BR112022003149A2 - Lurbinectedina no tratamento de mesotelioma maligno - Google Patents

Lurbinectedina no tratamento de mesotelioma maligno

Info

Publication number
BR112022003149A2
BR112022003149A2 BR112022003149A BR112022003149A BR112022003149A2 BR 112022003149 A2 BR112022003149 A2 BR 112022003149A2 BR 112022003149 A BR112022003149 A BR 112022003149A BR 112022003149 A BR112022003149 A BR 112022003149A BR 112022003149 A2 BR112022003149 A2 BR 112022003149A2
Authority
BR
Brazil
Prior art keywords
lurbinectedin
treatment
malignant mesothelioma
mesothelioma
malignant
Prior art date
Application number
BR112022003149A
Other languages
English (en)
Inventor
Ioannis Metaxas
Von Moos Roger
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of BR112022003149A2 publication Critical patent/BR112022003149A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995Pyrazines or piperazines forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

lurbinectedina no tratamento de mesotelioma maligno. a presente invenção refere-se ao uso de lurbinectedina no tratamento de mesotelioma maligno é fornecido.
BR112022003149A 2019-09-03 2020-09-03 Lurbinectedina no tratamento de mesotelioma maligno BR112022003149A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19382749 2019-09-03
PCT/EP2020/074689 WO2021043949A1 (en) 2019-09-03 2020-09-03 Lurbinectedin in the treatment of malignant mesothelioma

Publications (1)

Publication Number Publication Date
BR112022003149A2 true BR112022003149A2 (pt) 2022-05-17

Family

ID=67902455

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022003149A BR112022003149A2 (pt) 2019-09-03 2020-09-03 Lurbinectedina no tratamento de mesotelioma maligno

Country Status (13)

Country Link
US (1) US20230241041A1 (pt)
EP (1) EP4025217A1 (pt)
JP (1) JP2022547049A (pt)
KR (1) KR20220054872A (pt)
CN (1) CN114423429A (pt)
AU (1) AU2020342483A1 (pt)
BR (1) BR112022003149A2 (pt)
CA (1) CA3148690A1 (pt)
CL (1) CL2022000522A1 (pt)
IL (1) IL290656A (pt)
MX (1) MX2022002699A (pt)
TW (1) TW202116783A (pt)
WO (1) WO2021043949A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022048775A1 (en) * 2020-09-04 2022-03-10 Pharma Mar, S.A. Combination of lurbinectedin and immune checkpoint inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0119243D0 (en) 2001-08-07 2001-10-03 Pharma Mar Sa Antitumoral analogs of ET-743
CN106974902A (zh) * 2016-01-18 2017-07-25 贵州益佰制药股份有限公司 洛铂在制备治疗恶性胸膜间皮瘤药物中的应用

Also Published As

Publication number Publication date
KR20220054872A (ko) 2022-05-03
AU2020342483A1 (en) 2022-04-14
MX2022002699A (es) 2022-04-11
EP4025217A1 (en) 2022-07-13
CN114423429A (zh) 2022-04-29
JP2022547049A (ja) 2022-11-10
WO2021043949A1 (en) 2021-03-11
TW202116783A (zh) 2021-05-01
IL290656A (en) 2022-04-01
US20230241041A1 (en) 2023-08-03
CA3148690A1 (en) 2021-03-11
CL2022000522A1 (es) 2022-10-21

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