

Publications (1)

Publication Number Publication Date
BR112022011052A2 true BR112022011052A2 (pt) 2022-08-16

Family

ID=76221282

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022011052A BR112022011052A2 (pt) 2019-12-06 2020-12-04 Tratamento para leucemia mieloide aguda ou síndrome mielodisplásica

Country Status (12)

Country Link
US (1) US12533357B2 (https=)
EP (1) EP4069246A4 (https=)
JP (1) JP2023505301A (https=)
KR (1) KR20220124177A (https=)
CN (1) CN115397429A (https=)
AU (1) AU2020396807A1 (https=)
BR (1) BR112022011052A2 (https=)
CA (1) CA3163796A1 (https=)
IL (1) IL293623A (https=)
MX (1) MX2022006910A (https=)
TW (1) TWI880995B (https=)
WO (1) WO2021108918A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7337539B2 (ja) * 2018-06-21 2023-09-04 メディヴィル・アクチエボラーグ 白血病療法のための塩基修飾シチジンヌクレオチド
JP7717842B2 (ja) 2021-05-11 2025-08-04 オリック ファーマシューティカルズ,インク. ポロ様キナーゼ4阻害剤
US20250049787A1 (en) * 2021-12-22 2025-02-13 University Health Network Treatment for acute myeloid leukemia or lymphoma

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2465971T3 (es) 2009-04-06 2014-06-09 University Health Network Inhibidores de quinasa y método para tratar cáncer con los mismos
SI2556071T1 (sl) * 2010-04-06 2016-12-30 University Health Network Kinazni inhibitorji in njihova uporaba pri zdravljenju raka
ES2706066T3 (es) * 2010-07-02 2019-03-27 Univ Health Network Procedimiento dirigido a enfermedades mutantes con PTEN y composiciones para las mismas
WO2012048411A1 (en) * 2010-10-13 2012-04-19 University Health Network Plk-4 inhibitors and method of treating cancer with same
WO2015051304A1 (en) 2013-10-04 2015-04-09 Aptose Biosciences Inc. Compositions, biomarkers and their use in treatment of cancer
HUE043194T2 (hu) * 2013-10-18 2019-08-28 Univ Health Network PLK-4 inhibitor sója és kristályformái
US9566280B2 (en) 2014-01-28 2017-02-14 Massachusetts Institute Of Technology Combination therapies and methods of use thereof for treating cancer
JP6617208B2 (ja) 2017-03-31 2019-12-11 ノバルティス アーゲー 血液腫瘍におけるhdm2−p53相互作用阻害剤の用量およびレジメン
WO2019046949A1 (en) * 2017-09-08 2019-03-14 University Health Network POLYTHERAPIES FOR INHIBITING KINASE 4 OF THE POLO TYPE
EP3720560A4 (en) * 2017-12-06 2022-01-05 Ludwig Institute for Cancer Research Ltd METHOD OF TREATMENT OF CANCER WITH PLK4 INHIBITORS

Also Published As

Publication number Publication date
CN115397429A (zh) 2022-11-25
US12533357B2 (en) 2026-01-27
WO2021108918A1 (en) 2021-06-10
AU2020396807A1 (en) 2022-07-21
CA3163796A1 (en) 2021-06-10
MX2022006910A (es) 2022-11-09
TWI880995B (zh) 2025-04-21
KR20220124177A (ko) 2022-09-13
EP4069246A4 (en) 2023-12-06
EP4069246A1 (en) 2022-10-12
TW202134237A (zh) 2021-09-16
JP2023505301A (ja) 2023-02-08
IL293623A (en) 2022-08-01
US20230010772A1 (en) 2023-01-12

Similar Documents

Publication Publication Date Title
BR112021025537A2 (pt) Azacitidina em combinação com venetoclax, gilteritinibe, midostaurina ou outros compostos para o tratamento de leucemia ou síndrome mielodisplásica
BR112022011052A2 (pt) Tratamento para leucemia mieloide aguda ou síndrome mielodisplásica
MX2020011653A (es) Métodos de tratamiento para el abuso de sustancias.
MY208545A (en) Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith
CY1117033T1 (el) Αγωγη εναντι οξειας λεμφοβλαστικης λευχαιμιας
EP4497474A3 (en) Methods of treating rheumatic diseases using trimetazidine-based compounds
EA201591687A1 (ru) Индукционная терапия ритуксимабом с последующим лечением с использованием глатирамера ацетата
CR20200148A (es) Compuestos monobactámicos cromados para el tratamiento de infecciones bacterianas
MX390084B (es) Moduladores del receptor p2x3 y p2x2/3 de diaminopirimidina para usarse en el tratamiento de la tos.
BR112023010885A2 (pt) Terapia de combinação de anti-cd19
BR112023001615A2 (pt) Tratamento para enxaqueca
MX2025010357A (es) Degradador de irak4, y uso del mismo
PH12021550713A1 (en) Medicament for the treatment of chronic cough
PH12021550452A1 (en) Methods of treating mycobacterial infections using tetracycline compounds
MX2018014080A (es) Uso de compuesto de carbamato para prevenir o tratar fibromialgia o sindrome funcional asociado con fibromialgia.
MX2022005522A (es) Formas de sal de un receptor de componente c5a de complemento.
BR112021020962A2 (pt) Métodos de tratamento de prurido
PH12019501566B1 (en) Amide compounds and use thereof
EA201892098A1 (ru) Соединение, обладающее ингибирующей мутантную idh активностью, способ его получения и применения
MX2022006229A (es) Composiciones y metodos para el tratamiento de resistencia a la insulina.
EA202193276A1 (ru) Способы лечения холангиокарциномы
PH12018500999A1 (en) Sodium channel blocker
MX379576B (es) Derivados de azetidina
EA202190751A1 (ru) Способы лечения миелопролиферативных расстройств
MX2021004085A (es) El uso de un agonista inverso de h3r para el tratamiento de la somnolencia diurna excesiva asociada con la enfermedad de parkinson (ep).

Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]