BR112022002048A2 - Eficiência de coleta de emissão aumentada em dispositivos ópticos integrados - Google Patents
Eficiência de coleta de emissão aumentada em dispositivos ópticos integradosInfo
- Publication number
- BR112022002048A2 BR112022002048A2 BR112022002048A BR112022002048A BR112022002048A2 BR 112022002048 A2 BR112022002048 A2 BR 112022002048A2 BR 112022002048 A BR112022002048 A BR 112022002048A BR 112022002048 A BR112022002048 A BR 112022002048A BR 112022002048 A2 BR112022002048 A2 BR 112022002048A2
- Authority
- BR
- Brazil
- Prior art keywords
- microdisk
- integrated device
- optical
- collection efficiency
- optical devices
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title abstract 6
- 239000012491 analyte Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000003989 dielectric material Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
- G01N21/6454—Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
- G01N21/7746—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the waveguide coupled to a cavity resonator
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
- G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
- G02B6/122—Basic optical elements, e.g. light-guiding paths
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
- G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
- G02B6/13—Integrated optical circuits characterised by the manufacturing method
- G02B6/136—Integrated optical circuits characterised by the manufacturing method by etching
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L27/00—Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate
- H01L27/14—Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including semiconductor components sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation
- H01L27/144—Devices controlled by radiation
- H01L27/146—Imager structures
- H01L27/14601—Structural or functional details thereof
- H01L27/1462—Coatings
- H01L27/14621—Colour filter arrangements
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L27/00—Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate
- H01L27/14—Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including semiconductor components sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation
- H01L27/144—Devices controlled by radiation
- H01L27/146—Imager structures
- H01L27/14601—Structural or functional details thereof
- H01L27/14625—Optical elements or arrangements associated with the device
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L31/00—Semiconductor devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof; Details thereof
- H01L31/02—Details
- H01L31/0232—Optical elements or arrangements associated with the device
- H01L31/02327—Optical elements or arrangements associated with the device the optical elements being integrated or being directly associated to the device, e.g. back reflectors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6471—Special filters, filter wheel
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7769—Measurement method of reaction-produced change in sensor
- G01N2021/7786—Fluorescence
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
- G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
- G02B2006/12083—Constructional arrangements
- G02B2006/12109—Filter
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
- G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
- G02B2006/12133—Functions
- G02B2006/12138—Sensor
Abstract
eficiência de coleta de emissão aumentada em dispositivos ópticos integrados. a presente invenção refere-se a aparelho e métodos para melhorar a coleta de sinal óptico em um dispositivo integrado que são descritos. um microdisco (1-605) pode ser formado em um dispositivo integrado e aumentar a coleta e/ou concentração de radiação incidente no microdisco (1-605) e irradiada de novo pelo microdisco (1-605). um exemplo de dispositivo integrado que pode incluir um microdisco (1-605) pode ser usado para detecção e/ou análise de analito. tal dispositivo integrado pode incluir uma pluralidade de pixels, cada um tendo uma câmara de reação (1-130) para receber uma amostra a ser analisada, um microdisco óptico (1-605) e um sensor óptico (1-122) configurado para detectar a emissão óptica da câmara de reação (1-130). o microdisco (1-605) pode compreender um material dielétrico com um primeiro índice de refração que está embutido em um ou mais materiais circundantes (1-610) com um ou mais valores de índice de refração diferentes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962884395P | 2019-08-08 | 2019-08-08 | |
PCT/US2020/045101 WO2021026291A1 (en) | 2019-08-08 | 2020-08-06 | Increased emission collection efficiency in integrated optical devices |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022002048A2 true BR112022002048A2 (pt) | 2022-06-07 |
Family
ID=72292612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022002048A BR112022002048A2 (pt) | 2019-08-08 | 2020-08-06 | Eficiência de coleta de emissão aumentada em dispositivos ópticos integrados |
Country Status (12)
Country | Link |
---|---|
US (1) | US11454758B2 (pt) |
EP (1) | EP4004525A1 (pt) |
JP (1) | JP2022544476A (pt) |
KR (1) | KR20220042449A (pt) |
CN (1) | CN114514420A (pt) |
AU (1) | AU2020326781A1 (pt) |
BR (1) | BR112022002048A2 (pt) |
CA (1) | CA3149492A1 (pt) |
IL (1) | IL290375A (pt) |
MX (1) | MX2022001614A (pt) |
TW (1) | TW202114238A (pt) |
WO (1) | WO2021026291A1 (pt) |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5814565A (en) | 1995-02-23 | 1998-09-29 | University Of Utah Research Foundation | Integrated optic waveguide immunosensor |
US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
WO2001084197A1 (en) | 2000-04-28 | 2001-11-08 | Edgelight Biosciences, Inc. | Micro-array evanescent wave fluorescence detection device |
US6917726B2 (en) | 2001-09-27 | 2005-07-12 | Cornell Research Foundation, Inc. | Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes |
FR2813121A1 (fr) | 2000-08-21 | 2002-02-22 | Claude Weisbuch | Dispositif perfectionne de support d'elements chromophores |
US7738086B2 (en) | 2005-05-09 | 2010-06-15 | The Trustees Of Columbia University In The City Of New York | Active CMOS biosensor chip for fluorescent-based detection |
US7426322B2 (en) | 2005-07-20 | 2008-09-16 | Searete Llc. | Plasmon photocatalysis |
US8975216B2 (en) | 2006-03-30 | 2015-03-10 | Pacific Biosciences Of California | Articles having localized molecules disposed thereon and methods of producing same |
US8207509B2 (en) | 2006-09-01 | 2012-06-26 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
AU2007289057C1 (en) | 2006-09-01 | 2014-01-16 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
FR2908888B1 (fr) | 2006-11-21 | 2012-08-03 | Centre Nat Rech Scient | Dispositif pour la detection exaltee de l'emission d'une particule cible |
WO2009082706A1 (en) | 2007-12-21 | 2009-07-02 | The Trustees Of Columbia University In The City Of New York | Active cmos sensor array for electrochemical biomolecular detection |
AU2009292629B2 (en) | 2008-09-16 | 2014-03-20 | Pacific Biosciences Of California, Inc. | Substrates and optical systems and methods of use thereof |
US8278728B2 (en) | 2009-10-17 | 2012-10-02 | Florida Institute Of Technology | Array of concentric CMOS photodiodes for detection and de-multiplexing of spatially modulated optical channels |
US8994946B2 (en) * | 2010-02-19 | 2015-03-31 | Pacific Biosciences Of California, Inc. | Integrated analytical system and method |
AU2011217862B9 (en) | 2010-02-19 | 2014-07-10 | Pacific Biosciences Of California, Inc. | Integrated analytical system and method |
US8865078B2 (en) | 2010-06-11 | 2014-10-21 | Industrial Technology Research Institute | Apparatus for single-molecule detection |
EP3305400A3 (en) | 2011-10-28 | 2018-06-06 | Illumina, Inc. | Microarray fabrication system and method |
US9606060B2 (en) | 2012-01-13 | 2017-03-28 | California Institute Of Technology | Filterless time-domain detection of one or more fluorophores |
US9372308B1 (en) * | 2012-06-17 | 2016-06-21 | Pacific Biosciences Of California, Inc. | Arrays of integrated analytical devices and methods for production |
US9223084B2 (en) | 2012-12-18 | 2015-12-29 | Pacific Biosciences Of California, Inc. | Illumination of optical analytical devices |
EP2959283B1 (en) * | 2013-02-22 | 2022-08-17 | Pacific Biosciences of California, Inc. | Integrated illumination of optical analytical devices |
WO2015074001A1 (en) | 2013-11-17 | 2015-05-21 | Quantum-Si Incorporated | Optical system and assay chip for probing, detecting and analyzing molecules |
US9765395B2 (en) | 2014-04-28 | 2017-09-19 | Nanomedical Diagnostics, Inc. | System and method for DNA sequencing and blood chemistry analysis |
AU2015300778B2 (en) | 2014-08-08 | 2021-02-25 | Quantum-Si Incorporated | Optical system and assay chip for probing, detecting, and analyzing molecules |
MX2017001808A (es) | 2014-08-08 | 2018-02-08 | Quantum Si Inc | Dispositivo integrado con fuente de luz externa para el sondeo, deteccion y analisis de moleculas. |
US9666748B2 (en) | 2015-01-14 | 2017-05-30 | International Business Machines Corporation | Integrated on chip detector and zero waveguide module structure for use in DNA sequencing |
US20160211390A1 (en) * | 2015-01-16 | 2016-07-21 | Personal Genomics, Inc. | Optical Sensor with Light-Guiding Feature and Method for Preparing the Same |
WO2016149397A1 (en) | 2015-03-16 | 2016-09-22 | Pacific Biosciences Of California, Inc. | Integrated devices and systems for free-space optical coupling |
US10174363B2 (en) * | 2015-05-20 | 2019-01-08 | Quantum-Si Incorporated | Methods for nucleic acid sequencing |
US9778191B2 (en) * | 2016-02-05 | 2017-10-03 | Personal Genomics, Inc. | Optical sensing module |
-
2020
- 2020-08-06 KR KR1020227007666A patent/KR20220042449A/ko active Search and Examination
- 2020-08-06 AU AU2020326781A patent/AU2020326781A1/en active Pending
- 2020-08-06 EP EP20764814.8A patent/EP4004525A1/en active Pending
- 2020-08-06 TW TW109126727A patent/TW202114238A/zh unknown
- 2020-08-06 CN CN202080069903.9A patent/CN114514420A/zh active Pending
- 2020-08-06 BR BR112022002048A patent/BR112022002048A2/pt not_active Application Discontinuation
- 2020-08-06 WO PCT/US2020/045101 patent/WO2021026291A1/en unknown
- 2020-08-06 CA CA3149492A patent/CA3149492A1/en active Pending
- 2020-08-06 MX MX2022001614A patent/MX2022001614A/es unknown
- 2020-08-06 JP JP2022507738A patent/JP2022544476A/ja active Pending
- 2020-08-07 US US16/987,937 patent/US11454758B2/en active Active
-
2022
- 2022-02-06 IL IL290375A patent/IL290375A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2022544476A (ja) | 2022-10-19 |
AU2020326781A1 (en) | 2022-03-17 |
CN114514420A (zh) | 2022-05-17 |
KR20220042449A (ko) | 2022-04-05 |
IL290375A (en) | 2022-04-01 |
TW202114238A (zh) | 2021-04-01 |
MX2022001614A (es) | 2022-05-26 |
US11454758B2 (en) | 2022-09-27 |
EP4004525A1 (en) | 2022-06-01 |
CA3149492A1 (en) | 2021-02-11 |
WO2021026291A1 (en) | 2021-02-11 |
US20210041625A1 (en) | 2021-02-11 |
US20220397720A1 (en) | 2022-12-15 |
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